BB-norm+ner@ldeleger:BB-norm+ner-18789156 / 1809-2536
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bionlp-ost-19-BB-norm-ner-dev
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| Id | Subject | Object | Predicate | Lexical cue | NCBI_Taxonomy | OntoBiotope |
|---|---|---|---|---|---|---|
| T4 | 0-727 | Paragraph | denotes | Altogether, our results demonstrate that the interaction between surface nucleolin and its bacterial ligand EF-Tu plays an important role in Francisella tularensis adhesion and entry process and may therefore facilitate invasion of host tissues. Since phagosomal escape and intra-cytosolic multiplication of LVS in infected monocytes are very similar to those of human pathogenic F. tularensis ssp tularensis, the mechanism of entry into monocyte-like THP-1 cells, involving interaction between EF-Tu and nucleolin, might be similar in the two subspecies. Thus, the use of either nucleolin-specific pseudopeptide HB-19 or recombinant EF-Tu could provide attractive therapeutic approaches for modulating F. tularensis infection. | ||
| T33 | 141-163 | Microorganism | denotes | Francisella tularensis | 263 | |
| T34 | 164-172 | Phenotype | denotes | adhesion | OBT:000029 | |
| T35 | 220-244 | Phenotype | denotes | invasion of host tissues | OBT:002806 | |
| T36 | 232-244 | Habitat | denotes | host tissues | OBT:000196 | |
| T37 | 308-311 | Microorganism | denotes | LVS | 263 | |
| T38 | 315-333 | Habitat | denotes | infected monocytes | OBT:003001 | |
| T40 | 363-379 | Phenotype | denotes | human pathogenic | OBT:002806 | |
| T39 | 363-368 | Habitat | denotes | human | OBT:002488 | |
| T41 | 380-408 | Microorganism | denotes | F. tularensis ssp tularensis | 119856 | |
| T42 | 438-463 | Habitat | denotes | monocyte-like THP-1 cells | OBT:003001|OBT:000062 | |
| T43 | 703-716 | Microorganism | denotes | F. tularensis | 263 |