PMC:1064895 / 16579-16783 JSONTXT

{"project":"test3","denotations":[{"id":"T11672","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T11671","span":{"begin":135,"end":143},"obj":"Gene_expression"},{"id":"T11670","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T11669","span":{"begin":62,"end":72},"obj":"Gene_expression"},{"id":"T11668","span":{"begin":56,"end":61},"obj":"Protein"},{"id":"T11667","span":{"begin":44,"end":55},"obj":"Positive_regulation"},{"id":"T11653","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T11652","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T11651","span":{"begin":56,"end":61},"obj":"Protein"}],"relations":[{"id":"R6322","pred":"themeOf","subj":"T11668","obj":"T11669"},{"id":"R6323","pred":"themeOf","subj":"T11669","obj":"T11667"},{"id":"R6324","pred":"themeOf","subj":"T11672","obj":"T11671"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T12073","span":{"begin":44,"end":55},"obj":"Positive_regulation"},{"id":"T12072","span":{"begin":135,"end":143},"obj":"Gene_expression"},{"id":"T12071","span":{"begin":62,"end":72},"obj":"Gene_expression"},{"id":"T12064","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T12063","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T12062","span":{"begin":56,"end":61},"obj":"Protein"}],"relations":[{"id":"R6513","pred":"themeOf","subj":"T12062","obj":"T12071"},{"id":"R6514","pred":"themeOf","subj":"T12064","obj":"T12072"},{"id":"R6517","pred":"themeOf","subj":"T12071","obj":"T12073"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T12356","span":{"begin":135,"end":143},"obj":"Gene_expression"},{"id":"T12355","span":{"begin":44,"end":55},"obj":"Positive_regulation"},{"id":"T12354","span":{"begin":62,"end":72},"obj":"Gene_expression"},{"id":"T12346","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T12345","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T12344","span":{"begin":56,"end":61},"obj":"Protein"}],"relations":[{"id":"R6732","pred":"themeOf","subj":"T12344","obj":"T12354"},{"id":"R6733","pred":"themeOf","subj":"T12346","obj":"T12356"},{"id":"R6736","pred":"themeOf","subj":"T12354","obj":"T12355"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"biosemtest","denotations":[{"id":"T11760","span":{"begin":158,"end":171},"obj":"UMLS/C0332232"},{"id":"T11756","span":{"begin":151,"end":156},"obj":"UMLS/C1825592"},{"id":"T11751","span":{"begin":58,"end":74},"obj":"UMLS/C1819444"},{"id":"T11733","span":{"begin":146,"end":150},"obj":"UMLS/C0205172"},{"id":"T11732","span":{"begin":151,"end":156},"obj":"UMLS/C1623218"},{"id":"T11719","span":{"begin":99,"end":110},"obj":"UMLS/C1947911"},{"id":"T11717","span":{"begin":146,"end":150},"obj":"UMLS/C0439064"},{"id":"T11706","span":{"begin":75,"end":80},"obj":"UMLS/C0547043"},{"id":"T11698","span":{"begin":14,"end":19},"obj":"UMLS/C0039224"},{"id":"T11697","span":{"begin":151,"end":156},"obj":"UMLS/C1522571"},{"id":"T11688","span":{"begin":99,"end":110},"obj":"UMLS/C0453882"},{"id":"T11687","span":{"begin":99,"end":110},"obj":"UMLS/C0205195"},{"id":"T11682","span":{"begin":14,"end":19},"obj":"UMLS/C1706073"},{"id":"T11681","span":{"begin":14,"end":19},"obj":"UMLS/C1706074"},{"id":"T11680","span":{"begin":151,"end":156},"obj":"UMLS/C0384648"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

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{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T11956","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T11955","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T11954","span":{"begin":56,"end":61},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T12055","span":{"begin":117,"end":121},"obj":"http://www.uniprot.org/uniprot/P10747"},{"id":"T12052","span":{"begin":194,"end":197},"obj":"http://www.uniprot.org/uniprot/P09693"},{"id":"T12051","span":{"begin":131,"end":134},"obj":"http://www.uniprot.org/uniprot/P09693"},{"id":"T12050","span":{"begin":26,"end":29},"obj":"http://www.uniprot.org/uniprot/P09693"},{"id":"T12045","span":{"begin":194,"end":197},"obj":"http://www.uniprot.org/uniprot/P07766"},{"id":"T12044","span":{"begin":131,"end":134},"obj":"http://www.uniprot.org/uniprot/P07766"},{"id":"T12043","span":{"begin":26,"end":29},"obj":"http://www.uniprot.org/uniprot/P07766"},{"id":"T12038","span":{"begin":194,"end":197},"obj":"http://www.uniprot.org/uniprot/P04234"},{"id":"T12037","span":{"begin":131,"end":134},"obj":"http://www.uniprot.org/uniprot/P04234"},{"id":"T12036","span":{"begin":26,"end":29},"obj":"http://www.uniprot.org/uniprot/P04234"},{"id":"T12031","span":{"begin":194,"end":197},"obj":"http://www.uniprot.org/uniprot/P20963"},{"id":"T12030","span":{"begin":131,"end":134},"obj":"http://www.uniprot.org/uniprot/P20963"},{"id":"T12029","span":{"begin":26,"end":29},"obj":"http://www.uniprot.org/uniprot/P20963"},{"id":"T12024","span":{"begin":149,"end":154},"obj":"http://www.uniprot.org/uniprot/Q16552"},{"id":"T12023","span":{"begin":56,"end":61},"obj":"http://www.uniprot.org/uniprot/Q16552"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"GO-BP","denotations":[{"id":"T11770","span":{"begin":56,"end":72},"obj":"http://purl.obolibrary.org/obo/GO_0032620"},{"id":"T11767","span":{"begin":56,"end":72},"obj":"http://purl.obolibrary.org/obo/GO_0032660"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"GO-MF","denotations":[{"id":"T11964","span":{"begin":149,"end":154},"obj":"http://purl.obolibrary.org/obo/GO_0030367"},{"id":"T11963","span":{"begin":56,"end":61},"obj":"http://purl.obolibrary.org/obo/GO_0030367"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"sentences","denotations":[{"id":"T11764","span":{"begin":0,"end":204},"obj":"Sentence"},{"id":"T122","span":{"begin":0,"end":204},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"simple1","denotations":[{"id":"T12016","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T12015","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T12014","span":{"begin":56,"end":61},"obj":"Protein"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"DLUT931","denotations":[{"id":"T12094","span":{"begin":44,"end":55},"obj":"Positive_regulation"},{"id":"T12093","span":{"begin":135,"end":143},"obj":"Gene_expression"},{"id":"T12092","span":{"begin":62,"end":72},"obj":"Gene_expression"},{"id":"T12083","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T12082","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T12081","span":{"begin":56,"end":61},"obj":"Protein"}],"relations":[{"id":"R6523","pred":"themeOf","subj":"T12081","obj":"T12092"},{"id":"R6524","pred":"themeOf","subj":"T12083","obj":"T12093"},{"id":"R6530","pred":"themeOf","subj":"T12092","obj":"T12094"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T12336","span":{"begin":56,"end":78},"obj":"Gene_expression"},{"id":"T12334","span":{"begin":93,"end":183},"obj":"Gene_expression"},{"id":"T12333","span":{"begin":9,"end":87},"obj":"Positive_regulation"},{"id":"T12325","span":{"begin":184,"end":197},"obj":"Protein"},{"id":"T12324","span":{"begin":126,"end":134},"obj":"Protein"},{"id":"T12321","span":{"begin":144,"end":183},"obj":"Protein"},{"id":"T12319","span":{"begin":21,"end":29},"obj":"Protein"},{"id":"T12316","span":{"begin":56,"end":61},"obj":"Protein"},{"id":"T12312","span":{"begin":112,"end":121},"obj":"Protein"}],"relations":[{"id":"R6722","pred":"themeOf","subj":"T12316","obj":"T12336"},{"id":"R6723","pred":"causeOf","subj":"T12319","obj":"T12333"},{"id":"R6724","pred":"themeOf","subj":"T12321","obj":"T12334"},{"id":"R6726","pred":"themeOf","subj":"T12336","obj":"T12333"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T12240","span":{"begin":203,"end":204},"obj":"."},{"id":"T12239","span":{"begin":198,"end":203},"obj":"RB"},{"id":"T12238","span":{"begin":189,"end":197},"obj":"JJ"},{"id":"T12237","span":{"begin":184,"end":188},"obj":"IN"},{"id":"T12236","span":{"begin":182,"end":183},"obj":"-RRB-"},{"id":"T12235","span":{"begin":178,"end":182},"obj":"VB"},{"id":"T12234","span":{"begin":177,"end":178},"obj":":"},{"id":"T12233","span":{"begin":175,"end":177},"obj":"SYM"},{"id":"T12232","span":{"begin":170,"end":175},"obj":"CD"},{"id":"T12231","span":{"begin":156,"end":169},"obj":"RB"},{"id":"T12230","span":{"begin":155,"end":156},"obj":"-LRB-"},{"id":"T12229","span":{"begin":149,"end":154},"obj":"JJ"},{"id":"T12228","span":{"begin":144,"end":148},"obj":"RBR"},{"id":"T12227","span":{"begin":135,"end":143},"obj":"VBN"},{"id":"T12226","span":{"begin":126,"end":134},"obj":"JJ"},{"id":"T12225","span":{"begin":122,"end":125},"obj":"CC"},{"id":"T12224","span":{"begin":112,"end":121},"obj":"JJ"},{"id":"T12223","span":{"begin":109,"end":111},"obj":"IN"},{"id":"T12222","span":{"begin":97,"end":108},"obj":"NN"},{"id":"T12221","span":{"begin":93,"end":96},"obj":"DT"},{"id":"T12220","span":{"begin":89,"end":92},"obj":"CC"},{"id":"T12219","span":{"begin":87,"end":88},"obj":","},{"id":"T12218","span":{"begin":79,"end":87},"obj":"CD"},{"id":"T12217","span":{"begin":76,"end":78},"obj":"TO"},{"id":"T12216","span":{"begin":73,"end":75},"obj":"IN"},{"id":"T12215","span":{"begin":62,"end":72},"obj":"NN"},{"id":"T12214","span":{"begin":56,"end":61},"obj":"NN"},{"id":"T12213","span":{"begin":44,"end":55},"obj":"JJ"},{"id":"T12212","span":{"begin":30,"end":43},"obj":"RB"},{"id":"T12211","span":{"begin":21,"end":29},"obj":"JJ"},{"id":"T12210","span":{"begin":19,"end":20},"obj":","},{"id":"T12209","span":{"begin":18,"end":19},"obj":"CD"},{"id":"T12208","span":{"begin":12,"end":17},"obj":"NNP"},{"id":"T12207","span":{"begin":9,"end":11},"obj":"IN"},{"id":"T12206","span":{"begin":3,"end":8},"obj":"VBN"},{"id":"T12205","span":{"begin":0,"end":2},"obj":"IN"}],"relations":[{"id":"R6633","pred":"mark","subj":"T12205","obj":"T12206"},{"id":"R6634","pred":"advcl","subj":"T12206","obj":"T12227"},{"id":"R6635","pred":"prep","subj":"T12207","obj":"T12206"},{"id":"R6636","pred":"pobj","subj":"T12208","obj":"T12207"},{"id":"R6637","pred":"nummod","subj":"T12209","obj":"T12208"},{"id":"R6638","pred":"punct","subj":"T12210","obj":"T12227"},{"id":"R6639","pred":"nmod","subj":"T12211","obj":"T12215"},{"id":"R6640","pred":"advmod","subj":"T12212","obj":"T12213"},{"id":"R6641","pred":"nmod","subj":"T12213","obj":"T12215"},{"id":"R6642","pred":"compound","subj":"T12214","obj":"T12215"},{"id":"R6643","pred":"nsubj","subj":"T12215","obj":"T12227"},{"id":"R6644","pred":"prep","subj":"T12216","obj":"T12215"},{"id":"R6645","pred":"prep","subj":"T12217","obj":"T12216"},{"id":"R6646","pred":"pobj","subj":"T12218","obj":"T12217"},{"id":"R6647","pred":"punct","subj":"T12219","obj":"T12215"},{"id":"R6648","pred":"cc","subj":"T12220","obj":"T12215"},{"id":"R6649","pred":"det","subj":"T12221","obj":"T12222"},{"id":"R6650","pred":"conj","subj":"T12222","obj":"T12215"},{"id":"R6651","pred":"prep","subj":"T12223","obj":"T12222"},{"id":"R6652","pred":"amod","subj":"T12224","obj":"T12227"},{"id":"R6653","pred":"cc","subj":"T12225","obj":"T12224"},{"id":"R6654","pred":"conj","subj":"T12226","obj":"T12224"},{"id":"R6655","pred":"ROOT","subj":"T12227","obj":"T12227"},{"id":"R6656","pred":"advmod","subj":"T12228","obj":"T12229"},{"id":"R6657","pred":"dobj","subj":"T12229","obj":"T12227"},{"id":"R6658","pred":"punct","subj":"T12230","obj":"T12235"},{"id":"R6659","pred":"advmod","subj":"T12231","obj":"T12232"},{"id":"R6660","pred":"nummod","subj":"T12232","obj":"T12235"},{"id":"R6661","pred":"punct","subj":"T12233","obj":"T12235"},{"id":"R6662","pred":"punct","subj":"T12234","obj":"T12235"},{"id":"R6663","pred":"appos","subj":"T12235","obj":"T12229"},{"id":"R6664","pred":"punct","subj":"T12236","obj":"T12235"},{"id":"R6665","pred":"prep","subj":"T12237","obj":"T12229"},{"id":"R6666","pred":"pobj","subj":"T12238","obj":"T12237"},{"id":"R6667","pred":"advmod","subj":"T12239","obj":"T12238"},{"id":"R6668","pred":"punct","subj":"T12240","obj":"T12227"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T12001","span":{"begin":44,"end":55},"obj":"Positive_regulation"},{"id":"T12000","span":{"begin":135,"end":143},"obj":"Gene_expression"},{"id":"T11999","span":{"begin":135,"end":143},"obj":"Gene_expression"},{"id":"T11998","span":{"begin":62,"end":72},"obj":"Gene_expression"},{"id":"T11997","span":{"begin":194,"end":197},"obj":"Protein"},{"id":"T11996","span":{"begin":144,"end":154},"obj":"Protein"},{"id":"T11995","span":{"begin":126,"end":134},"obj":"Protein"},{"id":"T11994","span":{"begin":112,"end":121},"obj":"Protein"},{"id":"T11993","span":{"begin":56,"end":61},"obj":"Protein"},{"id":"T11992","span":{"begin":21,"end":29},"obj":"Protein"},{"id":"T11991","span":{"begin":12,"end":19},"obj":"Protein"}],"relations":[{"id":"R6503","pred":"causeOf","subj":"T11992","obj":"T12001"},{"id":"R6504","pred":"themeOf","subj":"T11993","obj":"T11998"},{"id":"R6505","pred":"themeOf","subj":"T11996","obj":"T11999"},{"id":"R6506","pred":"themeOf","subj":"T11997","obj":"T12000"},{"id":"R6507","pred":"themeOf","subj":"T11998","obj":"T12001"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}

{"project":"testone","denotations":[{"id":"T11643","span":{"begin":135,"end":143},"obj":"Gene_expression"},{"id":"T11642","span":{"begin":62,"end":72},"obj":"Gene_expression"},{"id":"T11641","span":{"begin":44,"end":55},"obj":"Positive_regulation"},{"id":"T11633","span":{"begin":149,"end":154},"obj":"Protein"},{"id":"T11632","span":{"begin":117,"end":121},"obj":"Protein"},{"id":"T11631","span":{"begin":56,"end":61},"obj":"Protein"}],"relations":[{"id":"R6310","pred":"themeOf","subj":"T11631","obj":"T11642"},{"id":"R6311","pred":"themeOf","subj":"T11633","obj":"T11643"},{"id":"R6315","pred":"themeOf","subj":"T11642","obj":"T11641"}],"text":"As shown in Table 1, anti-CD3 significantly upregulated IL-17 production up to 3.7-fold, and the combination of anti-CD28 and anti-CD3 produced more IL-17 (approximately 1.3-1.5-fold) than anti-CD3 alone."}