PubMed:9850850 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	79-101	cell_type	denotes	Thymic dendritic cells
T2	103-105	cell_type	denotes	DC
T3	242-251	cell_type	denotes	thymic DC
T4	259-274	cell_type	denotes	T-lineage cells
T5	488-490	cell_type	denotes	DC
T6	502-509	cell_type	denotes	T cells
T7	562-564	cell_type	denotes	DC
T8	583-605	cell_type	denotes	lymphoid/DC precursors
T9	635-648	cell_type	denotes	myeloid cells
T10	666-675	cell_type	denotes	thymic DC
T11	711-734	cell_type	denotes	myeloid-related lineage
T12	751-769	cell_type	denotes	myeloid-related DC
T13	771-819	protein	denotes	granulocyte-macrophage colony-stimulating factor
T14	865-884	cell_type	denotes	lymphoid-related DC
T15	906-908	cell_type	denotes	DC
T16	944-958	cell_type	denotes	mature T cells
T17	1047-1053	protein	denotes	Ikaros
T18	1054-1075	protein	denotes	transcription factors
T19	1103-1127	cell_type	denotes	lymphoid precursor cells
T20	1132-1153	cell_type	denotes	mature lymphoid cells
T21	1161-1163	cell_type	denotes	DC

Id	Subject	Object	Predicate	Lexical cue
S1	0-78	Sentence	denotes	The linkage between T-cell and dendritic cell development in the mouse thymus.
S2	79-197	Sentence	denotes	Thymic dendritic cells (DC) mediate negative selection at a relatively late stage of the T-cell developmental pathway.
S3	198-351	Sentence	denotes	We present evidence that the development of thymic DC and of T-lineage cells is linked via a common precursor at an early stage of thymocyte development.
S4	352-576	Sentence	denotes	T-lineage precursor populations from the adult mouse thymus, prior to T-cell receptor gene rearrangement, display a capacity to produce DC as well as T cells in the thymus, and are very efficient precursors of DC in culture.
S5	577-735	Sentence	denotes	These lymphoid/DC precursors have little capacity to form myeloid cells, indicating that thymic DC are a lymphoid-related rather than myeloid-related lineage.
S6	736-905	Sentence	denotes	In contrast to myeloid-related DC, granulocyte-macrophage colony-stimulating factor is not required for the development of these lymphoid-related DC in vivo or in vitro.
S7	906-1003	Sentence	denotes	DC can develop in mutant mice lacking mature T cells, provided the common precursors are present.
S8	1004-1164	Sentence	denotes	However, in mutant mice lacking functional Ikaros transcription factors, there are deficiencies in lymphoid precursor cells, in mature lymphoid cells and in DC.

Id	Subject	Object	Predicate	Lexical cue
C1	20-57	NP	denotes	T-cell and dendritic cell development
C2	79-106	NP	denotes	Thymic dendritic cells (DC)
C3	209-217	NP	denotes	evidence
C4	218-222	NP	denotes	that
C7	242-251	NP	denotes	thymic DC
C6	242-274	NP	denotes	thymic DC and of T-lineage cells
C5	223-274	NP	denotes	the development of thymic DC and of T-lineage cells
C8	389-411	NP	denotes	the adult mouse thymus
C10	488-490	NP	denotes	DC
C9	488-509	NP	denotes	DC as well as T cells
C11	513-523	NP	denotes	the thymus
C12	562-564	NP	denotes	DC
C13	666-675	NP	denotes	thymic DC
C14	906-908	NP	denotes	DC
C15	1161-1163	NP	denotes	DC
R1	C4	C3	coref-relat	that,evidence
R2	C7	C2	coref-ident	thymic DC,Thymic dendritic cells (DC)
R3	C5	C1	coref-ident	the development of thymic DC and of T-lineage cells,T-cell and dendritic cell development
R4	C9	C6	coref-ident	DC as well as T cells,thymic DC and of T-lineage cells
R5	C11	C8	coref-ident	the thymus,the adult mouse thymus
R6	C12	C10	coref-ident	DC,DC
R7	C13	C7	coref-ident	thymic DC,thymic DC
R8	C14	C12	coref-ident	DC,DC
R9	C15	C14	coref-ident	DC,DC

Id	Subject	Object	Predicate	Lexical cue
T1	65-77	body_part	denotes	mouse thymus
T2	79-101	cell_type	denotes	Thymic dendritic cells
T3	103-105	cell_type	denotes	DC
T4	168-196	other_name	denotes	T-cell developmental pathway
T5	242-251	cell_type	denotes	thymic DC
T6	259-274	cell_type	denotes	T-lineage cells
T7	329-350	other_name	denotes	thymocyte development
T8	393-398	body_part	denotes	adult
T9	399-411	body_part	denotes	mouse thymus
T10	422-456	other_name	denotes	T-cell receptor gene rearrangement
T11	488-490	cell_type	denotes	DC
T12	502-509	cell_type	denotes	T cells
T13	517-523	body_part	denotes	thymus
T14	562-564	cell_type	denotes	DC
T15	583-592	cell_type	denotes	lymphoid/
T16	592-594	cell_type	denotes	DC
T17	635-648	cell_type	denotes	myeloid cells
T18	666-675	cell_type	denotes	thymic DC
T19	711-734	cell_type	denotes	myeloid-related lineage
T20	751-766	cell_type	denotes	myeloid-related
T21	767-769	cell_type	denotes	DC
T22	771-819	protein_family_or_group	denotes	granulocyte-macrophage colony-stimulating factor
T23	865-881	cell_type	denotes	lymphoid-related
T24	882-884	cell_type	denotes	DC
T25	906-908	cell_type	denotes	DC
T26	924-935	other_artificial_source	denotes	mutant mice
T27	944-950	cell_type	denotes	mature
T28	951-958	cell_type	denotes	T cells
T29	1016-1027	other_artificial_source	denotes	mutant mice
T30	1047-1053	protein_family_or_group	denotes	Ikaros
T31	1054-1075	protein_family_or_group	denotes	transcription factors
T32	1103-1127	cell_type	denotes	lymphoid precursor cells
T33	1132-1153	cell_type	denotes	mature lymphoid cells
T34	1161-1163	cell_type	denotes	DC