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PubMed:9763616 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 4-52 DNA denotes interleukin 2 receptor alpha chain/CD25 promoter
T2 69-104 protein denotes nuclear factor of activated T cells
T3 128-179 protein denotes murine interleukin (IL)-2 receptor alpha chain/CD25
T4 272-322 protein denotes nuclear factor of activated T cell (NF-AT) factors
T5 354-367 DNA denotes CD25 promoter
T6 381-388 cell_type denotes T cells
T7 390-396 protein denotes NF-ATp
T8 401-407 protein denotes NF-ATc
T9 433-456 DNA denotes positions -585 and -650
T10 481-503 DNA denotes proximal CD25 promoter
T11 531-543 DNA denotes NF-AT motifs
T12 545-563 DNA denotes nonconsensus sites
T13 595-612 protein denotes AP-1-like factors
T14 647-652 protein denotes NF-AT
T15 693-699 protein denotes NF-ATp
T16 732-745 DNA denotes CD25 promoter
T17 749-756 cell_type denotes T cells
T18 761-774 cell_type denotes T lymphocytes
T19 780-786 protein denotes NF-ATp
T20 821-825 protein denotes CD25
T21 869-882 protein denotes IL-2 receptor
T22 917-920 protein denotes TCR
T23 922-925 protein denotes CD3
T24 979-984 protein denotes NF-AT
T25 1015-1043 protein denotes high affinity IL-2 receptors
T26 1073-1076 protein denotes TCR
T27 1099-1103 protein denotes IL-2
T28 1108-1143 DNA denotes IL-2 receptor alpha chain promoters
T29 1176-1189 protein denotes NF-AT factors

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-105 Sentence denotes The interleukin 2 receptor alpha chain/CD25 promoter is a target for nuclear factor of activated T cells.
S2 106-253 Sentence denotes The expression of the murine interleukin (IL)-2 receptor alpha chain/CD25 is strongly induced at the transcriptional level after T cell activation.
S3 254-389 Sentence denotes We show here that nuclear factor of activated T cell (NF-AT) factors are involved in the control of CD25 promoter induction in T cells.
S4 390-504 Sentence denotes NF-ATp and NF-ATc bind to two sites around positions -585 and -650 located upstream of the proximal CD25 promoter.
S5 505-613 Sentence denotes Immediately 3' from these NF-AT motifs, nonconsensus sites are located for the binding of AP-1-like factors.
S6 614-757 Sentence denotes Mutations of sites that suppress NF-AT binding impair the induction and strong NF-ATp-mediated transactivation of the CD25 promoter in T cells.
S7 758-938 Sentence denotes In T lymphocytes from NF-ATp-deficient mice, the expression of CD25 is severely impaired, leading to a delayed IL-2 receptor expression after T cell receptor (TCR)/CD3 stimulation.
S8 939-1190 Sentence denotes Our data indicate an important role for NF-AT in the faithful expression of high affinity IL-2 receptors and a close link between the TCR-mediated induction of IL-2 and IL-2 receptor alpha chain promoters, both of which are regulated by NF-AT factors.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 69-104 NP denotes nuclear factor of activated T cells
C2 272-322 NP denotes nuclear factor of activated T cell (NF-AT) factors
C3 381-388 NP denotes T cells
C4 614-632 NP denotes Mutations of sites
C5 633-637 NP denotes that
C6 749-756 NP denotes T cells
C7 979-984 NP denotes NF-AT
C8 1099-1143 NP denotes IL-2 and IL-2 receptor alpha chain promoters
C9 1145-1158 NP denotes both of which
C10 1176-1189 NP denotes NF-AT factors
R1 C2 C1 coref-ident nuclear factor of activated T cell (NF-AT) factors,nuclear factor of activated T cells
R2 C5 C4 coref-relat that,Mutations of sites
R3 C6 C3 coref-ident T cells,T cells
R4 C7 C2 coref-ident NF-AT,nuclear factor of activated T cell (NF-AT) factors
R5 C9 C8 coref-pron both of which,IL-2 and IL-2 receptor alpha chain promoters
R6 C10 C7 coref-ident NF-AT factors,NF-AT

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 4-38 protein_subunit denotes interleukin 2 receptor alpha chain
T2 38-43 protein_molecule denotes /CD25
T3 69-104 protein_family_or_group denotes nuclear factor of activated T cells
T4 128-174 protein_subunit denotes murine interleukin (IL)-2 receptor alpha chain
T5 235-252 other_name denotes T cell activation
T6 272-322 protein_family_or_group denotes nuclear factor of activated T cell (NF-AT) factors
T7 354-358 protein_molecule denotes CD25
T8 381-388 cell_type denotes T cells
T9 390-396 protein_molecule denotes NF-ATp
T10 401-407 protein_molecule denotes NF-ATc
T11 481-489 DNA_domain_or_region denotes proximal
T12 490-494 protein_molecule denotes CD25
T13 531-543 DNA_family_or_group denotes NF-AT motifs
T14 545-563 DNA_family_or_group denotes nonconsensus sites
T15 595-599 protein_molecule denotes AP-1
T16 647-652 protein_molecule denotes NF-AT
T17 693-699 protein_molecule denotes NF-ATp
T18 732-736 protein_molecule denotes CD25
T19 749-756 cell_type denotes T cells
T20 761-774 cell_type denotes T lymphocytes
T21 780-786 protein_molecule denotes NF-ATp
T22 821-825 protein_molecule denotes CD25
T23 869-882 protein_molecule denotes IL-2 receptor
T24 900-917 other_name denotes T cell receptor (
T25 917-920 protein_molecule denotes TCR
T26 922-925 protein_molecule denotes CD3
T27 979-984 protein_family_or_group denotes NF-AT
T28 1015-1028 protein_molecule denotes high affinity
T29 1029-1033 protein_molecule denotes IL-2
T30 1073-1076 protein_molecule denotes TCR
T31 1099-1103 DNA_domain_or_region denotes IL-2
T32 1108-1112 protein_molecule denotes IL-2
T33 1176-1181 protein_family_or_group denotes NF-AT