PubMed:9838061
Annnotations
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 87-92 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 334-339 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-14 | protein | denotes | Anaphylatoxins |
| T2 | 15-18 | protein | denotes | C5a |
| T3 | 23-26 | protein | denotes | C3a |
| T4 | 34-55 | protein | denotes | nuclear factor kappaB |
| T5 | 70-102 | cell_type | denotes | human peripheral blood monocytes |
| T6 | 108-122 | protein | denotes | anaphylatoxins |
| T7 | 123-126 | protein | denotes | C5a |
| T8 | 131-134 | protein | denotes | C3a |
| T9 | 222-225 | protein | denotes | C5a |
| T10 | 230-233 | protein | denotes | C3a |
| T11 | 290-293 | protein | denotes | C5a |
| T12 | 298-301 | protein | denotes | C3a |
| T13 | 317-349 | cell_type | denotes | human peripheral blood monocytes |
| T14 | 431-446 | DNA | denotes | kappaB sequence |
| T15 | 452-472 | protein | denotes | p50 and p65 proteins |
| T16 | 505-526 | protein | denotes | nuclear factor kappaB |
| T17 | 590-613 | protein | denotes | anti-peptide antibodies |
| T18 | 640-643 | protein | denotes | C5a |
| T19 | 652-658 | protein | denotes | kappaB |
| T20 | 787-802 | DNA | denotes | kappaB sequence |
| T21 | 885-897 | protein | denotes | IkappaBalpha |
| T22 | 947-973 | protein | denotes | anti-IkappaBalpha antibody |
| T23 | 1020-1026 | protein | denotes | kappaB |
| T24 | 1062-1065 | protein | denotes | C5a |
| T25 | 1070-1073 | protein | denotes | C3a |
| T26 | 1083-1096 | protein | denotes | cholera toxin |
| T27 | 1164-1170 | protein | denotes | kappaB |
| T28 | 1199-1207 | protein | denotes | TNFalpha |
| T29 | 1271-1285 | protein | denotes | anaphylatoxins |
| T30 | 1286-1289 | protein | denotes | C5a |
| T31 | 1294-1297 | protein | denotes | C3a |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-103 | Sentence | denotes | Anaphylatoxins C5a and C3a induce nuclear factor kappaB activation in human peripheral blood monocytes. |
| S2 | 104-189 | Sentence | denotes | The anaphylatoxins C5a and C3a are involved in the regulation of cytokine production. |
| S3 | 190-289 | Sentence | denotes | In this study the capability of C5a and C3a to induce transcription factor activation was examined. |
| S4 | 290-447 | Sentence | denotes | C5a and C3a stimulation of human peripheral blood monocytes resulted in nuclear expression of a DNA binding activity with specificity to the kappaB sequence. |
| S5 | 448-639 | Sentence | denotes | The p50 and p65 proteins, constituents of the prototypic nuclear factor kappaB, were identified as components of the DNA-protein complexes by anti-peptide antibodies in gel supershift assays. |
| S6 | 640-775 | Sentence | denotes | C5a induced kappaB binding activity was detected 15 min after agonist stimulation, peaked at 30-40 min, and remained detectable at 2 h. |
| S7 | 776-974 | Sentence | denotes | Binding to kappaB sequence was accompanied by an initial decrease and subsequent increase in the cytoplasmic IkappaBalpha levels, as detected by Western blotting using an anti-IkappaBalpha antibody. |
| S8 | 975-1128 | Sentence | denotes | Pertussis toxin treatment markedly decreased kappaB binding activities induced by both C5a and C3a, whereas cholera toxin displayed no inhibitory effect. |
| S9 | 1129-1226 | Sentence | denotes | Neither of the two toxins affected kappaB binding activity induced by TNFalpha in the same cells. |
| S10 | 1227-1397 | Sentence | denotes | These results imply a potential role of the anaphylatoxins C5a and C3a in regulating leukocytes gene expression through G protein-coupled transcription factor activation. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-26 | NP | denotes | Anaphylatoxins C5a and C3a |
| C2 | 70-102 | NP | denotes | human peripheral blood monocytes |
| C3 | 104-134 | NP | denotes | The anaphylatoxins C5a and C3a |
| C5 | 222-225 | NP | denotes | C5a |
| C4 | 222-233 | NP | denotes | C5a and C3a |
| C6 | 317-349 | NP | denotes | human peripheral blood monocytes |
| C7 | 427-446 | NP | denotes | the kappaB sequence |
| C8 | 448-472 | NP | denotes | The p50 and p65 proteins |
| C9 | 474-526 | NP | denotes | constituents of the prototypic nuclear factor kappaB |
| C10 | 640-643 | NP | denotes | C5a |
| C11 | 787-802 | NP | denotes | kappaB sequence |
| C12 | 1057-1073 | NP | denotes | both C5a and C3a |
| C13 | 1140-1154 | NP | denotes | the two toxins |
| C14 | 1267-1297 | NP | denotes | the anaphylatoxins C5a and C3a |
| R1 | C3 | C1 | coref-ident | The anaphylatoxins C5a and C3a,Anaphylatoxins C5a and C3a |
| R2 | C4 | C3 | coref-ident | C5a and C3a,The anaphylatoxins C5a and C3a |
| R3 | C6 | C2 | coref-ident | human peripheral blood monocytes,human peripheral blood monocytes |
| R4 | C9 | C8 | coref-appos | constituents of the prototypic nuclear factor kappaB,The p50 and p65 proteins |
| R5 | C10 | C5 | coref-ident | C5a,C5a |
| R6 | C11 | C7 | coref-ident | kappaB sequence,the kappaB sequence |
| R7 | C12 | C4 | coref-ident | both C5a and C3a,C5a and C3a |
| R8 | C13 | C12 | coref-ident | the two toxins,both C5a and C3a |
| R9 | C14 | C13 | coref-ident | the anaphylatoxins C5a and C3a,the two toxins |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-14 | protein_family_or_group | denotes | Anaphylatoxins |
| T2 | 15-18 | protein_molecule | denotes | C5a |
| T3 | 23-26 | protein_molecule | denotes | C3a |
| T4 | 34-55 | protein_complex | denotes | nuclear factor kappaB |
| T5 | 70-102 | cell_type | denotes | human peripheral blood monocytes |
| T6 | 108-122 | protein_family_or_group | denotes | anaphylatoxins |
| T7 | 123-126 | protein_molecule | denotes | C5a |
| T8 | 131-134 | protein_molecule | denotes | C3a |
| T9 | 222-225 | protein_molecule | denotes | C5a |
| T10 | 230-233 | protein_molecule | denotes | C3a |
| T11 | 244-275 | other_name | denotes | transcription factor activation |
| T12 | 290-293 | protein_molecule | denotes | C5a |
| T13 | 298-301 | protein_molecule | denotes | C3a |
| T14 | 317-349 | cell_type | denotes | human peripheral blood monocytes |
| T15 | 386-406 | other_name | denotes | DNA binding activity |
| T16 | 431-446 | DNA_domain_or_region | denotes | kappaB sequence |
| T17 | 505-526 | protein_complex | denotes | nuclear factor kappaB |
| T18 | 590-613 | protein_family_or_group | denotes | anti-peptide antibodies |
| T19 | 617-638 | other_name | denotes | gel supershift assays |
| T20 | 640-643 | protein_molecule | denotes | C5a |
| T21 | 652-658 | protein_molecule | denotes | kappaB |
| T22 | 787-802 | DNA_domain_or_region | denotes | kappaB sequence |
| T23 | 873-884 | other_name | denotes | cytoplasmic |
| T24 | 885-897 | protein_molecule | denotes | IkappaBalpha |
| T25 | 921-937 | other_name | denotes | Western blotting |
| T26 | 947-952 | protein_family_or_group | denotes | anti- |
| T27 | 952-964 | protein_molecule | denotes | IkappaBalpha |
| T28 | 1020-1026 | protein_molecule | denotes | kappaB |
| T29 | 1062-1065 | protein_molecule | denotes | C5a |
| T30 | 1070-1073 | protein_molecule | denotes | C3a |
| T31 | 1083-1096 | protein_molecule | denotes | cholera toxin |
| T32 | 1164-1170 | protein_molecule | denotes | kappaB |
| T33 | 1199-1207 | protein_molecule | denotes | TNFalpha |
| T34 | 1271-1285 | protein_family_or_group | denotes | anaphylatoxins |
| T35 | 1286-1289 | protein_molecule | denotes | C5a |
| T36 | 1294-1297 | protein_molecule | denotes | C3a |
| T37 | 1312-1338 | other_name | denotes | leukocytes gene expression |
| T38 | 1347-1364 | other_name | denotes | G protein-coupled |
| T39 | 1365-1396 | other_name | denotes | transcription factor activation |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 975-984 | Disease | denotes | Pertussis | http://purl.obolibrary.org/obo/MONDO_0005077 |
| T2 | 1083-1090 | Disease | denotes | cholera | http://purl.obolibrary.org/obo/MONDO_0015766 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 70-75 | OrganismTaxon | denotes | human | 9606 |
| T2 | 317-322 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 87-92 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 93-102 | Body_part | denotes | monocytes | http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054 |
| T4 | 334-339 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T5 | 340-349 | Body_part | denotes | monocytes | http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054 |
| T7 | 873-884 | Body_part | denotes | cytoplasmic | http://purl.obolibrary.org/obo/GO_0005737 |
| T8 | 1312-1322 | Body_part | denotes | leukocytes | http://purl.obolibrary.org/obo/CL_0000738 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 93-102 | Cell | denotes | monocytes | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |
| T3 | 340-349 | Cell | denotes | monocytes | http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054 |
| T5 | 1312-1322 | Cell | denotes | leukocytes | http://purl.obolibrary.org/obo/CL:0000738 |