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PubMed:9858638 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 80-95 https://glytoucan.org/Structures/Glycans/G00065MO denotes Polysialic acid

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 80-95 Glycan_Motif denotes Polysialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T2 97-100 Glycan_Motif denotes PSA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T3 218-221 Glycan_Motif denotes PSA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T4 1419-1422 Glycan_Motif denotes PSA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T5 1483-1486 Glycan_Motif denotes PSA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T6 1519-1522 Glycan_Motif denotes PSA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T7 1590-1593 Glycan_Motif denotes PSA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-79 Sentence denotes Genomic organization of the murine polysialyltransferase gene ST8SiaIV (PST-1).
TextSentencer_T2 80-153 Sentence denotes Polysialic acid (PSA) is an important regulator of cellular interactions.
TextSentencer_T3 154-222 Sentence denotes Two enzymes (ST8SiaII and ST8SiaIV) are capable of synthesizing PSA.
TextSentencer_T4 223-327 Sentence denotes In the present study, the gene encoding the murine ST8SiaIV (PST-1) has been isolated and characterized.
TextSentencer_T5 328-488 Sentence denotes In contrast to the ST8SiaII (STX) gene which contains six exons and spans about 80 kb, the ST8SiaIV gene comprises only five exons spanning over at least 55 kb.
TextSentencer_T6 489-644 Sentence denotes However, alignment of the two genes revealed that exon-intron boundaries of exons 2-5 of ST8SiaIV and exons 3-6 of ST8SiaII are located at identical sites.
TextSentencer_T7 645-816 Sentence denotes Differences are restricted to the 5'-region encoded by one exon in the case of ST8SiaIV, whereas the corresponding region of ST8SiaII is interrupted by a very long intron.
TextSentencer_T8 817-997 Sentence denotes 5'-RACE analysis of the ST8SiaIV transcript using mRNA from AtT20 cells identified two transcription start sites at positions -324 and -204 relative to the translation start codon.
TextSentencer_T9 998-1095 Sentence denotes The promoter region of ST8SiaIV lacks TATA- and CAAT-like sequences and is enriched in G+C (60%).
TextSentencer_T10 1096-1218 Sentence denotes The promoter contains putative Sp1, AP-1, AP-2, and PEA3 binding sites, as well as a purine- and a pyrimidine-rich region.
TextSentencer_T11 1219-1354 Sentence denotes Luciferase reporter gene assays demonstrated that the region between nucleotides -443 and -162 is sufficient to direct gene expression.
TextSentencer_T12 1355-1549 Sentence denotes The induction of luciferase activity was 30- and 10-fold in the PSA-positive AtT20 and CHO cells, but only 5- and 7-fold in the PSA-negative NIH-3T3 cells and in a PSA-negative subline of AtT20.
TextSentencer_T13 1550-1792 Sentence denotes Thus, although decreased in activity in PSA-negative cell lines, the basal promoter is not sufficient for the strong cell-type and tissue specific regulation of the ST8SiaIV gene, suggesting regulatory elements in the more upstream 5'-region.
T1 0-79 Sentence denotes Genomic organization of the murine polysialyltransferase gene ST8SiaIV (PST-1).
T2 80-153 Sentence denotes Polysialic acid (PSA) is an important regulator of cellular interactions.
T3 154-222 Sentence denotes Two enzymes (ST8SiaII and ST8SiaIV) are capable of synthesizing PSA.
T4 223-327 Sentence denotes In the present study, the gene encoding the murine ST8SiaIV (PST-1) has been isolated and characterized.
T5 328-488 Sentence denotes In contrast to the ST8SiaII (STX) gene which contains six exons and spans about 80 kb, the ST8SiaIV gene comprises only five exons spanning over at least 55 kb.
T6 489-644 Sentence denotes However, alignment of the two genes revealed that exon-intron boundaries of exons 2-5 of ST8SiaIV and exons 3-6 of ST8SiaII are located at identical sites.
T7 645-816 Sentence denotes Differences are restricted to the 5'-region encoded by one exon in the case of ST8SiaIV, whereas the corresponding region of ST8SiaII is interrupted by a very long intron.
T8 817-997 Sentence denotes 5'-RACE analysis of the ST8SiaIV transcript using mRNA from AtT20 cells identified two transcription start sites at positions -324 and -204 relative to the translation start codon.
T9 998-1095 Sentence denotes The promoter region of ST8SiaIV lacks TATA- and CAAT-like sequences and is enriched in G+C (60%).
T10 1096-1218 Sentence denotes The promoter contains putative Sp1, AP-1, AP-2, and PEA3 binding sites, as well as a purine- and a pyrimidine-rich region.
T11 1219-1354 Sentence denotes Luciferase reporter gene assays demonstrated that the region between nucleotides -443 and -162 is sufficient to direct gene expression.
T12 1355-1549 Sentence denotes The induction of luciferase activity was 30- and 10-fold in the PSA-positive AtT20 and CHO cells, but only 5- and 7-fold in the PSA-negative NIH-3T3 cells and in a PSA-negative subline of AtT20.
T13 1550-1792 Sentence denotes Thus, although decreased in activity in PSA-negative cell lines, the basal promoter is not sufficient for the strong cell-type and tissue specific regulation of the ST8SiaIV gene, suggesting regulatory elements in the more upstream 5'-region.
T1 0-79 Sentence denotes Genomic organization of the murine polysialyltransferase gene ST8SiaIV (PST-1).
T2 80-153 Sentence denotes Polysialic acid (PSA) is an important regulator of cellular interactions.
T3 154-222 Sentence denotes Two enzymes (ST8SiaII and ST8SiaIV) are capable of synthesizing PSA.
T4 223-327 Sentence denotes In the present study, the gene encoding the murine ST8SiaIV (PST-1) has been isolated and characterized.
T5 328-488 Sentence denotes In contrast to the ST8SiaII (STX) gene which contains six exons and spans about 80 kb, the ST8SiaIV gene comprises only five exons spanning over at least 55 kb.
T6 489-644 Sentence denotes However, alignment of the two genes revealed that exon-intron boundaries of exons 2-5 of ST8SiaIV and exons 3-6 of ST8SiaII are located at identical sites.
T7 645-816 Sentence denotes Differences are restricted to the 5'-region encoded by one exon in the case of ST8SiaIV, whereas the corresponding region of ST8SiaII is interrupted by a very long intron.
T8 817-997 Sentence denotes 5'-RACE analysis of the ST8SiaIV transcript using mRNA from AtT20 cells identified two transcription start sites at positions -324 and -204 relative to the translation start codon.
T9 998-1095 Sentence denotes The promoter region of ST8SiaIV lacks TATA- and CAAT-like sequences and is enriched in G+C (60%).
T10 1096-1218 Sentence denotes The promoter contains putative Sp1, AP-1, AP-2, and PEA3 binding sites, as well as a purine- and a pyrimidine-rich region.
T11 1219-1354 Sentence denotes Luciferase reporter gene assays demonstrated that the region between nucleotides -443 and -162 is sufficient to direct gene expression.
T12 1355-1549 Sentence denotes The induction of luciferase activity was 30- and 10-fold in the PSA-positive AtT20 and CHO cells, but only 5- and 7-fold in the PSA-negative NIH-3T3 cells and in a PSA-negative subline of AtT20.
T13 1550-1792 Sentence denotes Thus, although decreased in activity in PSA-negative cell lines, the basal promoter is not sufficient for the strong cell-type and tissue specific regulation of the ST8SiaIV gene, suggesting regulatory elements in the more upstream 5'-region.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 80-95 https://glytoucan.org/Structures/Glycans/G00065MO denotes Polysialic acid

GlycoBiology-cGGDB

Id Subject Object Predicate Lexical cue
_T1 72-77 http://jcggdb.jp/cggdb/entry.action?jcg_id=JCEG149 denotes PST-1
_T2 284-289 http://jcggdb.jp/cggdb/entry.action?jcg_id=JCEG149 denotes PST-1

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 0-7 FMAID:84116 denotes Genomic
_T2 0-7 FMAID:198062 denotes Genomic
_T3 8-20 FMAID:166081 denotes organization
_T4 8-20 FMAID:67498 denotes organization
_T5 57-61 FMAID:198663 denotes gene
_T6 249-253 FMAID:198663 denotes gene
_T7 362-366 FMAID:198663 denotes gene
_T8 386-391 FMAID:84120 denotes exons
_T9 386-391 FMAID:198073 denotes exons
_T10 428-432 FMAID:198663 denotes gene
_T11 453-458 FMAID:198073 denotes exons
_T12 453-458 FMAID:84120 denotes exons
_T13 519-524 FMAID:198663 denotes genes
_T14 539-543 FMAID:198073 denotes exon
_T15 539-543 FMAID:84120 denotes exon
_T16 544-550 FMAID:84121 denotes intron
_T17 544-550 FMAID:198075 denotes intron
_T18 565-570 FMAID:198073 denotes exons
_T19 565-570 FMAID:84120 denotes exons
_T20 591-596 FMAID:84120 denotes exons
_T21 591-596 FMAID:198073 denotes exons
_T22 704-708 FMAID:84120 denotes exon
_T23 704-708 FMAID:198073 denotes exon
_T24 809-815 FMAID:84121 denotes intron
_T25 809-815 FMAID:198075 denotes intron
_T26 883-888 FMAID:169002 denotes cells
_T27 883-888 FMAID:68646 denotes cells
_T28 1181-1187 FMAID:196765 denotes purine
_T29 1181-1187 FMAID:82772 denotes purine
_T30 1195-1205 FMAID:82773 denotes pyrimidine
_T31 1195-1205 FMAID:196766 denotes pyrimidine
_T32 1239-1243 FMAID:198663 denotes gene
_T33 1288-1299 FMAID:196729 denotes nucleotides
_T34 1288-1299 FMAID:82740 denotes nucleotides
_T35 1338-1342 FMAID:198663 denotes gene
_T36 1446-1451 FMAID:169002 denotes cells
_T37 1446-1451 FMAID:68646 denotes cells
_T38 1504-1509 FMAID:169002 denotes cells
_T39 1504-1509 FMAID:68646 denotes cells
_T40 1619-1624 FMAID:179279 denotes basal
_T41 1619-1624 FMAID:74542 denotes basal
_T42 1681-1687 FMAID:256050 denotes tissue
_T43 1724-1728 FMAID:198663 denotes gene

uniprot-human

Id Subject Object Predicate Lexical cue
T1 62-70 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T2 180-188 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T3 274-282 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T4 419-427 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T5 578-586 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T6 724-732 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T7 841-849 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T8 1021-1029 http://www.uniprot.org/uniprot/Q92187 denotes ST8SiaIV
T9 72-75 http://www.uniprot.org/uniprot/Q92187 denotes PST
T10 284-287 http://www.uniprot.org/uniprot/Q92187 denotes PST
T11 97-100 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T12 218-221 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T13 1419-1422 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T14 1483-1486 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T15 1519-1522 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T16 1590-1593 http://www.uniprot.org/uniprot/Q9Y617 denotes PSA
T17 97-100 http://www.uniprot.org/uniprot/P55786 denotes PSA
T18 218-221 http://www.uniprot.org/uniprot/P55786 denotes PSA
T19 1419-1422 http://www.uniprot.org/uniprot/P55786 denotes PSA
T20 1483-1486 http://www.uniprot.org/uniprot/P55786 denotes PSA
T21 1519-1522 http://www.uniprot.org/uniprot/P55786 denotes PSA
T22 1590-1593 http://www.uniprot.org/uniprot/P55786 denotes PSA
T23 97-100 http://www.uniprot.org/uniprot/P07288 denotes PSA
T24 218-221 http://www.uniprot.org/uniprot/P07288 denotes PSA
T25 1419-1422 http://www.uniprot.org/uniprot/P07288 denotes PSA
T26 1483-1486 http://www.uniprot.org/uniprot/P07288 denotes PSA
T27 1519-1522 http://www.uniprot.org/uniprot/P07288 denotes PSA
T28 1590-1593 http://www.uniprot.org/uniprot/P07288 denotes PSA
T29 167-175 http://www.uniprot.org/uniprot/Q92186 denotes ST8SiaII
T30 347-355 http://www.uniprot.org/uniprot/Q92186 denotes ST8SiaII
T31 604-612 http://www.uniprot.org/uniprot/Q92186 denotes ST8SiaII
T32 357-360 http://www.uniprot.org/uniprot/Q92186 denotes STX
T33 1138-1142 http://www.uniprot.org/uniprot/P05549 denotes AP-2
T34 1148-1152 http://www.uniprot.org/uniprot/P43268 denotes PEA3

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 62-70 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T2 180-188 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T3 274-282 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T4 419-427 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T5 578-586 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T6 724-732 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T7 841-849 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T8 1021-1029 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T9 1715-1723 http://www.uniprot.org/uniprot/Q64692 denotes ST8SiaIV
T10 97-100 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T11 218-221 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T12 1419-1422 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T13 1483-1486 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T14 1519-1522 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T15 1590-1593 http://www.uniprot.org/uniprot/Q11011 denotes PSA
T16 167-175 http://www.uniprot.org/uniprot/O35696 denotes ST8SiaII
T17 347-355 http://www.uniprot.org/uniprot/O35696 denotes ST8SiaII
T18 604-612 http://www.uniprot.org/uniprot/O35696 denotes ST8SiaII
T19 357-360 http://www.uniprot.org/uniprot/O35696 denotes STX
T20 1127-1130 http://www.uniprot.org/uniprot/Q76LW6 denotes Sp1
T21 1127-1130 http://www.uniprot.org/uniprot/O89090 denotes Sp1
T22 1132-1136 http://www.uniprot.org/uniprot/P05627 denotes AP-1
T23 1138-1142 http://www.uniprot.org/uniprot/Q91VX0 denotes AP-2
T24 1148-1152 http://www.uniprot.org/uniprot/P28322 denotes PEA3

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 883-888 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T2 991-996 http://purl.bioontology.org/ontology/NCBITAXON/722432 denotes codon
T3 991-996 http://purl.bioontology.org/ontology/NCBITAXON/79338 denotes codon
T4 1446-1451 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T5 1504-1509 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T6 1681-1687 http://purl.bioontology.org/ontology/STY/T024 denotes tissue

GO-BP

Id Subject Object Predicate Lexical cue
T1 72-75 http://purl.obolibrary.org/obo/GO_0004062 denotes PST
T2 284-287 http://purl.obolibrary.org/obo/GO_0004062 denotes PST
T3 118-127 http://purl.obolibrary.org/obo/GO_0065007 denotes regulator
T4 1697-1707 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T5 131-139 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T6 850-860 http://purl.obolibrary.org/obo/GO_0006351 denotes transcript
T7 904-917 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T8 973-984 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T9 1338-1353 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T10 1372-1391 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activity
T11 1372-1391 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activity
T12 1372-1391 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activity
T13 1372-1391 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activity
T14 1372-1391 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activity
T15 1442-1445 http://purl.obolibrary.org/obo/GO_0043848 denotes CHO

GO-MF

Id Subject Object Predicate Lexical cue
T1 1153-1160 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T2 1153-1160 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T3 1153-1160 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T4 1153-1160 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

GO-CC

Id Subject Object Predicate Lexical cue
T1 883-888 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 1446-1451 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 1504-1509 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 1603-1607 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5 1667-1671 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 1681-1687 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 97-100 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T2 218-221 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T3 1419-1422 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T4 1483-1486 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T5 1519-1522 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA
Lectin_T6 1590-1593 https://acgg.asia/db/lfdb/LfDB0181 denotes PSA

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1681-1687 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T2 8-20 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organization

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1681-1687 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

Glycosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 1619-1624 Cell denotes basal http://purl.obolibrary.org/obo/CL:0002324