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PMC:1064873 / 14998-17327 JSONTXT

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LappsTest

Id Subject Object Predicate Lexical cue
T12196 1850-1854 Protein denotes IL-2
T12195 1801-1805 Protein denotes CD4+
T12194 1779-1784 Protein denotes IL-10
T12193 1683-1687 Protein denotes CD4+
T12192 1423-1428 Protein denotes IL-10
T12191 1221-1224 Protein denotes CRP
T12190 1164-1167 Protein denotes CRP
T12189 1019-1023 Protein denotes CD4+
T12188 932-937 Protein denotes IL-10
T12187 878-883 Protein denotes IL-10
T12186 785-792 Protein denotes RA CD4+
T12185 699-703 Protein denotes CD4+
T12184 483-535 Protein denotes immobilized anti-CD3 antibody and anti-CD28 antibody
T12183 381-388 Protein denotes PB CD4+
T12182 365-370 Protein denotes IL-10
T12181 346-353 Protein denotes RA CD4+
T12180 276-305 Protein denotes phosphatidylinositol 3-kinase
T12179 231-235 Protein denotes CD28
T12178 175-180 Protein denotes IL-10
T12177 74-100 Protein denotes CD28 costimulatory pathway
T12176 54-61 Protein denotes RA CD4+
T12175 14-19 Protein denotes IL-10
T12201 2299-2304 Protein denotes IL-10
T12200 2225-2232 Protein denotes RA CD4+
T12199 1998-2002 Protein denotes IL-2
T12198 1934-1939 Protein denotes IL-10
T12197 1869-1873 Protein denotes CD4+

2_test

Id Subject Object Predicate Lexical cue
15535835-10898505-4156888 307-309 10898505 denotes 24
15535835-7306232-4156889 1243-1245 7306232 denotes 26

biosemtest

Id Subject Object Predicate Lexical cue
T12795 2013-2028 UMLS/C1819447 denotes was not affect
T12794 1865-1880 UMLS/C1819447 denotes by CD4+ T cell
T12793 204-208 UMLS/C0323983 denotes his
T12792 1163-1169 UMLS/C0444497 denotes CRP l
T12791 1449-1459 UMLS/C1548180 denotes was signif
T12790 1343-1353 UMLS/C1548180 denotes without I
T12789 1012-1022 UMLS/C1548180 denotes ion by CD4
T12788 671-681 UMLS/C1548180 denotes duction by
T12787 610-620 UMLS/C1548180 denotes oduction w
T12786 41-51 UMLS/C1548180 denotes roduction
T12785 1911-1915 UMLS/C1332709 denotes ion
T12784 1053-1057 UMLS/C1332709 denotes stim
T12783 232-236 UMLS/C1332709 denotes D28
T12782 75-79 UMLS/C1332709 denotes D28
T12781 127-134 UMLS/C0003320 denotes ntigen-
T12780 2162-2170 UMLS/C2587213 denotes 13.7%;
T12779 1992-2000 UMLS/C2587213 denotes arly, IL
T12778 1644-1652 UMLS/C2587213 denotes 8 ± 7.9%
T12777 1560-1568 UMLS/C2587213 denotes ercentag
T12776 1271-1279 UMLS/C2587213 denotes There w
T12775 456-464 UMLS/C2587213 denotes ontrols
T12774 1230-1233 UMLS/C1413716 denotes <
T12773 1171-1174 UMLS/C1413716 denotes el
T12772 757-760 UMLS/C1299352 denotes as
T12771 1743-1749 UMLS/C1299351 denotes of IFN
T12770 195-203 UMLS/C1260953 denotes uppress
T12769 0-10 UMLS/C0237834 denotes Resistance
T12768 1230-1233 UMLS/C0006560 denotes <
T12767 1171-1174 UMLS/C0006560 denotes el
T12766 2051-2056 UMLS/C0439275 denotes RA pa
T12765 1788-1793 UMLS/C0439275 denotes n did
T12764 1093-1098 UMLS/C0439275 denotes L-10
T12763 967-972 UMLS/C0439275 denotes We t
T12762 876-881 UMLS/C0439275 denotes l IL-
T12761 766-771 UMLS/C0439275 denotes ml IL
T12760 528-536 UMLS/C0003241 denotes ntibody
T12759 825-836 UMLS/C1546944 denotes nificant am
T12758 1809-1815 UMLS/C0205307 denotes ells (
T12757 695-701 UMLS/C0205307 denotes mal CD
T12756 837-844 UMLS/C1265611 denotes unts of
T12755 1897-1902 UMLS/C0231290 denotes D28 c
T12754 1039-1044 UMLS/C0231290 denotes D3 an
T12753 592-597 UMLS/C0439227 denotes ours,
T12752 897-904 UMLS/C0205289 denotes mal but
T12751 2220-2227 UMLS/C1546471 denotes that RA
T12750 1478-1485 UMLS/C0439801 denotes the act
T12749 1295-1320 UMLS/C0237881 denotes ally significant differen
T12748 1911-1915 UMLS/C1426202 denotes ion
T12747 1053-1057 UMLS/C1426202 denotes stim
T12746 232-236 UMLS/C1426202 denotes D28
T12745 75-79 UMLS/C1426202 denotes D28
T12744 94-101 UMLS/C1705987 denotes athway
T12743 2033-2036 UMLS/C1518422 denotes 1
T12742 2162-2170 UMLS/C0332298 denotes 13.7%;
T12741 1992-2000 UMLS/C0332298 denotes arly, IL
T12740 1644-1652 UMLS/C0332298 denotes 8 ± 7.9%
T12739 1560-1568 UMLS/C0332298 denotes ercentag
T12738 1271-1279 UMLS/C0332298 denotes There w
T12737 456-464 UMLS/C0332298 denotes ontrols
T12736 135-143 UMLS/C1552740 denotes pecific
T12735 2069-2077 UMLS/C1705908 denotes ntage de
T12734 1968-1976 UMLS/C1705908 denotes healthy
T12733 1725-1733 UMLS/C1705908 denotes ced high
T12732 1111-1119 UMLS/C1705908 denotes s with a
T12731 409-417 UMLS/C1705908 denotes atients
T12730 1684-1695 UMLS/C0686907 denotes D4+ T cells
T12729 1542-1547 UMLS/C1705429 denotes ealth
T12728 1503-1508 UMLS/C1705429 denotes mpare
T12727 1386-1392 UMLS/C1705429 denotes g. 2a)
T12726 1542-1547 UMLS/C1705428 denotes ealth
T12725 1503-1508 UMLS/C1705428 denotes mpare
T12724 1386-1392 UMLS/C1705428 denotes g. 2a)
T12723 757-760 UMLS/C1611820 denotes as
T12722 1743-1749 UMLS/C0205250 denotes of IFN
T12721 757-760 UMLS/C0205251 denotes as
T12720 757-760 UMLS/C0234886 denotes as
T12719 2220-2227 UMLS/C0332294 denotes that RA
T12718 2220-2227 UMLS/C1274040 denotes that RA
T12717 266-273 UMLS/C0243122 denotes inding
T12716 1616-1624 UMLS/C0205254 denotes 45.6 ±
T12715 1530-1538 UMLS/C0205254 denotes group a
T12714 1809-1815 UMLS/C2347086 denotes ells (
T12713 695-701 UMLS/C2347086 denotes mal CD
T12712 739-753 UMLS/C0086045 denotes centrations as
T12711 561-575 UMLS/C0086045 denotes oncentrations
T12710 1230-1233 UMLS/C1826658 denotes <
T12709 1171-1174 UMLS/C1826658 denotes el
T12708 922-932 UMLS/C1628982 denotes bition by
T12707 20-30 UMLS/C1628982 denotes inhibition
T12706 2090-2098 UMLS/C0205216 denotes ± 13.8%)
T12705 1581-1589 UMLS/C0205216 denotes ctive RA
T12704 2079-2089 UMLS/C0439165 denotes ease, -2.1
T12703 1570-1580 UMLS/C0439165 denotes decrease:
T12702 1809-1815 UMLS/C0439166 denotes ells (
T12701 695-701 UMLS/C0439166 denotes mal CD
T12700 94-101 UMLS/C1704259 denotes athway
T12699 1542-1547 UMLS/C0439745 denotes ealth
T12698 1503-1508 UMLS/C0439745 denotes mpare
T12697 1386-1392 UMLS/C0439745 denotes g. 2a)
T12696 2162-2170 UMLS/C0243148 denotes 13.7%;
T12695 1992-2000 UMLS/C0243148 denotes arly, IL
T12694 1644-1652 UMLS/C0243148 denotes 8 ± 7.9%
T12693 1560-1568 UMLS/C0243148 denotes ercentag
T12692 1271-1279 UMLS/C0243148 denotes There w
T12691 456-464 UMLS/C0243148 denotes ontrols
T12690 182-185 UMLS/C0344312 denotes an
T12689 1230-1233 UMLS/C1879974 denotes <
T12688 1171-1174 UMLS/C1879974 denotes el
T12687 209-217 UMLS/C1706817 denotes esponse
T12686 237-261 UMLS/C1519726 denotes yrosine phosphorylation
T12685 1380-1385 UMLS/C0205449 denotes ps (F
T12684 442-447 UMLS/C0205449 denotes hree
T12683 403-408 UMLS/C0205449 denotes hree
T12682 182-185 UMLS/C0006823 denotes an
T12681 1163-1169 UMLS/C1706309 denotes CRP l
T12680 2069-2077 UMLS/C1550655 denotes ntage de
T12679 1968-1976 UMLS/C1550655 denotes healthy
T12678 1725-1733 UMLS/C1550655 denotes ced high
T12677 1111-1119 UMLS/C1550655 denotes s with a
T12676 409-417 UMLS/C1550655 denotes atients
T12675 1542-1547 UMLS/C1552839 denotes ealth
T12674 1503-1508 UMLS/C1552839 denotes mpare
T12673 1386-1392 UMLS/C1552839 denotes g. 2a)
T12672 1542-1547 UMLS/C1257890 denotes ealth
T12671 1503-1508 UMLS/C1257890 denotes mpare
T12670 1386-1392 UMLS/C1257890 denotes g. 2a)
T12669 2198-2203 UMLS/C1515187 denotes hese
T12668 2162-2170 UMLS/C1547100 denotes 13.7%;
T12667 1992-2000 UMLS/C1547100 denotes arly, IL
T12666 1644-1652 UMLS/C1547100 denotes 8 ± 7.9%
T12665 1560-1568 UMLS/C1547100 denotes ercentag
T12664 1271-1279 UMLS/C1547100 denotes There w
T12663 456-464 UMLS/C1547100 denotes ontrols
T12662 592-597 UMLS/C0564385 denotes ours,
T12661 1743-1749 UMLS/C1522410 denotes of IFN
T12660 266-273 UMLS/C1689898 denotes inding
T12659 625-633 UMLS/C0079809 denotes asured b
T12658 1478-1485 UMLS/C1549649 denotes the act
T12657 1809-1815 UMLS/C1873497 denotes ells (
T12656 695-701 UMLS/C1873497 denotes mal CD
T12655 922-932 UMLS/C0021467 denotes bition by
T12654 20-30 UMLS/C0021467 denotes inhibition
T12653 1412-1422 UMLS/C0021469 denotes effect of
T12652 922-932 UMLS/C0021469 denotes bition by
T12651 726-735 UMLS/C0021469 denotes ibited at
T12650 221-231 UMLS/C0021469 denotes nhibiting
T12649 20-30 UMLS/C0021469 denotes inhibition
T12648 1937-1945 UMLS/C0150312 denotes 10 in ac
T12647 1774-1782 UMLS/C0150312 denotes g/ml IL-
T12646 1079-1087 UMLS/C0150312 denotes e of 1 n
T12645 862-870 UMLS/C0150312 denotes ence of
T12644 1141-1149 UMLS/C0439064 denotes e inflam
T12643 1903-1906 UMLS/C2698592 denotes sti
T12642 1045-1048 UMLS/C2698592 denotes CD
T12641 528-536 UMLS/C1621287 denotes ntibody
T12640 1478-1485 UMLS/C0449295 denotes the act
T12639 1830-1833 UMLS/C0349966 denotes dit
T12638 1669-1672 UMLS/C0349966 denotes co
T12637 1394-1397 UMLS/C0349966 denotes but
T12636 656-659 UMLS/C0349966 denotes g.
T12635 1958-1964 UMLS/C1553875 denotes nts an
T12634 1715-1721 UMLS/C1553875 denotes ents p
T12633 1591-1597 UMLS/C1553875 denotes 2.9 ±
T12632 1493-1499 UMLS/C1553875 denotes roup a
T12534 470-480 UMLS/C1948023 denotes timulated
T12533 2316-2321 UMLS/C1334098 denotes activ
T12532 2057-2062 UMLS/C1334098 denotes ients
T12531 1949-1954 UMLS/C1334098 denotes RA p
T12530 1794-1799 UMLS/C1334098 denotes norma
T12529 1433-1438 UMLS/C1334098 denotes FN-γ
T12528 1362-1367 UMLS/C1334098 denotes g the
T12527 1099-1104 UMLS/C1334098 denotes n RA
T12526 936-941 UMLS/C1334098 denotes 0 was
T12525 882-887 UMLS/C1334098 denotes 0, an
T12524 772-777 UMLS/C1334098 denotes 10. H
T12523 1099-1104 UMLS/C1522550 denotes n RA
T12522 936-941 UMLS/C1522550 denotes 0 was
T12521 882-887 UMLS/C1522550 denotes 0, an
T12520 772-777 UMLS/C1522550 denotes 10. H
T12519 579-584 UMLS/C1334098 denotes L-10
T12518 366-371 UMLS/C1334098 denotes L-10,
T12517 176-181 UMLS/C1334098 denotes L-10
T12516 14-19 UMLS/C1334098 denotes IL-10
T12515 2079-2089 UMLS/C1549488 denotes ease, -2.1
T12514 1570-1580 UMLS/C1549488 denotes decrease:
T12513 1542-1547 UMLS/C1552516 denotes ealth
T12512 1503-1508 UMLS/C1552516 denotes mpare
T12511 1386-1392 UMLS/C1552516 denotes g. 2a)
T12510 2204-2212 UMLS/C1883357 denotes esults i
T12509 2162-2170 UMLS/C0009932 denotes 13.7%;
T12508 1992-2000 UMLS/C0009932 denotes arly, IL
T12507 1644-1652 UMLS/C0009932 denotes 8 ± 7.9%
T12506 1560-1568 UMLS/C0009932 denotes ercentag
T12505 1271-1279 UMLS/C0009932 denotes There w
T12504 456-464 UMLS/C0009932 denotes ontrols
T12503 2090-2098 UMLS/C0547047 denotes ± 13.8%)
T12502 1581-1589 UMLS/C0547047 denotes ctive RA
T12501 637-642 UMLS/C0014441 denotes ISA.
T12500 1743-1749 UMLS/C1561957 denotes of IFN
T12499 1743-1749 UMLS/C1561958 denotes of IFN
T12498 2069-2077 UMLS/C0030705 denotes ntage de
T12497 1968-1976 UMLS/C0030705 denotes healthy
T12496 1725-1733 UMLS/C0030705 denotes ced high
T12495 1111-1119 UMLS/C0030705 denotes s with a
T12494 409-417 UMLS/C0030705 denotes atients
T12493 1937-1945 UMLS/C0392148 denotes 10 in ac
T12492 1774-1782 UMLS/C0392148 denotes g/ml IL-
T12491 1079-1087 UMLS/C0392148 denotes e of 1 n
T12490 862-870 UMLS/C0392148 denotes ence of
T12489 373-381 UMLS/C1998793 denotes urified
T12488 1230-1233 UMLS/C0201657 denotes <
T12487 1171-1174 UMLS/C0201657 denotes el
T12486 809-813 UMLS/C1299581 denotes e to
T12485 1616-1624 UMLS/C1705605 denotes 45.6 ±
T12484 1530-1538 UMLS/C1705605 denotes group a
T12483 2037-2045 UMLS/C1314939 denotes g/ml IL-
T12482 2069-2077 UMLS/C1578479 denotes ntage de
T12481 1968-1976 UMLS/C1578479 denotes healthy
T12480 1725-1733 UMLS/C1578479 denotes ced high
T12479 1111-1119 UMLS/C1578479 denotes s with a
T12478 409-417 UMLS/C1578479 denotes atients
T12477 909-921 UMLS/C1444661 denotes complete inh
T12476 2069-2077 UMLS/C1578483 denotes ntage de
T12475 1968-1976 UMLS/C1578483 denotes healthy
T12474 1725-1733 UMLS/C1578483 denotes ced high
T12473 1111-1119 UMLS/C1578483 denotes s with a
T12472 409-417 UMLS/C1578483 denotes atients
T12471 2069-2077 UMLS/C1578480 denotes ntage de
T12470 1968-1976 UMLS/C1578480 denotes healthy
T12469 1725-1733 UMLS/C1578480 denotes ced high
T12468 1111-1119 UMLS/C1578480 denotes s with a
T12467 409-417 UMLS/C1578480 denotes atients
T12466 2069-2077 UMLS/C1578481 denotes ntage de
T12465 1968-1976 UMLS/C1578481 denotes healthy
T12464 1725-1733 UMLS/C1578481 denotes ced high
T12463 1111-1119 UMLS/C1578481 denotes s with a
T12462 409-417 UMLS/C1578481 denotes atients
T12461 1903-1906 UMLS/C0108779 denotes sti
T12460 1045-1048 UMLS/C0108779 denotes CD
T12459 2069-2077 UMLS/C1578486 denotes ntage de
T12458 1968-1976 UMLS/C1578486 denotes healthy
T12457 1725-1733 UMLS/C1578486 denotes ced high
T12456 1111-1119 UMLS/C1578486 denotes s with a
T12455 409-417 UMLS/C1578486 denotes atients
T12454 2069-2077 UMLS/C1578484 denotes ntage de
T12453 1968-1976 UMLS/C1578484 denotes healthy
T12452 1968-1976 UMLS/C1578485 denotes healthy
T12451 1725-1733 UMLS/C1578485 denotes ced high
T12450 1111-1119 UMLS/C1578485 denotes s with a
T12449 409-417 UMLS/C1578485 denotes atients
T12448 2079-2089 UMLS/C1561533 denotes ease, -2.1
T12447 1570-1580 UMLS/C1561533 denotes decrease:
T12446 1132-1139 UMLS/C0012634 denotes (multi
T12445 528-536 UMLS/C0021027 denotes ntibody
T12444 1163-1169 UMLS/C0392905 denotes CRP l
T12443 1163-1169 UMLS/C1269611 denotes CRP l
T12442 1725-1733 UMLS/C1578484 denotes ced high
T12441 1111-1119 UMLS/C1578484 denotes s with a
T12440 1958-1964 UMLS/C1561511 denotes nts an
T12439 1715-1721 UMLS/C1561511 denotes ents p
T12438 409-417 UMLS/C1578484 denotes atients
T12437 2069-2077 UMLS/C1578485 denotes ntage de
T12436 1591-1597 UMLS/C1561511 denotes 2.9 ±
T12435 1493-1499 UMLS/C1561511 denotes roup a
T12434 1125-1131 UMLS/C1561513 denotes diseas
T12433 423-429 UMLS/C1561513 denotes ctive
T12432 2228-2236 UMLS/C1444656 denotes CD4+ T c
T12431 757-760 UMLS/C0441994 denotes as
T12430 209-217 UMLS/C1704632 denotes esponse
T12429 837-844 UMLS/C1561574 denotes unts of
T12428 266-273 UMLS/C1167622 denotes inding
T12427 757-760 UMLS/C1708760 denotes as
T12426 186-194 UMLS/C1947931 denotes irectly
T12425 1542-1547 UMLS/C1561557 denotes ealth
T12424 1503-1508 UMLS/C1561557 denotes mpare
T12423 1386-1392 UMLS/C1561557 denotes g. 2a)
T12422 1958-1964 UMLS/C0205177 denotes nts an
T12421 1715-1721 UMLS/C0205177 denotes ents p
T12420 1591-1597 UMLS/C0205177 denotes 2.9 ±
T12419 1493-1499 UMLS/C0205177 denotes roup a
T12418 1125-1131 UMLS/C0205177 denotes diseas
T12417 423-429 UMLS/C0205177 denotes ctive
T12416 1616-1624 UMLS/C1608264 denotes 45.6 ±
T12415 1530-1538 UMLS/C1608264 denotes group a
T12414 757-760 UMLS/C1619811 denotes as
T12413 1616-1624 UMLS/C1608263 denotes 45.6 ±
T12412 1530-1538 UMLS/C1608263 denotes group a
T12411 1478-1485 UMLS/C0205189 denotes the act
T12410 1230-1233 UMLS/C1413766 denotes <
T12409 1171-1174 UMLS/C1413766 denotes el
T12408 0-10 UMLS/C0683598 denotes Resistance
T12407 1958-1964 UMLS/C2347179 denotes nts an
T12406 1715-1721 UMLS/C2347179 denotes ents p
T12405 1591-1597 UMLS/C2347179 denotes 2.9 ±
T12404 1493-1499 UMLS/C2347179 denotes roup a
T12403 1125-1131 UMLS/C2347179 denotes diseas
T12402 423-429 UMLS/C2347179 denotes ctive
T12401 2316-2321 UMLS/C0085295 denotes activ
T12400 2057-2062 UMLS/C0085295 denotes ients
T12399 1949-1954 UMLS/C0085295 denotes RA p
T12398 1794-1799 UMLS/C0085295 denotes norma
T12397 1433-1438 UMLS/C0085295 denotes FN-γ
T12396 1362-1367 UMLS/C0085295 denotes g the
T12395 1099-1104 UMLS/C0085295 denotes n RA
T12394 936-941 UMLS/C0085295 denotes 0 was
T12393 882-887 UMLS/C0085295 denotes 0, an
T12392 772-777 UMLS/C0085295 denotes 10. H
T12391 579-584 UMLS/C0085295 denotes L-10
T12390 366-371 UMLS/C0085295 denotes L-10,
T12389 176-181 UMLS/C0085295 denotes L-10
T12388 14-19 UMLS/C0085295 denotes IL-10
T12387 757-760 UMLS/C1548802 denotes as
T12386 277-306 UMLS/C0044602 denotes hosphatidylinositol 3-kinase
T12385 2143-2150 UMLS/C0392756 denotes hy cont
T12384 2090-2098 UMLS/C0392756 denotes ± 13.8%)
T12383 1581-1589 UMLS/C0392756 denotes ctive RA
T12382 1809-1815 UMLS/C1704701 denotes ells (
T12381 695-701 UMLS/C1704701 denotes mal CD
T12380 1404-1407 UMLS/C0005341 denotes hib
T12379 905-908 UMLS/C0005341 denotes not
T12378 2282-2284 UMLS/C0319022 denotes la
T12377 814-816 UMLS/C0319022 denotes pr
T12376 363-365 UMLS/C0319022 denotes o
T12375 313-315 UMLS/C0319022 denotes o
T12374 11-13 UMLS/C0319022 denotes to
T12373 553-560 UMLS/C1720119 denotes iluted
T12372 1542-1547 UMLS/C1522242 denotes ealth
T12371 1503-1508 UMLS/C1522242 denotes mpare
T12370 1386-1392 UMLS/C1522242 denotes g. 2a)
T12369 625-633 UMLS/C0444706 denotes asured b
T12368 2037-2045 UMLS/C0392760 denotes g/ml IL-
T12367 1809-1815 UMLS/C1550457 denotes ells (
T12366 695-701 UMLS/C1550457 denotes mal CD
T12365 1125-1131 UMLS/C1561511 denotes diseas
T12364 1835-1837 UMLS/C1553634 denotes n,
T12363 423-429 UMLS/C1561511 denotes ctive
T12362 1958-1964 UMLS/C1561512 denotes nts an
T12361 1715-1721 UMLS/C1561512 denotes ents p
T12360 1591-1597 UMLS/C1561512 denotes 2.9 ±
T12359 1493-1499 UMLS/C1561512 denotes roup a
T12358 1125-1131 UMLS/C1561512 denotes diseas
T12357 423-429 UMLS/C1561512 denotes ctive
T12356 1399-1401 UMLS/C1553634 denotes he
T12355 1958-1964 UMLS/C1561510 denotes nts an
T12354 1958-1964 UMLS/C1561513 denotes nts an
T12353 1715-1721 UMLS/C1561513 denotes ents p
T12352 1591-1597 UMLS/C1561513 denotes 2.9 ±
T12351 1493-1499 UMLS/C1561513 denotes roup a
T12350 1715-1721 UMLS/C1561510 denotes ents p
T12349 1591-1597 UMLS/C1561510 denotes 2.9 ±
T12348 1493-1499 UMLS/C1561510 denotes roup a
T12347 1125-1131 UMLS/C1561510 denotes diseas
T12346 423-429 UMLS/C1561510 denotes ctive
T12345 1958-1964 UMLS/C1561509 denotes nts an
T12344 1715-1721 UMLS/C1561509 denotes ents p
T12343 1591-1597 UMLS/C1561509 denotes 2.9 ±
T12342 1493-1499 UMLS/C1561509 denotes roup a
T12341 1125-1131 UMLS/C1561509 denotes diseas
T12340 423-429 UMLS/C1561509 denotes ctive
T12339 1958-1964 UMLS/C1561508 denotes nts an
T12338 1715-1721 UMLS/C1561508 denotes ents p
T12337 1591-1597 UMLS/C1561508 denotes 2.9 ±
T12336 1493-1499 UMLS/C1561508 denotes roup a
T12335 1125-1131 UMLS/C1561508 denotes diseas
T12334 423-429 UMLS/C1561508 denotes ctive
T12333 1150-1162 UMLS/C0333348 denotes atory joints
T12332 1958-1964 UMLS/C1561507 denotes nts an
T12331 1715-1721 UMLS/C1561507 denotes ents p
T12330 1591-1597 UMLS/C1561507 denotes 2.9 ±
T12329 1493-1499 UMLS/C1561507 denotes roup a
T12328 1125-1131 UMLS/C1561507 denotes diseas
T12327 423-429 UMLS/C1561507 denotes ctive
T12326 825-836 UMLS/C0750502 denotes nificant am
T12325 144-170 UMLS/C1817749 denotes -cell cytokine production,
T12324 266-273 UMLS/C1145667 denotes inding
T12323 1809-1815 UMLS/C1551394 denotes ells (
T12322 695-701 UMLS/C1551394 denotes mal CD
T12321 1478-1485 UMLS/C2349209 denotes the act
T12320 266-273 UMLS/C2349209 denotes inding
T12319 1958-1964 UMLS/C1547419 denotes nts an
T12631 1125-1131 UMLS/C1553875 denotes diseas
T12630 423-429 UMLS/C1553875 denotes ctive
T12629 2090-2098 UMLS/C0442797 denotes ± 13.8%)
T12628 1581-1589 UMLS/C0442797 denotes ctive RA
T12627 1843-1851 UMLS/C1883712 denotes mpared I
T12626 2250-2257 UMLS/C0039194 denotes ss susc
T12625 1889-1896 UMLS/C0039194 denotes D3 and
T12624 1821-1828 UMLS/C0039194 denotes a). In
T12623 1702-1709 UMLS/C0039194 denotes ctive R
T12622 1031-1038 UMLS/C0039194 denotes after
T12621 796-803 UMLS/C0039194 denotes ells we
T12620 707-714 UMLS/C0039194 denotes ells wa
T12619 390-397 UMLS/C0039194 denotes cells
T12618 355-362 UMLS/C0039194 denotes cells
T12617 63-70 UMLS/C0039194 denotes cells
T12616 1207-1228 UMLS/C0544452 denotes in remission, CRP lev
T12615 1198-1214 UMLS/C0544452 denotes disease (in remi
T12614 135-143 UMLS/C0205369 denotes pecific
T12613 2198-2203 UMLS/C1883727 denotes hese
T12612 1750-1756 UMLS/C0456079 denotes γ in t
T12611 1234-1239 UMLS/C0456079 denotes 0 mg/
T12610 1175-1180 UMLS/C0456079 denotes 10 m
T12609 995-1001 UMLS/C0456079 denotes of IF
T12608 117-126 UMLS/C1704419 denotes ffective
T12607 1911-1915 UMLS/C0075747 denotes ion
T12606 1053-1057 UMLS/C0075747 denotes stim
T12605 232-236 UMLS/C0075747 denotes D28
T12604 75-79 UMLS/C0075747 denotes D28
T12603 1163-1169 UMLS/C0022417 denotes CRP l
T12602 1856-1864 UMLS/C1707455 denotes roductio
T12601 1512-1520 UMLS/C1707455 denotes th the i
T12600 982-990 UMLS/C1707455 denotes ed the l
T12599 1321-1332 UMLS/C1705242 denotes es in IFN-γ
T12598 2162-2170 UMLS/C1550141 denotes 13.7%;
T12597 1992-2000 UMLS/C1550141 denotes arly, IL
T12596 1644-1652 UMLS/C1550141 denotes 8 ± 7.9%
T12595 1560-1568 UMLS/C1550141 denotes ercentag
T12594 1271-1279 UMLS/C1550141 denotes There w
T12593 456-464 UMLS/C1550141 denotes ontrols
T12592 739-753 UMLS/C1446561 denotes centrations as
T12591 561-575 UMLS/C1446561 denotes oncentrations
T12590 1321-1332 UMLS/C1705241 denotes es in IFN-γ
T12589 2316-2321 UMLS/C1149215 denotes activ
T12588 2057-2062 UMLS/C1149215 denotes ients
T12587 1949-1954 UMLS/C1149215 denotes RA p
T12586 1794-1799 UMLS/C1149215 denotes norma
T12585 1433-1438 UMLS/C1149215 denotes FN-γ
T12584 1362-1367 UMLS/C1149215 denotes g the
T12583 1099-1104 UMLS/C1149215 denotes n RA
T12582 936-941 UMLS/C1149215 denotes 0 was
T12581 882-887 UMLS/C1149215 denotes 0, an
T12580 772-777 UMLS/C1149215 denotes 10. H
T12579 579-584 UMLS/C1149215 denotes L-10
T12578 366-371 UMLS/C1149215 denotes L-10,
T12577 176-181 UMLS/C1149215 denotes L-10
T12576 14-19 UMLS/C1149215 denotes IL-10
T12575 1835-1837 UMLS/C0450353 denotes n,
T12574 1399-1401 UMLS/C0450353 denotes he
T12573 1674-1676 UMLS/C0450354 denotes eq
T12572 496-513 UMLS/C0879551 denotes nti-CD3 antibody
T12571 1750-1756 UMLS/C0441889 denotes γ in t
T12570 1234-1239 UMLS/C0441889 denotes 0 mg/
T12569 1175-1180 UMLS/C0441889 denotes 10 m
T12568 995-1001 UMLS/C0441889 denotes of IF
T12567 625-633 UMLS/C1879489 denotes asured b
T12566 0-10 UMLS/C1522618 denotes Resistance
T12565 316-324 UMLS/C0220825 denotes valuate
T12564 946-954 UMLS/C1706701 denotes ined at
T12563 2306-2312 UMLS/C2348382 denotes uring
T12562 1423-1429 UMLS/C2348382 denotes IL-10
T12561 757-760 UMLS/C1550472 denotes as
T12560 2270-2281 UMLS/C0231204 denotes e immunoreg
T12559 1542-1547 UMLS/C0441833 denotes ealth
T12558 1503-1508 UMLS/C0441833 denotes mpare
T12557 1386-1392 UMLS/C0441833 denotes g. 2a)
T12556 685-694 UMLS/C1879547 denotes ivated no
T12555 2220-2227 UMLS/C1280519 denotes that RA
T12554 809-813 UMLS/C0085732 denotes e to
T12553 946-954 UMLS/C1301820 denotes ined at
T12552 2306-2312 UMLS/C1280500 denotes uring
T12551 1423-1429 UMLS/C1280500 denotes IL-10
T12550 625-633 UMLS/C0242485 denotes asured b
T12549 1478-1485 UMLS/C1549479 denotes the act
T12548 553-560 UMLS/C1948037 denotes iluted
T12547 2037-2045 UMLS/C0001721 denotes g/ml IL-
T12546 1897-1902 UMLS/C0687676 denotes D28 c
T12545 1039-1044 UMLS/C0687676 denotes D3 an
T12544 2316-2321 UMLS/C1522550 denotes activ
T12543 2057-2062 UMLS/C1522550 denotes ients
T12542 1949-1954 UMLS/C1522550 denotes RA p
T12541 1794-1799 UMLS/C1522550 denotes norma
T12540 1433-1438 UMLS/C1522550 denotes FN-γ
T12539 1362-1367 UMLS/C1522550 denotes g the
T12538 579-584 UMLS/C1522550 denotes L-10
T12537 366-371 UMLS/C1522550 denotes L-10,
T12536 176-181 UMLS/C1522550 denotes L-10
T12535 14-19 UMLS/C1522550 denotes IL-10
T12318 1715-1721 UMLS/C1547419 denotes ents p
T12317 1591-1597 UMLS/C1547419 denotes 2.9 ±
T12316 1493-1499 UMLS/C1547419 denotes roup a
T12315 1125-1131 UMLS/C1547419 denotes diseas
T12314 423-429 UMLS/C1547419 denotes ctive
T12313 1616-1624 UMLS/C1547420 denotes 45.6 ±
T12312 1530-1538 UMLS/C1547420 denotes group a
T12311 209-217 UMLS/C0871261 denotes esponse
T12310 2162-2170 UMLS/C1882979 denotes 13.7%;
T12309 1992-2000 UMLS/C1882979 denotes arly, IL
T12308 1644-1652 UMLS/C1882979 denotes 8 ± 7.9%
T12307 1560-1568 UMLS/C1882979 denotes ercentag
T12306 1271-1279 UMLS/C1882979 denotes There w
T12305 456-464 UMLS/C1882979 denotes ontrols

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T13584 2323-2328 NN denotes phase
T13583 2316-2322 JJ denotes active
T13582 2312-2315 DT denotes the
T13581 2305-2311 IN denotes during
T13580 2299-2304 NN denotes IL-10
T13579 2296-2298 IN denotes of
T13578 2289-2295 NN denotes effect
T13577 2272-2288 JJ denotes immunoregulatory
T13576 2268-2271 DT denotes the
T13575 2265-2267 TO denotes to
T13574 2253-2264 JJ denotes susceptible
T13573 2248-2252 RB denotes less
T13572 2241-2247 VB denotes become
T13571 2235-2240 NN denotes cells
T13570 2233-2234 NN denotes T
T13569 2228-2232 JJ denotes CD4+
T13568 2225-2227 NN denotes RA
T13567 2220-2224 IN denotes that
T13566 2211-2219 VB denotes indicate
T13565 2203-2210 NN denotes results
T13564 2197-2202 DT denotes these
T13563 2195-2196 -COMMA- denotes ,
T13562 2187-2195 RB denotes together
T13561 2181-2186 VB denotes Taken
T13560 2178-2179 -RRB- denotes )
T13559 2174-2178 CD denotes 0.05
T13558 2172-2173 SYM denotes <
T13557 2170-2171 NN denotes P
T13556 2168-2169 -COLON- denotes ;
T13555 2167-2168 NN denotes %
T13554 2163-2167 CD denotes 13.7
T13553 2161-2162 SYM denotes ±
T13552 2156-2160 CD denotes 61.1
T13551 2155-2156 -LRB- denotes (
T13550 2146-2154 NN denotes controls
T13549 2138-2145 JJ denotes healthy
T13548 2135-2137 IN denotes in
T13547 2127-2134 VB denotes reduced
T13546 2113-2126 RB denotes significantly
T13545 2109-2112 VB denotes was
T13544 2106-2108 PRP denotes it
T13543 2100-2105 IN denotes while
T13542 2098-2099 -COMMA- denotes ,
T13541 2097-2098 -RRB- denotes )
T13540 2096-2097 NN denotes %
T13539 2092-2096 CD denotes 13.8
T13538 2090-2091 -COLON- denotes ±
T13537 2085-2089 CD denotes -2.1
T13536 2083-2084 -COMMA- denotes ,
T13535 2075-2083 NN denotes decrease
T13534 2064-2074 NN denotes percentage
T13533 2063-2064 -LRB- denotes (
T13532 2054-2062 NN denotes patients
T13531 2051-2053 NN denotes RA
T13530 2048-2050 IN denotes in
T13529 2042-2047 NN denotes IL-10
T13528 2036-2041 NN denotes ng/ml
T13527 2034-2035 CD denotes 1
T13526 2031-2033 IN denotes by
T13525 2022-2030 VB denotes affected
T13524 2018-2021 RB denotes not
T13523 2014-2017 VB denotes was
T13522 2003-2013 NN denotes production
T13521 1998-2002 NN denotes IL-2
T13520 1996-1997 -COMMA- denotes ,
T13519 1987-1996 RB denotes Similarly
T13518 1977-1985 NN denotes controls
T13517 1969-1976 JJ denotes healthy
T13516 1966-1968 IN denotes in
T13515 1962-1965 CC denotes and
T13514 1953-1961 NN denotes patients
T13513 1950-1952 NN denotes RA
T13512 1943-1949 JJ denotes active
T13511 1940-1942 IN denotes in
T13510 1934-1939 NN denotes IL-10
T13509 1931-1933 IN denotes of
T13508 1922-1930 NN denotes presence
T13507 1918-1921 DT denotes the
T13506 1915-1917 IN denotes in
T13505 1901-1914 NN denotes costimulation
T13504 1896-1900 NN denotes CD28
T13503 1892-1895 CC denotes and
T13502 1888-1891 NN denotes CD3
T13501 1882-1887 IN denotes after
T13500 1876-1881 NN denotes cells
T13499 1874-1875 NN denotes T
T13498 1869-1873 JJ denotes CD4+
T13432 1589-1590 -COMMA- denotes ,
T13431 1587-1589 NN denotes RA
T13430 1580-1586 JJ denotes active
T13429 1578-1579 -COLON- denotes :
T13428 1570-1578 NN denotes decrease
T13427 1559-1569 NN denotes percentage
T13426 1558-1559 -LRB- denotes (
T13425 1549-1557 NN denotes controls
T13424 1541-1548 JJ denotes healthy
T13423 1537-1540 CC denotes and
T13422 1531-1536 NN denotes group
T13421 1528-1530 NN denotes RA
T13420 1519-1527 JJ denotes inactive
T13419 1515-1518 DT denotes the
T13418 1510-1514 IN denotes with
T13417 1501-1509 VB denotes compared
T13416 1498-1500 IN denotes as
T13415 1492-1497 NN denotes group
T13414 1489-1491 NN denotes RA
T13413 1482-1488 JJ denotes active
T13412 1478-1481 DT denotes the
T13411 1475-1477 IN denotes in
T13410 1467-1474 VB denotes limited
T13409 1453-1466 RB denotes significantly
T13408 1449-1452 VB denotes was
T13407 1438-1448 NN denotes production
T13406 1432-1437 NN denotes IFN-γ
T13405 1429-1431 IN denotes on
T13404 1423-1428 NN denotes IL-10
T13403 1420-1422 IN denotes of
T13402 1413-1419 NN denotes effect
T13401 1402-1412 JJ denotes inhibitory
T13400 1398-1401 DT denotes the
T13399 1394-1397 CC denotes but
T13398 1392-1393 -COMMA- denotes ,
T13397 1391-1392 -RRB- denotes )
T13396 1389-1391 NN denotes 2a
T13395 1384-1388 NNP denotes Fig.
T13394 1383-1384 -LRB- denotes (
T13393 1376-1382 NN denotes groups
T13392 1370-1375 CD denotes three
T13391 1364-1369 DT denotes these
T13390 1358-1363 IN denotes among
T13389 1352-1357 NN denotes IL-10
T13388 1344-1351 IN denotes without
T13387 1333-1343 NN denotes production
T13386 1327-1332 NN denotes IFN-γ
T13385 1324-1326 IN denotes in
T13384 1312-1323 NN denotes differences
T13383 1300-1311 JJ denotes significant
T13382 1286-1299 RB denotes statistically
T13381 1283-1285 DT denotes no
T13380 1278-1282 VB denotes were
T13379 1272-1277 EX denotes There
T13378 1262-1270 NN denotes controls
T13377 1254-1261 JJ denotes healthy
T13376 1251-1253 IN denotes in
T13375 1247-1250 CC denotes and
T13374 1245-1246 -RRB- denotes ]
T13373 1243-1245 CD denotes 26
T13372 1242-1243 -LRB- denotes [
T13371 1240-1241 -RRB- denotes )
T13370 1236-1240 NN denotes mg/l
T13369 1233-1235 CD denotes 10
T13368 1231-1232 SYM denotes <
T13367 1225-1230 NN denotes level
T13366 1221-1224 NN denotes CRP
T13365 1219-1220 -COMMA- denotes ,
T13364 1210-1219 NN denotes remission
T13363 1207-1209 IN denotes in
T13362 1206-1207 -LRB- denotes (
T13361 1198-1205 NN denotes disease
T13360 1189-1197 JJ denotes inactive
T13359 1185-1188 CC denotes and
T13358 1183-1184 -RRB- denotes )
T13357 1179-1183 NN denotes mg/l
T13356 1176-1178 CD denotes 10
T13355 1174-1175 NN denotes ≥
T13354 1168-1173 NN denotes level
T13353 1164-1167 NN denotes CRP
T13352 1162-1163 -COMMA- denotes ,
T13351 1156-1162 NN denotes joints
T13350 1143-1155 JJ denotes inflammatory
T13349 1134-1142 JJ denotes multiple
T13348 1133-1134 -LRB- denotes (
T13347 1125-1132 NN denotes disease
T13346 1118-1124 JJ denotes active
T13345 1113-1117 IN denotes with
T13344 1104-1112 NN denotes patients
T13343 1101-1103 NN denotes RA
T13342 1098-1100 IN denotes in
T13341 1092-1097 NN denotes IL-10
T13340 1086-1091 NN denotes ng/ml
T13339 1084-1085 CD denotes 1
T13338 1081-1083 IN denotes of
T13337 1072-1080 NN denotes presence
T13336 1068-1071 DT denotes the
T13335 1065-1067 IN denotes in
T13334 1051-1064 NN denotes costimulation
T13333 1046-1050 NN denotes CD28
T13332 1042-1045 CC denotes and
T13331 1038-1041 NN denotes CD3
T13330 1032-1037 IN denotes after
T13329 1026-1031 NN denotes cells
T13328 1024-1025 NN denotes T
T13327 1019-1023 JJ denotes CD4+
T13326 1016-1018 IN denotes by
T13325 1005-1015 NN denotes production
T13324 999-1004 NN denotes IFN-γ
T13323 996-998 IN denotes of
T13322 989-995 NN denotes levels
T13321 985-988 DT denotes the
T13320 976-984 VB denotes compared
T13319 971-975 RB denotes thus
T13318 968-970 PRP denotes We
T13317 961-966 NN denotes ng/ml
T13316 954-960 CD denotes 10–100
T13315 951-953 IN denotes at
T13314 942-950 VB denotes obtained
T13313 938-941 VB denotes was
T13312 932-937 NN denotes IL-10
T13311 929-931 IN denotes by
T13310 918-928 NN denotes inhibition
T13309 909-917 JJ denotes complete
T13308 905-908 RB denotes not
T13307 901-904 CC denotes but
T13306 893-900 JJ denotes maximal
T13305 889-892 DT denotes the
T13304 885-888 CC denotes and
T13303 883-884 -COMMA- denotes ,
T13302 878-883 NN denotes IL-10
T13301 872-877 NN denotes ng/ml
T13300 870-871 CD denotes 1
T13299 867-869 IN denotes of
T13298 858-866 NN denotes presence
T13297 854-857 DT denotes the
T13296 851-853 IN denotes in
T13295 845-850 NN denotes IFN-γ
T13294 842-844 IN denotes of
T13293 834-841 NN denotes amounts
T13292 822-833 JJ denotes significant
T13291 814-821 VB denotes produce
T13290 811-813 TO denotes to
T13289 806-810 JJ denotes able
T13288 801-805 VB denotes were
T13287 795-800 NN denotes cells
T13286 793-794 NN denotes T
T13285 788-792 JJ denotes CD4+
T13284 785-787 NN denotes RA
T13283 783-784 -COMMA- denotes ,
T13282 776-783 RB denotes However
T13281 769-774 NN denotes IL-10
T13280 763-768 NN denotes ng/ml
T13279 761-762 CD denotes 1
T13278 758-760 IN denotes as
T13277 754-757 JJ denotes low
T13276 751-753 RB denotes as
T13275 736-750 NN denotes concentrations
T13274 733-735 IN denotes at
T13273 723-732 VB denotes inhibited
T13272 716-722 RB denotes mostly
T13271 712-715 VB denotes was
T13270 706-711 NN denotes cells
T13269 704-705 NN denotes T
T13268 699-703 JJ denotes CD4+
T13267 692-698 JJ denotes normal
T13266 682-691 VB denotes activated
T13265 679-681 IN denotes by
T13264 668-678 NN denotes production
T13263 662-667 NN denotes IFN-γ
T13262 660-661 -COMMA- denotes ,
T13261 659-660 CD denotes 1
T13260 654-658 NNP denotes Fig.
T13259 651-653 IN denotes in
T13258 645-650 VB denotes shown
T13257 642-644 IN denotes As
T13256 635-640 NN denotes ELISA
T13255 632-634 IN denotes by
T13254 623-631 VB denotes measured
T13253 619-622 VB denotes was
T13252 608-618 NN denotes production
T13251 602-607 NN denotes IFN-γ
T13250 598-601 CC denotes and
T13249 596-597 -COMMA- denotes ,
T13248 591-596 NN denotes hours
T13247 588-590 CD denotes 36
T13246 584-587 IN denotes for
T13245 578-583 NN denotes IL-10
T13244 575-577 IN denotes of
T13243 560-574 NN denotes concentrations
T13242 552-559 JJ denotes diluted
T13241 544-551 IN denotes without
T13240 541-543 CC denotes or
T13239 536-540 IN denotes with
T13238 527-535 NN denotes antibody
T13237 517-526 JJ denotes anti-CD28
T13236 513-516 CC denotes and
T13235 504-512 NN denotes antibody
T13234 495-503 JJ denotes anti-CD3
T13233 483-494 VB denotes immobilized
T13232 480-482 IN denotes by
T13231 469-479 VB denotes stimulated
T13230 464-468 VB denotes were
T13229 455-463 NN denotes controls
T13228 447-454 JJ denotes healthy
T13227 441-446 CD denotes three
T13226 436-440 IN denotes from
T13225 432-435 CC denotes and
T13224 429-431 NN denotes RA
T13223 422-428 JJ denotes active
T13222 417-421 IN denotes with
T13221 408-416 NN denotes patients
T13220 402-407 CD denotes three
T13219 397-401 IN denotes from
T13218 391-396 NN denotes cells
T13217 389-390 NN denotes T
T13497 1866-1868 IN denotes by
T13496 1855-1865 NN denotes production
T13495 1850-1854 NN denotes IL-2
T13494 1841-1849 VB denotes compared
T13493 1838-1840 PRP denotes we
T13492 1836-1837 -COMMA- denotes ,
T13491 1828-1836 NN denotes addition
T13490 1825-1827 IN denotes In
T13489 1822-1823 -RRB- denotes )
T13488 1820-1822 NN denotes 2a
T13487 1815-1819 NN denotes Fig.
T13486 1814-1815 -LRB- denotes (
T13485 1808-1813 NN denotes cells
T13484 1806-1807 NN denotes T
T13483 1801-1805 JJ denotes CD4+
T13482 1794-1800 JJ denotes normal
T13481 1790-1793 VB denotes did
T13480 1785-1789 IN denotes than
T13479 1779-1784 NN denotes IL-10
T13478 1773-1778 NN denotes ng/ml
T13477 1771-1772 CD denotes 1
T13476 1768-1770 IN denotes of
T13475 1759-1767 NN denotes presence
T13474 1755-1758 DT denotes the
T13473 1752-1754 IN denotes in
T13472 1746-1751 NN denotes IFN-γ
T13471 1743-1745 IN denotes of
T13470 1736-1742 NN denotes levels
T13469 1729-1735 JJ denotes higher
T13468 1720-1728 VB denotes produced
T13467 1711-1719 NN denotes patients
T13466 1708-1710 NN denotes RA
T13465 1701-1707 JJ denotes active
T13464 1696-1700 IN denotes from
T13463 1690-1695 NN denotes cells
T13462 1688-1689 NN denotes T
T13461 1683-1687 JJ denotes CD4+
T13460 1681-1682 -COMMA- denotes ,
T13459 1670-1681 NN denotes consequence
T13458 1668-1669 DT denotes a
T13457 1665-1667 IN denotes As
T13456 1662-1663 -RRB- denotes )
T13455 1660-1662 NN denotes 2b
T13454 1655-1659 NNP denotes Fig.
T13453 1654-1655 -LRB- denotes (
T13452 1652-1653 -RRB- denotes )
T13451 1651-1652 NN denotes %
T13450 1648-1651 CD denotes 7.9
T13449 1646-1647 -COLON- denotes ±
T13448 1641-1645 CD denotes 65.8
T13447 1639-1640 -COMMA- denotes ,
T13446 1631-1639 NN denotes controls
T13445 1629-1630 -COLON- denotes ;
T13444 1628-1629 NN denotes %
T13443 1624-1628 CD denotes 14.4
T13442 1622-1623 CC denotes ±
T13441 1617-1621 CD denotes 45.6
T13440 1615-1616 -COMMA- denotes ,
T13439 1613-1615 NN denotes RA
T13438 1604-1612 JJ denotes inactive
T13437 1602-1603 -COLON- denotes ;
T13436 1601-1602 NN denotes %
T13435 1597-1601 CD denotes 14.4
T13434 1595-1596 CC denotes ±
T13433 1591-1594 CD denotes 2.9
T13216 384-388 JJ denotes CD4+
T13215 381-383 NN denotes PB
T13214 372-380 VB denotes purified
T13213 370-371 -COMMA- denotes ,
T13212 365-370 NN denotes IL-10
T13211 362-364 TO denotes to
T13210 356-361 NN denotes cells
T13209 354-355 NN denotes T
T13208 349-353 JJ denotes CD4+
T13207 346-348 NN denotes RA
T13206 343-345 IN denotes of
T13205 328-342 NN denotes responsiveness
T13204 324-327 DT denotes the
T13203 315-323 VB denotes evaluate
T13202 312-314 TO denotes To
T13201 309-310 -RRB- denotes ]
T13200 307-309 CD denotes 24
T13199 306-307 -LRB- denotes [
T13198 297-305 NN denotes 3-kinase
T13197 276-296 NN denotes phosphatidylinositol
T13196 273-275 IN denotes of
T13195 265-272 NN denotes binding
T13194 261-264 CC denotes and
T13193 245-260 NN denotes phosphorylation
T13192 236-244 NN denotes tyrosine
T13191 231-235 NN denotes CD28
T13190 220-230 VB denotes inhibiting
T13189 217-219 IN denotes by
T13188 208-216 NN denotes response
T13187 203-207 DT denotes this
T13186 194-202 VB denotes suppress
T13185 185-193 RB denotes directly
T13184 181-184 MD denotes can
T13183 175-180 NN denotes IL-10
T13182 171-174 CC denotes and
T13181 169-170 -COMMA- denotes ,
T13180 159-169 NN denotes production
T13179 150-158 NN denotes cytokine
T13178 143-149 NN denotes T-cell
T13177 126-142 JJ denotes antigen-specific
T13176 116-125 JJ denotes effective
T13175 112-115 IN denotes for
T13174 104-111 JJ denotes crucial
T13173 101-103 VB denotes is
T13172 93-100 NN denotes pathway
T13171 79-92 JJ denotes costimulatory
T13170 74-78 NN denotes CD28
T13169 70-73 DT denotes The
T13168 64-69 NN denotes cells
T13167 62-63 NN denotes T
T13166 57-61 JJ denotes CD4+
T13165 54-56 NN denotes RA
T13164 51-53 IN denotes in
T13163 40-50 NN denotes production
T13162 34-39 NN denotes IFN-γ
T13161 31-33 IN denotes of
T13160 20-30 NN denotes inhibition
T13159 14-19 NN denotes IL-10
T13158 11-13 TO denotes to
T13157 0-10 NN denotes Resistance
R6415 T13157 T13158 arg1Of Resistance,to
R6416 T13157 T13164 arg1Of Resistance,in
R6417 T13160 T13158 arg2Of inhibition,to
R6418 T13160 T13159 arg1Of inhibition,IL-10
R6419 T13160 T13161 arg1Of inhibition,of
R6420 T13163 T13161 arg2Of production,of
R6421 T13163 T13162 arg1Of production,IFN-γ
R6422 T13168 T13164 arg2Of cells,in
R6423 T13168 T13165 arg1Of cells,RA
R6424 T13168 T13166 arg1Of cells,CD4+
R6425 T13168 T13167 arg1Of cells,T
R6426 T13172 T13169 arg1Of pathway,The
R6427 T13172 T13170 arg1Of pathway,CD28
R6428 T13172 T13171 arg1Of pathway,costimulatory
R6429 T13172 T13173 arg1Of pathway,is
R6430 T13172 T13174 arg1Of pathway,crucial
R6431 T13173 T13182 arg1Of is,and
R6432 T13174 T13173 arg2Of crucial,is
R6433 T13174 T13175 arg1Of crucial,for
R6434 T13180 T13175 arg2Of production,for
R6435 T13180 T13176 arg1Of production,effective
R6436 T13180 T13177 arg1Of production,antigen-specific
R6437 T13180 T13178 arg1Of production,T-cell
R6438 T13180 T13179 arg1Of production,cytokine
R6439 T13182 T13181 arg1Of and,","
R6440 T13183 T13184 arg1Of IL-10,can
R6441 T13183 T13186 arg1Of IL-10,suppress
R6442 T13183 T13190 arg1Of IL-10,inhibiting
R6443 T13186 T13182 arg2Of suppress,and
R6444 T13186 T13184 arg2Of suppress,can
R6445 T13186 T13185 arg1Of suppress,directly
R6446 T13186 T13189 arg1Of suppress,by
R6447 T13188 T13186 arg2Of response,suppress
R6448 T13188 T13187 arg1Of response,this
R6449 T13190 T13189 arg2Of inhibiting,by
R6450 T13190 T13199 arg1Of inhibiting,[
R6451 T13193 T13191 arg1Of phosphorylation,CD28
R6452 T13193 T13192 arg1Of phosphorylation,tyrosine
R6453 T13193 T13194 arg1Of phosphorylation,and
R6454 T13194 T13190 arg2Of and,inhibiting
R6455 T13195 T13194 arg2Of binding,and
R6456 T13195 T13196 arg1Of binding,of
R6457 T13198 T13196 arg2Of 3-kinase,of
R6458 T13198 T13197 arg1Of 3-kinase,phosphatidylinositol
R6459 T13200 T13199 arg2Of 24,[
R6460 T13201 T13199 arg3Of ],[
R6461 T13203 T13202 arg1Of evaluate,To
R6462 T13205 T13203 arg2Of responsiveness,evaluate
R6463 T13205 T13204 arg1Of responsiveness,the
R6464 T13205 T13206 arg1Of responsiveness,of
R6465 T13205 T13211 arg1Of responsiveness,to
R6466 T13210 T13206 arg2Of cells,of
R6467 T13210 T13207 arg1Of cells,RA
R6468 T13210 T13208 arg1Of cells,CD4+
R6469 T13210 T13209 arg1Of cells,T
R6470 T13212 T13211 arg2Of IL-10,to
R6471 T13218 T13214 arg2Of cells,purified
R6472 T13218 T13215 arg1Of cells,PB
R6473 T13218 T13216 arg1Of cells,CD4+
R6474 T13218 T13217 arg1Of cells,T
R6475 T13218 T13219 arg1Of cells,from
R6476 T13218 T13226 arg1Of cells,from
R6477 T13218 T13230 arg1Of cells,were
R6478 T13218 T13231 arg2Of cells,stimulated
R6479 T13219 T13225 arg1Of from,and
R6480 T13221 T13219 arg2Of patients,from
R6481 T13221 T13220 arg1Of patients,three
R6482 T13221 T13222 arg1Of patients,with
R6483 T13224 T13222 arg2Of RA,with
R6484 T13224 T13223 arg1Of RA,active
R6485 T13226 T13225 arg2Of from,and
R6486 T13229 T13226 arg2Of controls,from
R6487 T13229 T13227 arg1Of controls,three
R6488 T13229 T13228 arg1Of controls,healthy
R6489 T13231 T13230 arg2Of stimulated,were
R6490 T13231 T13250 arg1Of stimulated,and
R6491 T13235 T13233 arg2Of antibody,immobilized
R6492 T13235 T13234 arg1Of antibody,anti-CD3
R6493 T13235 T13236 arg1Of antibody,and
R6494 T13236 T13231 arg1Of and,stimulated
R6495 T13236 T13232 arg2Of and,by
R6496 T13236 T13239 arg1Of and,with
R6497 T13236 T13241 arg1Of and,without
R6498 T13238 T13236 arg2Of antibody,and
R6499 T13238 T13237 arg1Of antibody,anti-CD28
R6500 T13239 T13240 arg1Of with,or
R6501 T13241 T13240 arg2Of without,or
R6502 T13243 T13239 arg2Of concentrations,with
R6503 T13243 T13241 arg2Of concentrations,without
R6504 T13243 T13242 arg1Of concentrations,diluted
R6505 T13243 T13244 arg1Of concentrations,of
R6506 T13245 T13244 arg2Of IL-10,of
R6507 T13245 T13246 arg1Of IL-10,for
R6508 T13248 T13246 arg2Of hours,for
R6509 T13248 T13247 arg1Of hours,36
R6510 T13250 T13202 modOf and,To
R6511 T13250 T13213 arg1Of and,","
R6512 T13250 T13249 arg1Of and,","
R6513 T13252 T13251 arg1Of production,IFN-γ
R6514 T13252 T13253 arg1Of production,was
R6515 T13252 T13254 arg2Of production,measured
R6516 T13254 T13250 arg2Of measured,and
R6517 T13254 T13253 arg2Of measured,was
R6518 T13256 T13254 arg1Of ELISA,measured
R6519 T13256 T13255 arg2Of ELISA,by
R6520 T13258 T13257 arg2Of shown,As
R6521 T13258 T13259 arg1Of shown,in
R6522 T13260 T13259 arg2Of Fig.,in
R6523 T13260 T13261 arg1Of Fig.,1
R6524 T13264 T13263 arg1Of production,IFN-γ
R6525 T13264 T13265 arg1Of production,by
R6526 T13264 T13271 arg1Of production,was
R6527 T13264 T13273 arg2Of production,inhibited
R6528 T13270 T13265 arg2Of cells,by
R6529 T13270 T13266 arg2Of cells,activated
R6530 T13270 T13267 arg1Of cells,normal
R6531 T13270 T13268 arg1Of cells,CD4+
R6532 T13270 T13269 arg1Of cells,T
R6533 T13273 T13257 arg1Of inhibited,As
R6534 T13273 T13262 arg1Of inhibited,","
R6535 T13273 T13271 arg2Of inhibited,was
R6536 T13273 T13272 arg1Of inhibited,mostly
R6537 T13273 T13274 arg1Of inhibited,at
R6538 T13273 T13276 arg1Of inhibited,as
R6539 T13275 T13274 arg2Of concentrations,at
R6540 T13276 T13277 arg1Of as,low
R6541 T13276 T13278 arg1Of as,as
R6542 T13279 T13280 arg1Of 1,ng/ml
R6543 T13281 T13278 arg2Of IL-10,as
R6544 T13281 T13279 arg1Of IL-10,1
R6545 T13287 T13284 arg1Of cells,RA
R6546 T13287 T13285 arg1Of cells,CD4+
R6547 T13287 T13286 arg1Of cells,T
R6548 T13287 T13288 arg1Of cells,were
R6549 T13287 T13289 arg1Of cells,able
R6550 T13287 T13291 arg1Of cells,produce
R6551 T13288 T13304 arg1Of were,and
R6552 T13289 T13288 arg2Of able,were
R6553 T13291 T13289 arg2Of produce,able
R6554 T13291 T13290 arg1Of produce,to
R6555 T13291 T13296 arg1Of produce,in
R6556 T13293 T13291 arg2Of amounts,produce
R6557 T13293 T13292 arg1Of amounts,significant
R6558 T13293 T13294 arg1Of amounts,of
R6559 T13295 T13294 arg2Of IFN-γ,of
R6560 T13296 T13297 arg1Of in,the
R6561 T13296 T13299 arg1Of in,of
R6562 T13298 T13296 arg2Of presence,in
R6563 T13300 T13301 arg1Of 1,ng/ml
R6564 T13302 T13296 arg3Of IL-10,in
R6565 T13302 T13300 arg1Of IL-10,1
R6566 T13304 T13282 arg1Of and,However
R6567 T13304 T13283 arg1Of and,","
R6568 T13304 T13303 arg1Of and,","
R6569 T13306 T13307 arg1Of maximal,but
R6570 T13309 T13307 arg2Of complete,but
R6571 T13309 T13308 arg1Of complete,not
R6572 T13310 T13305 arg1Of inhibition,the
R6573 T13310 T13306 arg1Of inhibition,maximal
R6574 T13310 T13309 arg1Of inhibition,complete
R6575 T13310 T13311 arg1Of inhibition,by
R6576 T13310 T13313 arg1Of inhibition,was
R6577 T13310 T13314 arg2Of inhibition,obtained
R6578 T13312 T13311 arg2Of IL-10,by
R6579 T13314 T13304 arg2Of obtained,and
R6580 T13314 T13313 arg2Of obtained,was
R6581 T13314 T13315 arg1Of obtained,at
R6582 T13317 T13315 arg2Of ng/ml,at
R6583 T13317 T13316 arg1Of ng/ml,10–100
R6584 T13318 T13320 arg1Of We,compared
R6585 T13320 T13319 arg1Of compared,thus
R6586 T13320 T13326 arg1Of compared,by
R6587 T13320 T13330 arg1Of compared,after
R6588 T13320 T13335 arg1Of compared,in
R6589 T13322 T13320 arg2Of levels,compared
R6590 T13322 T13321 arg1Of levels,the
R6591 T13322 T13323 arg1Of levels,of
R6592 T13325 T13323 arg2Of production,of
R6593 T13325 T13324 arg1Of production,IFN-γ
R6594 T13329 T13326 arg2Of cells,by
R6595 T13329 T13327 arg1Of cells,CD4+
R6596 T13329 T13328 arg1Of cells,T
R6597 T13331 T13332 arg1Of CD3,and
R6598 T13333 T13332 arg2Of CD28,and
R6599 T13334 T13330 arg2Of costimulation,after
R6600 T13334 T13331 arg1Of costimulation,CD3
R6601 T13334 T13333 arg1Of costimulation,CD28
R6602 T13335 T13336 arg1Of in,the
R6603 T13335 T13338 arg1Of in,of
R6604 T13337 T13335 arg2Of presence,in
R6605 T13339 T13340 arg1Of 1,ng/ml
R6606 T13341 T13335 arg3Of IL-10,in
R6607 T13341 T13339 arg1Of IL-10,1
R6608 T13341 T13342 arg1Of IL-10,in
R6609 T13341 T13376 arg1Of IL-10,in
R6610 T13342 T13375 arg1Of in,and
R6611 T13344 T13343 arg1Of patients,RA
R6612 T13344 T13345 arg1Of patients,with
R6613 T13344 T13348 arg1Of patients,(
R6614 T13344 T13359 arg1Of patients,and
R6615 T13347 T13345 arg2Of disease,with
R6616 T13347 T13346 arg1Of disease,active
R6617 T13351 T13348 arg2Of joints,(
R6618 T13351 T13349 arg1Of joints,multiple
R6619 T13351 T13350 arg1Of joints,inflammatory
R6620 T13351 T13352 arg1Of joints,","
R6621 T13357 T13352 arg2Of mg/l,","
R6622 T13357 T13353 arg1Of mg/l,CRP
R6623 T13357 T13354 arg1Of mg/l,level
R6624 T13357 T13355 arg1Of mg/l,≥
R6625 T13357 T13356 arg1Of mg/l,10
R6626 T13358 T13348 arg3Of ),(
R6627 T13359 T13342 arg2Of and,in
R6628 T13361 T13359 arg2Of disease,and
R6629 T13361 T13360 arg1Of disease,inactive
R6630 T13361 T13362 arg1Of disease,(
R6631 T13361 T13372 arg1Of disease,[
R6632 T13363 T13362 arg2Of in,(
R6633 T13364 T13363 arg2Of remission,in
R6634 T13364 T13365 arg1Of remission,","
R6635 T13367 T13365 arg2Of level,","
R6636 T13367 T13366 arg1Of level,CRP
R6637 T13367 T13370 arg1Of level,mg/l
R6638 T13369 T13368 arg1Of 10,<
R6639 T13370 T13369 arg1Of mg/l,10
R6640 T13371 T13362 arg3Of ),(
R6641 T13373 T13372 arg2Of 26,[
R6642 T13374 T13372 arg3Of ],[
R6643 T13376 T13375 arg2Of in,and
R6644 T13378 T13376 arg2Of controls,in
R6645 T13378 T13377 arg1Of controls,healthy
R6646 T13379 T13380 arg1Of There,were
R6647 T13380 T13399 arg1Of were,but
R6648 T13383 T13382 arg1Of significant,statistically
R6649 T13384 T13380 arg2Of differences,were
R6650 T13384 T13381 arg1Of differences,no
R6651 T13384 T13383 arg1Of differences,significant
R6652 T13384 T13385 arg1Of differences,in
R6653 T13387 T13385 arg2Of production,in
R6654 T13387 T13386 arg1Of production,IFN-γ
R6655 T13387 T13388 arg1Of production,without
R6656 T13389 T13388 arg2Of IL-10,without
R6657 T13389 T13390 arg1Of IL-10,among
R6658 T13393 T13390 arg2Of groups,among
R6659 T13393 T13391 arg1Of groups,these
R6660 T13393 T13392 arg1Of groups,three
R6661 T13393 T13394 arg1Of groups,(
R6662 T13396 T13394 arg2Of 2a,(
R6663 T13396 T13395 arg1Of 2a,Fig.
R6664 T13397 T13394 arg3Of ),(
R6665 T13399 T13398 arg1Of but,","
R6666 T13402 T13400 arg1Of effect,the
R6667 T13402 T13401 arg1Of effect,inhibitory
R6668 T13402 T13403 arg1Of effect,of
R6669 T13402 T13405 arg1Of effect,on
R6670 T13402 T13408 arg1Of effect,was
R6671 T13402 T13410 arg2Of effect,limited
R6672 T13404 T13403 arg2Of IL-10,of
R6673 T13407 T13405 arg2Of production,on
R6674 T13407 T13406 arg1Of production,IFN-γ
R6675 T13410 T13399 arg2Of limited,but
R6676 T13410 T13408 arg2Of limited,was
R6677 T13410 T13409 arg1Of limited,significantly
R6678 T13410 T13411 arg1Of limited,in
R6679 T13410 T13416 arg1Of limited,as
R6680 T13410 T13453 arg1Of limited,(
R6681 T13415 T13411 arg2Of group,in
R6682 T13415 T13412 arg1Of group,the
R6683 T13415 T13413 arg1Of group,active
R6684 T13415 T13414 arg1Of group,RA
R6685 T13417 T13416 arg2Of compared,as
R6686 T13417 T13418 arg1Of compared,with
R6687 T13422 T13419 arg1Of group,the
R6688 T13422 T13420 arg1Of group,inactive
R6689 T13422 T13421 arg1Of group,RA
R6690 T13422 T13423 arg1Of group,and
R6691 T13423 T13418 arg2Of and,with
R6692 T13425 T13423 arg2Of controls,and
R6693 T13425 T13424 arg1Of controls,healthy
R6694 T13425 T13426 arg1Of controls,(
R6695 T13428 T13426 arg2Of decrease,(
R6696 T13428 T13427 arg1Of decrease,percentage
R6697 T13428 T13429 arg1Of decrease,:
R6698 T13431 T13429 arg2Of RA,:
R6699 T13431 T13430 arg1Of RA,active
R6700 T13431 T13432 arg1Of RA,","
R6701 T13431 T13437 arg1Of RA,;
R6702 T13433 T13434 arg1Of 2.9,±
R6703 T13435 T13434 arg2Of 14.4,±
R6704 T13436 T13432 arg2Of %,","
R6705 T13436 T13433 arg1Of %,2.9
R6706 T13436 T13435 arg1Of %,14.4
R6707 T13439 T13437 arg2Of RA,;
R6708 T13439 T13438 arg1Of RA,inactive
R6709 T13439 T13440 arg1Of RA,","
R6710 T13439 T13445 arg1Of RA,;
R6711 T13441 T13442 arg1Of 45.6,±
R6712 T13443 T13442 arg2Of 14.4,±
R6713 T13444 T13440 arg2Of %,","
R6714 T13444 T13441 arg1Of %,45.6
R6715 T13444 T13443 arg1Of %,14.4
R6716 T13446 T13445 arg2Of controls,;
R6717 T13446 T13447 arg1Of controls,","
R6718 T13451 T13447 arg2Of %,","
R6719 T13451 T13448 arg1Of %,65.8
R6720 T13451 T13449 arg1Of %,±
R6721 T13451 T13450 arg1Of %,7.9
R6722 T13452 T13426 arg3Of ),(
R6723 T13455 T13453 arg2Of 2b,(
R6724 T13455 T13454 arg1Of 2b,Fig.
R6725 T13456 T13453 arg3Of ),(
R6726 T13459 T13457 arg2Of consequence,As
R6727 T13459 T13458 arg1Of consequence,a
R6728 T13463 T13461 arg1Of cells,CD4+
R6729 T13463 T13462 arg1Of cells,T
R6730 T13463 T13464 arg1Of cells,from
R6731 T13463 T13468 arg1Of cells,produced
R6732 T13467 T13464 arg2Of patients,from
R6733 T13467 T13465 arg1Of patients,active
R6734 T13467 T13466 arg1Of patients,RA
R6735 T13468 T13457 arg1Of produced,As
R6736 T13468 T13460 arg1Of produced,","
R6737 T13468 T13473 arg1Of produced,in
R6738 T13470 T13468 arg2Of levels,produced
R6739 T13470 T13469 arg1Of levels,higher
R6740 T13470 T13471 arg1Of levels,of
R6741 T13472 T13471 arg2Of IFN-γ,of
R6742 T13475 T13473 arg2Of presence,in
R6743 T13475 T13474 arg1Of presence,the
R6744 T13475 T13476 arg1Of presence,of
R6745 T13475 T13480 arg1Of presence,than
R6746 T13477 T13478 arg1Of 1,ng/ml
R6747 T13479 T13476 arg2Of IL-10,of
R6748 T13479 T13477 arg1Of IL-10,1
R6749 T13481 T13480 arg2Of did,than
R6750 T13485 T13481 arg1Of cells,did
R6751 T13485 T13482 arg1Of cells,normal
R6752 T13485 T13483 arg1Of cells,CD4+
R6753 T13485 T13484 arg1Of cells,T
R6754 T13485 T13486 arg1Of cells,(
R6755 T13488 T13486 arg2Of 2a,(
R6756 T13488 T13487 arg1Of 2a,Fig.
R6757 T13489 T13486 arg3Of ),(
R6758 T13491 T13490 arg2Of addition,In
R6759 T13493 T13494 arg1Of we,compared
R6760 T13494 T13490 arg1Of compared,In
R6761 T13494 T13492 arg1Of compared,","
R6762 T13494 T13497 arg1Of compared,by
R6763 T13494 T13501 arg1Of compared,after
R6764 T13496 T13494 arg2Of production,compared
R6765 T13496 T13495 arg1Of production,IL-2
R6766 T13500 T13497 arg2Of cells,by
R6767 T13500 T13498 arg1Of cells,CD4+
R6768 T13500 T13499 arg1Of cells,T
R6769 T13502 T13503 arg1Of CD3,and
R6770 T13504 T13503 arg2Of CD28,and
R6771 T13505 T13501 arg2Of costimulation,after
R6772 T13505 T13502 arg1Of costimulation,CD3
R6773 T13505 T13504 arg1Of costimulation,CD28
R6774 T13505 T13506 arg1Of costimulation,in
R6775 T13505 T13516 arg1Of costimulation,in
R6776 T13506 T13515 arg1Of in,and
R6777 T13508 T13506 arg2Of presence,in
R6778 T13508 T13507 arg1Of presence,the
R6779 T13508 T13509 arg1Of presence,of
R6780 T13508 T13511 arg1Of presence,in
R6781 T13510 T13509 arg2Of IL-10,of
R6782 T13514 T13511 arg2Of patients,in
R6783 T13514 T13512 arg1Of patients,active
R6784 T13514 T13513 arg1Of patients,RA
R6785 T13516 T13515 arg2Of in,and
R6786 T13518 T13516 arg2Of controls,in
R6787 T13518 T13517 arg1Of controls,healthy
R6788 T13522 T13521 arg1Of production,IL-2
R6789 T13522 T13523 arg1Of production,was
R6790 T13522 T13525 arg2Of production,affected
R6791 T13525 T13519 arg1Of affected,Similarly
R6792 T13525 T13520 arg1Of affected,","
R6793 T13525 T13523 arg2Of affected,was
R6794 T13525 T13524 arg1Of affected,not
R6795 T13525 T13542 arg1Of affected,","
R6796 T13525 T13543 arg1Of affected,while
R6797 T13527 T13528 arg1Of 1,ng/ml
R6798 T13529 T13525 arg1Of IL-10,affected
R6799 T13529 T13526 arg2Of IL-10,by
R6800 T13529 T13527 arg1Of IL-10,1
R6801 T13529 T13530 arg1Of IL-10,in
R6802 T13532 T13530 arg2Of patients,in
R6803 T13532 T13531 arg1Of patients,RA
R6804 T13532 T13533 arg1Of patients,(
R6805 T13535 T13533 arg2Of decrease,(
R6806 T13535 T13534 arg1Of decrease,percentage
R6807 T13535 T13536 arg1Of decrease,","
R6808 T13540 T13536 arg2Of %,","
R6809 T13540 T13537 arg1Of %,-2.1
R6810 T13540 T13538 arg1Of %,±
R6811 T13540 T13539 arg1Of %,13.8
R6812 T13541 T13533 arg3Of ),(
R6813 T13544 T13545 arg1Of it,was
R6814 T13544 T13547 arg2Of it,reduced
R6815 T13547 T13543 arg2Of reduced,while
R6816 T13547 T13545 arg2Of reduced,was
R6817 T13547 T13546 arg1Of reduced,significantly
R6818 T13547 T13548 arg1Of reduced,in
R6819 T13547 T13551 arg1Of reduced,(
R6820 T13550 T13548 arg2Of controls,in
R6821 T13550 T13549 arg1Of controls,healthy
R6822 T13554 T13553 arg1Of 13.7,±
R6823 T13555 T13551 arg2Of %,(
R6824 T13555 T13552 arg1Of %,61.1
R6825 T13555 T13554 arg1Of %,13.7
R6826 T13555 T13556 arg1Of %,;
R6827 T13557 T13556 arg2Of P,;
R6828 T13557 T13558 arg1Of P,<
R6829 T13557 T13559 arg1Of P,0.05
R6830 T13560 T13551 arg3Of ),(
R6831 T13561 T13562 arg1Of Taken,together
R6832 T13565 T13564 arg1Of results,these
R6833 T13565 T13566 arg1Of results,indicate
R6834 T13566 T13561 modOf indicate,Taken
R6835 T13566 T13563 arg1Of indicate,","
R6836 T13571 T13568 arg1Of cells,RA
R6837 T13571 T13569 arg1Of cells,CD4+
R6838 T13571 T13570 arg1Of cells,T
R6839 T13571 T13572 arg1Of cells,become
R6840 T13571 T13574 arg1Of cells,susceptible
R6841 T13572 T13566 arg2Of become,indicate
R6842 T13572 T13567 arg1Of become,that
R6843 T13572 T13581 arg1Of become,during
R6844 T13574 T13572 arg2Of susceptible,become
R6845 T13574 T13573 arg1Of susceptible,less
R6846 T13574 T13575 arg1Of susceptible,to
R6847 T13578 T13575 arg2Of effect,to
R6848 T13578 T13576 arg1Of effect,the
R6849 T13578 T13577 arg1Of effect,immunoregulatory
R6850 T13578 T13579 arg1Of effect,of
R6851 T13580 T13579 arg2Of IL-10,of
R6852 T13584 T13581 arg2Of phase,during
R6853 T13584 T13582 arg1Of phase,the
R6854 T13584 T13583 arg1Of phase,active

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T12929 2299-2304 Protein denotes IL-10
T12913 1092-1097 Protein denotes IL-10
T12912 1046-1050 Protein denotes CD28
T12911 1038-1041 Protein denotes CD3
T12910 1019-1022 Protein denotes CD4
T12909 999-1004 Protein denotes IFN-γ
T12908 932-937 Protein denotes IL-10
T12907 878-883 Protein denotes IL-10
T12906 845-850 Protein denotes IFN-γ
T12905 788-791 Protein denotes CD4
T12904 769-774 Protein denotes IL-10
T12903 699-702 Protein denotes CD4
T12902 662-667 Protein denotes IFN-γ
T12901 602-607 Protein denotes IFN-γ
T12900 578-583 Protein denotes IL-10
T12899 522-526 Protein denotes CD28
T12898 500-503 Protein denotes CD3
T12897 384-387 Protein denotes CD4
T12896 365-370 Protein denotes IL-10
T12895 349-352 Protein denotes CD4
T12894 231-235 Protein denotes CD28
T12893 175-180 Protein denotes IL-10
T12892 74-78 Protein denotes CD28
T12891 57-60 Protein denotes CD4
T12890 34-39 Protein denotes IFN-γ
T12889 14-19 Protein denotes IL-10
T12928 2228-2231 Protein denotes CD4
T12927 2042-2047 Protein denotes IL-10
T12926 1998-2002 Protein denotes IL-2
T12925 1934-1939 Protein denotes IL-10
T12924 1896-1900 Protein denotes CD28
T12923 1869-1872 Protein denotes CD4
T12922 1850-1854 Protein denotes IL-2
T12921 1801-1804 Protein denotes CD4
T12920 1779-1784 Protein denotes IL-10
T12919 1746-1751 Protein denotes IFN-γ
T12918 1683-1686 Protein denotes CD4
T12917 1432-1437 Protein denotes IFN-γ
T12916 1423-1428 Protein denotes IL-10
T12915 1352-1357 Protein denotes IL-10
T12914 1327-1332 Protein denotes IFN-γ

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T13115 1998-2002 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T13114 1850-1854 http://www.uniprot.org/uniprot/P60568 denotes IL-2
T13113 1888-1891 http://www.uniprot.org/uniprot/P09693 denotes CD3
T13112 1038-1041 http://www.uniprot.org/uniprot/P09693 denotes CD3
T13111 500-503 http://www.uniprot.org/uniprot/P09693 denotes CD3
T13110 1888-1891 http://www.uniprot.org/uniprot/P07766 denotes CD3
T13109 1038-1041 http://www.uniprot.org/uniprot/P07766 denotes CD3
T13108 500-503 http://www.uniprot.org/uniprot/P07766 denotes CD3
T13107 1888-1891 http://www.uniprot.org/uniprot/P04234 denotes CD3
T13106 1038-1041 http://www.uniprot.org/uniprot/P04234 denotes CD3
T13105 500-503 http://www.uniprot.org/uniprot/P04234 denotes CD3
T13104 1888-1891 http://www.uniprot.org/uniprot/P20963 denotes CD3
T13103 1038-1041 http://www.uniprot.org/uniprot/P20963 denotes CD3
T13102 500-503 http://www.uniprot.org/uniprot/P20963 denotes CD3
T13101 1896-1900 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13100 1046-1050 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13099 522-526 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13098 231-235 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13097 74-78 http://www.uniprot.org/uniprot/P10747 denotes CD28
T13096 2228-2231 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13095 1869-1872 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13094 1801-1804 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13093 1683-1686 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13092 1019-1022 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13091 788-791 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13090 699-702 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13089 384-387 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13088 349-352 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13087 57-60 http://www.uniprot.org/uniprot/P01730 denotes CD4
T13086 1746-1751 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13085 1432-1437 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13073 1352-1357 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13072 1092-1097 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13071 932-937 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13070 878-883 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13069 769-774 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13068 578-583 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13067 365-370 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13066 175-180 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13065 14-19 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13084 1327-1332 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13083 999-1004 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13082 845-850 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13081 662-667 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13080 602-607 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13079 34-39 http://www.uniprot.org/uniprot/P01579 denotes IFN-γ
T13078 2299-2304 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13077 2042-2047 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13076 1934-1939 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13075 1779-1784 http://www.uniprot.org/uniprot/P22301 denotes IL-10
T13074 1423-1428 http://www.uniprot.org/uniprot/P22301 denotes IL-10

GO-BP

Id Subject Object Predicate Lexical cue
T12824 1998-2013 http://purl.obolibrary.org/obo/GO_0032663 denotes IL-2 production
T12823 1850-1865 http://purl.obolibrary.org/obo/GO_0032663 denotes IL-2 production
T12822 1998-2013 http://purl.obolibrary.org/obo/GO_0032623 denotes IL-2 production
T12821 1850-1865 http://purl.obolibrary.org/obo/GO_0032623 denotes IL-2 production
T12820 666-691 http://purl.obolibrary.org/obo/GO_0032729 denotes γ production by activated
T12819 245-260 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T12818 159-180 http://purl.obolibrary.org/obo/GO_0032613 denotes production, and IL-10
T12817 159-180 http://purl.obolibrary.org/obo/GO_0032653 denotes production, and IL-10
T12816 150-169 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T12815 145-169 http://purl.obolibrary.org/obo/GO_0035745 denotes cell cytokine production
T12814 145-169 http://purl.obolibrary.org/obo/GO_0035744 denotes cell cytokine production
T12813 145-169 http://purl.obolibrary.org/obo/GO_0002368 denotes cell cytokine production
T12812 145-169 http://purl.obolibrary.org/obo/GO_0032762 denotes cell cytokine production
T12811 145-169 http://purl.obolibrary.org/obo/GO_0002371 denotes cell cytokine production
T12810 145-169 http://purl.obolibrary.org/obo/GO_0002370 denotes cell cytokine production
T12809 143-169 http://purl.obolibrary.org/obo/GO_0002724 denotes T-cell cytokine production
T12808 143-169 http://purl.obolibrary.org/obo/GO_0002369 denotes T-cell cytokine production
T12807 20-39 http://purl.obolibrary.org/obo/GO_1902714 denotes inhibition of IFN-γ

GO-CC

Id Subject Object Predicate Lexical cue
T12964 527-535 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T12963 504-512 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T12962 527-535 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T12961 504-512 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T12960 2235-2240 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12959 1876-1881 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12958 1808-1813 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12957 1690-1695 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12956 1026-1031 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12955 795-800 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12954 706-711 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12953 391-396 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12952 356-361 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12951 64-69 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GO-MF

Id Subject Object Predicate Lexical cue
T12950 1998-2002 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T12949 1850-1854 http://purl.obolibrary.org/obo/GO_0005134 denotes IL-2
T12948 527-535 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T12947 504-512 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody
T12946 265-305 http://purl.obolibrary.org/obo/GO_0043548 denotes binding of phosphatidylinositol 3-kinase
T12945 265-298 http://purl.obolibrary.org/obo/GO_0032266 denotes binding of phosphatidylinositol 3
T12944 265-272 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12943 2299-2304 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12942 2042-2047 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12941 1934-1939 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12940 1779-1784 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12939 1423-1428 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12938 1352-1357 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12937 1092-1097 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12936 932-937 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12935 878-883 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12934 769-774 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12933 578-583 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12932 365-370 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12931 175-180 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10
T12930 14-19 http://purl.obolibrary.org/obo/GO_0005141 denotes IL-10

sentences

Id Subject Object Predicate Lexical cue
T12806 2181-2329 Sentence denotes Taken together, these results indicate that RA CD4+ T cells become less susceptible to the immunoregulatory effect of IL-10 during the active phase.
T12805 1987-2180 Sentence denotes Similarly, IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease, -2.1 ± 13.8%), while it was significantly reduced in healthy controls (61.1 ± 13.7%; P < 0.05).
T12804 1825-1986 Sentence denotes In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation in the presence of IL-10 in active RA patients and in healthy controls.
T12803 1665-1824 Sentence denotes As a consequence, CD4+ T cells from active RA patients produced higher levels of IFN-γ in the presence of 1 ng/ml IL-10 than did normal CD4+ T cells (Fig. 2a).
T12802 1272-1664 Sentence denotes There were no statistically significant differences in IFN-γ production without IL-10 among these three groups (Fig. 2a), but the inhibitory effect of IL-10 on IFN-γ production was significantly limited in the active RA group as compared with the inactive RA group and healthy controls (percentage decrease: active RA, 2.9 ± 14.4%; inactive RA, 45.6 ± 14.4%; controls, 65.8 ± 7.9%) (Fig. 2b).
T12801 968-1271 Sentence denotes We thus compared the levels of IFN-γ production by CD4+ T cells after CD3 and CD28 costimulation in the presence of 1 ng/ml IL-10 in RA patients with active disease (multiple inflammatory joints, CRP level ≥ 10 mg/l) and inactive disease (in remission, CRP level < 10 mg/l) [26] and in healthy controls.
T12800 776-967 Sentence denotes However, RA CD4+ T cells were able to produce significant amounts of IFN-γ in the presence of 1 ng/ml IL-10, and the maximal but not complete inhibition by IL-10 was obtained at 10–100 ng/ml.
T12799 642-775 Sentence denotes As shown in Fig. 1, IFN-γ production by activated normal CD4+ T cells was mostly inhibited at concentrations as low as 1 ng/ml IL-10.
T12798 312-641 Sentence denotes To evaluate the responsiveness of RA CD4+ T cells to IL-10, purified PB CD4+ T cells from three patients with active RA and from three healthy controls were stimulated by immobilized anti-CD3 antibody and anti-CD28 antibody with or without diluted concentrations of IL-10 for 36 hours, and IFN-γ production was measured by ELISA.
T12797 70-311 Sentence denotes The CD28 costimulatory pathway is crucial for effective antigen-specific T-cell cytokine production, and IL-10 can directly suppress this response by inhibiting CD28 tyrosine phosphorylation and binding of phosphatidylinositol 3-kinase [24].
T12796 0-69 Sentence denotes Resistance to IL-10 inhibition of IFN-γ production in RA CD4+ T cells
T92 0-69 Sentence denotes Resistance to IL-10 inhibition of IFN-γ production in RA CD4+ T cells
T93 70-311 Sentence denotes The CD28 costimulatory pathway is crucial for effective antigen-specific T-cell cytokine production, and IL-10 can directly suppress this response by inhibiting CD28 tyrosine phosphorylation and binding of phosphatidylinositol 3-kinase [24].
T94 312-641 Sentence denotes To evaluate the responsiveness of RA CD4+ T cells to IL-10, purified PB CD4+ T cells from three patients with active RA and from three healthy controls were stimulated by immobilized anti-CD3 antibody and anti-CD28 antibody with or without diluted concentrations of IL-10 for 36 hours, and IFN-γ production was measured by ELISA.
T95 642-775 Sentence denotes As shown in Fig. 1, IFN-γ production by activated normal CD4+ T cells was mostly inhibited at concentrations as low as 1 ng/ml IL-10.
T96 776-967 Sentence denotes However, RA CD4+ T cells were able to produce significant amounts of IFN-γ in the presence of 1 ng/ml IL-10, and the maximal but not complete inhibition by IL-10 was obtained at 10–100 ng/ml.
T97 968-1271 Sentence denotes We thus compared the levels of IFN-γ production by CD4+ T cells after CD3 and CD28 costimulation in the presence of 1 ng/ml IL-10 in RA patients with active disease (multiple inflammatory joints, CRP level ≥ 10 mg/l) and inactive disease (in remission, CRP level < 10 mg/l) [26] and in healthy controls.
T98 1272-1664 Sentence denotes There were no statistically significant differences in IFN-γ production without IL-10 among these three groups (Fig. 2a), but the inhibitory effect of IL-10 on IFN-γ production was significantly limited in the active RA group as compared with the inactive RA group and healthy controls (percentage decrease: active RA, 2.9 ± 14.4%; inactive RA, 45.6 ± 14.4%; controls, 65.8 ± 7.9%) (Fig. 2b).
T99 1665-1824 Sentence denotes As a consequence, CD4+ T cells from active RA patients produced higher levels of IFN-γ in the presence of 1 ng/ml IL-10 than did normal CD4+ T cells (Fig. 2a).
T100 1825-1986 Sentence denotes In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation in the presence of IL-10 in active RA patients and in healthy controls.
T101 1987-2180 Sentence denotes Similarly, IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease, -2.1 ± 13.8%), while it was significantly reduced in healthy controls (61.1 ± 13.7%; P < 0.05).
T102 2181-2329 Sentence denotes Taken together, these results indicate that RA CD4+ T cells become less susceptible to the immunoregulatory effect of IL-10 during the active phase.

simple1

Id Subject Object Predicate Lexical cue
T13138 1038-1041 Protein denotes CD3
T13137 1019-1022 Protein denotes CD4
T13136 999-1004 Protein denotes IFN-γ
T13135 932-937 Protein denotes IL-10
T13134 878-883 Protein denotes IL-10
T13133 845-850 Protein denotes IFN-γ
T13132 788-791 Protein denotes CD4
T13131 769-774 Protein denotes IL-10
T13130 699-702 Protein denotes CD4
T13129 662-667 Protein denotes IFN-γ
T13128 602-607 Protein denotes IFN-γ
T13127 578-583 Protein denotes IL-10
T13126 522-526 Protein denotes CD28
T13125 500-503 Protein denotes CD3
T13124 384-387 Protein denotes CD4
T13123 365-370 Protein denotes IL-10
T13122 349-352 Protein denotes CD4
T13121 231-235 Protein denotes CD28
T13120 175-180 Protein denotes IL-10
T13119 74-78 Protein denotes CD28
T13118 57-60 Protein denotes CD4
T13117 34-39 Protein denotes IFN-γ
T13116 14-19 Protein denotes IL-10
T13156 2299-2304 Protein denotes IL-10
T13155 2228-2231 Protein denotes CD4
T13154 2042-2047 Protein denotes IL-10
T13153 1998-2002 Protein denotes IL-2
T13152 1934-1939 Protein denotes IL-10
T13151 1896-1900 Protein denotes CD28
T13150 1869-1872 Protein denotes CD4
T13149 1850-1854 Protein denotes IL-2
T13148 1801-1804 Protein denotes CD4
T13147 1779-1784 Protein denotes IL-10
T13146 1746-1751 Protein denotes IFN-γ
T13145 1683-1686 Protein denotes CD4
T13144 1432-1437 Protein denotes IFN-γ
T13143 1423-1428 Protein denotes IL-10
T13142 1352-1357 Protein denotes IL-10
T13141 1327-1332 Protein denotes IFN-γ
T13140 1092-1097 Protein denotes IL-10
T13139 1046-1050 Protein denotes CD28

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T14405 2003-2013 Gene_expression denotes production
T14404 2022-2030 Regulation denotes affected
T14403 1855-1865 Gene_expression denotes production
T14402 1438-1448 Gene_expression denotes production
T14401 1333-1343 Gene_expression denotes production
T14400 1005-1015 Gene_expression denotes production
T14399 814-821 Gene_expression denotes produce
T14398 723-732 Negative_regulation denotes inhibited
T14397 668-678 Gene_expression denotes production
T14396 608-618 Gene_expression denotes production
T14395 245-260 Phosphorylation denotes phosphorylation
T14394 220-230 Negative_regulation denotes inhibiting
T14393 20-30 Negative_regulation denotes inhibition
T14392 40-50 Gene_expression denotes production
T14391 2299-2304 Protein denotes IL-10
T14390 2228-2231 Protein denotes CD4
T14389 2042-2047 Protein denotes IL-10
T14388 1998-2002 Protein denotes IL-2
T14387 1934-1939 Protein denotes IL-10
T14386 1896-1900 Protein denotes CD28
T14385 1869-1872 Protein denotes CD4
T14384 1850-1854 Protein denotes IL-2
T14383 1801-1804 Protein denotes CD4
T14382 1779-1784 Protein denotes IL-10
T14381 1746-1751 Protein denotes IFN-γ
T14380 1683-1686 Protein denotes CD4
T14379 1432-1437 Protein denotes IFN-γ
T14378 1423-1428 Protein denotes IL-10
T14377 1352-1357 Protein denotes IL-10
T14376 1327-1332 Protein denotes IFN-γ
T14375 1092-1097 Protein denotes IL-10
T14351 14-19 Protein denotes IL-10
T14374 1046-1050 Protein denotes CD28
T14373 1038-1041 Protein denotes CD3
T14372 1019-1022 Protein denotes CD4
T14371 999-1004 Protein denotes IFN-γ
T14370 932-937 Protein denotes IL-10
T14369 878-883 Protein denotes IL-10
T14368 845-850 Protein denotes IFN-γ
T14367 788-791 Protein denotes CD4
T14366 769-774 Protein denotes IL-10
T14365 699-702 Protein denotes CD4
T14364 662-667 Protein denotes IFN-γ
T14363 384-387 Protein denotes CD4
T14362 365-370 Protein denotes IL-10
T14361 349-352 Protein denotes CD4
T14360 602-607 Protein denotes IFN-γ
T14359 578-583 Protein denotes IL-10
T14358 522-526 Protein denotes CD28
T14357 500-503 Protein denotes CD3
T14356 231-235 Protein denotes CD28
T14355 175-180 Protein denotes IL-10
T14354 74-78 Protein denotes CD28
T14353 57-60 Protein denotes CD4
T14352 34-39 Protein denotes IFN-γ
R7409 T14352 T14392 themeOf IFN-γ,production
R7410 T14355 T14394 causeOf IL-10,inhibiting
R7411 T14356 T14395 themeOf CD28,phosphorylation
R7412 T14360 T14396 themeOf IFN-γ,production
R7413 T14364 T14397 themeOf IFN-γ,production
R7414 T14368 T14399 themeOf IFN-γ,produce
R7415 T14371 T14400 themeOf IFN-γ,production
R7416 T14376 T14401 themeOf IFN-γ,production
R7417 T14379 T14402 themeOf IFN-γ,production
R7418 T14384 T14403 themeOf IL-2,production
R7419 T14388 T14405 themeOf IL-2,production
R7420 T14392 T14393 themeOf production,inhibition
R7421 T14395 T14394 themeOf phosphorylation,inhibiting
R7422 T14397 T14398 themeOf production,inhibited
R7423 T14405 T14404 themeOf production,affected

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T13642 2127-2134 Negative_regulation denotes reduced
T13641 2022-2030 Regulation denotes affected
T13640 2003-2013 Gene_expression denotes production
T13639 1855-1865 Gene_expression denotes production
T13638 1720-1728 Gene_expression denotes produced
T13637 1438-1448 Gene_expression denotes production
T13636 1333-1343 Gene_expression denotes production
T13635 1005-1015 Gene_expression denotes production
T13634 918-928 Negative_regulation denotes inhibition
T13633 814-821 Gene_expression denotes produce
T13632 668-678 Gene_expression denotes production
T13631 723-732 Negative_regulation denotes inhibited
T13630 608-618 Gene_expression denotes production
T13629 220-230 Negative_regulation denotes inhibiting
T13628 245-260 Phosphorylation denotes phosphorylation
T13627 40-50 Gene_expression denotes production
T13626 20-30 Negative_regulation denotes inhibition
T13625 2299-2304 Protein denotes IL-10
T13624 2228-2231 Protein denotes CD4
T13623 2042-2047 Protein denotes IL-10
T13622 1998-2002 Protein denotes IL-2
T13621 1934-1939 Protein denotes IL-10
T13620 1896-1900 Protein denotes CD28
T13619 1869-1872 Protein denotes CD4
T13618 1850-1854 Protein denotes IL-2
T13617 1801-1804 Protein denotes CD4
T13616 1779-1784 Protein denotes IL-10
T13615 1746-1751 Protein denotes IFN-γ
T13614 1683-1686 Protein denotes CD4
T13613 1432-1437 Protein denotes IFN-γ
T13612 1423-1428 Protein denotes IL-10
T13611 1352-1357 Protein denotes IL-10
T13610 1327-1332 Protein denotes IFN-γ
T13609 1092-1097 Protein denotes IL-10
T13608 1046-1050 Protein denotes CD28
T13607 1038-1041 Protein denotes CD3
T13606 1019-1022 Protein denotes CD4
T13605 999-1004 Protein denotes IFN-γ
T13604 932-937 Protein denotes IL-10
T13603 878-883 Protein denotes IL-10
T13602 845-850 Protein denotes IFN-γ
T13601 788-791 Protein denotes CD4
T13600 769-774 Protein denotes IL-10
T13599 699-702 Protein denotes CD4
T13598 662-667 Protein denotes IFN-γ
T13597 384-387 Protein denotes CD4
T13596 365-370 Protein denotes IL-10
T13595 349-352 Protein denotes CD4
T13594 602-607 Protein denotes IFN-γ
T13593 578-583 Protein denotes IL-10
T13592 522-526 Protein denotes CD28
T13591 500-503 Protein denotes CD3
T13590 231-235 Protein denotes CD28
T13589 175-180 Protein denotes IL-10
T13588 74-78 Protein denotes CD28
T13587 57-60 Protein denotes CD4
T13586 34-39 Protein denotes IFN-γ
T13585 14-19 Protein denotes IL-10
R6855 T13586 T13627 themeOf IFN-γ,production
R6856 T13589 T13629 causeOf IL-10,inhibiting
R6857 T13590 T13628 themeOf CD28,phosphorylation
R6858 T13594 T13630 themeOf IFN-γ,production
R6859 T13598 T13632 themeOf IFN-γ,production
R6860 T13602 T13633 themeOf IFN-γ,produce
R6861 T13604 T13634 themeOf IL-10,inhibition
R6862 T13605 T13635 themeOf IFN-γ,production
R6863 T13610 T13636 themeOf IFN-γ,production
R6864 T13613 T13637 themeOf IFN-γ,production
R6865 T13615 T13638 themeOf IFN-γ,produced
R6866 T13618 T13639 themeOf IL-2,production
R6867 T13622 T13640 themeOf IL-2,production
R6868 T13627 T13626 themeOf production,inhibition
R6869 T13628 T13629 themeOf phosphorylation,inhibiting
R6870 T13632 T13631 themeOf production,inhibited
R6871 T13640 T13642 themeOf production,reduced
R6872 T13640 T13641 themeOf production,affected

DLUT931

Id Subject Object Predicate Lexical cue
T14154 2022-2030 Regulation denotes affected
T14153 2003-2013 Gene_expression denotes production
T14152 1855-1865 Gene_expression denotes production
T14151 1729-1735 Positive_regulation denotes higher
T14150 1720-1728 Gene_expression denotes produced
T14149 1312-1323 Regulation denotes differences
T14148 1438-1448 Gene_expression denotes production
T14147 1413-1419 Regulation denotes effect
T14146 1333-1343 Gene_expression denotes production
T14145 1051-1064 Negative_regulation denotes costimulation
T14144 1005-1015 Gene_expression denotes production
T14143 918-928 Negative_regulation denotes inhibition
T14142 814-821 Gene_expression denotes produce
T14141 723-732 Negative_regulation denotes inhibited
T14140 682-691 Positive_regulation denotes activated
T14139 668-678 Gene_expression denotes production
T14138 608-618 Gene_expression denotes production
T14137 220-230 Negative_regulation denotes inhibiting
T14136 245-260 Phosphorylation denotes phosphorylation
T14135 0-10 Positive_regulation denotes Resistance
T14134 20-30 Negative_regulation denotes inhibition
T14133 40-50 Gene_expression denotes production
T14132 2299-2304 Protein denotes IL-10
T14131 2228-2231 Protein denotes CD4
T14130 2042-2047 Protein denotes IL-10
T14129 1998-2002 Protein denotes IL-2
T14128 1934-1939 Protein denotes IL-10
T14127 1896-1900 Protein denotes CD28
T14126 1869-1872 Protein denotes CD4
T14125 1850-1854 Protein denotes IL-2
T14124 1801-1804 Protein denotes CD4
T14123 1779-1784 Protein denotes IL-10
T14122 1746-1751 Protein denotes IFN-γ
T14121 1683-1686 Protein denotes CD4
T14120 1432-1437 Protein denotes IFN-γ
T14119 1423-1428 Protein denotes IL-10
T14118 1352-1357 Protein denotes IL-10
T14117 1327-1332 Protein denotes IFN-γ
T14116 1092-1097 Protein denotes IL-10
T14115 1046-1050 Protein denotes CD28
T14114 1038-1041 Protein denotes CD3
T14113 1019-1022 Protein denotes CD4
T14112 999-1004 Protein denotes IFN-γ
T14111 932-937 Protein denotes IL-10
T14110 878-883 Protein denotes IL-10
T14109 845-850 Protein denotes IFN-γ
T14108 788-791 Protein denotes CD4
T14107 769-774 Protein denotes IL-10
T14106 699-702 Protein denotes CD4
T14105 662-667 Protein denotes IFN-γ
T14104 384-387 Protein denotes CD4
T14103 365-370 Protein denotes IL-10
T14102 349-352 Protein denotes CD4
T14101 602-607 Protein denotes IFN-γ
T14100 578-583 Protein denotes IL-10
T14099 522-526 Protein denotes CD28
T14098 500-503 Protein denotes CD3
T14097 231-235 Protein denotes CD28
T14096 175-180 Protein denotes IL-10
T14095 74-78 Protein denotes CD28
T14094 57-60 Protein denotes CD4
T14093 34-39 Protein denotes IFN-γ
T14092 14-19 Protein denotes IL-10
R7322 T14092 T14135 causeOf IL-10,Resistance
R7323 T14093 T14133 themeOf IFN-γ,production
R7324 T14096 T14137 causeOf IL-10,inhibiting
R7325 T14097 T14136 themeOf CD28,phosphorylation
R7326 T14101 T14138 themeOf IFN-γ,production
R7327 T14105 T14139 themeOf IFN-γ,production
R7328 T14109 T14142 themeOf IFN-γ,produce
R7329 T14110 T14142 themeOf IL-10,produce
R7330 T14111 T14143 themeOf IL-10,inhibition
R7331 T14112 T14144 themeOf IFN-γ,production
R7332 T14114 T14145 themeOf CD3,costimulation
R7333 T14115 T14145 themeOf CD28,costimulation
R7334 T14117 T14146 themeOf IFN-γ,production
R7335 T14118 T14146 themeOf IL-10,production
R7336 T14119 T14147 themeOf IL-10,effect
R7337 T14119 T14148 themeOf IL-10,production
R7338 T14120 T14148 themeOf IFN-γ,production
R7339 T14122 T14150 themeOf IFN-γ,produced
R7340 T14122 T14151 themeOf IFN-γ,higher
R7341 T14125 T14152 themeOf IL-2,production
R7342 T14129 T14153 themeOf IL-2,production
R7343 T14130 T14154 causeOf IL-10,affected
R7344 T14133 T14134 themeOf production,inhibition
R7345 T14134 T14135 themeOf inhibition,Resistance
R7346 T14136 T14137 themeOf phosphorylation,inhibiting
R7347 T14139 T14140 themeOf production,activated
R7348 T14139 T14141 themeOf production,inhibited
R7349 T14146 T14149 themeOf production,differences
R7350 T14146 T14149 themeOf production,differences
R7351 T14148 T14147 themeOf production,effect
R7352 T14148 T14147 themeOf production,effect
R7353 T14150 T14151 themeOf produced,higher
R7354 T14153 T14154 themeOf production,affected

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue Negation
T14350 602-618 Gene_expression denotes IFN-γ production
T14349 1413-1448 Regulation denotes effect of IL-10 on IFN-γ production
T14348 662-711 Gene_expression denotes IFN-γ production by activated normal CD4+ T cells
T14347 1998-2084 Regulation denotes IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease, true
T14346 1327-1382 Gene_expression denotes IFN-γ production without IL-10 among these three groups
T14345 1998-2013 Gene_expression denotes IL-2 production
T14344 1825-1914 Gene_expression denotes In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation
T14343 1896-1914 Positive_regulation denotes CD28 costimulation
T14342 889-950 Binding denotes the maximal but not complete inhibition by IL-10 was obtained
T14341 999-1031 Gene_expression denotes IFN-γ production by CD4+ T cells
T14340 14-69 Negative_regulation denotes IL-10 inhibition of IFN-γ production in RA CD4+ T cells
T14339 1046-1064 Positive_regulation denotes CD28 costimulation
T14338 1429-1448 Gene_expression denotes on IFN-γ production
T14337 1413-1497 Negative_regulation denotes effect of IL-10 on IFN-γ production was significantly limited in the active RA group
T14294 381-396 Entity denotes PB CD4+ T cells
T14293 1384-1387 Protein denotes Fig
T14292 2296-2304 Protein denotes of IL-10
T14291 500-512 Protein denotes CD3 antibody
T14290 365-371 Protein denotes IL-10,
T14289 1950-1952 Protein denotes RA
T14288 1528-1530 Protein denotes RA
T14287 1683-1719 Entity denotes CD4+ T cells from active RA patients
T14286 999-1004 Protein denotes IFN-γ
T14285 1016-1031 Entity denotes by CD4+ T cells
T14284 2225-2240 Entity denotes RA CD4+ T cells
T14283 1038-1041 Protein denotes CD3
T14282 2225-2227 Protein denotes RA
T14281 1746-1751 Protein denotes IFN-γ
T14280 1896-1900 Protein denotes CD28
T14279 343-361 Entity denotes of RA CD4+ T cells
T14278 1655-1658 Protein denotes Fig
T14277 500-503 Protein denotes CD3
T14276 654-657 Protein denotes Fig
T14275 1888-1891 Protein denotes CD3
T14274 381-383 Protein denotes PB
T14273 1604-1615 Protein denotes inactive RA
T14272 1580-1589 Protein denotes active RA
T14271 116-142 Entity denotes effective antigen-specific
T14270 231-235 Protein denotes CD28
T14269 1432-1437 Protein denotes IFN-γ
T14336 31-50 Gene_expression denotes of IFN-γ production
T14335 14-19 Protein denotes IL-10
T14334 785-787 Protein denotes RA
T14333 785-800 Entity denotes RA CD4+ T cells
T14332 1708-1710 Protein denotes RA
T14331 2031-2047 Protein denotes by 1 ng/ml IL-10
T14330 1794-1813 Entity denotes normal CD4+ T cells
T14329 1084-1112 Protein denotes 1 ng/ml IL-10 in RA patients
T14328 1489-1491 Protein denotes RA
T14327 54-69 Entity denotes RA CD4+ T cells
T14326 34-39 Protein denotes IFN-γ
T14325 1352-1357 Protein denotes IL-10
T14324 662-667 Protein denotes IFN-γ
T14323 1221-1224 Protein denotes CRP
T14322 527-535 Protein denotes antibody
T14321 54-56 Protein denotes RA
T14320 1327-1332 Protein denotes IFN-γ
T14319 276-305 Protein denotes phosphatidylinositol 3-kinase
T14318 175-180 Protein denotes IL-10
T14317 2051-2053 Protein denotes RA
T14316 575-597 Protein denotes of IL-10 for 36 hours,
T14315 70-100 Protein denotes The CD28 costimulatory pathway
T14314 679-711 Entity denotes by activated normal CD4+ T cells
T14313 422-431 Protein denotes active RA
T14312 716-774 Protein denotes mostly inhibited at concentrations as low as 1 ng/ml IL-10
T14311 2156-2173 Entity denotes 61.1 ± 13.7%; P <
T14310 1866-1914 Entity denotes by CD4+ T cells after CD3 and CD28 costimulation
T14309 1101-1103 Protein denotes RA
T14308 1771-1784 Protein denotes 1 ng/ml IL-10
T14307 1998-2002 Protein denotes IL-2
T14306 929-937 Protein denotes by IL-10
T14305 842-850 Protein denotes of IFN-γ
T14304 602-607 Protein denotes IFN-γ
T14303 1850-1854 Protein denotes IL-2
T14302 517-526 Protein denotes anti-CD28
T14301 346-348 Protein denotes RA
T14300 1934-1985 Protein denotes IL-10 in active RA patients and in healthy controls
T14299 1164-1167 Protein denotes CRP
T14298 870-883 Protein denotes 1 ng/ml IL-10
T14297 1046-1050 Protein denotes CD28
T14296 1420-1428 Protein denotes of IL-10
T14295 231-260 Entity denotes CD28 tyrosine phosphorylation
R7392 T14269 T14338 themeOf IFN-γ,on IFN-γ production
R7393 T14280 T14343 themeOf CD28,CD28 costimulation
R7394 T14286 T14341 themeOf IFN-γ,IFN-γ production by CD4+ T cells
R7395 T14296 T14349 causeOf of IL-10,effect of IL-10 on IFN-γ production
R7396 T14297 T14339 themeOf CD28,CD28 costimulation
R7397 T14303 T14344 themeOf IL-2,"In addition, we compared IL-2 production by CD4+ T cells after CD3 and CD28 costimulation"
R7398 T14304 T14350 themeOf IFN-γ,IFN-γ production
R7399 T14307 T14345 themeOf IL-2,IL-2 production
R7400 T14320 T14346 themeOf IFN-γ,IFN-γ production without IL-10 among these three groups
R7401 T14324 T14348 themeOf IFN-γ,IFN-γ production by activated normal CD4+ T cells
R7402 T14326 T14336 themeOf IFN-γ,of IFN-γ production
R7403 T14331 T14347 causeOf by 1 ng/ml IL-10,"IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease,"
R7404 T14335 T14340 causeOf IL-10,IL-10 inhibition of IFN-γ production in RA CD4+ T cells
R7405 T14336 T14340 themeOf of IFN-γ production,IL-10 inhibition of IFN-γ production in RA CD4+ T cells
R7406 T14338 T14349 themeOf on IFN-γ production,effect of IL-10 on IFN-γ production
R7407 T14345 T14347 themeOf IL-2 production,"IL-2 production was not affected by 1 ng/ml IL-10 in RA patients (percentage decrease,"
R7408 T14349 T14337 themeOf effect of IL-10 on IFN-γ production,effect of IL-10 on IFN-γ production was significantly limited in the active RA group

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T13988 1815-1819 NNP denotes Fig.
T13987 1814-1815 -LRB- denotes (
T13986 1808-1813 NNS denotes cells
T13985 1806-1807 NNP denotes T
T13984 1804-1805 CD denotes +
T13983 1801-1804 NNP denotes CD4
T13982 1794-1800 JJ denotes normal
T13981 1790-1793 VBD denotes did
T13980 1785-1789 IN denotes than
T13979 1779-1784 NN denotes IL-10
T13978 1773-1778 NN denotes ng/ml
T13977 1771-1772 CD denotes 1
T13976 1768-1770 IN denotes of
T13975 1759-1767 NN denotes presence
T13974 1755-1758 DT denotes the
T13973 1752-1754 IN denotes in
T13972 1746-1751 NNP denotes IFN-γ
T13971 1743-1745 IN denotes of
T13970 1736-1742 NNS denotes levels
T13969 1729-1735 JJR denotes higher
T13968 1720-1728 VBD denotes produced
T13967 1711-1719 NNS denotes patients
T13966 1708-1710 NNP denotes RA
T13965 1701-1707 JJ denotes active
T13964 1696-1700 IN denotes from
T13963 1690-1695 NNS denotes cells
T13962 1688-1689 NNP denotes T
T13961 1686-1687 NNP denotes +
T13960 1683-1686 NNP denotes CD4
T13959 1681-1682 , denotes ,
T13958 1670-1681 NN denotes consequence
T13957 1668-1669 DT denotes a
T13956 1665-1667 IN denotes As
T13955 1663-1664 . denotes .
T13954 1662-1663 -RRB- denotes )
T13953 1660-1662 CD denotes 2b
T13952 1655-1659 NNP denotes Fig.
T13951 1654-1655 -LRB- denotes (
T13950 1652-1653 -RRB- denotes )
T13949 1651-1652 NN denotes %
T13948 1648-1651 CD denotes 7.9
T13947 1646-1647 NN denotes ±
T13946 1641-1645 CD denotes 65.8
T13945 1639-1640 , denotes ,
T13944 1631-1639 NNS denotes controls
T13943 1629-1630 : denotes ;
T13942 1628-1629 NN denotes %
T13941 1624-1628 CD denotes 14.4
T13940 1622-1623 NN denotes ±
T13939 1617-1621 CD denotes 45.6
T13938 1615-1616 , denotes ,
T13937 1613-1615 NNP denotes RA
T13936 1604-1612 JJ denotes inactive
T13935 1602-1603 : denotes ;
T13934 1601-1602 NN denotes %
T13933 1597-1601 CD denotes 14.4
T13932 1595-1596 NN denotes ±
T13931 1591-1594 CD denotes 2.9
T13930 1589-1590 , denotes ,
T13929 1587-1589 NNP denotes RA
T13928 1580-1586 JJ denotes active
T13927 1578-1579 : denotes :
T13926 1570-1578 NN denotes decrease
T13925 1559-1569 NN denotes percentage
T13924 1558-1559 -LRB- denotes (
T13923 1549-1557 NNS denotes controls
T13922 1541-1548 JJ denotes healthy
T13921 1537-1540 CC denotes and
T13920 1531-1536 NN denotes group
T13919 1528-1530 NNP denotes RA
T13918 1519-1527 JJ denotes inactive
T13917 1515-1518 DT denotes the
T13916 1510-1514 IN denotes with
T13915 1501-1509 VBN denotes compared
T13914 1498-1500 IN denotes as
T13913 1492-1497 NN denotes group
T13912 1489-1491 NNP denotes RA
T13911 1482-1488 JJ denotes active
T13910 1478-1481 DT denotes the
T13909 1475-1477 IN denotes in
T13908 1467-1474 VBN denotes limited
T13907 1453-1466 RB denotes significantly
T13906 1449-1452 VBD denotes was
T13905 1438-1448 NN denotes production
T13904 1432-1437 JJ denotes IFN-γ
T13903 1429-1431 IN denotes on
T13902 1423-1428 NN denotes IL-10
T13901 1420-1422 IN denotes of
T13900 1413-1419 NN denotes effect
T13899 1402-1412 JJ denotes inhibitory
T13898 1398-1401 DT denotes the
T13897 1394-1397 CC denotes but
T13896 1392-1393 , denotes ,
T13895 1391-1392 -RRB- denotes )
T13894 1389-1391 CD denotes 2a
T13893 1384-1388 NNP denotes Fig.
T13892 1383-1384 -LRB- denotes (
T13891 1376-1382 NNS denotes groups
T13890 1370-1375 CD denotes three
T13889 1364-1369 DT denotes these
T13888 1358-1363 IN denotes among
T13887 1352-1357 NN denotes IL-10
T13886 1344-1351 IN denotes without
T13885 1333-1343 NN denotes production
T13884 1327-1332 JJ denotes IFN-γ
T13883 1324-1326 IN denotes in
T13882 1312-1323 NNS denotes differences
T13881 1300-1311 JJ denotes significant
T13880 1286-1299 RB denotes statistically
T13879 1283-1285 DT denotes no
T13878 1278-1282 VBD denotes were
T13877 1272-1277 EX denotes There
T13876 1270-1271 . denotes .
T13875 1262-1270 NNS denotes controls
T13874 1254-1261 JJ denotes healthy
T13873 1251-1253 IN denotes in
T13872 1247-1250 CC denotes and
T13871 1245-1246 NNP denotes ]
T13870 1243-1245 CD denotes 26
T13869 1242-1243 NNP denotes [
T13868 1240-1241 -RRB- denotes )
T13867 1236-1240 NN denotes mg/l
T13866 1233-1235 CD denotes 10
T13865 1231-1232 NN denotes <
T13864 1225-1230 NN denotes level
T13863 1221-1224 NNP denotes CRP
T13862 1219-1220 , denotes ,
T13861 1210-1219 NN denotes remission
T13860 1207-1209 IN denotes in
T13859 1206-1207 -LRB- denotes (
T13858 1198-1205 NN denotes disease
T13857 1189-1197 JJ denotes inactive
T13856 1185-1188 CC denotes and
T13855 1183-1184 -RRB- denotes )
T13854 1179-1183 NN denotes mg/l
T13853 1176-1178 CD denotes 10
T13852 1174-1175 NN denotes ≥
T13851 1168-1173 NN denotes level
T13850 1164-1167 NNP denotes CRP
T13849 1162-1163 , denotes ,
T13848 1156-1162 NNS denotes joints
T13847 1143-1155 JJ denotes inflammatory
T13846 1134-1142 JJ denotes multiple
T13845 1133-1134 -LRB- denotes (
T13844 1125-1132 NN denotes disease
T13843 1118-1124 JJ denotes active
T13842 1113-1117 IN denotes with
T13841 1104-1112 NNS denotes patients
T13840 1101-1103 NNP denotes RA
T13839 1098-1100 IN denotes in
T13838 1092-1097 NN denotes IL-10
T13837 1086-1091 NN denotes ng/ml
T13836 1084-1085 CD denotes 1
T13835 1081-1083 IN denotes of
T13834 1072-1080 NN denotes presence
T13833 1068-1071 DT denotes the
T13832 1065-1067 IN denotes in
T13831 1051-1064 NN denotes costimulation
T13830 1046-1050 NNP denotes CD28
T13829 1042-1045 CC denotes and
T13828 1038-1041 NNP denotes CD3
T13827 1032-1037 IN denotes after
T13826 1026-1031 NNS denotes cells
T13825 1024-1025 NNP denotes T
T13824 1022-1023 NNP denotes +
T13823 1019-1022 NNP denotes CD4
T13822 1016-1018 IN denotes by
T13821 1005-1015 NN denotes production
T13820 999-1004 JJ denotes IFN-γ
T13819 996-998 IN denotes of
T13818 989-995 NNS denotes levels
T13817 985-988 DT denotes the
T13816 976-984 VBD denotes compared
T13815 971-975 RB denotes thus
T13814 968-970 PRP denotes We
T13813 966-967 . denotes .
T13812 961-966 NN denotes ng/ml
T13811 957-960 CD denotes 100
T13810 954-956 CD denotes 10
T13809 951-953 IN denotes at
T13808 942-950 VBN denotes obtained
T13807 938-941 VBD denotes was
T13806 932-937 NNP denotes IL-10
T13805 929-931 IN denotes by
T13804 918-928 NN denotes inhibition
T13803 909-917 JJ denotes complete
T13802 905-908 RB denotes not
T13801 901-904 CC denotes but
T13800 893-900 JJ denotes maximal
T13799 889-892 DT denotes the
T13798 885-888 CC denotes and
T13797 883-884 , denotes ,
T13796 878-883 NN denotes IL-10
T13795 872-877 NN denotes ng/ml
T13794 870-871 CD denotes 1
T13793 867-869 IN denotes of
T13792 858-866 NN denotes presence
T13791 854-857 DT denotes the
T13790 851-853 IN denotes in
T13789 845-850 NNP denotes IFN-γ
T13788 842-844 IN denotes of
T13787 834-841 NNS denotes amounts
T13786 822-833 JJ denotes significant
T13785 814-821 VB denotes produce
T13784 811-813 TO denotes to
T13783 806-810 JJ denotes able
T13782 801-805 VBD denotes were
T13781 795-800 NNS denotes cells
T13780 793-794 NNP denotes T
T13779 791-792 VBD denotes +
T13778 788-791 NNP denotes CD4
T13777 785-787 NNP denotes RA
T13776 783-784 , denotes ,
T13775 776-783 RB denotes However
T13774 774-775 . denotes .
T13773 769-774 NN denotes IL-10
T13713 422-428 JJ denotes active
T13712 417-421 IN denotes with
T13711 408-416 NNS denotes patients
T13710 402-407 CD denotes three
T13709 397-401 IN denotes from
T13708 391-396 NNS denotes cells
T13707 389-390 NNP denotes T
T13706 387-388 VBD denotes +
T13705 384-387 NNP denotes CD4
T13704 381-383 NNP denotes PB
T13703 372-380 VBD denotes purified
T13702 370-371 , denotes ,
T13701 365-370 NNP denotes IL-10
T13700 362-364 TO denotes to
T13699 356-361 NNS denotes cells
T13698 354-355 NNP denotes T
T13697 352-353 VBD denotes +
T13696 349-352 NNP denotes CD4
T13695 346-348 NNP denotes RA
T13694 343-345 IN denotes of
T13693 328-342 NN denotes responsiveness
T13692 324-327 DT denotes the
T13691 315-323 VB denotes evaluate
T13690 312-314 TO denotes To
T13689 310-311 . denotes .
T13688 309-310 NNP denotes ]
T13687 307-309 CD denotes 24
T13686 306-307 NNP denotes [
T13685 297-305 JJ denotes 3-kinase
T13684 276-296 NN denotes phosphatidylinositol
T13683 273-275 IN denotes of
T13682 265-272 JJ denotes binding
T13681 261-264 CC denotes and
T13680 245-260 NN denotes phosphorylation
T13679 236-244 NN denotes tyrosine
T13678 231-235 NNP denotes CD28
T13677 220-230 VBG denotes inhibiting
T13676 217-219 IN denotes by
T13675 208-216 NN denotes response
T13674 203-207 DT denotes this
T13673 194-202 VB denotes suppress
T13672 185-193 RB denotes directly
T13671 181-184 MD denotes can
T13670 175-180 NNP denotes IL-10
T13669 171-174 CC denotes and
T13668 169-170 , denotes ,
T13667 159-169 NN denotes production
T13666 150-158 NN denotes cytokine
T13665 143-149 NN denotes T-cell
T13664 126-142 JJ denotes antigen-specific
T13663 116-125 JJ denotes effective
T13662 112-115 IN denotes for
T13661 104-111 JJ denotes crucial
T13660 101-103 VBZ denotes is
T13659 93-100 NN denotes pathway
T13658 79-92 JJ denotes costimulatory
T13657 74-78 CD denotes CD28
T13656 70-73 DT denotes The
T13655 64-69 NNS denotes cells
T13654 62-63 NNP denotes T
T13653 60-61 VBD denotes +
T13652 57-60 NNP denotes CD4
T13651 54-56 NNP denotes RA
T13650 51-53 IN denotes in
T13649 40-50 NN denotes production
T13648 34-39 JJ denotes IFN-γ
T13647 31-33 IN denotes of
T13646 20-30 NN denotes inhibition
T13645 14-19 NNP denotes IL-10
T13644 11-13 TO denotes to
T13643 0-10 NN denotes Resistance
T14091 2328-2329 . denotes .
T14090 2323-2328 NN denotes phase
T14089 2316-2322 JJ denotes active
T14088 2312-2315 DT denotes the
T14087 2305-2311 IN denotes during
T14086 2299-2304 NN denotes IL-10
T14085 2296-2298 IN denotes of
T14084 2289-2295 NN denotes effect
T14083 2272-2288 JJ denotes immunoregulatory
T14082 2268-2271 DT denotes the
T14081 2265-2267 TO denotes to
T14080 2253-2264 JJ denotes susceptible
T14079 2248-2252 RBR denotes less
T14078 2241-2247 VBP denotes become
T14077 2235-2240 NNS denotes cells
T14076 2233-2234 NNP denotes T
T14075 2231-2232 VBD denotes +
T14074 2228-2231 NNP denotes CD4
T14073 2225-2227 NNP denotes RA
T14072 2220-2224 IN denotes that
T14071 2211-2219 VBP denotes indicate
T14070 2203-2210 NNS denotes results
T14069 2197-2202 DT denotes these
T14068 2195-2196 , denotes ,
T14067 2187-2195 RB denotes together
T14066 2181-2186 VBN denotes Taken
T14065 2179-2180 . denotes .
T14064 2178-2179 -RRB- denotes )
T14063 2174-2178 CD denotes 0.05
T14062 2172-2173 NNP denotes <
T14061 2170-2171 NNP denotes P
T14060 2168-2169 : denotes ;
T14059 2167-2168 NN denotes %
T14058 2163-2167 CD denotes 13.7
T14057 2161-2162 CD denotes ±
T14056 2156-2160 CD denotes 61.1
T14055 2155-2156 -LRB- denotes (
T14054 2146-2154 NNS denotes controls
T14053 2138-2145 JJ denotes healthy
T14052 2135-2137 IN denotes in
T14051 2127-2134 VBN denotes reduced
T14050 2113-2126 RB denotes significantly
T14049 2109-2112 VBD denotes was
T14048 2106-2108 PRP denotes it
T14047 2100-2105 IN denotes while
T14046 2098-2099 , denotes ,
T14045 2097-2098 -RRB- denotes )
T14044 2096-2097 NN denotes %
T14043 2092-2096 CD denotes 13.8
T14042 2090-2091 NN denotes ±
T14041 2085-2089 CD denotes -2.1
T14040 2083-2084 , denotes ,
T14039 2075-2083 NN denotes decrease
T14038 2064-2074 NN denotes percentage
T14037 2063-2064 -LRB- denotes (
T14036 2054-2062 NNS denotes patients
T14035 2051-2053 NNP denotes RA
T14034 2048-2050 IN denotes in
T14033 2042-2047 NN denotes IL-10
T14032 2036-2041 NN denotes ng/ml
T14031 2034-2035 CD denotes 1
T14030 2031-2033 IN denotes by
T14029 2022-2030 VBN denotes affected
T14028 2018-2021 RB denotes not
T14027 2014-2017 VBD denotes was
T14026 2003-2013 NN denotes production
T14025 1998-2002 JJ denotes IL-2
T14024 1996-1997 , denotes ,
T14023 1987-1996 RB denotes Similarly
T14022 1985-1986 . denotes .
T14021 1977-1985 NNS denotes controls
T14020 1969-1976 JJ denotes healthy
T14019 1966-1968 IN denotes in
T14018 1962-1965 CC denotes and
T14017 1953-1961 NNS denotes patients
T14016 1950-1952 NNP denotes RA
T14015 1943-1949 JJ denotes active
T14014 1940-1942 IN denotes in
T14013 1934-1939 NN denotes IL-10
T14012 1931-1933 IN denotes of
T14011 1922-1930 NN denotes presence
T14010 1918-1921 DT denotes the
T14009 1915-1917 IN denotes in
T14008 1901-1914 NN denotes costimulation
T14007 1896-1900 NNP denotes CD28
T14006 1892-1895 CC denotes and
T14005 1888-1891 NNP denotes CD3
T14004 1882-1887 IN denotes after
T14003 1876-1881 NNS denotes cells
T14002 1874-1875 NNP denotes T
T14001 1872-1873 NNP denotes +
T14000 1869-1872 NNP denotes CD4
T13999 1866-1868 IN denotes by
T13998 1855-1865 NN denotes production
T13997 1850-1854 JJ denotes IL-2
T13996 1841-1849 VBD denotes compared
T13995 1838-1840 PRP denotes we
T13994 1836-1837 , denotes ,
T13993 1828-1836 NN denotes addition
T13992 1825-1827 IN denotes In
T13991 1823-1824 . denotes .
T13990 1822-1823 -RRB- denotes )
T13989 1820-1822 CD denotes 2a
T13772 763-768 NN denotes ng/ml
T13771 761-762 CD denotes 1
T13770 758-760 IN denotes as
T13769 754-757 JJ denotes low
T13768 751-753 RB denotes as
T13767 736-750 NNS denotes concentrations
T13766 733-735 IN denotes at
T13765 723-732 VBN denotes inhibited
T13764 716-722 RB denotes mostly
T13763 712-715 VBD denotes was
T13762 706-711 NNS denotes cells
T13761 704-705 NNP denotes T
T13760 702-703 CD denotes +
T13759 699-702 NNP denotes CD4
T13758 692-698 JJ denotes normal
T13757 682-691 VBN denotes activated
T13756 679-681 IN denotes by
T13755 668-678 NN denotes production
T13754 662-667 JJ denotes IFN-γ
T13753 660-661 , denotes ,
T13752 659-660 CD denotes 1
T13751 654-658 NNP denotes Fig.
T13750 651-653 IN denotes in
T13749 645-650 VBN denotes shown
T13748 642-644 IN denotes As
T13747 640-641 . denotes .
T13746 635-640 NNP denotes ELISA
T13745 632-634 IN denotes by
T13744 623-631 VBN denotes measured
T13743 619-622 VBD denotes was
T13742 608-618 NN denotes production
T13741 602-607 JJ denotes IFN-γ
T13740 598-601 CC denotes and
T13739 596-597 , denotes ,
T13738 591-596 NNS denotes hours
T13737 588-590 CD denotes 36
T13736 584-587 IN denotes for
T13735 578-583 NN denotes IL-10
T13734 575-577 IN denotes of
T13733 560-574 NNS denotes concentrations
T13732 552-559 VBN denotes diluted
T13731 544-551 IN denotes without
T13730 541-543 CC denotes or
T13729 536-540 IN denotes with
T13728 527-535 NN denotes antibody
T13727 517-526 JJ denotes anti-CD28
T13726 513-516 CC denotes and
T13725 504-512 NN denotes antibody
T13724 495-503 JJ denotes anti-CD3
T13723 483-494 JJ denotes immobilized
T13722 480-482 IN denotes by
T13721 469-479 VBN denotes stimulated
T13720 464-468 VBD denotes were
T13719 455-463 NNS denotes controls
T13718 447-454 JJ denotes healthy
T13717 441-446 CD denotes three
T13716 436-440 IN denotes from
T13715 432-435 CC denotes and
T13714 429-431 NNP denotes RA
R6873 T13643 T13643 ROOT Resistance,Resistance
R6874 T13644 T13643 prep to,Resistance
R6875 T13645 T13644 pobj IL-10,to
R6876 T13646 T13643 conj inhibition,Resistance
R6877 T13647 T13646 prep of,inhibition
R6878 T13648 T13649 amod IFN-γ,production
R6879 T13649 T13647 pobj production,of
R6880 T13650 T13649 prep in,production
R6881 T13651 T13652 compound RA,CD4
R6882 T13652 T13650 pobj CD4,in
R6883 T13653 T13655 amod +,cells
R6884 T13654 T13655 compound T,cells
R6885 T13655 T13643 appos cells,Resistance
R6886 T13656 T13659 det The,pathway
R6887 T13657 T13659 nummod CD28,pathway
R6888 T13658 T13659 amod costimulatory,pathway
R6889 T13659 T13660 nsubj pathway,is
R6890 T13660 T13660 ROOT is,is
R6891 T13661 T13660 acomp crucial,is
R6892 T13662 T13661 prep for,crucial
R6893 T13663 T13667 amod effective,production
R6894 T13664 T13667 amod antigen-specific,production
R6895 T13665 T13667 nmod T-cell,production
R6896 T13666 T13667 compound cytokine,production
R6897 T13667 T13662 pobj production,for
R6898 T13668 T13660 punct ",",is
R6899 T13669 T13660 cc and,is
R6900 T13670 T13673 nsubj IL-10,suppress
R6901 T13671 T13673 aux can,suppress
R6902 T13672 T13673 advmod directly,suppress
R6903 T13673 T13660 conj suppress,is
R6904 T13674 T13675 det this,response
R6905 T13675 T13673 dobj response,suppress
R6906 T13676 T13673 prep by,suppress
R6907 T13677 T13676 pcomp inhibiting,by
R6908 T13678 T13680 compound CD28,phosphorylation
R6909 T13679 T13680 compound tyrosine,phosphorylation
R6910 T13680 T13677 dobj phosphorylation,inhibiting
R6911 T13681 T13680 cc and,phosphorylation
R6912 T13682 T13677 advcl binding,inhibiting
R6913 T13683 T13682 prep of,binding
R6914 T13684 T13686 nmod phosphatidylinositol,[
R6915 T13685 T13686 nmod 3-kinase,[
R6916 T13686 T13688 nmod [,]
R6917 T13687 T13688 nummod 24,]
R6918 T13688 T13683 pobj ],of
R6919 T13689 T13673 punct .,suppress
R6920 T13690 T13691 aux To,evaluate
R6921 T13691 T13703 advcl evaluate,purified
R6922 T13692 T13693 det the,responsiveness
R6923 T13693 T13691 dobj responsiveness,evaluate
R6924 T13694 T13693 prep of,responsiveness
R6925 T13695 T13696 compound RA,CD4
R6926 T13696 T13694 pobj CD4,of
R6927 T13697 T13699 amod +,cells
R6928 T13698 T13699 compound T,cells
R6929 T13699 T13691 dobj cells,evaluate
R6930 T13700 T13691 prep to,evaluate
R6931 T13701 T13700 pobj IL-10,to
R6932 T13702 T13703 punct ",",purified
R6933 T13703 T13703 ROOT purified,purified
R6934 T13704 T13705 compound PB,CD4
R6935 T13705 T13703 dobj CD4,purified
R6936 T13706 T13721 csubjpass +,stimulated
R6937 T13707 T13708 compound T,cells
R6938 T13708 T13706 dobj cells,+
R6939 T13709 T13706 prep from,+
R6940 T13710 T13711 nummod three,patients
R6941 T13711 T13709 pobj patients,from
R6942 T13712 T13711 prep with,patients
R6943 T13713 T13714 amod active,RA
R6944 T13714 T13712 pobj RA,with
R6945 T13715 T13712 cc and,with
R6946 T13716 T13706 prep from,+
R6947 T13717 T13719 nummod three,controls
R6948 T13718 T13719 amod healthy,controls
R6949 T13719 T13716 pobj controls,from
R6950 T13720 T13721 auxpass were,stimulated
R6951 T13721 T13703 ccomp stimulated,purified
R6952 T13722 T13721 agent by,stimulated
R6953 T13723 T13725 amod immobilized,antibody
R6954 T13724 T13725 amod anti-CD3,antibody
R6955 T13725 T13722 pobj antibody,by
R6956 T13726 T13725 cc and,antibody
R6957 T13727 T13728 compound anti-CD28,antibody
R6958 T13728 T13725 conj antibody,antibody
R6959 T13729 T13725 prep with,antibody
R6960 T13730 T13729 cc or,with
R6961 T13731 T13729 conj without,with
R6962 T13732 T13733 amod diluted,concentrations
R6963 T13733 T13731 pobj concentrations,without
R6964 T13734 T13733 prep of,concentrations
R6965 T13735 T13734 pobj IL-10,of
R6966 T13736 T13733 prep for,concentrations
R6967 T13737 T13738 nummod 36,hours
R6968 T13738 T13736 pobj hours,for
R6969 T13739 T13731 punct ",",without
R6970 T13740 T13731 cc and,without
R6971 T13741 T13742 compound IFN-γ,production
R6972 T13742 T13744 nsubjpass production,measured
R6973 T13743 T13744 auxpass was,measured
R6974 T13744 T13703 conj measured,purified
R6975 T13745 T13744 agent by,measured
R6976 T13746 T13745 pobj ELISA,by
R6977 T13747 T13744 punct .,measured
R6978 T13748 T13749 mark As,shown
R6979 T13749 T13765 advcl shown,inhibited
R6980 T13750 T13749 prep in,shown
R6981 T13751 T13750 pobj Fig.,in
R6982 T13752 T13751 nummod 1,Fig.
R6983 T13753 T13751 punct ",",Fig.
R6984 T13754 T13755 compound IFN-γ,production
R6985 T13755 T13765 nsubjpass production,inhibited
R6986 T13756 T13755 prep by,production
R6987 T13757 T13762 amod activated,cells
R6988 T13758 T13762 amod normal,cells
R6989 T13759 T13762 compound CD4,cells
R6990 T13760 T13762 nummod +,cells
R6991 T13761 T13762 compound T,cells
R6992 T13762 T13756 pobj cells,by
R6993 T13763 T13765 auxpass was,inhibited
R6994 T13764 T13765 advmod mostly,inhibited
R6995 T13765 T13765 ROOT inhibited,inhibited
R6996 T13766 T13765 prep at,inhibited
R6997 T13767 T13766 pobj concentrations,at
R6998 T13768 T13769 advmod as,low
R6999 T13769 T13767 amod low,concentrations
R7000 T13770 T13769 prep as,low
R7001 T13771 T13772 nummod 1,ng/ml
R7002 T13772 T13773 compound ng/ml,IL-10
R7003 T13773 T13770 pobj IL-10,as
R7004 T13774 T13765 punct .,inhibited
R7005 T13775 T13782 advmod However,were
R7006 T13776 T13782 punct ",",were
R7007 T13777 T13778 compound RA,CD4
R7008 T13778 T13781 compound CD4,cells
R7009 T13779 T13781 amod +,cells
R7010 T13780 T13781 compound T,cells
R7011 T13781 T13782 nsubj cells,were
R7012 T13782 T13782 ROOT were,were
R7013 T13783 T13782 acomp able,were
R7014 T13784 T13785 aux to,produce
R7015 T13785 T13783 xcomp produce,able
R7016 T13786 T13787 amod significant,amounts
R7017 T13787 T13785 dobj amounts,produce
R7018 T13788 T13787 prep of,amounts
R7019 T13789 T13788 pobj IFN-γ,of
R7020 T13790 T13785 prep in,produce
R7021 T13791 T13792 det the,presence
R7022 T13792 T13790 pobj presence,in
R7023 T13793 T13792 prep of,presence
R7024 T13794 T13796 nummod 1,IL-10
R7025 T13795 T13796 compound ng/ml,IL-10
R7026 T13796 T13793 pobj IL-10,of
R7027 T13797 T13782 punct ",",were
R7028 T13798 T13782 cc and,were
R7029 T13799 T13800 det the,maximal
R7030 T13800 T13808 nsubjpass maximal,obtained
R7031 T13801 T13800 cc but,maximal
R7032 T13802 T13803 neg not,complete
R7033 T13803 T13800 conj complete,maximal
R7034 T13804 T13803 dobj inhibition,complete
R7035 T13805 T13803 prep by,complete
R7036 T13806 T13805 pobj IL-10,by
R7037 T13807 T13808 auxpass was,obtained
R7038 T13808 T13782 conj obtained,were
R7039 T13809 T13808 prep at,obtained
R7040 T13810 T13809 pobj 10,at
R7041 T13811 T13812 nummod 100,ng/ml
R7042 T13812 T13810 appos ng/ml,10
R7043 T13813 T13808 punct .,obtained
R7044 T13814 T13816 nsubj We,compared
R7045 T13815 T13816 advmod thus,compared
R7046 T13816 T13816 ROOT compared,compared
R7047 T13817 T13818 det the,levels
R7048 T13818 T13816 dobj levels,compared
R7049 T13819 T13818 prep of,levels
R7050 T13820 T13821 compound IFN-γ,production
R7051 T13821 T13819 pobj production,of
R7052 T13822 T13821 prep by,production
R7053 T13823 T13826 compound CD4,cells
R7054 T13824 T13826 compound +,cells
R7055 T13825 T13826 compound T,cells
R7056 T13826 T13822 pobj cells,by
R7057 T13827 T13816 prep after,compared
R7058 T13828 T13831 nsubj CD3,costimulation
R7059 T13829 T13828 cc and,CD3
R7060 T13830 T13828 conj CD28,CD3
R7061 T13831 T13827 pobj costimulation,after
R7062 T13832 T13831 prep in,costimulation
R7063 T13833 T13834 det the,presence
R7064 T13834 T13832 pobj presence,in
R7065 T13835 T13834 prep of,presence
R7066 T13836 T13838 nummod 1,IL-10
R7067 T13837 T13838 compound ng/ml,IL-10
R7068 T13838 T13835 pobj IL-10,of
R7069 T13839 T13838 prep in,IL-10
R7070 T13840 T13841 compound RA,patients
R7071 T13841 T13839 pobj patients,in
R7072 T13842 T13841 prep with,patients
R7073 T13843 T13844 amod active,disease
R7074 T13844 T13842 pobj disease,with
R7075 T13845 T13844 punct (,disease
R7076 T13846 T13848 amod multiple,joints
R7077 T13847 T13848 amod inflammatory,joints
R7078 T13848 T13844 appos joints,disease
R7079 T13849 T13844 punct ",",disease
R7080 T13850 T13851 compound CRP,level
R7081 T13851 T13852 nsubj level,≥
R7082 T13852 T13831 npadvmod ≥,costimulation
R7083 T13853 T13854 nummod 10,mg/l
R7084 T13854 T13852 appos mg/l,≥
R7085 T13855 T13852 punct ),≥
R7086 T13856 T13852 cc and,≥
R7087 T13857 T13858 amod inactive,disease
R7088 T13858 T13852 conj disease,≥
R7089 T13859 T13852 punct (,≥
R7090 T13860 T13852 prep in,≥
R7091 T13861 T13860 pobj remission,in
R7092 T13862 T13852 punct ",",≥
R7093 T13863 T13864 compound CRP,level
R7094 T13864 T13852 conj level,≥
R7095 T13865 T13867 nmod <,mg/l
R7096 T13866 T13867 nummod 10,mg/l
R7097 T13867 T13864 appos mg/l,level
R7098 T13868 T13864 punct ),level
R7099 T13869 T13871 nmod [,]
R7100 T13870 T13871 nummod 26,]
R7101 T13871 T13864 nmod ],level
R7102 T13872 T13827 cc and,after
R7103 T13873 T13827 conj in,after
R7104 T13874 T13875 amod healthy,controls
R7105 T13875 T13873 pobj controls,in
R7106 T13876 T13816 punct .,compared
R7107 T13877 T13878 expl There,were
R7108 T13878 T13878 ROOT were,were
R7109 T13879 T13882 det no,differences
R7110 T13880 T13881 advmod statistically,significant
R7111 T13881 T13882 amod significant,differences
R7112 T13882 T13878 attr differences,were
R7113 T13883 T13882 prep in,differences
R7114 T13884 T13885 amod IFN-γ,production
R7115 T13885 T13883 pobj production,in
R7116 T13886 T13882 prep without,differences
R7117 T13887 T13886 pobj IL-10,without
R7118 T13888 T13887 prep among,IL-10
R7119 T13889 T13891 det these,groups
R7120 T13890 T13891 nummod three,groups
R7121 T13891 T13888 pobj groups,among
R7122 T13892 T13893 punct (,Fig.
R7123 T13893 T13878 attr Fig.,were
R7124 T13894 T13893 nummod 2a,Fig.
R7125 T13895 T13893 punct ),Fig.
R7126 T13896 T13878 punct ",",were
R7127 T13897 T13878 cc but,were
R7128 T13898 T13900 det the,effect
R7129 T13899 T13900 amod inhibitory,effect
R7130 T13900 T13908 nsubjpass effect,limited
R7131 T13901 T13900 prep of,effect
R7132 T13902 T13901 pobj IL-10,of
R7133 T13903 T13902 prep on,IL-10
R7134 T13904 T13905 compound IFN-γ,production
R7135 T13905 T13903 pobj production,on
R7136 T13906 T13908 auxpass was,limited
R7137 T13907 T13908 advmod significantly,limited
R7138 T13908 T13878 conj limited,were
R7139 T13909 T13908 prep in,limited
R7140 T13910 T13913 det the,group
R7141 T13911 T13913 amod active,group
R7142 T13912 T13913 compound RA,group
R7143 T13913 T13909 pobj group,in
R7144 T13914 T13908 prep as,limited
R7145 T13915 T13914 prep compared,as
R7146 T13916 T13915 prep with,compared
R7147 T13917 T13920 det the,group
R7148 T13918 T13920 amod inactive,group
R7149 T13919 T13920 compound RA,group
R7150 T13920 T13916 pobj group,with
R7151 T13921 T13920 cc and,group
R7152 T13922 T13923 amod healthy,controls
R7153 T13923 T13920 conj controls,group
R7154 T13924 T13926 punct (,decrease
R7155 T13925 T13926 compound percentage,decrease
R7156 T13926 T13920 appos decrease,group
R7157 T13927 T13926 punct :,decrease
R7158 T13928 T13929 amod active,RA
R7159 T13929 T13926 acl RA,decrease
R7160 T13930 T13929 punct ",",RA
R7161 T13931 T13933 quantmod 2.9,14.4
R7162 T13932 T13933 quantmod ±,14.4
R7163 T13933 T13934 nummod 14.4,%
R7164 T13934 T13929 appos %,RA
R7165 T13935 T13937 punct ;,RA
R7166 T13936 T13937 amod inactive,RA
R7167 T13937 T13929 conj RA,RA
R7168 T13938 T13937 punct ",",RA
R7169 T13939 T13941 quantmod 45.6,14.4
R7170 T13940 T13941 quantmod ±,14.4
R7171 T13941 T13942 nummod 14.4,%
R7172 T13942 T13937 appos %,RA
R7173 T13943 T13937 punct ;,RA
R7174 T13944 T13937 conj controls,RA
R7175 T13945 T13944 punct ",",controls
R7176 T13946 T13948 quantmod 65.8,7.9
R7177 T13947 T13948 quantmod ±,7.9
R7178 T13948 T13949 nummod 7.9,%
R7179 T13949 T13944 appos %,controls
R7180 T13950 T13944 punct ),controls
R7181 T13951 T13937 punct (,RA
R7182 T13952 T13937 npadvmod Fig.,RA
R7183 T13953 T13952 nummod 2b,Fig.
R7184 T13954 T13937 punct ),RA
R7185 T13955 T13908 punct .,limited
R7186 T13956 T13968 prep As,produced
R7187 T13957 T13958 det a,consequence
R7188 T13958 T13956 pobj consequence,As
R7189 T13959 T13968 punct ",",produced
R7190 T13960 T13963 compound CD4,cells
R7191 T13961 T13963 compound +,cells
R7192 T13962 T13963 compound T,cells
R7193 T13963 T13968 nsubj cells,produced
R7194 T13964 T13963 prep from,cells
R7195 T13965 T13967 amod active,patients
R7196 T13966 T13967 compound RA,patients
R7197 T13967 T13964 pobj patients,from
R7198 T13968 T13968 ROOT produced,produced
R7199 T13969 T13970 amod higher,levels
R7200 T13970 T13968 dobj levels,produced
R7201 T13971 T13970 prep of,levels
R7202 T13972 T13971 pobj IFN-γ,of
R7203 T13973 T13968 prep in,produced
R7204 T13974 T13975 det the,presence
R7205 T13975 T13973 pobj presence,in
R7206 T13976 T13975 prep of,presence
R7207 T13977 T13978 nummod 1,ng/ml
R7208 T13978 T13979 compound ng/ml,IL-10
R7209 T13979 T13976 pobj IL-10,of
R7210 T13980 T13981 mark than,did
R7211 T13981 T13968 advcl did,produced
R7212 T13982 T13986 amod normal,cells
R7213 T13983 T13986 nmod CD4,cells
R7214 T13984 T13986 nummod +,cells
R7215 T13985 T13986 compound T,cells
R7216 T13986 T13981 nsubj cells,did
R7217 T13987 T13981 punct (,did
R7218 T13988 T13981 nsubj Fig.,did
R7219 T13989 T13988 nummod 2a,Fig.
R7220 T13990 T13988 punct ),Fig.
R7221 T13991 T13968 punct .,produced
R7222 T13992 T13996 prep In,compared
R7223 T13993 T13992 pobj addition,In
R7224 T13994 T13996 punct ",",compared
R7225 T13995 T13996 nsubj we,compared
R7226 T13996 T13996 ROOT compared,compared
R7227 T13997 T13998 compound IL-2,production
R7228 T13998 T13996 dobj production,compared
R7229 T13999 T13998 prep by,production
R7230 T14000 T14003 compound CD4,cells
R7231 T14001 T14003 compound +,cells
R7232 T14002 T14003 compound T,cells
R7233 T14003 T13999 pobj cells,by
R7234 T14004 T13996 prep after,compared
R7235 T14005 T14008 nsubj CD3,costimulation
R7236 T14006 T14005 cc and,CD3
R7237 T14007 T14005 conj CD28,CD3
R7238 T14008 T14004 pobj costimulation,after
R7239 T14009 T14008 prep in,costimulation
R7240 T14010 T14011 det the,presence
R7241 T14011 T14009 pobj presence,in
R7242 T14012 T14011 prep of,presence
R7243 T14013 T14012 pobj IL-10,of
R7244 T14014 T14013 prep in,IL-10
R7245 T14015 T14017 amod active,patients
R7246 T14016 T14017 compound RA,patients
R7247 T14017 T14014 pobj patients,in
R7248 T14018 T14014 cc and,in
R7249 T14019 T14014 conj in,in
R7250 T14020 T14021 amod healthy,controls
R7251 T14021 T14019 pobj controls,in
R7252 T14022 T13996 punct .,compared
R7253 T14023 T14029 advmod Similarly,affected
R7254 T14024 T14029 punct ",",affected
R7255 T14025 T14026 compound IL-2,production
R7256 T14026 T14029 nsubjpass production,affected
R7257 T14027 T14029 auxpass was,affected
R7258 T14028 T14029 neg not,affected
R7259 T14029 T14029 ROOT affected,affected
R7260 T14030 T14029 agent by,affected
R7261 T14031 T14033 nummod 1,IL-10
R7262 T14032 T14033 compound ng/ml,IL-10
R7263 T14033 T14030 pobj IL-10,by
R7264 T14034 T14033 prep in,IL-10
R7265 T14035 T14036 compound RA,patients
R7266 T14036 T14034 pobj patients,in
R7267 T14037 T14039 punct (,decrease
R7268 T14038 T14039 compound percentage,decrease
R7269 T14039 T14033 appos decrease,IL-10
R7270 T14040 T14039 punct ",",decrease
R7271 T14041 T14042 nummod -2.1,±
R7272 T14042 T14039 appos ±,decrease
R7273 T14043 T14044 nummod 13.8,%
R7274 T14044 T14042 appos %,±
R7275 T14045 T14042 punct ),±
R7276 T14046 T14029 punct ",",affected
R7277 T14047 T14051 mark while,reduced
R7278 T14048 T14051 nsubjpass it,reduced
R7279 T14049 T14051 auxpass was,reduced
R7280 T14050 T14051 advmod significantly,reduced
R7281 T14051 T14029 advcl reduced,affected
R7282 T14052 T14051 prep in,reduced
R7283 T14053 T14054 amod healthy,controls
R7284 T14054 T14052 pobj controls,in
R7285 T14055 T14057 punct (,±
R7286 T14056 T14057 nummod 61.1,±
R7287 T14057 T14029 dep ±,affected
R7288 T14058 T14059 nummod 13.7,%
R7289 T14059 T14057 appos %,±
R7290 T14060 T14062 punct ;,<
R7291 T14061 T14062 compound P,<
R7292 T14062 T14057 appos <,±
R7293 T14063 T14062 nummod 0.05,<
R7294 T14064 T14062 punct ),<
R7295 T14065 T14029 punct .,affected
R7296 T14066 T14071 advcl Taken,indicate
R7297 T14067 T14066 advmod together,Taken
R7298 T14068 T14071 punct ",",indicate
R7299 T14069 T14070 det these,results
R7300 T14070 T14071 nsubj results,indicate
R7301 T14071 T14071 ROOT indicate,indicate
R7302 T14072 T14078 mark that,become
R7303 T14073 T14074 compound RA,CD4
R7304 T14074 T14078 nsubj CD4,become
R7305 T14075 T14077 amod +,cells
R7306 T14076 T14077 compound T,cells
R7307 T14077 T14078 nsubj cells,become
R7308 T14078 T14071 ccomp become,indicate
R7309 T14079 T14080 advmod less,susceptible
R7310 T14080 T14078 acomp susceptible,become
R7311 T14081 T14080 prep to,susceptible
R7312 T14082 T14084 det the,effect
R7313 T14083 T14084 amod immunoregulatory,effect
R7314 T14084 T14081 pobj effect,to
R7315 T14085 T14084 prep of,effect
R7316 T14086 T14085 pobj IL-10,of
R7317 T14087 T14084 prep during,effect
R7318 T14088 T14090 det the,phase
R7319 T14089 T14090 amod active,phase
R7320 T14090 T14087 pobj phase,during
R7321 T14091 T14071 punct .,indicate

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T13064 2299-2304 Protein denotes IL-10
T13063 2228-2231 Protein denotes CD4
T13062 2022-2030 Regulation denotes affected
T13061 2003-2013 Gene_expression denotes production
T13060 1998-2002 Protein denotes IL-2
T13059 1934-1939 Protein denotes IL-10
T13058 1896-1900 Protein denotes CD28
T13057 1888-1891 Protein denotes CD3
T13056 1869-1873 Protein denotes CD4+
T13055 1815-1822 Protein denotes Fig. 2a
T13054 1801-1805 Protein denotes CD4+
T13053 1746-1751 Protein denotes IFN-γ
T13052 1683-1687 Protein denotes CD4+
T13051 1438-1448 Gene_expression denotes production
T13050 1438-1448 Gene_expression denotes production
T13049 1333-1343 Gene_expression denotes production
T13048 1333-1343 Gene_expression denotes production
T13047 1432-1437 Protein denotes IFN-γ
T13046 1423-1428 Protein denotes IL-10
T13045 1384-1391 Protein denotes Fig. 2a
T13044 1327-1332 Protein denotes IFN-γ
T13043 1005-1015 Gene_expression denotes production
T13042 1221-1224 Protein denotes CRP
T13041 1164-1167 Protein denotes CRP
T13040 1046-1050 Protein denotes CD28
T13039 1038-1041 Protein denotes CD3
T13038 1019-1023 Protein denotes CD4+
T13037 999-1004 Protein denotes IFN-γ
T13036 814-821 Gene_expression denotes produce
T13035 932-937 Protein denotes IL-10
T13034 845-850 Protein denotes IFN-γ
T13033 785-791 Protein denotes RA CD4
T13032 723-732 Negative_regulation denotes inhibited
T13031 668-678 Gene_expression denotes production
T13030 699-703 Protein denotes CD4+
T13029 662-667 Protein denotes IFN-γ
T13028 654-657 Protein denotes Fig
T13027 608-618 Gene_expression denotes production
T13026 602-607 Protein denotes IFN-γ
T13025 578-583 Protein denotes IL-10
T13024 517-535 Protein denotes anti-CD28 antibody
T13023 495-512 Protein denotes anti-CD3 antibody
T13022 384-387 Protein denotes CD4
T13021 365-370 Protein denotes IL-10
T13020 346-352 Protein denotes RA CD4
T13019 220-230 Negative_regulation denotes inhibiting
T13018 220-230 Negative_regulation denotes inhibiting
T13017 265-272 Binding denotes binding
T13016 245-260 Phosphorylation denotes phosphorylation
T13015 236-244 Entity denotes tyrosine
T13014 276-305 Protein denotes phosphatidylinositol 3-kinase
T13013 231-235 Protein denotes CD28
T13012 74-78 Protein denotes CD28
T13011 20-30 Negative_regulation denotes inhibition
T13010 40-50 Gene_expression denotes production
T13009 0-10 Gene_expression denotes Resistance
T13008 54-69 Protein denotes RA CD4+ T cells
T13007 34-39 Protein denotes IFN-γ
T13006 14-19 Protein denotes IL-10
R6395 T13006 T13009 themeOf IL-10,Resistance
R6396 T13007 T13010 themeOf IFN-γ,production
R6397 T13010 T13011 themeOf production,inhibition
R6398 T13013 T13016 themeOf CD28,phosphorylation
R6399 T13013 T13015 partOf CD28,tyrosine
R6400 T13014 T13017 themeOf phosphatidylinositol 3-kinase,binding
R6401 T13015 T13016 Site tyrosine,phosphorylation
R6402 T13016 T13018 themeOf phosphorylation,inhibiting
R6403 T13017 T13019 themeOf binding,inhibiting
R6404 T13026 T13027 themeOf IFN-γ,production
R6405 T13029 T13031 themeOf IFN-γ,production
R6406 T13031 T13032 themeOf production,inhibited
R6407 T13034 T13036 themeOf IFN-γ,produce
R6408 T13037 T13043 themeOf IFN-γ,production
R6409 T13044 T13048 themeOf IFN-γ,production
R6410 T13045 T13049 themeOf Fig. 2a,production
R6411 T13046 T13050 themeOf IL-10,production
R6412 T13047 T13051 themeOf IFN-γ,production
R6413 T13060 T13061 themeOf IL-2,production
R6414 T13061 T13062 themeOf production,affected

test3

Id Subject Object Predicate Lexical cue
T12304 2299-2304 Protein denotes IL-10
T12303 2289-2295 Regulation denotes effect
T12302 2228-2231 Protein denotes CD4
T12301 2127-2134 Negative_regulation denotes reduced
T12300 2075-2083 Negative_regulation denotes decrease
T12299 2042-2047 Protein denotes IL-10
T12298 2022-2030 Regulation denotes affected
T12297 2003-2013 Gene_expression denotes production
T12296 1998-2002 Protein denotes IL-2
T12295 1934-1939 Protein denotes IL-10
T12294 1896-1900 Protein denotes CD28
T12293 1869-1872 Protein denotes CD4
T12292 1855-1865 Gene_expression denotes production
T12291 1850-1854 Protein denotes IL-2
T12290 1801-1804 Protein denotes CD4
T12289 1779-1784 Protein denotes IL-10
T12288 1746-1751 Protein denotes IFN-γ
T12287 1720-1728 Gene_expression denotes produced
T12286 1683-1686 Protein denotes CD4
T12285 1438-1448 Gene_expression denotes production
T12284 1432-1437 Protein denotes IFN-γ
T12283 1423-1428 Protein denotes IL-10
T12282 1413-1419 Regulation denotes effect
T12281 1352-1357 Protein denotes IL-10
T12280 1333-1343 Gene_expression denotes production
T12279 1327-1332 Protein denotes IFN-γ
T12278 1092-1097 Protein denotes IL-10
T12277 1046-1050 Protein denotes CD28
T12276 1038-1041 Protein denotes CD3
T12275 1019-1022 Protein denotes CD4
T12274 1005-1015 Gene_expression denotes production
T12273 999-1004 Protein denotes IFN-γ
T12272 932-937 Protein denotes IL-10
T12271 918-928 Negative_regulation denotes inhibition
T12270 878-883 Protein denotes IL-10
T12269 845-850 Protein denotes IFN-γ
T12268 814-821 Gene_expression denotes produce
T12267 788-791 Protein denotes CD4
T12266 769-774 Protein denotes IL-10
T12265 723-732 Negative_regulation denotes inhibited
T12264 699-702 Protein denotes CD4
T12263 668-678 Gene_expression denotes production
T12262 662-667 Protein denotes IFN-γ
T12261 608-618 Gene_expression denotes production
T12260 602-607 Protein denotes IFN-γ
T12259 578-583 Protein denotes IL-10
T12258 522-526 Protein denotes CD28
T12257 500-503 Protein denotes CD3
T12256 384-387 Protein denotes CD4
T12255 365-370 Protein denotes IL-10
T12254 349-352 Protein denotes CD4
T12253 265-272 Binding denotes binding
T12252 245-260 Phosphorylation denotes phosphorylation
T12251 231-235 Protein denotes CD28
T12250 220-230 Negative_regulation denotes inhibiting
T12249 175-180 Protein denotes IL-10
T12248 74-78 Protein denotes CD28
T12247 57-60 Protein denotes CD4
T12246 40-50 Gene_expression denotes production
T12245 34-39 Protein denotes IFN-γ
T12244 20-30 Negative_regulation denotes inhibition
T12243 14-19 Protein denotes IL-10
T12242 2299-2304 Protein denotes IL-10
T12241 2228-2231 Protein denotes CD4
T12240 2042-2047 Protein denotes IL-10
T12239 1998-2002 Protein denotes IL-2
T12238 1934-1939 Protein denotes IL-10
T12237 1896-1900 Protein denotes CD28
T12236 1869-1872 Protein denotes CD4
T12235 1850-1854 Protein denotes IL-2
T12234 1801-1804 Protein denotes CD4
T12233 1779-1784 Protein denotes IL-10
T12232 1746-1751 Protein denotes IFN-γ
T12231 1683-1686 Protein denotes CD4
T12230 1432-1437 Protein denotes IFN-γ
T12229 1423-1428 Protein denotes IL-10
T12228 1352-1357 Protein denotes IL-10
T12227 1327-1332 Protein denotes IFN-γ
T12226 1092-1097 Protein denotes IL-10
T12225 1046-1050 Protein denotes CD28
T12224 1038-1041 Protein denotes CD3
T12223 1019-1022 Protein denotes CD4
T12222 999-1004 Protein denotes IFN-γ
T12221 932-937 Protein denotes IL-10
T12220 878-883 Protein denotes IL-10
T12219 845-850 Protein denotes IFN-γ
T12218 788-791 Protein denotes CD4
T12217 769-774 Protein denotes IL-10
T12216 699-702 Protein denotes CD4
T12215 662-667 Protein denotes IFN-γ
T12214 602-607 Protein denotes IFN-γ
T12213 578-583 Protein denotes IL-10
T12212 522-526 Protein denotes CD28
T12211 500-503 Protein denotes CD3
T12210 384-387 Protein denotes CD4
T12209 365-370 Protein denotes IL-10
T12208 349-352 Protein denotes CD4
T12207 231-235 Protein denotes CD28
T12206 175-180 Protein denotes IL-10
T12205 74-78 Protein denotes CD28
T12204 57-60 Protein denotes CD4
T12203 34-39 Protein denotes IFN-γ
T12202 14-19 Protein denotes IL-10
R6330 T12243 T12244 causeOf IL-10,inhibition
R6331 T12245 T12246 themeOf IFN-γ,production
R6332 T12246 T12244 themeOf production,inhibition
R6333 T12249 T12250 causeOf IL-10,inhibiting
R6334 T12249 T12253 themeOf IL-10,binding
R6335 T12251 T12252 themeOf CD28,phosphorylation
R6336 T12252 T12250 themeOf phosphorylation,inhibiting
R6337 T12259 T12261 themeOf IL-10,production
R6338 T12260 T12261 themeOf IFN-γ,production
R6339 T12262 T12263 themeOf IFN-γ,production
R6340 T12263 T12265 themeOf production,inhibited
R6341 T12266 T12265 themeOf IL-10,inhibited
R6342 T12269 T12268 themeOf IFN-γ,produce
R6343 T12272 T12271 causeOf IL-10,inhibition
R6344 T12273 T12274 themeOf IFN-γ,production
R6345 T12279 T12280 themeOf IFN-γ,production
R6346 T12283 T12285 themeOf IL-10,production
R6347 T12284 T12285 themeOf IFN-γ,production
R6348 T12285 T12282 themeOf production,effect
R6349 T12288 T12287 themeOf IFN-γ,produced
R6350 T12291 T12292 themeOf IL-2,production
R6351 T12296 T12297 themeOf IL-2,production
R6352 T12297 T12300 themeOf production,decrease
R6353 T12297 T12301 themeOf production,reduced
R6354 T12297 T12298 themeOf production,affected
R6355 T12298 T12301 themeOf affected,reduced
R6356 T12299 T12298 causeOf IL-10,affected
R6357 T12300 T12298 causeOf decrease,affected
R6358 T12304 T12303 causeOf IL-10,effect

testone

Id Subject Object Predicate Lexical cue
T12174 2289-2295 Regulation denotes effect
T12173 2127-2134 Negative_regulation denotes reduced
T12172 2075-2083 Negative_regulation denotes decrease
T12171 2022-2030 Regulation denotes affected
T12170 2003-2013 Gene_expression denotes production
T12169 1855-1865 Gene_expression denotes production
T12168 1729-1735 Positive_regulation denotes higher
T12167 1720-1728 Gene_expression denotes produced
T12166 1467-1474 Negative_regulation denotes limited
T12165 1438-1448 Gene_expression denotes production
T12164 1413-1419 Regulation denotes effect
T12163 1402-1412 Negative_regulation denotes inhibitory
T12162 1333-1343 Gene_expression denotes production
T12161 1005-1015 Gene_expression denotes production
T12160 918-928 Negative_regulation denotes inhibition
T12159 814-821 Gene_expression denotes produce
T12158 723-732 Negative_regulation denotes inhibited
T12157 668-678 Gene_expression denotes production
T12156 608-618 Gene_expression denotes production
T12155 40-50 Gene_expression denotes production
T12154 20-30 Negative_regulation denotes inhibition
T12153 2299-2304 Protein denotes IL-10
T12152 2228-2231 Protein denotes CD4
T12151 2042-2047 Protein denotes IL-10
T12150 1998-2002 Protein denotes IL-2
T12149 1934-1939 Protein denotes IL-10
T12148 1896-1900 Protein denotes CD28
T12147 1869-1872 Protein denotes CD4
T12146 1850-1854 Protein denotes IL-2
T12145 1801-1804 Protein denotes CD4
T12144 1779-1784 Protein denotes IL-10
T12143 1746-1751 Protein denotes IFN-γ
T12142 1683-1686 Protein denotes CD4
T12141 1432-1437 Protein denotes IFN-γ
T12140 1423-1428 Protein denotes IL-10
T12139 1352-1357 Protein denotes IL-10
T12138 1327-1332 Protein denotes IFN-γ
T12137 1092-1097 Protein denotes IL-10
T12136 1046-1050 Protein denotes CD28
T12135 1038-1041 Protein denotes CD3
T12134 1019-1022 Protein denotes CD4
T12133 999-1004 Protein denotes IFN-γ
T12132 932-937 Protein denotes IL-10
T12131 878-883 Protein denotes IL-10
T12130 845-850 Protein denotes IFN-γ
T12129 788-791 Protein denotes CD4
T12128 769-774 Protein denotes IL-10
T12127 699-702 Protein denotes CD4
T12126 662-667 Protein denotes IFN-γ
T12125 602-607 Protein denotes IFN-γ
T12124 578-583 Protein denotes IL-10
T12123 522-526 Protein denotes CD28
T12122 500-503 Protein denotes CD3
T12121 384-387 Protein denotes CD4
T12120 365-370 Protein denotes IL-10
T12119 349-352 Protein denotes CD4
T12118 231-235 Protein denotes CD28
T12117 175-180 Protein denotes IL-10
T12116 74-78 Protein denotes CD28
T12115 57-60 Protein denotes CD4
T12114 34-39 Protein denotes IFN-γ
T12113 14-19 Protein denotes IL-10
R6304 T12113 T12154 causeOf IL-10,inhibition
R6305 T12114 T12155 themeOf IFN-γ,production
R6306 T12124 T12156 themeOf IL-10,production
R6307 T12125 T12156 themeOf IFN-γ,production
R6308 T12126 T12157 themeOf IFN-γ,production
R6309 T12130 T12159 themeOf IFN-γ,produce
R6310 T12132 T12160 causeOf IL-10,inhibition
R6311 T12133 T12161 themeOf IFN-γ,production
R6312 T12138 T12162 themeOf IFN-γ,production
R6313 T12141 T12165 themeOf IFN-γ,production
R6314 T12143 T12167 themeOf IFN-γ,produced
R6315 T12143 T12168 themeOf IFN-γ,higher
R6316 T12144 T12168 causeOf IL-10,higher
R6317 T12146 T12169 themeOf IL-2,production
R6318 T12150 T12170 themeOf IL-2,production
R6319 T12151 T12171 causeOf IL-10,affected
R6320 T12153 T12174 themeOf IL-10,effect
R6321 T12155 T12154 themeOf production,inhibition
R6322 T12157 T12158 themeOf production,inhibited
R6323 T12165 T12166 themeOf production,limited
R6324 T12165 T12164 themeOf production,effect
R6325 T12167 T12168 themeOf produced,higher
R6326 T12170 T12172 themeOf production,decrease
R6327 T12170 T12173 themeOf production,reduced
R6328 T12170 T12171 themeOf production,affected
R6329 T12172 T12171 causeOf decrease,affected