PubMed:9929979 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/9929979","sourcedb":"PubMed","sourceid":"9929979","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/9929979","text":"Molecular cloning, mapping, and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-associated gene, MTA1.\nThrough large-scale sequencing of clones randomly selected from libraries of human cDNAs, we have isolated a novel human gene encoding a product with 59.6% identity in amino acid sequence to human MTA1, a protein associated with tumor invasion and metastasis. This cDNA, named MTA1-L1 (MTA1 like 1), consists of 2736 nucleotides with an open reading frame encoding 668 amino acids. A single 3.0-kb transcript of MTA1-L1 was expressed ubiquitously on Northern blots. Structural analysis of the MTA1-L1 gene revealed 18 exons spanning 8.1 kb of genomic DNA. We assigned the MTA1-L1 locus to chromosomal band 11q12-13.1 by fluorescence in situ hybridization.","tracks":[{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":72,"end":79},"obj":"gene:9219"},{"id":"T1","span":{"begin":103,"end":113},"obj":"disease:C0027627"},{"id":"T2","span":{"begin":72,"end":79},"obj":"gene:9219"},{"id":"T3","span":{"begin":103,"end":113},"obj":"disease:C2939420"},{"id":"T4","span":{"begin":334,"end":338},"obj":"gene:9112"},{"id":"T5","span":{"begin":385,"end":395},"obj":"disease:C0027627"},{"id":"T6","span":{"begin":334,"end":338},"obj":"gene:9112"},{"id":"T7","span":{"begin":385,"end":395},"obj":"disease:C2939420"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"},{"id":"R4","pred":"associated_with","subj":"T6","obj":"T7"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"},{"subj":"T2","pred":"source","obj":"DisGeNET"},{"subj":"T3","pred":"source","obj":"DisGeNET"},{"subj":"T4","pred":"source","obj":"DisGeNET"},{"subj":"T5","pred":"source","obj":"DisGeNET"},{"subj":"T6","pred":"source","obj":"DisGeNET"},{"subj":"T7","pred":"source","obj":"DisGeNET"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"DisGeNET","color":"#ec93a7","default":true}]}]}}