PubMed:9915850 / 1562-1863 JSONTXT

{"project":"sentences","denotations":[{"id":"T10","span":{"begin":0,"end":301},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}

{"project":"jnlpba-st-training","denotations":[{"id":"T43","span":{"begin":18,"end":22},"obj":"protein"},{"id":"T44","span":{"begin":35,"end":39},"obj":"protein"},{"id":"T45","span":{"begin":43,"end":47},"obj":"protein"},{"id":"T46","span":{"begin":137,"end":140},"obj":"protein"},{"id":"T47","span":{"begin":145,"end":148},"obj":"protein"},{"id":"T48","span":{"begin":153,"end":157},"obj":"protein"},{"id":"T49","span":{"begin":223,"end":236},"obj":"protein"},{"id":"T50","span":{"begin":241,"end":289},"obj":"protein"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}

{"project":"FSU-PRGE","denotations":[{"id":"T40","span":{"begin":18,"end":22},"obj":"protein"},{"id":"T41","span":{"begin":35,"end":39},"obj":"protein"},{"id":"T42","span":{"begin":43,"end":47},"obj":"protein"},{"id":"T43","span":{"begin":137,"end":140},"obj":"protein"},{"id":"T44","span":{"begin":145,"end":148},"obj":"protein"},{"id":"T45","span":{"begin":153,"end":157},"obj":"protein"},{"id":"T46","span":{"begin":223,"end":236},"obj":"protein"},{"id":"T47","span":{"begin":241,"end":289},"obj":"protein"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}

{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S10","span":{"begin":0,"end":301},"obj":"Sentence"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}

{"project":"genia-medco-coref","denotations":[{"id":"C31","span":{"begin":18,"end":22},"obj":"NP"},{"id":"C32","span":{"begin":35,"end":47},"obj":"NP"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}

{"project":"GENIAcorpus","denotations":[{"id":"T52","span":{"begin":18,"end":22},"obj":"protein_molecule"},{"id":"T53","span":{"begin":35,"end":39},"obj":"protein_molecule"},{"id":"T54","span":{"begin":43,"end":47},"obj":"protein_molecule"},{"id":"T55","span":{"begin":109,"end":117},"obj":"amino_acid_monomer"},{"id":"T56","span":{"begin":137,"end":140},"obj":"protein_molecule"},{"id":"T57","span":{"begin":145,"end":148},"obj":"protein_molecule"},{"id":"T58","span":{"begin":153,"end":157},"obj":"protein_family_or_group"},{"id":"T59","span":{"begin":223,"end":236},"obj":"protein_molecule"},{"id":"T60","span":{"begin":241,"end":289},"obj":"protein_molecule"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T4","span":{"begin":241,"end":252},"obj":"Body_part"},{"id":"T5","span":{"begin":253,"end":263},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CL_0000094"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CL_0000235"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}

{"project":"CL-cell","denotations":[{"id":"T7","span":{"begin":241,"end":252},"obj":"Cell"},{"id":"T8","span":{"begin":253,"end":263},"obj":"Cell"}],"attributes":[{"id":"A7","pred":"cl_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CL:0000094"},{"id":"A8","pred":"cl_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CL:0000235"},{"id":"A9","pred":"cl_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CL:0000394"}],"text":"Thus, ligation of CD28 with either CD80 or CD86 leads to shared early signal transduction events such as the tyrosine phosphorylation of CBL and VAV, to NFAT-mediated transcriptional activation, and to the costimulation of interleukin-2 and granulocyte-macrophage colony-stimulating factor production."}