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PubMed:9824619 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-75 Sentence denotes Role of the transcription factor AP-1 in melanoma differentiation (review).
TextSentencer_T2 76-292 Sentence denotes Although the molecular details remain to be elucidated, temporal changes in gene expression that result in discrete biochemical alterations and growth arrest are primary determinants of terminal cell differentiation.
TextSentencer_T3 293-413 Sentence denotes The control of gene expression is inextricably associated with proteins that can initiate or inhibit gene transcription.
TextSentencer_T4 414-612 Sentence denotes Specific genes contain within their promoter regions, DNA sequences that permit the binding of transactivating and transinhibiting proteins that can initiate or suppress transcription, respectively.
TextSentencer_T5 613-879 Sentence denotes Activating protein-1 (AP-1), a dimeric complex consisting of proteins encoded by the Jun and Fos gene families, is a transcription factor induced by a variety of signals, including those eliciting proliferation, differentiation and programmed cell death (apoptosis).
TextSentencer_T6 880-1006 Sentence denotes We presently review the potential role of AP-1 proteins in differentiation with specific emphasis on melanoma differentiation.
T1 0-75 Sentence denotes Role of the transcription factor AP-1 in melanoma differentiation (review).
T2 76-292 Sentence denotes Although the molecular details remain to be elucidated, temporal changes in gene expression that result in discrete biochemical alterations and growth arrest are primary determinants of terminal cell differentiation.
T3 293-413 Sentence denotes The control of gene expression is inextricably associated with proteins that can initiate or inhibit gene transcription.
T4 414-612 Sentence denotes Specific genes contain within their promoter regions, DNA sequences that permit the binding of transactivating and transinhibiting proteins that can initiate or suppress transcription, respectively.
T5 613-879 Sentence denotes Activating protein-1 (AP-1), a dimeric complex consisting of proteins encoded by the Jun and Fos gene families, is a transcription factor induced by a variety of signals, including those eliciting proliferation, differentiation and programmed cell death (apoptosis).
T6 880-1006 Sentence denotes We presently review the potential role of AP-1 proteins in differentiation with specific emphasis on melanoma differentiation.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 12-37 gene:3725 denotes transcription factor AP-1
T1 41-49 disease:C0025202 denotes melanoma
T2 922-926 gene:3727 denotes AP-1
T3 981-989 disease:C0025202 denotes melanoma
T4 922-926 gene:3726 denotes AP-1
T5 981-989 disease:C0025202 denotes melanoma
T6 922-926 gene:2353 denotes AP-1
T7 981-989 disease:C0025202 denotes melanoma
T8 922-926 gene:2354 denotes AP-1
T9 981-989 disease:C0025202 denotes melanoma
T10 922-926 gene:3725 denotes AP-1
T11 981-989 disease:C0025202 denotes melanoma
R1 T0 T1 associated_with transcription factor AP-1,melanoma
R2 T2 T3 associated_with AP-1,melanoma
R3 T4 T5 associated_with AP-1,melanoma
R4 T6 T7 associated_with AP-1,melanoma
R5 T8 T9 associated_with AP-1,melanoma
R6 T10 T11 associated_with AP-1,melanoma

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
9824619-0#12#37#gene3725 12-37 gene3725 denotes transcription factor AP-1
9824619-0#41#49#diseaseC0025202 41-49 diseaseC0025202 denotes melanoma
12#37#gene372541#49#diseaseC0025202 9824619-0#12#37#gene3725 9824619-0#41#49#diseaseC0025202 associated_with transcription factor AP-1,melanoma

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2804 922-926 gene:2353 denotes AP-1
T2805 981-989 disease:C0025202 denotes melanoma
R1 T2804 T2805 associated_with AP-1,melanoma
R2 T2804 T2805 associated_with AP-1,melanoma
R3 T2804 T2805 associated_with AP-1,melanoma
R4 T2804 T2805 associated_with AP-1,melanoma