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sentences

Id Subject Object Predicate Lexical cue
T1 0-123 Sentence denotes The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB.
T2 124-284 Sentence denotes Forkhead-related activator 2 (FREAC-2) is a human transcription factor expressed in lung and placenta that binds to cis-elements in several lung-specific genes.
T3 285-472 Sentence denotes We have identified the parts of FREAC-2 responsible for trans-activation and found two functionally redundant activation domains on the C-terminal side of the DNA binding forkhead domain.
T4 473-652 Sentence denotes Activation domain 1 consists of the most C-terminal 23 amino acids of FREAC-2 and contains a sequence motif conserved in an activation domain of another forkhead protein, FREAC-1.
T5 653-760 Sentence denotes Activation domain 2 is built up by three synergistic subdomains in the central part of the FREAC-2 protein.
T6 761-819 Sentence denotes FREAC-2 was shown to interact in vitro with TBP and TFIIB.
T7 820-920 Sentence denotes The target site for FREAC-2 on TBP was localized to the N-terminal repeat in the core domain of TBP.
T8 921-993 Sentence denotes TFIIB binds FREAC-2 close to the cleft between its two globular domains.
T9 994-1103 Sentence denotes The part of FREAC-2 that binds TBP was mapped to 21 amino acids in the C-terminal end of the forkhead domain.
T10 1104-1283 Sentence denotes This sequence is well conserved among forkhead proteins, raising the possibility that interaction with TBP may be a general characteristic of this family of transcription factors.
T11 1284-1398 Sentence denotes Overexpression of TFIIB potentiates activation by FREAC-2 in a manner dependent on the FREAC-2 activation domains.
T12 1399-1502 Sentence denotes Nuclear localization of FREAC-2 was found to depend on sequences from both ends of the forkhead domain.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 208-212 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung
T2 217-225 http://purl.obolibrary.org/obo/MAT_0000279 denotes placenta
T3 264-268 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

bionlp-st-gro-2013-development

Id Subject Object Predicate Lexical cue
T1 4-9 Eukaryote denotes human
T2 10-34 ForkheadWingedHelixTF denotes forkhead protein FREAC-2
T4 82-89 ProteinDomain denotes domains
T6 109-112 Protein denotes TBP
T7 117-122 Protein denotes TFIIB
T8 124-152 ForkheadWingedHelixTF denotes Forkhead-related activator 2
T9 154-161 ForkheadWingedHelixTF denotes FREAC-2
T10 168-173 Eukaryote denotes human
T11 174-194 TranscriptionFactor denotes transcription factor
T13 208-212 Tissue denotes lung
T14 217-225 Tissue denotes placenta
T16 240-252 DNARegion denotes cis-elements
T17 264-268 Tissue denotes lung
T18 278-283 Gene denotes genes
T19 317-324 ForkheadWingedHelixTF denotes FREAC-2
T22 406-413 ProteinDomain denotes domains
T23 444-471 ForkheadWingedHelix denotes DNA binding forkhead domain
T25 484-492 ProteinDomain denotes domain 1
T26 528-539 AminoAcid denotes amino acids
T27 543-550 ForkheadWingedHelixTF denotes FREAC-2
T28 566-580 Peptide denotes sequence motif
T30 608-614 ProteinDomain denotes domain
T31 626-642 ForkheadWingedHelixTF denotes forkhead protein
T32 644-651 ForkheadWingedHelixTF denotes FREAC-1
T34 664-672 ProteinDomain denotes domain 2
T35 706-716 ProteinDomain denotes subdomains
T36 744-759 ForkheadWingedHelixTF denotes FREAC-2 protein
T37 761-768 ForkheadWingedHelixTF denotes FREAC-2
T39 805-808 Protein denotes TBP
T40 813-818 Protein denotes TFIIB
T41 824-835 ProteinBindingSiteOfProtein denotes target site
T42 840-847 ForkheadWingedHelixTF denotes FREAC-2
T43 851-854 Protein denotes TBP
T45 901-912 ProteinDomain denotes core domain
T46 916-919 Protein denotes TBP
T47 921-926 Protein denotes TFIIB
T49 933-940 ForkheadWingedHelixTF denotes FREAC-2
T50 976-992 ProteinDomain denotes globular domains
T51 998-1002 ProteinDomain denotes part
T52 1006-1013 ForkheadWingedHelixTF denotes FREAC-2
T54 1025-1028 Protein denotes TBP
T55 1046-1057 AminoAcid denotes amino acids
T56 1087-1102 ForkheadWingedHelix denotes forkhead domain
T57 1142-1159 ForkheadWingedHelixTF denotes forkhead proteins
T59 1207-1210 Protein denotes TBP
T60 1261-1282 TranscriptionFactor denotes transcription factors
T62 1302-1307 Protein denotes TFIIB
T64 1334-1341 ForkheadWingedHelixTF denotes FREAC-2
T65 1371-1378 ForkheadWingedHelixTF denotes FREAC-2
T67 1390-1397 ProteinDomain denotes domains
T68 1399-1406 Nucleus denotes Nuclear
T70 1423-1430 ForkheadWingedHelixTF denotes FREAC-2
T71 1486-1501 ForkheadWingedHelix denotes forkhead domain
E1 71-81 PositiveRegulation denotes activation
E2 94-103 BindingToProtein denotes interacts
E3 195-204 GeneExpression denotes expressed
E4 231-236 BindingOfProteinToDNA denotes binds
E5 341-357 PositiveRegulation denotes trans-activation
E6 395-405 PositiveRegulation denotes activation
E7 473-483 PositiveRegulation denotes Activation
E8 597-607 PositiveRegulation denotes activation
E9 653-663 PositiveRegulation denotes Activation
E11 859-868 Localization denotes localized
E12 927-932 BindingToProtein denotes binds
E13 1019-1024 BindingToProtein denotes binds
E14 1190-1201 BindingToProtein denotes interaction
E15 1284-1298 PositiveRegulationOfGeneExpression denotes Overexpression
E16 1320-1330 PositiveRegulation denotes activation
E17 1379-1389 PositiveRegulation denotes activation
E18 1407-1419 Localization denotes localization
E20 782-790 BindingToProtein denotes interact
R1 T2 T4 hasPart forkhead protein FREAC-2,domains
R2 T2 T1 fromSpecies forkhead protein FREAC-2,human
R4 E3 T13 locatedIn expressed,lung
R5 E3 T14 locatedIn expressed,placenta
R6 T18 T17 locatedIn genes,lung
R7 T18 T16 hasPart genes,cis-elements
R8 T23 T22 hasPart DNA binding forkhead domain,domains
R9 T25 T26 hasPart domain 1,amino acids
R10 T25 T28 hasPart domain 1,sequence motif
R11 T27 T26 hasPart FREAC-2,amino acids
R12 T30 T28 hasPart domain,sequence motif
R13 T32 T30 hasPart FREAC-1,domain
R14 T34 T35 hasPart domain 2,subdomains
R15 T36 T34 hasPart FREAC-2 protein,domain 2
R16 T43 T41 hasPart TBP,target site
R17 E11 T45 locatedIn localized,core domain
R18 T46 T45 hasPart TBP,core domain
R20 T52 T51 hasPart FREAC-2,part
R21 T56 T55 hasPart forkhead domain,amino acids
R23 T65 T67 hasPart FREAC-2,domains
R24 E18 T68 locatedIn localization,Nuclear
R3 T9 T10 fromSpecies FREAC-2,human
R5 T4 E1 hasAgent domains,activation
R6 T6 E2 hasPatient TBP,interacts
R7 T7 E2 hasPatient TFIIB,interacts
R8 T2 E2 hasPatient forkhead protein FREAC-2,interacts
R9 T9 E3 hasPatient FREAC-2,expressed
R10 T16 E4 hasPatient cis-elements,binds
R11 T19 E5 hasAgent FREAC-2,trans-activation
R12 T22 E6 hasAgent domains,activation
R13 T25 E7 hasAgent domain 1,Activation
R14 T30 E8 hasAgent domain,activation
R15 T34 E9 hasAgent domain 2,Activation
R16 T41 E11 hasPatient target site,localized
R17 T49 E12 hasPatient FREAC-2,binds
R18 T47 E12 hasPatient TFIIB,binds
R19 T54 E13 hasPatient TBP,binds
R20 T51 E13 hasPatient part,binds
R21 T59 E14 hasPatient TBP,interaction
R22 T60 E14 hasPatient transcription factors,interaction
R23 T62 E15 hasPatient TFIIB,Overexpression
R24 T64 E16 hasAgent FREAC-2,activation
R25 T67 E17 hasAgent domains,activation
R26 T70 E18 hasPatient FREAC-2,localization
R27 T37 E20 hasPatient FREAC-2,interact
R28 T39 E20 hasPatient TBP,interact
R29 T40 E20 hasPatient TFIIB,interact

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 208-212 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135
T2 217-225 Body_part denotes placenta http://purl.obolibrary.org/obo/MAT_0000279
T3 264-268 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 4-9 OrganismTaxon denotes human 9606
T2 168-173 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 208-212 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 217-225 Body_part denotes placenta http://purl.obolibrary.org/obo/UBERON_0001987
T3 264-268 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048