CORD-19:11372d2b62ec98cab9cf3f9be6b7cf967627a14a / 0-628 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/CORD-19/sourceid/11372d2b62ec98cab9cf3f9be6b7cf967627a14a","sourcedb":"CORD-19","sourceid":"11372d2b62ec98cab9cf3f9be6b7cf967627a14a","text":"CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection\n\nAbstract\nGraphical Abstract Highlights d Deficiency of CARMA3 results in the host resistance to RNA viral infection d CARMA3 positively regulates RIG-I/MAVS-mediated NF-kB activation d CARMA3 negatively regulates RIG-I/MAVS-mediated TBK1/ IRF3 activation d CARMA3 negatively suppresses MAVS oligomerization in mitochondran SUMMARY Host response to RNA virus infection is sensed by RNA sensors such as RIG-I, which induces MAVSmediated NF-kB and IRF3 activation to promote inflammatory and antiviral responses, respec","tracks":[{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T1","span":{"begin":0,"end":110},"obj":"Sentence"},{"id":"T2","span":{"begin":112,"end":120},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"CORD-19_Custom_license_subset"},{"subj":"T2","pred":"source","obj":"CORD-19_Custom_license_subset"}]},{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":110},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":112,"end":120},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T1","pred":"source","obj":"CORD-19-Sentences"},{"subj":"TextSentencer_T2","pred":"source","obj":"CORD-19-Sentences"}]},{"project":"CORD-19-PD-MONDO","denotations":[{"id":"T1","span":{"begin":95,"end":110},"obj":"Disease"},{"id":"T2","span":{"begin":101,"end":110},"obj":"Disease"},{"id":"T3","span":{"begin":212,"end":227},"obj":"Disease"},{"id":"T4","span":{"begin":218,"end":227},"obj":"Disease"},{"id":"T5","span":{"begin":464,"end":479},"obj":"Disease"},{"id":"T6","span":{"begin":470,"end":479},"obj":"Disease"},{"id":"T5770","span":{"begin":95,"end":110},"obj":"Disease"},{"id":"T8980","span":{"begin":101,"end":110},"obj":"Disease"},{"id":"T53412","span":{"begin":212,"end":227},"obj":"Disease"},{"id":"T70620","span":{"begin":218,"end":227},"obj":"Disease"},{"id":"T88410","span":{"begin":464,"end":479},"obj":"Disease"},{"id":"T78357","span":{"begin":470,"end":479},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A66226","pred":"mondo_id","subj":"T5770","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A57865","pred":"mondo_id","subj":"T8980","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A24497","pred":"mondo_id","subj":"T53412","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A37121","pred":"mondo_id","subj":"T70620","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A59132","pred":"mondo_id","subj":"T88410","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A3114","pred":"mondo_id","subj":"T78357","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"subj":"T1","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T2","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T3","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T4","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T5","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T6","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T5770","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T8980","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T53412","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T70620","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T88410","pred":"source","obj":"CORD-19-PD-MONDO"},{"subj":"T78357","pred":"source","obj":"CORD-19-PD-MONDO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"CORD-19_Custom_license_subset","color":"#93ecbd","default":true},{"id":"CORD-19-Sentences","color":"#eca393"},{"id":"CORD-19-PD-MONDO","color":"#939cec"}]}]}}