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PubMed:9857011 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 18-37 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T2 41-47 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T3 178-197 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T4 235-254 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T5 343-346 Glycan_Motif denotes Lex https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC
T6 353-373 Glycan_Motif denotes N-acetyllactosamines https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T7 415-421 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T8 474-480 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T9 681-700 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T10 755-761 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T11 895-914 Glycan_Motif denotes N-acetylglucosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G64581RP
T12 1206-1215 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T14 1386-1405 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T15 1409-1415 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T16 1514-1533 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T17 1672-1691 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T18 1731-1737 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T19 1788-1808 Glycan_Motif denotes N-acetyllactosamines https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T20 1917-1936 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T21 1950-1956 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO

sentences

Id Subject Object Predicate Lexical cue
T1 0-67 Sentence denotes Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans.
T2 68-172 Sentence denotes The requirement of novel beta-1,4-galactosyltransferase IV and beta-1,3-n-acetylglucosaminyltransferase.
T3 173-347 Sentence denotes Poly-N-acetyllactosamine is a unique carbohydrate composed of N-acetyllactosamine repeats and provides the backbone structure for additional modifications such as sialyl Lex.
T4 348-522 Sentence denotes Poly-N-acetyllactosamines in mucin-type O-glycans can be formed in core 2 branched oligosaccharides, which are synthesized by core 2 beta-1,6-N-acetylglucosaminyltransferase.
T5 523-833 Sentence denotes Using a beta-1, 4-galactosyltransferase (beta4Gal-TI) present in milk and the recently cloned beta-1,3-N-acetylglucosaminyltransferase, the formation of poly-N-acetyllactosamine was found to be extremely inefficient starting from a core 2 branched oligosaccharide, GlcNAcbeta1-->6(Galbeta1-->3)GalNAcalpha-->R.
T6 834-1070 Sentence denotes Since the majority of synthesized oligosaccharides contained N-acetylglucosamine at the nonreducing ends, galactosylation was judged to be inefficient, prompting us to test novel members of the beta4Gal-T gene family for this synthesis.
T7 1071-1272 Sentence denotes Using various synthetic acceptors and recombinant beta4Gal-Ts, beta4Gal-TIV was found to be most efficient in the addition of a single galactose residue to GlcNAcbeta1-->6(Galbeta1-->3)GalNAcalpha-->R.
T8 1273-1442 Sentence denotes Moreover, beta4Gal-TIV, together with beta-1,3-N-acetylglucosaminyltransferase, was capable of synthesizing poly-N-acetyllactosamine in core 2 branched oligosaccharides.
T9 1443-1557 Sentence denotes On the other hand, beta4Gal-TI was found to be most efficient for poly-N-acetyllactosamine synthesis in N-glycans.
T10 1558-1838 Sentence denotes In contrast to beta4Gal-TI, the efficiency of beta4Gal-TIV decreased dramatically as the acceptors contained more N-acetyllactosamine repeats, consistent with the fact that core 2 branched O-glycans contain fewer and shorter poly-N-acetyllactosamines than N-glycans in many cells.
T11 1839-1976 Sentence denotes These results, as a whole, indicate that beta4Gal-TIV is responsible for poly-N-acetyllactosamine synthesis in core 2 branched O-glycans.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 18-37 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T2 178-197 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T3 235-254 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T4 343-346 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lex
T5 353-373 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamines
T6 681-700 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T7 895-914 https://glytoucan.org/Structures/Glycans/G64581RP denotes N-acetylglucosamine
T8 1206-1215 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T9 1206-1215 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T10 1386-1405 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T11 1514-1533 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T12 1672-1691 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T13 1788-1808 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamines
T14 1917-1936 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1456-1460 http://purl.obolibrary.org/obo/MAT_0000091 denotes hand

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1456-1460 Body_part denotes hand http://purl.obolibrary.org/obo/MAT_0000091

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 41-47 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T2 415-421 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T3 474-480 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T4 755-761 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T5 1409-1415 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T6 1731-1737 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T7 1950-1956 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 13-17 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T3 173-177 Cell denotes Poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T5 348-352 Cell denotes Poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T7 676-680 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T9 1381-1385 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T11 1509-1513 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T13 1783-1787 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T15 1912-1916 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 280-288 Body_part denotes backbone http://purl.obolibrary.org/obo/UBERON_0001130
T2 588-592 Body_part denotes milk http://purl.obolibrary.org/obo/UBERON_0001913
T3 1456-1460 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1456-1460 Body_part denotes hand http://purl.obolibrary.org/obo/MAT_0000091

sentences

Id Subject Object Predicate Lexical cue
T1 0-67 Sentence denotes Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans.
T2 68-172 Sentence denotes The requirement of novel beta-1,4-galactosyltransferase IV and beta-1,3-n-acetylglucosaminyltransferase.
T3 173-347 Sentence denotes Poly-N-acetyllactosamine is a unique carbohydrate composed of N-acetyllactosamine repeats and provides the backbone structure for additional modifications such as sialyl Lex.
T4 348-522 Sentence denotes Poly-N-acetyllactosamines in mucin-type O-glycans can be formed in core 2 branched oligosaccharides, which are synthesized by core 2 beta-1,6-N-acetylglucosaminyltransferase.
T5 523-833 Sentence denotes Using a beta-1, 4-galactosyltransferase (beta4Gal-TI) present in milk and the recently cloned beta-1,3-N-acetylglucosaminyltransferase, the formation of poly-N-acetyllactosamine was found to be extremely inefficient starting from a core 2 branched oligosaccharide, GlcNAcbeta1-->6(Galbeta1-->3)GalNAcalpha-->R.
T6 834-1070 Sentence denotes Since the majority of synthesized oligosaccharides contained N-acetylglucosamine at the nonreducing ends, galactosylation was judged to be inefficient, prompting us to test novel members of the beta4Gal-T gene family for this synthesis.
T7 1071-1272 Sentence denotes Using various synthetic acceptors and recombinant beta4Gal-Ts, beta4Gal-TIV was found to be most efficient in the addition of a single galactose residue to GlcNAcbeta1-->6(Galbeta1-->3)GalNAcalpha-->R.
T8 1273-1442 Sentence denotes Moreover, beta4Gal-TIV, together with beta-1,3-N-acetylglucosaminyltransferase, was capable of synthesizing poly-N-acetyllactosamine in core 2 branched oligosaccharides.
T9 1443-1557 Sentence denotes On the other hand, beta4Gal-TI was found to be most efficient for poly-N-acetyllactosamine synthesis in N-glycans.
T10 1558-1838 Sentence denotes In contrast to beta4Gal-TI, the efficiency of beta4Gal-TIV decreased dramatically as the acceptors contained more N-acetyllactosamine repeats, consistent with the fact that core 2 branched O-glycans contain fewer and shorter poly-N-acetyllactosamines than N-glycans in many cells.
T11 1839-1976 Sentence denotes These results, as a whole, indicate that beta4Gal-TIV is responsible for poly-N-acetyllactosamine synthesis in core 2 branched O-glycans.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-67 Sentence denotes Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans.
T2 68-172 Sentence denotes The requirement of novel beta-1,4-galactosyltransferase IV and beta-1,3-n-acetylglucosaminyltransferase.
T3 173-522 Sentence denotes Poly-N-acetyllactosamine is a unique carbohydrate composed of N-acetyllactosamine repeats and provides the backbone structure for additional modifications such as sialyl Lex. Poly-N-acetyllactosamines in mucin-type O-glycans can be formed in core 2 branched oligosaccharides, which are synthesized by core 2 beta-1,6-N-acetylglucosaminyltransferase.
T4 523-1070 Sentence denotes Using a beta-1, 4-galactosyltransferase (beta4Gal-TI) present in milk and the recently cloned beta-1,3-N-acetylglucosaminyltransferase, the formation of poly-N-acetyllactosamine was found to be extremely inefficient starting from a core 2 branched oligosaccharide, GlcNAcbeta1-->6(Galbeta1-->3)GalNAcalpha-->R. Since the majority of synthesized oligosaccharides contained N-acetylglucosamine at the nonreducing ends, galactosylation was judged to be inefficient, prompting us to test novel members of the beta4Gal-T gene family for this synthesis.
T5 1071-1442 Sentence denotes Using various synthetic acceptors and recombinant beta4Gal-Ts, beta4Gal-TIV was found to be most efficient in the addition of a single galactose residue to GlcNAcbeta1-->6(Galbeta1-->3)GalNAcalpha-->R. Moreover, beta4Gal-TIV, together with beta-1,3-N-acetylglucosaminyltransferase, was capable of synthesizing poly-N-acetyllactosamine in core 2 branched oligosaccharides.
T6 1443-1557 Sentence denotes On the other hand, beta4Gal-TI was found to be most efficient for poly-N-acetyllactosamine synthesis in N-glycans.
T7 1558-1838 Sentence denotes In contrast to beta4Gal-TI, the efficiency of beta4Gal-TIV decreased dramatically as the acceptors contained more N-acetyllactosamine repeats, consistent with the fact that core 2 branched O-glycans contain fewer and shorter poly-N-acetyllactosamines than N-glycans in many cells.
T8 1839-1976 Sentence denotes These results, as a whole, indicate that beta4Gal-TIV is responsible for poly-N-acetyllactosamine synthesis in core 2 branched O-glycans.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 41-47 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T2 415-421 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T3 474-480 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T4 755-761 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T5 1409-1415 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T6 1731-1737 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T7 1950-1956 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 280-288 Body_part denotes backbone http://purl.obolibrary.org/obo/UBERON_0001130
T2 588-592 Body_part denotes milk http://purl.obolibrary.org/obo/UBERON_0001913
T3 1456-1460 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 13-17 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T3 173-177 Cell denotes Poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T5 348-352 Cell denotes Poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T7 676-680 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T9 1381-1385 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T11 1509-1513 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T13 1783-1787 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775
T15 1912-1916 Cell denotes poly http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775