PubMed:9928552
Annnotations
UseCases_ArguminSci_Discourse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-92 | DRI_Background | denotes | Ductal carcinoma in situ of the breast: histological classification and genetic alterations. |
| T2 | 93-287 | DRI_Background | denotes | Ductal carcinoma in situ (DCIS) of the breast represents a proliferation of malignant epithelial cells within the ducts and lobules of the breast, without invasion through the basement membrane. |
| T3 | 288-473 | DRI_Background | denotes | It is believed that all invasive carcinomas are preceded by DCIS; however, it is not known what proportion of patients with DCIS will develop invasive carcinoma and after what interval. |
| T4 | 474-589 | DRI_Outcome | denotes | DCIS is heterogeneous with respect to its clinical presentation, mammographic abnormalities, histology and biology. |
| T5 | 590-836 | DRI_Approach | denotes | The risk of progression to invasive carcinoma depends on the histologic type of DCIS and the size of the lesion; in the future, the analysis of the genetic alterations may also help in predicting the risk of progression to invasive breast cancer. |
| T6 | 837-1066 | DRI_Approach | denotes | As the risk of progression to invasive breast cancer (and the development of metastases) greatly influences the choice of treatment for DCIS, it is of importance to be able to make a reliable estimate of this risk of progression. |
| T7 | 1067-1193 | DRI_Outcome | denotes | In this chapter, the histologic classification of DCIS and the genetic alterations that have been found to date are discussed. |
c_corpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 0-24 | D002285 | denotes | Ductal carcinoma in situ |
| T4 | 0-24 | D002285 | denotes | Ductal carcinoma in situ |
| T9 | 32-38 | UBERON:0000310 | denotes | breast |
| T12 | 100-117 | D002278 | denotes | carcinoma in situ |
| T13 | 100-117 | D002278 | denotes | carcinoma in situ |
| T15 | 119-123 | CVCL_5552 | denotes | DCIS |
| T14 | 119-123 | D002285 | denotes | DCIS |
| T16 | 119-123 | D002285 | denotes | DCIS |
| T17 | 132-138 | UBERON:0000310 | denotes | breast |
| T18 | 152-165 | UBERON:2000098 | denotes | proliferation |
| T19 | 207-212 | UBERON:0000058 | denotes | ducts |
| T20 | 232-238 | UBERON:0000310 | denotes | breast |
| T22 | 269-286 | UBERON:0005769 | denotes | basement membrane |
| T21 | 269-286 | GO:0005604 | denotes | basement membrane |
| T26 | 321-331 | D002277 | denotes | carcinomas |
| T27 | 321-331 | D002277 | denotes | carcinomas |
| T29 | 348-352 | CVCL_5552 | denotes | DCIS |
| T28 | 348-352 | D002285 | denotes | DCIS |
| T30 | 348-352 | D002285 | denotes | DCIS |
| T32 | 412-416 | CVCL_5552 | denotes | DCIS |
| T31 | 412-416 | D002285 | denotes | DCIS |
| T33 | 412-416 | D002285 | denotes | DCIS |
| T34 | 439-448 | D002277 | denotes | carcinoma |
| T35 | 439-448 | D002277 | denotes | carcinoma |
| T37 | 474-478 | CVCL_5552 | denotes | DCIS |
| T36 | 474-478 | D002285 | denotes | DCIS |
| T38 | 474-478 | D002285 | denotes | DCIS |
| T39 | 626-635 | D002277 | denotes | carcinoma |
| T40 | 626-635 | D002277 | denotes | carcinoma |
| T42 | 670-674 | CVCL_5552 | denotes | DCIS |
| T41 | 670-674 | D002285 | denotes | DCIS |
| T43 | 670-674 | D002285 | denotes | DCIS |
| T44 | 822-828 | UBERON:0000310 | denotes | breast |
| T45 | 822-835 | D001943 | denotes | breast cancer |
| T46 | 822-835 | D001943 | denotes | breast cancer |
| T47 | 876-882 | UBERON:0000310 | denotes | breast |
| T48 | 876-889 | D001943 | denotes | breast cancer |
| T49 | 876-889 | D001943 | denotes | breast cancer |
| T50 | 914-924 | D009362 | denotes | metastases |
| T51 | 914-924 | D009362 | denotes | metastases |
| T53 | 973-977 | CVCL_5552 | denotes | DCIS |
| T52 | 973-977 | D002285 | denotes | DCIS |
| T54 | 973-977 | D002285 | denotes | DCIS |
| T56 | 1117-1121 | CVCL_5552 | denotes | DCIS |
| T55 | 1117-1121 | D002285 | denotes | DCIS |
| T57 | 1117-1121 | D002285 | denotes | DCIS |