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PMC:1064873 / 4402-5230 JSONTXT

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LappsTest

Id Subject Object Predicate Lexical cue
T2220 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T2219 764-768 Protein denotes IL-1
T2218 757-761 Protein denotes TNF-
T2217 679-686 Protein denotes IL-10R1
T2216 617-621 Protein denotes IL-1
T2215 607-611 Protein denotes TNF-
T2214 505-510 Protein denotes IL-10
T2213 410-415 Protein denotes IL-10

2_test

Id Subject Object Predicate Lexical cue
15535835-8163935-4156873 360-362 8163935 denotes 12
15535835-11046056-4156874 644-646 11046056 denotes 13
15535835-12782719-4156875 647-649 12782719 denotes 14
15535835-10553089-4156876 824-826 10553089 denotes 15

biosemtest

Id Subject Object Predicate Lexical cue
T3106 512-521 UMLS/C0037083 denotes ignaling
T3105 457-476 UMLS/C0037083 denotes ignal transduction
T3102 431-440 UMLS/C0443264 denotes odulated
T3098 105-111 UMLS/C1706309 denotes oints.
T3083 105-111 UMLS/C0022417 denotes oints.
T3060 51-61 UMLS/C1999216 denotes nhibitors
T3043 692-701 UMLS/C0547047 denotes creased i
T3039 554-561 UMLS/C1547296 denotes hronic
T3022 105-111 UMLS/C0392905 denotes oints.
T3016 105-111 UMLS/C1269611 denotes oints.
T3004 401-407 UMLS/C0441472 denotes ction
T3001 353-359 UMLS/C0441471 denotes vents
T2993 214-222 UMLS/C1513916 denotes egative
T2992 88-98 UMLS/C1561573 denotes uantities
T2991 214-222 UMLS/C0205160 denotes egative
T2982 562-573 UMLS/C0332157 denotes xposure to
T2971 506-511 UMLS/C0085295 denotes L-10
T2970 411-416 UMLS/C0085295 denotes L-10
T2969 113-118 UMLS/C0085295 denotes L-10,
T2960 692-701 UMLS/C0392756 denotes creased i
T2944 554-561 UMLS/C1555457 denotes hronic
T2925 82-87 UMLS/C0549177 denotes arge
T2923 525-533 UMLS/C0221099 denotes mpaired
T2913 383-400 UMLS/C0003209 denotes nti-inflammatory
T2912 10-27 UMLS/C0003209 denotes nti-inflammatory
T2909 223-232 UMLS/C1704734 denotes egulator
T2907 223-232 UMLS/C1704735 denotes egulator
T2903 203-208 UMLS/C0205309 denotes nown
T2831 525-533 UMLS/C0684336 denotes mpaired
T2827 692-701 UMLS/C0205216 denotes creased i
T2823 431-440 UMLS/C1709059 denotes odulated
T2817 554-561 UMLS/C0205191 denotes hronic
T2799 484-504 UMLS/C0021376 denotes hronic inflammation.
T2789 537-548 UMLS/C1550652 denotes acrophages
T2788 237-247 UMLS/C1550652 denotes acrophage
T2787 132-143 UMLS/C1550652 denotes acrophages
T2768 88-98 UMLS/C1554108 denotes uantities
T2746 291-303 UMLS/C0205412 denotes nsufficient
T2743 747-755 UMLS/C0150312 denotes esence o
T2742 71-78 UMLS/C0150312 denotes resent
T2732 692-701 UMLS/C0442797 denotes creased i
T2730 369-377 UMLS/C1883712 denotes ddition,
T2711 767-771 UMLS/C1522428 denotes 1, a
T2710 619-623 UMLS/C1522428 denotes -1 a
T2708 198-202 UMLS/C1522427 denotes est
T2707 448-453 UMLS/C0456079 denotes evel
T2706 282-287 UMLS/C0456079 denotes evel
T2699 767-771 UMLS/C1149212 denotes 1, a
T2698 619-623 UMLS/C1149212 denotes -1 a
T2696 291-303 UMLS/C0231180 denotes nsufficient
T2692 506-511 UMLS/C1149215 denotes L-10
T2691 411-416 UMLS/C1149215 denotes L-10
T2690 113-118 UMLS/C1149215 denotes L-10,
T2677 448-453 UMLS/C0441889 denotes evel
T2676 282-287 UMLS/C0441889 denotes evel
T2655 667-677 UMLS/C0185117 denotes pression o
T2654 271-281 UMLS/C0185117 denotes xpression
T3231 628-644 UMLS/C0003313 denotes mune complexes [
T3228 105-111 UMLS/C0444497 denotes oints.
T3210 88-98 UMLS/C1265611 denotes uantities
T3203 307-321 UMLS/C1707527 denotes ounterbalance
T3195 537-548 UMLS/C0024432 denotes acrophages
T3194 237-247 UMLS/C0024432 denotes acrophage
T3193 132-143 UMLS/C0024432 denotes acrophages
T3163 82-87 UMLS/C1704243 denotes arge
T3159 82-87 UMLS/C0443228 denotes arge
T3147 705-719 UMLS/C0039097 denotes novial fluid d
T3138 791-827 UMLS/C0079784 denotes phage colony-stimulating factor [15]
T3121 158-165 UMLS/C0039194 denotes cells
T2890 654-666 UMLS/C0699040 denotes ll surface e
T2879 252-261 UMLS/C0242632 denotes h1 cells,
T2856 512-521 UMLS/C1710082 denotes ignaling
T2845 71-78 UMLS/C0449450 denotes resent
T2599 506-511 UMLS/C1522550 denotes L-10
T2598 411-416 UMLS/C1522550 denotes L-10
T2597 113-118 UMLS/C1522550 denotes L-10,
T2585 506-511 UMLS/C1334098 denotes L-10
T2584 411-416 UMLS/C1334098 denotes L-10
T2583 113-118 UMLS/C1334098 denotes L-10,
T2570 590-599 UMLS/C1524094 denotes ytokines
T2569 42-50 UMLS/C1524094 denotes ytokine
T2568 28-37 UMLS/C1524094 denotes ytokines
T2561 791-827 UMLS/C1524095 denotes phage colony-stimulating factor [15]
T2550 326-333 UMLS/C1707310 denotes ascade
T2545 747-755 UMLS/C0392148 denotes esence o
T2536 767-771 UMLS/C0021755 denotes 1, a
T2535 619-623 UMLS/C0021755 denotes -1 a
T2533 767-771 UMLS/C0021753 denotes 1, a
T2532 619-623 UMLS/C0021753 denotes -1 a
T2518 667-677 UMLS/C0017262 denotes pression o
T2517 271-281 UMLS/C0017262 denotes xpression
T2511 173-188 UMLS/C1267208 denotes ynovial tissue
T2506 51-61 UMLS/C0243077 denotes nhibitors
T2496 401-407 UMLS/C1552007 denotes ction
T2490 383-400 UMLS/C1515999 denotes nti-inflammatory
T2489 10-27 UMLS/C1515999 denotes nti-inflammatory
T2479 263-266 UMLS/C0005341 denotes ut
T2472 740-742 UMLS/C0319022 denotes t
T2471 425-427 UMLS/C0319022 denotes o
T2470 304-306 UMLS/C0319022 denotes o
T2442 590-599 UMLS/C0079189 denotes ytokines
T2441 42-50 UMLS/C0079189 denotes ytokine
T2440 28-37 UMLS/C0079189 denotes ytokines
T2616 537-548 UMLS/C1546706 denotes acrophages
T2615 237-247 UMLS/C1546706 denotes acrophage
T2614 132-143 UMLS/C1546706 denotes acrophages
T2605 720-735 UMLS/C0011306 denotes ndritic cells d

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T4494 738-740 TO denotes to
T4493 734-737 JJ denotes due
T4492 728-733 NN denotes cells
T4491 718-727 JJ denotes dendritic
T4490 712-717 NN denotes fluid
T4489 703-711 JJ denotes synovial
T4488 700-702 IN denotes in
T4487 690-699 VB denotes decreased
T4486 687-689 VB denotes is
T4485 679-686 NN denotes IL-10R1
T4484 676-678 IN denotes of
T4483 665-675 NN denotes expression
T4482 657-664 NN denotes surface
T4481 652-656 NN denotes Cell
T4480 649-650 -RRB- denotes ]
T4479 644-649 CD denotes 13,14
T4478 643-644 -LRB- denotes [
T4477 633-642 NN denotes complexes
T4476 626-632 JJ denotes immune
T4475 622-625 CC denotes and
T4474 617-621 NN denotes IL-1
T4473 613-616 CC denotes and
T4472 607-612 NN denotes TNF-α
T4471 604-606 IN denotes as
T4470 599-603 JJ denotes such
T4469 589-598 NN denotes cytokines
T4468 573-588 JJ denotes proinflammatory
T4467 570-572 TO denotes to
T4466 561-569 NN denotes exposure
T4465 553-560 JJ denotes chronic
T4464 548-552 IN denotes upon
T4463 536-547 NN denotes macrophages
T4462 533-535 IN denotes in
T4461 524-532 VB denotes impaired
T4460 521-523 VB denotes is
T4459 511-520 NN denotes signaling
T4458 505-510 NN denotes IL-10
T4457 491-503 NN denotes inflammation
T4456 483-490 JJ denotes chronic
T4455 476-482 IN denotes during
T4454 463-475 NN denotes transduction
T4453 456-462 NN denotes signal
T4452 453-455 IN denotes of
T4451 447-452 NN denotes level
T4450 443-446 DT denotes the
T4449 440-442 IN denotes at
T4448 430-439 VB denotes modulated
T4447 427-429 VB denotes be
T4446 424-426 TO denotes to
T4445 416-423 VB denotes appears
T4444 410-415 NN denotes IL-10
T4443 407-409 IN denotes of
T4442 400-406 NN denotes action
T4441 382-399 JJ denotes anti-inflammatory
T4440 378-381 DT denotes the
T4439 376-377 -COMMA- denotes ,
T4438 368-376 NN denotes addition
T4437 365-367 IN denotes In
T4436 362-363 -RRB- denotes ]
T4435 360-362 CD denotes 12
T4434 359-360 -LRB- denotes [
T4433 352-358 NN denotes events
T4432 336-351 JJ denotes proinflammatory
T4431 333-335 IN denotes of
T4430 325-332 NN denotes cascade
T4429 321-324 DT denotes the
T4428 306-320 VB denotes counterbalance
T4427 303-305 TO denotes to
T4426 290-302 JJ denotes insufficient
T4425 287-289 VB denotes is
T4424 281-286 NN denotes level
T4423 270-280 NN denotes expression
T4422 266-269 DT denotes the
T4421 262-265 CC denotes but
T4420 260-261 -COMMA- denotes ,
T4419 255-260 NN denotes cells
T4418 251-254 NN denotes Th1
T4417 247-250 CC denotes and
T4416 236-246 NN denotes macrophage
T4415 232-235 IN denotes for
T4414 222-231 NN denotes regulator
T4413 213-221 JJ denotes negative
T4412 211-212 DT denotes a
T4411 208-210 IN denotes as
T4410 202-207 VB denotes known
T4409 197-201 RB denotes best
T4408 194-196 VB denotes is
T4407 192-193 -COMMA- denotes ,
T4406 191-192 -RRB- denotes )
T4405 189-191 NN denotes ST
T4404 188-189 -LRB- denotes (
T4403 181-187 NN denotes tissue
T4402 172-180 JJ denotes synovial
T4401 168-171 DT denotes the
T4400 165-167 IN denotes in
T4399 159-164 NN denotes cells
T4398 157-158 NN denotes T
T4397 154-156 IN denotes by
T4396 147-153 RB denotes partly
T4395 143-146 CC denotes and
T4394 131-142 NN denotes macrophages
T4393 128-130 IN denotes by
T4392 119-127 VB denotes produced
T4391 117-118 -COMMA- denotes ,
T4390 112-117 NN denotes IL-10
T4389 104-110 NN denotes joints
T4388 101-103 NN denotes RA
T4387 98-100 IN denotes in
T4386 87-97 NN denotes quantities
T4385 81-86 JJ denotes large
T4384 78-80 IN denotes in
T4383 70-77 JJ denotes present
T4382 65-69 RB denotes also
T4381 61-64 VB denotes are
T4380 50-60 NN denotes inhibitors
T4379 41-49 NN denotes cytokine
T4378 37-40 CC denotes and
T4377 27-36 NN denotes cytokines
T4376 9-26 JJ denotes anti-inflammatory
T4375 7-8 -COMMA- denotes ,
T4374 0-7 RB denotes However
T4508 826-827 -RRB- denotes ]
T4507 824-826 CD denotes 15
T4506 823-824 -LRB- denotes [
T4505 816-822 NN denotes factor
T4504 797-815 JJ denotes colony-stimulating
T4503 774-796 JJ denotes granulocyte–macrophage
T4502 770-773 CC denotes and
T4501 768-769 -COMMA- denotes ,
T4500 764-768 NN denotes IL-1
T4499 762-763 -COMMA- denotes ,
T4498 757-762 NN denotes TNF-α
T4497 754-756 IN denotes of
T4496 745-753 NN denotes presence
T4495 741-744 DT denotes the
R1445 T4438 T4437 arg2Of addition,In
R1447 T4442 T4440 arg1Of action,the
R1448 T4442 T4441 arg1Of action,anti-inflammatory
R1449 T4442 T4443 arg1Of action,of
R1450 T4442 T4445 arg1Of action,appears
R1451 T4442 T4447 arg1Of action,be
R1452 T4442 T4448 arg2Of action,modulated
R1453 T4444 T4443 arg2Of IL-10,of
R1454 T4445 T4437 arg1Of appears,In
R1455 T4445 T4439 arg1Of appears,","
R1459 T4448 T4445 arg2Of modulated,appears
R1460 T4448 T4446 arg1Of modulated,to
R1461 T4448 T4447 arg2Of modulated,be
R1462 T4448 T4449 arg1Of modulated,at
R1463 T4448 T4455 arg1Of modulated,during
R1464 T4451 T4449 arg2Of level,at
R1465 T4451 T4450 arg1Of level,the
R1466 T4451 T4452 arg1Of level,of
R1468 T4454 T4452 arg2Of transduction,of
R1469 T4454 T4453 arg1Of transduction,signal
R1470 T4457 T4455 arg2Of inflammation,during
R1471 T4457 T4456 arg1Of inflammation,chronic
R1472 T4459 T4458 arg1Of signaling,IL-10
R1473 T4459 T4460 arg1Of signaling,is
R1474 T4459 T4461 arg2Of signaling,impaired
R1476 T4461 T4460 arg2Of impaired,is
R1477 T4461 T4462 arg1Of impaired,in
R1479 T4463 T4462 arg2Of macrophages,in
R1480 T4463 T4464 arg1Of macrophages,upon
R1481 T4466 T4464 arg2Of exposure,upon
R1482 T4466 T4465 arg1Of exposure,chronic
R1483 T4466 T4467 arg1Of exposure,to
R1485 T4469 T4468 arg1Of cytokines,proinflammatory
R1486 T4469 T4471 arg1Of cytokines,as
R1487 T4469 T4475 arg1Of cytokines,and
R1489 T4471 T4470 arg1Of as,such
R1491 T4472 T4473 arg1Of TNF-α,and
R1493 T4473 T4471 arg2Of and,as
R1494 T4474 T4473 arg2Of IL-1,and
R1495 T4475 T4467 arg2Of and,to
R1496 T4477 T4475 arg2Of complexes,and
R1497 T4477 T4476 arg1Of complexes,immune
R1498 T4477 T4478 arg1Of complexes,[
R1500 T4479 T4478 arg2Of "13,14",[
R1502 T4480 T4478 arg3Of ],[
R1504 T4483 T4481 arg1Of expression,Cell
R1505 T4483 T4482 arg1Of expression,surface
R1506 T4483 T4484 arg1Of expression,of
R1507 T4483 T4486 arg1Of expression,is
R1508 T4483 T4487 arg2Of expression,decreased
R1509 T4485 T4484 arg2Of IL-10R1,of
R1511 T4487 T4486 arg2Of decreased,is
R1512 T4487 T4488 arg1Of decreased,in
R1516 T4492 T4488 arg2Of cells,in
R1517 T4492 T4489 arg1Of cells,synovial
R1518 T4492 T4490 arg1Of cells,fluid
R1519 T4492 T4491 arg1Of cells,dendritic
R1520 T4492 T4493 arg1Of cells,due
R1521 T4493 T4494 arg1Of due,to
R1522 T4496 T4494 arg2Of presence,to
R1523 T4496 T4495 arg1Of presence,the
R1524 T4496 T4497 arg1Of presence,of
R1526 T4498 T4499 arg1Of TNF-α,","
R1527 T4499 T4502 arg1Of ",",and
R1528 T4500 T4499 arg2Of IL-1,","
R1531 T4502 T4497 arg2Of and,of
R1532 T4502 T4501 arg1Of and,","
R1533 T4505 T4502 arg2Of factor,and
R1534 T4505 T4503 arg1Of factor,granulocyte–macrophage
R1535 T4505 T4504 arg1Of factor,colony-stimulating
R1536 T4505 T4506 arg1Of factor,[
R1537 T4507 T4506 arg2Of 15,[
R1538 T4508 T4506 arg3Of ],[
R1560 T4377 T4376 arg1Of cytokines,anti-inflammatory
R1573 T4377 T4378 arg1Of cytokines,and
R1574 T4378 T4381 arg1Of and,are
R1575 T4378 T4383 arg1Of and,present
R1577 T4380 T4378 arg2Of inhibitors,and
R1581 T4380 T4379 arg1Of inhibitors,cytokine
R1582 T4381 T4374 arg1Of are,However
R1588 T4381 T4375 arg1Of are,","
R1589 T4381 T4382 arg1Of are,also
R1590 T4383 T4381 arg2Of present,are
R1599 T4383 T4384 arg1Of present,in
R1601 T4386 T4384 arg2Of quantities,in
R1608 T4386 T4385 arg1Of quantities,large
R1610 T4386 T4387 arg1Of quantities,in
R1611 T4389 T4387 arg2Of joints,in
R1618 T4389 T4388 arg1Of joints,RA
R1619 T4390 T4391 arg1Of IL-10,","
R1626 T4390 T4392 arg2Of IL-10,produced
R1627 T4390 T4408 arg1Of IL-10,is
R1633 T4390 T4410 arg2Of IL-10,known
R1635 T4392 T4393 arg1Of produced,by
R1637 T4392 T4397 arg1Of produced,by
R1638 T4393 T4395 arg1Of by,and
R1645 T4394 T4393 arg2Of macrophages,by
R1646 T4397 T4395 arg2Of by,and
R1657 T4397 T4396 arg1Of by,partly
R1660 T4399 T4397 arg2Of cells,by
R1663 T4399 T4398 arg1Of cells,T
R1664 T4399 T4400 arg1Of cells,in
R1672 T4403 T4400 arg2Of tissue,in
R1678 T4403 T4401 arg1Of tissue,the
R1681 T4403 T4402 arg1Of tissue,synovial
R1682 T4403 T4404 arg1Of tissue,(
R1685 T4405 T4404 arg2Of ST,(
R1689 T4406 T4404 arg3Of ),(
R1692 T4410 T4407 arg1Of known,","
R1698 T4410 T4408 arg2Of known,is
R1699 T4410 T4409 arg1Of known,best
R1700 T4410 T4411 arg1Of known,as
R1705 T4410 T4421 arg1Of known,but
R1709 T4414 T4411 arg2Of regulator,as
R1710 T4414 T4412 arg1Of regulator,a
R1711 T4414 T4413 arg1Of regulator,negative
R1716 T4414 T4415 arg1Of regulator,for
R1718 T4416 T4417 arg1Of macrophage,and
R1719 T4418 T4417 arg2Of Th1,and
R1728 T4419 T4415 arg2Of cells,for
R1732 T4419 T4416 arg1Of cells,macrophage
R1733 T4419 T4418 arg1Of cells,Th1
R1735 T4421 T4420 arg1Of but,","
R1743 T4424 T4422 arg1Of level,the
R1750 T4424 T4423 arg1Of level,expression
R1753 T4424 T4425 arg1Of level,is
R1755 T4424 T4426 arg1Of level,insufficient
R1756 T4424 T4428 arg1Of level,counterbalance
R1757 T4425 T4421 arg2Of is,but
R1761 T4426 T4425 arg2Of insufficient,is
R1769 T4428 T4426 arg2Of counterbalance,insufficient
R1776 T4428 T4427 arg1Of counterbalance,to
R1779 T4428 T4434 arg1Of counterbalance,[
R1780 T4430 T4428 arg2Of cascade,counterbalance
R1788 T4430 T4429 arg1Of cascade,the
R1796 T4430 T4431 arg1Of cascade,of
R1798 T4433 T4431 arg2Of events,of
R1799 T4433 T4432 arg1Of events,proinflammatory
R1800 T4435 T4434 arg2Of 12,[
R1809 T4436 T4434 arg3Of ],[

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T3506 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T3505 764-768 Protein denotes IL-1
T3504 757-762 Protein denotes TNF-α
T3503 679-686 Protein denotes IL-10R1
T3502 617-621 Protein denotes IL-1
T3501 607-612 Protein denotes TNF-α
T3500 505-510 Protein denotes IL-10
T3499 410-415 Protein denotes IL-10
T3498 112-117 Protein denotes IL-10

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T3686 505-510 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T3685 410-415 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T3684 112-117 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T3842 757-760 http://www.uniprot.org/uniprot/P01375 denotes TNF
T3841 607-610 http://www.uniprot.org/uniprot/P01375 denotes TNF
T3839 607-612 http://www.uniprot.org/uniprot/P01375 denotes TNF-α

UBERON-AE

Id Subject Object Predicate Lexical cue
T2428 703-717 http://purl.obolibrary.org/obo/UBERON_0001090 denotes synovial fluid
T2427 181-187 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

GO-BP

Id Subject Object Predicate Lexical cue
T3300 463-475 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T3290 456-475 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T3281 511-520 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T3280 456-462 http://purl.obolibrary.org/obo/GO_0023052 denotes signal
T3261 491-503 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

GO-CC

Id Subject Object Predicate Lexical cue
T3594 652-664 http://purl.obolibrary.org/obo/GO_0009986 denotes Cell surface

GO-MF

Id Subject Object Predicate Lexical cue
T3565 764-768 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T3564 617-621 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T3548 505-510 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T3547 410-415 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T3546 112-117 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10

sentences

Id Subject Object Predicate Lexical cue
T3251 652-828 Sentence denotes Cell surface expression of IL-10R1 is decreased in synovial fluid dendritic cells due to the presence of TNF-α, IL-1, and granulocyte–macrophage colony-stimulating factor [15].
T3250 505-651 Sentence denotes IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1 and immune complexes [13,14].
T3249 365-504 Sentence denotes In addition, the anti-inflammatory action of IL-10 appears to be modulated at the level of signal transduction during chronic inflammation.
T3248 112-364 Sentence denotes IL-10, produced by macrophages and partly by T cells in the synovial tissue (ST), is best known as a negative regulator for macrophage and Th1 cells, but the expression level is insufficient to counterbalance the cascade of proinflammatory events [12].
T3247 0-111 Sentence denotes However, anti-inflammatory cytokines and cytokine inhibitors are also present in large quantities in RA joints.
T24 0-111 Sentence denotes However, anti-inflammatory cytokines and cytokine inhibitors are also present in large quantities in RA joints.
T25 112-364 Sentence denotes IL-10, produced by macrophages and partly by T cells in the synovial tissue (ST), is best known as a negative regulator for macrophage and Th1 cells, but the expression level is insufficient to counterbalance the cascade of proinflammatory events [12].
T26 365-504 Sentence denotes In addition, the anti-inflammatory action of IL-10 appears to be modulated at the level of signal transduction during chronic inflammation.
T27 505-651 Sentence denotes IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1 and immune complexes [13,14].
T28 652-828 Sentence denotes Cell surface expression of IL-10R1 is decreased in synovial fluid dendritic cells due to the presence of TNF-α, IL-1, and granulocyte–macrophage colony-stimulating factor [15].

simple1

Id Subject Object Predicate Lexical cue
T3909 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T3908 764-768 Protein denotes IL-1
T3907 757-762 Protein denotes TNF-α
T3906 679-686 Protein denotes IL-10R1
T3905 617-621 Protein denotes IL-1
T3904 607-612 Protein denotes TNF-α
T3903 505-510 Protein denotes IL-10
T3902 410-415 Protein denotes IL-10
T3901 112-117 Protein denotes IL-10

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T6468 690-699 Negative_regulation denotes decreased
T6467 665-675 Gene_expression denotes expression
T6466 119-127 Gene_expression denotes produced
T6419 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T6418 764-768 Protein denotes IL-1
T6417 757-762 Protein denotes TNF-α
T6416 679-686 Protein denotes IL-10R1
T6415 617-621 Protein denotes IL-1
T6414 607-612 Protein denotes TNF-α
T6413 505-510 Protein denotes IL-10
T6412 410-415 Protein denotes IL-10
T6411 112-117 Protein denotes IL-10
R3154 T6411 T6466 themeOf IL-10,produced
R3157 T6416 T6467 themeOf IL-10R1,expression
R3189 T6467 T6468 themeOf expression,decreased

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T4908 690-699 Negative_regulation denotes decreased
T4907 665-675 Gene_expression denotes expression
T4906 119-127 Gene_expression denotes produced
T4857 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T4856 764-768 Protein denotes IL-1
T4855 757-762 Protein denotes TNF-α
T4854 679-686 Protein denotes IL-10R1
T4853 617-621 Protein denotes IL-1
T4852 607-612 Protein denotes TNF-α
T4851 505-510 Protein denotes IL-10
T4850 410-415 Protein denotes IL-10
T4849 112-117 Protein denotes IL-10
R1920 T4849 T4906 themeOf IL-10,produced
R1923 T4854 T4907 themeOf IL-10R1,expression
R1977 T4907 T4908 themeOf expression,decreased

DLUT931

Id Subject Object Predicate Lexical cue
T5923 690-699 Negative_regulation denotes decreased
T5922 665-675 Gene_expression denotes expression
T5921 430-439 Regulation denotes modulated
T5920 270-280 Gene_expression denotes expression
T5919 119-127 Gene_expression denotes produced
T5861 112-117 Protein denotes IL-10
T5866 679-686 Protein denotes IL-10R1
T5865 617-621 Protein denotes IL-1
T5864 607-612 Protein denotes TNF-α
T5863 505-510 Protein denotes IL-10
T5862 410-415 Protein denotes IL-10
T5869 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T5868 764-768 Protein denotes IL-1
T5867 757-762 Protein denotes TNF-α
R2900 T5862 T5921 themeOf IL-10,modulated
R2905 T5866 T5922 themeOf IL-10R1,expression
R2932 T5861 T5919 themeOf IL-10,produced
R2933 T5861 T5920 themeOf IL-10,expression
R2966 T5922 T5923 themeOf expression,decreased

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T6351 652-686 Gene_expression denotes Cell surface expression of IL-10R1
T6195 407-415 Protein denotes of IL-10
T6192 786-796 Entity denotes macrophage
T6189 676-686 Protein denotes of IL-10R1
T6184 101-103 Protein denotes RA
T6179 774-827 Protein denotes granulocyte–macrophage colony-stimulating factor [15]
T6163 189-191 Protein denotes ST
T6244 236-246 Entity denotes macrophage
T6242 573-606 Protein denotes proinflammatory cytokines such as
T6217 112-142 Protein denotes IL-10, produced by macrophages
T6209 652-664 Entity denotes Cell surface
T6204 378-415 Entity denotes the anti-inflammatory action of IL-10
T6281 774-796 Entity denotes granulocyte–macrophage
T6277 41-60 Protein denotes cytokine inhibitors
T6276 536-547 Entity denotes macrophages
T6271 157-193 Entity denotes T cells in the synovial tissue (ST),
T6265 505-510 Protein denotes IL-10
T6262 41-60 Entity denotes cytokine inhibitors
T6260 774-796 Entity denotes granulocyte–macrophage
T6257 626-650 Entity denotes immune complexes [13,14]
T6290 764-768 Protein denotes IL-1
T6342 505-520 Positive_regulation denotes IL-10 signaling
T6337 757-762 Protein denotes TNF-α
T6335 131-142 Entity denotes macrophages
T6332 573-612 Protein denotes proinflammatory cytokines such as TNF-α
T6319 9-36 Entity denotes anti-inflammatory cytokines
T6312 251-260 Entity denotes Th1 cells
T6308 718-827 Entity denotes dendritic cells due to the presence of TNF-α, IL-1, and granulocyte–macrophage colony-stimulating factor [15]
T6303 617-621 Protein denotes IL-1
T6302 9-36 Protein denotes anti-inflammatory cytokines
T6373 774-827 Localization denotes granulocyte–macrophage colony-stimulating factor [15]
T6368 505-621 Negative_regulation denotes IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1
T6365 112-142 Gene_expression denotes IL-10, produced by macrophages
R3102 T6179 T6373 themeOf granulocyte–macrophage colony-stimulating factor [15],granulocyte–macrophage colony-stimulating factor [15]
R3106 T6189 T6351 themeOf of IL-10R1,Cell surface expression of IL-10R1
R3109 T6217 T6365 themeOf "IL-10, produced by macrophages","IL-10, produced by macrophages"
R3114 T6260 T6373 locationOf granulocyte–macrophage,granulocyte–macrophage colony-stimulating factor [15]
R3118 T6265 T6342 causeOf IL-10,IL-10 signaling
R3141 T6342 T6368 themeOf IL-10 signaling,IL-10 signaling is impaired in macrophages upon chronic exposure to proinflammatory cytokines such as TNF-α and IL-1

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T5502 827-828 . denotes .
T5501 826-827 NNP denotes ]
T5500 824-826 CD denotes 15
T5499 823-824 NNP denotes [
T5498 816-822 NN denotes factor
T5497 797-815 JJ denotes colony-stimulating
T5496 786-796 NN denotes macrophage
T5495 774-785 NN denotes granulocyte
T5494 770-773 CC denotes and
T5493 768-769 , denotes ,
T5492 764-768 NNP denotes IL-1
T5491 762-763 , denotes ,
T5490 757-762 NNP denotes TNF-α
T5489 754-756 IN denotes of
T5488 745-753 NN denotes presence
T5487 741-744 DT denotes the
T5486 738-740 TO denotes to
T5485 734-737 JJ denotes due
T5484 728-733 NNS denotes cells
T5483 718-727 JJ denotes dendritic
T5482 712-717 NN denotes fluid
T5481 703-711 JJ denotes synovial
T5480 700-702 IN denotes in
T5479 690-699 VBN denotes decreased
T5478 687-689 VBZ denotes is
T5477 679-686 NN denotes IL-10R1
T5476 676-678 IN denotes of
T5475 665-675 NN denotes expression
T5474 657-664 NN denotes surface
T5473 652-656 NN denotes Cell
T5472 650-651 . denotes .
T5471 649-650 NNP denotes ]
T5470 644-649 CD denotes 13,14
T5469 643-644 NNP denotes [
T5468 633-642 NNS denotes complexes
T5467 626-632 JJ denotes immune
T5466 622-625 CC denotes and
T5465 617-621 NNP denotes IL-1
T5464 613-616 CC denotes and
T5463 607-612 NNP denotes TNF-α
T5462 604-606 IN denotes as
T5461 599-603 JJ denotes such
T5460 589-598 NNS denotes cytokines
T5459 573-588 JJ denotes proinflammatory
T5458 570-572 TO denotes to
T5457 561-569 NN denotes exposure
T5456 553-560 JJ denotes chronic
T5455 548-552 IN denotes upon
T5454 536-547 NNS denotes macrophages
T5453 533-535 IN denotes in
T5452 524-532 VBN denotes impaired
T5451 521-523 VBZ denotes is
T5450 511-520 VBG denotes signaling
T5449 505-510 NN denotes IL-10
T5448 503-504 . denotes .
T5447 491-503 NN denotes inflammation
T5446 483-490 JJ denotes chronic
T5445 476-482 IN denotes during
T5444 463-475 NN denotes transduction
T5443 456-462 NN denotes signal
T5442 453-455 IN denotes of
T5404 232-235 IN denotes for
T5403 222-231 NN denotes regulator
T5402 213-221 JJ denotes negative
T5401 211-212 DT denotes a
T5400 208-210 IN denotes as
T5399 202-207 VBN denotes known
T5398 197-201 RB denotes best
T5397 194-196 VBZ denotes is
T5396 192-193 , denotes ,
T5395 191-192 -RRB- denotes )
T5394 189-191 NNP denotes ST
T5393 188-189 -LRB- denotes (
T5392 181-187 NN denotes tissue
T5391 172-180 JJ denotes synovial
T5390 168-171 DT denotes the
T5389 165-167 IN denotes in
T5388 159-164 NNS denotes cells
T5387 157-158 NNP denotes T
T5386 154-156 IN denotes by
T5405 236-246 NN denotes macrophage
T5384 143-146 CC denotes and
T5383 131-142 NNS denotes macrophages
T5382 128-130 IN denotes by
T5381 119-127 VBN denotes produced
T5380 117-118 , denotes ,
T5379 112-117 NN denotes IL-10
T5378 110-111 . denotes .
T5377 104-110 NNS denotes joints
T5376 101-103 NNP denotes RA
T5375 98-100 IN denotes in
T5374 87-97 NNS denotes quantities
T5373 81-86 JJ denotes large
T5372 78-80 IN denotes in
T5371 70-77 JJ denotes present
T5370 65-69 RB denotes also
T5369 61-64 VBP denotes are
T5368 50-60 NNS denotes inhibitors
T5367 41-49 NN denotes cytokine
T5366 37-40 CC denotes and
T5365 27-36 NNS denotes cytokines
T5364 9-26 JJ denotes anti-inflammatory
T5363 7-8 , denotes ,
T5362 0-7 RB denotes However
T5385 147-153 RB denotes partly
T5441 447-452 NN denotes level
T5440 443-446 DT denotes the
T5439 440-442 IN denotes at
T5438 430-439 VBN denotes modulated
T5437 427-429 VB denotes be
T5436 424-426 TO denotes to
T5435 416-423 VBZ denotes appears
T5434 410-415 NN denotes IL-10
T5433 407-409 IN denotes of
T5432 400-406 NN denotes action
T5431 382-399 JJ denotes anti-inflammatory
T5430 378-381 DT denotes the
T5429 376-377 , denotes ,
T5428 368-376 NN denotes addition
T5427 365-367 IN denotes In
T5426 363-364 . denotes .
T5425 362-363 NNP denotes ]
T5424 360-362 CD denotes 12
T5423 359-360 NNP denotes [
T5422 352-358 NNS denotes events
T5421 336-351 JJ denotes proinflammatory
T5420 333-335 IN denotes of
T5419 325-332 NN denotes cascade
T5418 321-324 DT denotes the
T5417 306-320 VB denotes counterbalance
T5416 303-305 TO denotes to
T5415 290-302 JJ denotes insufficient
T5414 287-289 VBZ denotes is
T5413 281-286 NN denotes level
T5412 270-280 NN denotes expression
T5411 266-269 DT denotes the
T5410 262-265 CC denotes but
T5409 260-261 , denotes ,
T5408 255-260 NNS denotes cells
T5407 251-254 JJ denotes Th1
T5406 247-250 CC denotes and
R2407 T5373 T5374 amod large,quantities
R2408 T5374 T5372 pobj quantities,in
R2410 T5375 T5369 prep in,are
R2411 T5376 T5377 compound RA,joints
R2412 T5377 T5375 pobj joints,in
R2414 T5378 T5369 punct .,are
R2415 T5379 T5399 nsubjpass IL-10,known
R2416 T5380 T5379 punct ",",IL-10
R2418 T5381 T5379 acl produced,IL-10
R2419 T5382 T5381 agent by,produced
R2421 T5383 T5382 pobj macrophages,by
R2422 T5384 T5381 cc and,produced
R2423 T5385 T5386 advmod partly,by
R2424 T5386 T5399 prep by,known
R2426 T5387 T5388 compound T,cells
R2427 T5388 T5386 pobj cells,by
R2429 T5389 T5388 prep in,cells
R2430 T5390 T5392 det the,tissue
R2431 T5391 T5392 amod synovial,tissue
R2432 T5392 T5389 pobj tissue,in
R2433 T5393 T5394 punct (,ST
R2434 T5394 T5392 appos ST,tissue
R2435 T5395 T5392 punct ),tissue
R2438 T5396 T5397 punct ",",is
R2439 T5397 T5399 auxpass is,known
R2440 T5398 T5399 advmod best,known
R2442 T5399 T5399 ROOT known,known
R2443 T5400 T5399 prep as,known
R2445 T5401 T5403 det a,regulator
R2446 T5402 T5403 amod negative,regulator
R2447 T5403 T5400 pobj regulator,as
R2449 T5404 T5403 prep for,regulator
R2452 T5405 T5404 pobj macrophage,for
R2453 T5406 T5405 cc and,macrophage
R2455 T5407 T5408 amod Th1,cells
R2456 T5408 T5405 conj cells,macrophage
R2457 T5409 T5399 punct ",",known
R2459 T5410 T5399 cc but,known
R2460 T5411 T5413 det the,level
R2462 T5412 T5413 compound expression,level
R2463 T5413 T5414 nsubj level,is
R2465 T5414 T5399 conj is,known
R2467 T5415 T5414 acomp insufficient,is
R2468 T5416 T5417 aux to,counterbalance
R2469 T5417 T5415 xcomp counterbalance,insufficient
R2471 T5418 T5419 det the,cascade
R2472 T5419 T5417 dobj cascade,counterbalance
R2473 T5420 T5419 prep of,cascade
R2474 T5421 T5422 amod proinflammatory,events
R2476 T5422 T5420 pobj events,of
R2477 T5423 T5425 nmod [,]
R2479 T5424 T5425 nummod 12,]
R2480 T5425 T5419 appos ],cascade
R2481 T5426 T5414 punct .,is
R2482 T5427 T5435 prep In,appears
R2483 T5428 T5427 pobj addition,In
R2484 T5429 T5435 punct ",",appears
R2485 T5430 T5432 det the,action
R2487 T5431 T5432 amod anti-inflammatory,action
R2488 T5432 T5435 nsubj action,appears
R2489 T5433 T5432 prep of,action
R2491 T5434 T5433 pobj IL-10,of
R2492 T5435 T5435 ROOT appears,appears
R2494 T5436 T5438 aux to,modulated
R2495 T5437 T5438 auxpass be,modulated
R2496 T5438 T5435 xcomp modulated,appears
R2498 T5439 T5438 prep at,modulated
R2499 T5440 T5441 det the,level
R2500 T5441 T5439 pobj level,at
R2503 T5442 T5441 prep of,level
R2505 T5443 T5444 compound signal,transduction
R2506 T5444 T5442 pobj transduction,of
R2507 T5445 T5438 prep during,modulated
R2509 T5446 T5447 amod chronic,inflammation
R2510 T5447 T5445 pobj inflammation,during
R2511 T5448 T5435 punct .,appears
R2513 T5449 T5452 nsubjpass IL-10,impaired
R2514 T5450 T5452 nsubjpass signaling,impaired
R2515 T5451 T5452 auxpass is,impaired
R2517 T5452 T5452 ROOT impaired,impaired
R2518 T5453 T5452 prep in,impaired
R2519 T5454 T5453 pobj macrophages,in
R2521 T5455 T5452 prep upon,impaired
R2522 T5456 T5457 amod chronic,exposure
R2523 T5457 T5455 pobj exposure,upon
R2525 T5458 T5457 prep to,exposure
R2526 T5459 T5460 amod proinflammatory,cytokines
R2527 T5460 T5458 pobj cytokines,to
R2529 T5461 T5462 amod such,as
R2530 T5462 T5460 prep as,cytokines
R2531 T5463 T5468 nmod TNF-α,complexes
R2532 T5464 T5463 cc and,TNF-α
R2533 T5465 T5463 conj IL-1,TNF-α
R2534 T5466 T5465 cc and,IL-1
R2536 T5467 T5465 conj immune,IL-1
R2537 T5468 T5462 pobj complexes,as
R2538 T5469 T5471 compound [,]
R2540 T5470 T5471 compound "13,14",]
R2541 T5471 T5468 appos ],complexes
R2542 T5472 T5452 punct .,impaired
R2544 T5473 T5474 compound Cell,surface
R2545 T5474 T5475 compound surface,expression
R2547 T5475 T5479 nsubjpass expression,decreased
R2548 T5476 T5475 prep of,expression
R2549 T5477 T5476 pobj IL-10R1,of
R2550 T5478 T5479 auxpass is,decreased
R2552 T5479 T5479 ROOT decreased,decreased
R2553 T5480 T5479 prep in,decreased
R2555 T5481 T5484 amod synovial,cells
R2556 T5482 T5484 amod fluid,cells
R2557 T5483 T5484 amod dendritic,cells
R2559 T5484 T5480 pobj cells,in
R2560 T5485 T5479 conj due,decreased
R2562 T5486 T5485 pcomp to,due
R2563 T5487 T5488 det the,presence
R2564 T5488 T5485 pobj presence,due
R2566 T5489 T5488 prep of,presence
R2567 T5490 T5489 pobj TNF-α,of
R2569 T5491 T5490 punct ",",TNF-α
R2570 T5492 T5490 conj IL-1,TNF-α
R2572 T5493 T5492 punct ",",IL-1
R2574 T5494 T5492 cc and,IL-1
R2575 T5495 T5492 conj granulocyte,IL-1
R2576 T5496 T5498 nmod macrophage,factor
R2578 T5497 T5498 compound colony-stimulating,factor
R2579 T5498 T5488 appos factor,presence
R2580 T5499 T5501 nmod [,]
R2581 T5500 T5501 nummod 15,]
R2582 T5501 T5498 appos ],factor
R2584 T5502 T5479 punct .,decreased
R2392 T5362 T5369 advmod However,are
R2394 T5363 T5369 punct ",",are
R2395 T5364 T5365 amod anti-inflammatory,cytokines
R2396 T5365 T5369 nsubj cytokines,are
R2398 T5366 T5365 cc and,cytokines
R2399 T5367 T5368 compound cytokine,inhibitors
R2400 T5368 T5365 conj inhibitors,cytokines
R2402 T5369 T5369 ROOT are,are
R2403 T5370 T5369 advmod also,are
R2404 T5371 T5369 acomp present,are
R2406 T5372 T5371 prep in,present

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T3766 679-686 Protein denotes IL-10R1
T3765 617-621 Protein denotes IL-1
T3764 607-612 Protein denotes TNF-α
T3763 505-510 Protein denotes IL-10
T3762 430-439 Positive_regulation denotes modulated
T3761 410-415 Protein denotes IL-10
T3760 270-280 Gene_expression denotes expression
T3759 119-127 Gene_expression denotes produced
T3758 112-117 Protein denotes IL-10
T3770 690-699 Negative_regulation denotes decreased
T3769 665-675 Gene_expression denotes expression
T3768 764-768 Protein denotes IL-1
T3767 757-762 Protein denotes TNF-α
R981 T3758 T3759 themeOf IL-10,produced
R982 T3758 T3760 themeOf IL-10,expression
R983 T3761 T3762 themeOf IL-10,modulated
R984 T3766 T3769 themeOf IL-10R1,expression
R985 T3769 T3770 themeOf expression,decreased

test3

Id Subject Object Predicate Lexical cue
T2388 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T2387 764-768 Protein denotes IL-1
T2386 757-762 Protein denotes TNF-α
T2385 734-737 Positive_regulation denotes due
T2384 690-699 Negative_regulation denotes decreased
T2383 679-686 Protein denotes IL-10R1
T2382 665-675 Gene_expression denotes expression
T2381 617-621 Protein denotes IL-1
T2380 607-612 Protein denotes TNF-α
T2379 524-532 Negative_regulation denotes impaired
T2378 505-510 Protein denotes IL-10
T2377 410-415 Protein denotes IL-10
T2376 119-127 Gene_expression denotes produced
T2375 112-117 Protein denotes IL-10
T2301 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T2300 764-768 Protein denotes IL-1
T2299 757-762 Protein denotes TNF-α
T2298 679-686 Protein denotes IL-10R1
T2297 617-621 Protein denotes IL-1
T2296 607-612 Protein denotes TNF-α
T2295 505-510 Protein denotes IL-10
T2294 410-415 Protein denotes IL-10
T2293 112-117 Protein denotes IL-10
R804 T2375 T2376 themeOf IL-10,produced
R805 T2382 T2384 themeOf expression,decreased
R806 T2382 T2385 themeOf expression,due
R807 T2383 T2382 themeOf IL-10R1,expression
R808 T2386 T2385 causeOf TNF-α,due
R809 T2387 T2385 causeOf IL-1,due
R810 T2388 T2384 causeOf granulocyte–macrophage colony-stimulating factor,decreased
R811 T2388 T2385 causeOf granulocyte–macrophage colony-stimulating factor,due

testone

Id Subject Object Predicate Lexical cue
T2115 774-822 Protein denotes granulocyte–macrophage colony-stimulating factor
T2114 764-768 Protein denotes IL-1
T2113 757-762 Protein denotes TNF-α
T2112 679-686 Protein denotes IL-10R1
T2111 617-621 Protein denotes IL-1
T2093 607-612 Protein denotes TNF-α
T2092 505-510 Protein denotes IL-10
T2091 410-415 Protein denotes IL-10
T2090 112-117 Protein denotes IL-10
T2166 690-699 Negative_regulation denotes decreased
T2165 665-675 Gene_expression denotes expression
T2164 524-532 Negative_regulation denotes impaired
T2163 270-280 Gene_expression denotes expression
T2162 119-127 Gene_expression denotes produced
R726 T2090 T2163 themeOf IL-10,expression
R727 T2090 T2162 themeOf IL-10,produced
R728 T2093 T2164 causeOf TNF-α,impaired
R742 T2111 T2164 causeOf IL-1,impaired
R743 T2112 T2165 themeOf IL-10R1,expression
R744 T2113 T2166 causeOf TNF-α,decreased
R745 T2114 T2166 causeOf IL-1,decreased
R746 T2115 T2166 causeOf granulocyte–macrophage colony-stimulating factor,decreased
R764 T2165 T2166 themeOf expression,decreased