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sentences

Id Subject Object Predicate Lexical cue
T1 0-121 Sentence denotes p130, p107, and pRb are differentially regulated in proliferating cells and during cell cycle arrest by alpha-interferon.
T2 122-424 Sentence denotes We have determined how the phosphorylation of the retinoblastoma family (pRb, p107, and p130) is governed in individual cell cycle phases of Daudi B-cells during cell cycle exit triggered by alpha-interferon (alpha-IFN). alpha-IFN causes dephosphorylation of pRb and loss of p130 phosphorylated Form 3.
T3 425-681 Sentence denotes However, the change in p130 phosphorylation in response to alpha-IFN occurs before dephosphorylation of pRb is complete because loss of p130 Form 3 occurs throughout the cell cycle prior to complete arrest in G1, whereas pRb is dephosphorylated only in G1.
T4 682-930 Sentence denotes In contrast, p107 is dephosphorylated and is then depleted from cells as they exit the cell cycle. p130, predominantly in Form 1, and hypophosphorylated pRb bind an E2F DNA binding site; p130 complexes E2F-4, whereas pRb binds both E2F-4 and E2F-1.
T5 931-1095 Sentence denotes The phosphorylated forms of E2F-4 that bind to the E2F DNA site are different from hyperphosphorylated E2F-4, which predominates in primary hemopoietic cells in G0.
T6 1096-1347 Sentence denotes We conclude that although cell cycle arrest induced by alpha-IFN may be mediated in part by formation of a complex containing p130 and E2F-4, alpha-IFN does not induce hyperphosphorylation of E2F-4, which characterizes primary hemopoietic cells in G0.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-4 protein denotes p130
T2 6-10 protein denotes p107
T3 16-19 protein denotes pRb
T4 52-71 cell_type denotes proliferating cells
T5 104-120 protein denotes alpha-interferon
T6 172-193 protein denotes retinoblastoma family
T7 195-198 protein denotes pRb
T8 200-204 protein denotes p107
T9 210-214 protein denotes p130
T10 263-276 cell_line denotes Daudi B-cells
T11 313-329 protein denotes alpha-interferon
T12 331-340 protein denotes alpha-IFN
T13 343-352 protein denotes alpha-IFN
T14 381-384 protein denotes pRb
T15 397-423 protein denotes p130 phosphorylated Form 3
T16 448-452 protein denotes p130
T17 484-493 protein denotes alpha-IFN
T18 529-532 protein denotes pRb
T19 561-572 protein denotes p130 Form 3
T20 646-649 protein denotes pRb
T21 695-699 protein denotes p107
T22 781-785 protein denotes p130
T23 816-838 protein denotes hypophosphorylated pRb
T24 847-867 DNA denotes E2F DNA binding site
T25 869-873 protein denotes p130
T26 884-889 protein denotes E2F-4
T27 899-902 protein denotes pRb
T28 924-929 protein denotes E2F-1
T29 959-964 protein denotes E2F-4
T30 982-994 DNA denotes E2F DNA site
T31 1034-1039 protein denotes E2F-4
T32 1063-1088 cell_type denotes primary hemopoietic cells
T33 1151-1160 protein denotes alpha-IFN
T34 1222-1226 protein denotes p130
T35 1231-1236 protein denotes E2F-4
T36 1238-1247 protein denotes alpha-IFN
T37 1288-1293 protein denotes E2F-4
T38 1315-1340 cell_type denotes primary hemopoietic cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-121 Sentence denotes p130, p107, and pRb are differentially regulated in proliferating cells and during cell cycle arrest by alpha-interferon.
S2 122-342 Sentence denotes We have determined how the phosphorylation of the retinoblastoma family (pRb, p107, and p130) is governed in individual cell cycle phases of Daudi B-cells during cell cycle exit triggered by alpha-interferon (alpha-IFN).
S3 343-424 Sentence denotes alpha-IFN causes dephosphorylation of pRb and loss of p130 phosphorylated Form 3.
S4 425-681 Sentence denotes However, the change in p130 phosphorylation in response to alpha-IFN occurs before dephosphorylation of pRb is complete because loss of p130 Form 3 occurs throughout the cell cycle prior to complete arrest in G1, whereas pRb is dephosphorylated only in G1.
S5 682-780 Sentence denotes In contrast, p107 is dephosphorylated and is then depleted from cells as they exit the cell cycle.
S6 781-930 Sentence denotes p130, predominantly in Form 1, and hypophosphorylated pRb bind an E2F DNA binding site; p130 complexes E2F-4, whereas pRb binds both E2F-4 and E2F-1.
S7 931-1095 Sentence denotes The phosphorylated forms of E2F-4 that bind to the E2F DNA site are different from hyperphosphorylated E2F-4, which predominates in primary hemopoietic cells in G0.
S8 1096-1347 Sentence denotes We conclude that although cell cycle arrest induced by alpha-IFN may be mediated in part by formation of a complex containing p130 and E2F-4, alpha-IFN does not induce hyperphosphorylation of E2F-4, which characterizes primary hemopoietic cells in G0.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 0-4 NP denotes p130
C3 6-10 NP denotes p107
C4 16-19 NP denotes pRb
C1 0-19 NP denotes p130, p107, and pRb
C6 104-120 NP denotes alpha-interferon
C5 83-120 NP denotes cell cycle arrest by alpha-interferon
C7 168-215 NP denotes the retinoblastoma family (pRb, p107, and p130)
C8 313-341 NP denotes alpha-interferon (alpha-IFN)
C9 343-352 NP denotes alpha-IFN
C11 381-384 NP denotes pRb
C10 360-384 NP denotes dephosphorylation of pRb
C12 389-423 NP denotes loss of p130 phosphorylated Form 3
C13 484-493 NP denotes alpha-IFN
C15 529-532 NP denotes pRb
C14 508-532 NP denotes dephosphorylation of pRb
C16 553-572 NP denotes loss of p130 Form 3
C17 591-605 NP denotes the cell cycle
C18 634-636 NP denotes G1
C19 646-649 NP denotes pRb
C20 678-680 NP denotes G1
C21 695-699 NP denotes p107
C22 746-751 NP denotes cells
C23 755-759 NP denotes they
C24 765-779 NP denotes the cell cycle
C25 781-785 NP denotes p130
C26 869-873 NP denotes p130
C27 884-889 NP denotes E2F-4
C28 899-902 NP denotes pRb
C30 959-964 NP denotes E2F-4
C29 931-964 NP denotes The phosphorylated forms of E2F-4
C31 965-969 NP denotes that
C32 1014-1039 NP denotes hyperphosphorylated E2F-4
C33 1041-1046 NP denotes which
C34 1063-1094 NP denotes primary hemopoietic cells in G0
C36 1151-1160 NP denotes alpha-IFN
C35 1122-1160 NP denotes cell cycle arrest induced by alpha-IFN
C37 1222-1226 NP denotes p130
C38 1231-1236 NP denotes E2F-4
C39 1238-1247 NP denotes alpha-IFN
C41 1288-1293 NP denotes E2F-4
C40 1264-1293 NP denotes hyperphosphorylation of E2F-4
C42 1295-1300 NP denotes which
C43 1315-1346 NP denotes primary hemopoietic cells in G0
R1 C7 C1 coref-ident "the retinoblastoma family (pRb, p107, and p130)","p130, p107, and pRb"
R2 C8 C6 coref-ident alpha-interferon (alpha-IFN),alpha-interferon
R3 C9 C8 coref-ident alpha-IFN,alpha-interferon (alpha-IFN)
R4 C11 C4 coref-ident pRb,pRb
R5 C13 C9 coref-ident alpha-IFN,alpha-IFN
R6 C15 C11 coref-ident pRb,pRb
R7 C14 C10 coref-ident dephosphorylation of pRb,dephosphorylation of pRb
R8 C16 C12 coref-ident loss of p130 Form 3,loss of p130 phosphorylated Form 3
R9 C19 C15 coref-ident pRb,pRb
R10 C20 C18 coref-ident G1,G1
R11 C21 C3 coref-ident p107,p107
R12 C23 C22 coref-pron they,cells
R13 C24 C17 coref-ident the cell cycle,the cell cycle
R14 C25 C2 coref-ident p130,p130
R15 C26 C25 coref-ident p130,p130
R16 C28 C19 coref-ident pRb,pRb
R17 C30 C27 coref-ident E2F-4,E2F-4
R18 C31 C29 coref-relat that,The phosphorylated forms of E2F-4
R19 C33 C32 coref-relat which,hyperphosphorylated E2F-4
R20 C36 C13 coref-ident alpha-IFN,alpha-IFN
R21 C35 C5 coref-ident cell cycle arrest induced by alpha-IFN,cell cycle arrest by alpha-interferon
R22 C37 C26 coref-ident p130,p130
R23 C38 C30 coref-ident E2F-4,E2F-4
R24 C39 C36 coref-ident alpha-IFN,alpha-IFN
R25 C41 C38 coref-ident E2F-4,E2F-4
R26 C42 C40 coref-relat which,hyperphosphorylation of E2F-4
R27 C43 C34 coref-ident primary hemopoietic cells in G0,primary hemopoietic cells in G0

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-4 protein_molecule denotes p130
T2 6-10 protein_molecule denotes p107
T3 16-19 protein_molecule denotes pRb
T4 52-71 cell_type denotes proliferating cells
T5 83-100 other_name denotes cell cycle arrest
T6 104-120 protein_molecule denotes alpha-interferon
T7 149-164 other_name denotes phosphorylation
T8 172-193 protein_family_or_group denotes retinoblastoma family
T9 195-198 protein_molecule denotes pRb
T10 200-204 protein_molecule denotes p107
T11 210-214 protein_molecule denotes p130
T12 263-276 cell_line denotes Daudi B-cells
T13 284-299 other_name denotes cell cycle exit
T14 313-329 protein_molecule denotes alpha-interferon
T15 331-340 protein_molecule denotes alpha-IFN
T16 343-352 protein_molecule denotes alpha-IFN
T17 381-384 protein_molecule denotes pRb
T18 397-401 protein_molecule denotes p130
T19 448-452 protein_molecule denotes p130
T20 484-493 protein_molecule denotes alpha-IFN
T21 529-532 protein_molecule denotes pRb
T22 561-565 protein_molecule denotes p130
T23 646-649 protein_molecule denotes pRb
T24 678-680 other_name denotes G1
T25 695-699 protein_molecule denotes p107
T26 781-785 protein_molecule denotes p130
T27 816-834 protein_molecule denotes hypophosphorylated
T28 835-838 protein_molecule denotes pRb
T29 847-867 DNA_domain_or_region denotes E2F DNA binding site
T30 869-873 protein_molecule denotes p130
T31 884-889 protein_molecule denotes E2F-4
T32 899-902 protein_molecule denotes pRb
T33 924-929 protein_molecule denotes E2F-1
T34 959-964 protein_molecule denotes E2F-4
T35 982-994 DNA_domain_or_region denotes E2F DNA site
T36 1034-1039 protein_molecule denotes E2F-4
T37 1063-1088 cell_type denotes primary hemopoietic cells
T38 1092-1094 other_name denotes G0
T39 1122-1139 other_name denotes cell cycle arrest
T40 1151-1160 protein_molecule denotes alpha-IFN
T41 1222-1226 protein_molecule denotes p130
T42 1231-1236 protein_molecule denotes E2F-4
T43 1238-1247 protein_molecule denotes alpha-IFN
T44 1264-1284 other_name denotes hyperphosphorylation
T45 1288-1293 protein_molecule denotes E2F-4
T46 1315-1340 cell_type denotes primary hemopoietic cells
T47 1344-1346 other_name denotes G0

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 172-186 Phenotype denotes retinoblastoma HP:0009919

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 172-186 Disease denotes retinoblastoma http://purl.obolibrary.org/obo/MONDO_0008380

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 83-93 Body_part denotes cell cycle http://purl.obolibrary.org/obo/UBERON_2000098
T2 242-252 Body_part denotes cell cycle http://purl.obolibrary.org/obo/UBERON_2000098
T3 284-294 Body_part denotes cell cycle http://purl.obolibrary.org/obo/UBERON_2000098
T4 595-605 Body_part denotes cell cycle http://purl.obolibrary.org/obo/UBERON_2000098
T5 769-779 Body_part denotes cell cycle http://purl.obolibrary.org/obo/UBERON_2000098
T6 1071-1088 Body_part denotes hemopoietic cells http://purl.obolibrary.org/obo/CL_0000988
T7 1122-1132 Body_part denotes cell cycle http://purl.obolibrary.org/obo/UBERON_2000098
T8 1323-1340 Body_part denotes hemopoietic cells http://purl.obolibrary.org/obo/CL_0000988

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 269-276 Cell denotes B-cells http://purl.obolibrary.org/obo/CL:0000236
T2 1071-1088 Cell denotes hemopoietic cells http://purl.obolibrary.org/obo/CL:0000988
T3 1323-1340 Cell denotes hemopoietic cells http://purl.obolibrary.org/obo/CL:0000988