> top > docs > PubMed:9763613 > annotations

PubMed:9763613 JSONTXT

Annnotations TAB JSON ListView MergeView

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-146 Sentence denotes A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.
T2 147-508 Sentence denotes Despite overwhelming evidence that enhanced production of the p75 tumor necrosis factor receptor (p75TNF-R) accompanies development of specific human inflammatory pathologies such as multi-organ failure during sepsis, inflammatory liver disease, pancreatitis, respiratory distress syndrome, or AIDS, the function of this receptor remains poorly defined in vivo.
T3 509-832 Sentence denotes We show here that at levels relevant to human disease, production of the human p75TNF-R in transgenic mice results in a severe inflammatory syndrome involving mainly the pancreas, liver, kidney, and lung, and characterized by constitutively increased NF-kappaB activity in the peripheral blood mononuclear cell compartment.
T4 833-1008 Sentence denotes This process is shown to evolve independently of the presence of TNF, lymphotoxin alpha, or the p55TNF-R, although coexpression of a human TNF transgene accelerated pathology.
T5 1009-1234 Sentence denotes These results establish an independent role for enhanced p75TNF-R production in the pathogenesis of inflammatory disease and implicate the direct involvement of this receptor in a wide range of human inflammatory pathologies.
T1 0-146 Sentence denotes A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.
T2 147-508 Sentence denotes Despite overwhelming evidence that enhanced production of the p75 tumor necrosis factor receptor (p75TNF-R) accompanies development of specific human inflammatory pathologies such as multi-organ failure during sepsis, inflammatory liver disease, pancreatitis, respiratory distress syndrome, or AIDS, the function of this receptor remains poorly defined in vivo.
T3 509-832 Sentence denotes We show here that at levels relevant to human disease, production of the human p75TNF-R in transgenic mice results in a severe inflammatory syndrome involving mainly the pancreas, liver, kidney, and lung, and characterized by constitutively increased NF-kappaB activity in the peripheral blood mononuclear cell compartment.
T4 833-1008 Sentence denotes This process is shown to evolve independently of the presence of TNF, lymphotoxin alpha, or the p55TNF-R, although coexpression of a human TNF transgene accelerated pathology.
T5 1009-1234 Sentence denotes These results establish an independent role for enhanced p75TNF-R production in the pathogenesis of inflammatory disease and implicate the direct involvement of this receptor in a wide range of human inflammatory pathologies.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 23-57 protein denotes p75 tumor necrosis factor receptor
T2 59-67 protein denotes p75TNF-R
T3 106-109 protein denotes TNF
T4 111-128 protein denotes lymphotoxin alpha
T5 137-146 protein denotes p55TNF-R.
T6 209-243 protein denotes p75 tumor necrosis factor receptor
T7 245-253 protein denotes p75TNF-R
T8 582-596 protein denotes human p75TNF-R
T9 760-769 protein denotes NF-kappaB
T10 786-819 cell_type denotes peripheral blood mononuclear cell
T11 898-901 protein denotes TNF
T12 903-920 protein denotes lymphotoxin alpha
T13 929-937 protein denotes p55TNF-R
T14 966-985 DNA denotes human TNF transgene
T15 1066-1074 protein denotes p75TNF-R

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-146 Sentence denotes A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.
S2 147-508 Sentence denotes Despite overwhelming evidence that enhanced production of the p75 tumor necrosis factor receptor (p75TNF-R) accompanies development of specific human inflammatory pathologies such as multi-organ failure during sepsis, inflammatory liver disease, pancreatitis, respiratory distress syndrome, or AIDS, the function of this receptor remains poorly defined in vivo.
S3 509-832 Sentence denotes We show here that at levels relevant to human disease, production of the human p75TNF-R in transgenic mice results in a severe inflammatory syndrome involving mainly the pancreas, liver, kidney, and lung, and characterized by constitutively increased NF-kappaB activity in the peripheral blood mononuclear cell compartment.
S4 833-1008 Sentence denotes This process is shown to evolve independently of the presence of TNF, lymphotoxin alpha, or the p55TNF-R, although coexpression of a human TNF transgene accelerated pathology.
S5 1009-1234 Sentence denotes These results establish an independent role for enhanced p75TNF-R production in the pathogenesis of inflammatory disease and implicate the direct involvement of this receptor in a wide range of human inflammatory pathologies.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 19-68 NP denotes the p75 tumor necrosis factor receptor (p75TNF-R)
C2 106-145 NP denotes TNF, lymphotoxin alpha, or the p55TNF-R
C3 155-176 NP denotes overwhelming evidence
C4 177-181 NP denotes that
C6 205-254 NP denotes the p75 tumor necrosis factor receptor (p75TNF-R)
C5 182-254 NP denotes enhanced production of the p75 tumor necrosis factor receptor (p75TNF-R)
C7 282-445 NP denotes specific human inflammatory pathologies such as multi-organ failure during sepsis, inflammatory liver disease, pancreatitis, respiratory distress syndrome, or AIDS
C8 463-476 NP denotes this receptor
C9 898-937 NP denotes TNF, lymphotoxin alpha, or the p55TNF-R
C10 1057-1085 NP denotes enhanced p75TNF-R production
C11 1170-1183 NP denotes this receptor
C12 1187-1233 NP denotes a wide range of human inflammatory pathologies
R1 C4 C3 coref-relat that,overwhelming evidence
R2 C6 C1 coref-ident the p75 tumor necrosis factor receptor (p75TNF-R),the p75 tumor necrosis factor receptor (p75TNF-R)
R3 C8 C6 coref-ident this receptor,the p75 tumor necrosis factor receptor (p75TNF-R)
R4 C9 C2 coref-ident "TNF, lymphotoxin alpha, or the p55TNF-R","TNF, lymphotoxin alpha, or the p55TNF-R"
R5 C10 C5 coref-ident enhanced p75TNF-R production,enhanced production of the p75 tumor necrosis factor receptor (p75TNF-R)
R6 C11 C8 coref-ident this receptor,this receptor
R7 C12 C7 coref-ident a wide range of human inflammatory pathologies,"specific human inflammatory pathologies such as multi-organ failure during sepsis, inflammatory liver disease, pancreatitis, respiratory distress syndrome, or AIDS"

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 23-57 protein_molecule denotes p75 tumor necrosis factor receptor
T2 59-67 protein_molecule denotes p75TNF-R
T3 72-90 other_name denotes organ inflammation
T4 106-109 protein_family_or_group denotes TNF
T5 111-128 protein_molecule denotes lymphotoxin alpha
T6 137-146 protein_molecule denotes p55TNF-R.
T7 209-243 protein_molecule denotes p75 tumor necrosis factor receptor
T8 245-253 protein_molecule denotes p75TNF-R
T9 291-321 other_name denotes human inflammatory pathologies
T10 357-363 other_name denotes sepsis
T11 365-377 other_name denotes inflammatory
T12 378-383 body_part denotes liver
T13 393-405 other_name denotes pancreatitis
T14 407-436 other_name denotes respiratory distress syndrome
T15 441-445 other_name denotes AIDS
T16 549-562 other_name denotes human disease
T17 582-587 protein_molecule denotes human
T18 588-596 protein_molecule denotes p75TNF-R
T19 636-657 other_name denotes inflammatory syndrome
T20 679-687 body_part denotes pancreas
T21 689-694 body_part denotes liver
T22 696-702 body_part denotes kidney
T23 708-712 body_part denotes lung
T24 760-769 protein_complex denotes NF-kappaB
T25 786-819 cell_type denotes peripheral blood mononuclear cell
T26 898-901 protein_family_or_group denotes TNF
T27 903-920 protein_molecule denotes lymphotoxin alpha
T28 929-937 protein_molecule denotes p55TNF-R
T29 966-985 DNA_domain_or_region denotes human TNF transgene
T30 1066-1074 protein_molecule denotes p75TNF-R
T31 1109-1129 other_name denotes inflammatory disease
T32 1203-1233 other_name denotes human inflammatory pathologies