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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-80 Sentence denotes Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma.
T2 81-192 Sentence denotes GLUCOCORTICOIDS are potent inhibitors of inflammatory processes and are widely used in the treatment of asthma.
T3 193-517 Sentence denotes The anti-inflammatory effects are mediated either by direct binding of the glucocorticoid/glucocorticoid receptor complex to glucocorticoid responsive elements in the promoter region of genes, or by an interaction of this complex with other transcription factors, in particular activating protein-1 or nuclear factor-kappaB.
T4 518-665 Sentence denotes Glucocorticoids inhibit many inflammation-associated molecules such as cytokines, chemokines, arachidonic acid metabolites, and adhesion molecules.
T5 666-749 Sentence denotes In contrast, anti-inflammatory mediators often are up-regulated by glucocorticoids.
T6 750-927 Sentence denotes In vivo studies have shown that treatment of asthmatic patients with inhaled glucocorticoids inhibits the bronchial inflammation and simultaneously improves their lung function.
T7 928-1073 Sentence denotes In this review, our current knowledge of the mechanism of action of glucocorticoids and their anti-inflammatory potential in asthma is described.
T8 1074-1263 Sentence denotes Since bronchial epithelial cells may be important targets for glucocorticoid therapy in asthma, the effects of glucocorticoids on epithelial expressed inflammatory genes will be emphasized.
T1 0-80 Sentence denotes Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma.
T2 81-192 Sentence denotes GLUCOCORTICOIDS are potent inhibitors of inflammatory processes and are widely used in the treatment of asthma.
T3 193-517 Sentence denotes The anti-inflammatory effects are mediated either by direct binding of the glucocorticoid/glucocorticoid receptor complex to glucocorticoid responsive elements in the promoter region of genes, or by an interaction of this complex with other transcription factors, in particular activating protein-1 or nuclear factor-kappaB.
T4 518-665 Sentence denotes Glucocorticoids inhibit many inflammation-associated molecules such as cytokines, chemokines, arachidonic acid metabolites, and adhesion molecules.
T5 666-749 Sentence denotes In contrast, anti-inflammatory mediators often are up-regulated by glucocorticoids.
T6 750-927 Sentence denotes In vivo studies have shown that treatment of asthmatic patients with inhaled glucocorticoids inhibits the bronchial inflammation and simultaneously improves their lung function.
T7 928-1073 Sentence denotes In this review, our current knowledge of the mechanism of action of glucocorticoids and their anti-inflammatory potential in asthma is described.
T8 1074-1263 Sentence denotes Since bronchial epithelial cells may be important targets for glucocorticoid therapy in asthma, the effects of glucocorticoids on epithelial expressed inflammatory genes will be emphasized.

NEUROSES

Id Subject Object Predicate Lexical cue
T1 0-15 CHEBI_24261 denotes Glucocorticoids
T2 81-96 CHEBI_24261 denotes GLUCOCORTICOIDS
T3 268-282 CHEBI_24261 denotes glucocorticoid
T4 283-297 CHEBI_24261 denotes glucocorticoid
T5 318-332 CHEBI_24261 denotes glucocorticoid
T6 518-533 CHEBI_24261 denotes Glucocorticoids
T7 733-748 CHEBI_24261 denotes glucocorticoids
T8 827-842 CHEBI_24261 denotes glucocorticoids
T9 996-1011 CHEBI_24261 denotes glucocorticoids
T10 1136-1150 CHEBI_24261 denotes glucocorticoid
T11 1185-1200 CHEBI_24261 denotes glucocorticoids
T13 122-134 PATO_0002104 denotes inflammatory
T14 202-214 PATO_0002104 denotes inflammatory
T15 684-696 PATO_0002104 denotes inflammatory
T16 1027-1039 PATO_0002104 denotes inflammatory
T17 1225-1237 PATO_0002104 denotes inflammatory
T19 307-314 PATO_0001504 denotes complex
T20 415-422 PATO_0001504 denotes complex
T21 333-343 PATO_0000487 denotes responsive
T22 344-352 CHEBI_33250 denotes elements
T23 482-489 CHEBI_16541 denotes protein
T24 482-489 CHEBI_36080 denotes protein
T25 560-570 PATO_0001668 denotes associated
T26 571-580 CHEBI_25367 denotes molecules
T27 655-664 CHEBI_25367 denotes molecules
T29 629-640 CHEBI_25212 denotes metabolites
T30 918-926 PATO_0000173 denotes function