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PubMed:9746760 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 1678-1682 gene:2532 denotes DARC
T1 1705-1712 disease:C0024530 denotes malaria
R1 T0 T1 associated_with DARC,malaria

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 47-58 DNA denotes FY*B allele
T2 66-95 DNA denotes Duffy chemokine receptor gene
T3 222-232 protein denotes Antibodies
T4 236-250 protein denotes Duffy antigens
T5 348-361 protein denotes Duffy protein
T6 384-428 protein denotes Plasmodium vivax erythrocyte-binding protein
T7 464-474 protein denotes chemokines
T8 489-526 protein denotes Duffy Antigen Receptor for Chemokines
T9 528-532 protein denotes DARC
T10 544-570 protein denotes Duffy polymorphic antigens
T11 572-575 protein denotes Fya
T12 580-583 protein denotes Fyb
T13 598-619 DNA denotes FY*A and FY*B alleles
T14 637-658 protein denotes erythrocyte membranes
T15 885-898 DNA denotes FY*B promoter
T16 906-914 DNA denotes GATA box
T17 948-973 protein denotes erythrocyte Duffy protein
T18 1025-1045 DNA denotes FY*B coding sequence
T19 1216-1235 DNA denotes wild-type FY*B GATA
T20 1347-1417 DNA denotes restriction enzyme-generated restriction fragment length polymorphisms
T21 1567-1571 protein denotes DARC
T22 1678-1682 protein denotes DARC

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
9746760-11#67#71#gene2532 1678-1682 gene2532 denotes DARC
9746760-11#94#101#diseaseC0024530 1705-1712 diseaseC0024530 denotes malaria
67#71#gene253294#101#diseaseC0024530 9746760-11#67#71#gene2532 9746760-11#94#101#diseaseC0024530 associated_with DARC,malaria

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-148 Sentence denotes A novel mutation in the coding sequence of the FY*B allele of the Duffy chemokine receptor gene is associated with an altered erythrocyte phenotype.
S2 149-221 Sentence denotes The Duffy blood group system is of clinical and biological significance.
S3 222-343 Sentence denotes Antibodies to Duffy antigens are responsible for some cases of transfusion incompatibility and newborn hemolytic disease.
S4 344-535 Sentence denotes The Duffy protein is a receptor for the Plasmodium vivax erythrocyte-binding protein and is also a receptor for various chemokines (thus renamed Duffy Antigen Receptor for Chemokines [DARC]).
S5 536-659 Sentence denotes The two Duffy polymorphic antigens, Fya and Fyb (coded by the FY*A and FY*B alleles), are present on erythrocyte membranes.
S6 660-818 Sentence denotes The Fy(a-b-) phenotype is the predominant one in populations of black people and also occurs in other populations, including some non-Ashkenazi Jewish groups.
S7 819-974 Sentence denotes The Fy(a-b-) phenotype has been associated with a mutation in the FY*B promoter at the GATA box that abolishes the expression of erythrocyte Duffy protein.
S8 975-1159 Sentence denotes We describe here a novel mutation, present in the FY*B coding sequence (271C --> T), that is associated with some Fy(b-) phenotypes among non-Ashkenazi Jews and among Brazilian blacks.
S9 1160-1295 Sentence denotes The mutation is present in Fy(b-) individuals, who have wild-type FY*B GATA and carry the previously described 304G --> A substitution.
S10 1296-1418 Sentence denotes The 271C --> T and 304G --> A can be identified by restriction enzyme-generated restriction fragment length polymorphisms.
S11 1419-1610 Sentence denotes The 271C --> T substitution represents a considerable change in chemical nature (Arg91 --> Cys), one which may affect the antigenic determinants of DARC, and thus be of clinical significance.
S12 1611-1760 Sentence denotes The mutation may have implications for some physiological roles of DARC and be of interest in malaria research and in studies of population genetics.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 344-361 NP denotes The Duffy protein
C2 536-570 NP denotes The two Duffy polymorphic antigens
C3 572-620 NP denotes Fya and Fyb (coded by the FY*A and FY*B alleles)
C4 867-914 NP denotes a mutation in the FY*B promoter at the GATA box
C5 915-919 NP denotes that
C6 992-1008 NP denotes a novel mutation
C7 1060-1064 NP denotes that
C8 1187-1205 NP denotes Fy(b-) individuals
C9 1207-1210 NP denotes who
C10 1458-1514 NP denotes a considerable change in chemical nature (Arg91 --> Cys)
C11 1516-1519 NP denotes one
C12 1520-1525 NP denotes which
C13 1567-1571 NP denotes DARC
C14 1678-1682 NP denotes DARC
R1 C3 C2 coref-appos Fya and Fyb (coded by the FY*A and FY*B alleles),The two Duffy polymorphic antigens
R2 C5 C4 coref-relat that,a mutation in the FY*B promoter at the GATA box
R3 C7 C6 coref-relat that,a novel mutation
R4 C9 C8 coref-relat who,Fy(b-) individuals
R5 C11 C10 coref-pron one,a considerable change in chemical nature (Arg91 --> Cys)
R6 C12 C10 coref-relat which,a considerable change in chemical nature (Arg91 --> Cys)
R7 C13 C1 coref-ident DARC,The Duffy protein
R8 C14 C13 coref-ident DARC,DARC

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 47-58 DNA_domain_or_region denotes FY*B allele
T2 66-95 DNA_domain_or_region denotes Duffy chemokine receptor gene
T3 126-147 other_name denotes erythrocyte phenotype
T4 153-177 other_name denotes Duffy blood group system
T5 197-220 other_name denotes biological significance
T6 222-232 protein_family_or_group denotes Antibodies
T7 236-250 protein_family_or_group denotes Duffy antigens
T8 285-312 other_name denotes transfusion incompatibility
T9 317-342 other_name denotes newborn hemolytic disease
T10 348-361 protein_molecule denotes Duffy protein
T11 384-428 protein_molecule denotes Plasmodium vivax erythrocyte-binding protein
T12 464-474 protein_family_or_group denotes chemokines
T13 489-526 protein_molecule denotes Duffy Antigen Receptor for Chemokines
T14 528-532 protein_molecule denotes DARC
T15 544-570 protein_family_or_group denotes Duffy polymorphic antigens
T16 572-575 protein_molecule denotes Fya
T17 580-583 protein_molecule denotes Fyb
T18 637-658 protein_family_or_group denotes erythrocyte membranes
T19 664-682 other_name denotes Fy(a-b-) phenotype
T20 724-736 multi_cell denotes black people
T21 790-817 multi_cell denotes non-Ashkenazi Jewish groups
T22 823-841 other_name denotes Fy(a-b-) phenotype
T23 885-898 DNA_domain_or_region denotes FY*B promoter
T24 906-914 DNA_domain_or_region denotes GATA box
T25 948-959 protein_molecule denotes erythrocyte
T26 960-973 protein_molecule denotes Duffy protein
T27 994-1008 other_name denotes novel mutation
T28 1025-1045 DNA_domain_or_region denotes FY*B coding sequence
T29 1047-1051 nucleotide denotes 271C
T30 1056-1057 nucleotide denotes T
T31 1089-1106 other_name denotes Fy(b-) phenotypes
T32 1113-1131 multi_cell denotes non-Ashkenazi Jews
T33 1142-1158 multi_cell denotes Brazilian blacks
T34 1187-1205 multi_cell denotes Fy(b-) individuals
T35 1216-1235 DNA_domain_or_region denotes wild-type FY*B GATA
T36 1271-1275 nucleotide denotes 304G
T37 1280-1281 nucleotide denotes A
T38 1282-1294 other_name denotes substitution
T39 1300-1304 nucleotide denotes 271C
T40 1309-1310 nucleotide denotes T
T41 1315-1319 nucleotide denotes 304G
T42 1324-1325 nucleotide denotes A
T43 1347-1417 DNA_family_or_group denotes restriction enzyme-generated restriction fragment length polymorphisms
T44 1423-1427 nucleotide denotes 271C
T45 1432-1433 nucleotide denotes T
T46 1500-1505 amino_acid_monomer denotes Arg91
T47 1510-1513 amino_acid_monomer denotes Cys
T48 1567-1571 protein_molecule denotes DARC
T49 1678-1682 protein_molecule denotes DARC
T50 1705-1721 other_name denotes malaria research
T51 1740-1759 other_name denotes population genetics