PubMed:9663467
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-14 | protein | denotes | Thrombopoietin |
| T2 | 85-90 | protein | denotes | c-Mpl |
| T3 | 96-120 | cell_line | denotes | human leukemia cell line |
| T4 | 122-136 | protein | denotes | Thrombopoietin |
| T5 | 138-141 | protein | denotes | TPO |
| T6 | 238-246 | cell_line | denotes | UT-7/GMT |
| T7 | 257-289 | cell_line | denotes | human leukemia cell line UT-7/GM |
| T8 | 362-375 | cell_line | denotes | UT-7/GM cells |
| T9 | 399-409 | protein | denotes | hemoglobin |
| T10 | 411-413 | protein | denotes | Hb |
| T11 | 441-444 | protein | denotes | TPO |
| T12 | 463-489 | cell_line | denotes | TPO-treated UT-7/GMT cells |
| T13 | 513-515 | protein | denotes | Hb |
| T14 | 523-537 | cell_line | denotes | UT-7/GMT cells |
| T15 | 555-558 | protein | denotes | TPO |
| T16 | 587-590 | protein | denotes | TPO |
| T17 | 631-634 | protein | denotes | TPO |
| T18 | 656-685 | protein | denotes | erythropoietin (EPO) receptor |
| T19 | 720-723 | protein | denotes | TPO |
| T20 | 728-731 | protein | denotes | EPO |
| T21 | 747-759 | protein | denotes | EPO receptor |
| T22 | 789-792 | protein | denotes | TPO |
| T23 | 861-875 | cell_line | denotes | UT-7/GMT cells |
| T24 | 916-919 | protein | denotes | TPO |
| T25 | 966-969 | protein | denotes | EPO |
| T26 | 1048-1051 | protein | denotes | TPO |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-14 | NP | denotes | Thrombopoietin |
| C2 | 63-66 | NP | denotes | its |
| C3 | 94-120 | NP | denotes | a human leukemia cell line |
| C4 | 122-142 | NP | denotes | Thrombopoietin (TPO) |
| C5 | 172-186 | NP | denotes | erythropoiesis |
| C6 | 223-236 | NP | denotes | novel subline |
| C7 | 238-246 | NP | denotes | UT-7/GMT |
| C8 | 253-289 | NP | denotes | the human leukemia cell line UT-7/GM |
| C9 | 362-375 | NP | denotes | UT-7/GM cells |
| C10 | 399-414 | NP | denotes | hemoglobin (Hb) |
| C11 | 441-444 | NP | denotes | TPO |
| C12 | 513-515 | NP | denotes | Hb |
| C13 | 523-537 | NP | denotes | UT-7/GMT cells |
| C14 | 555-558 | NP | denotes | TPO |
| C15 | 587-590 | NP | denotes | TPO |
| C16 | 652-685 | NP | denotes | the erythropoietin (EPO) receptor |
| C17 | 720-723 | NP | denotes | TPO |
| C18 | 747-759 | NP | denotes | EPO receptor |
| C19 | 789-792 | NP | denotes | TPO |
| C20 | 861-875 | NP | denotes | UT-7/GMT cells |
| C21 | 916-919 | NP | denotes | TPO |
| C22 | 1048-1051 | NP | denotes | TPO |
| C23 | 1077-1091 | NP | denotes | erythropoiesis |
| R1 | C2 | C1 | coref-pron | its,Thrombopoietin |
| R2 | C4 | C1 | coref-ident | Thrombopoietin (TPO),Thrombopoietin |
| R3 | C7 | C6 | coref-appos | UT-7/GMT,novel subline |
| R4 | C8 | C3 | coref-ident | the human leukemia cell line UT-7/GM,a human leukemia cell line |
| R5 | C11 | C4 | coref-ident | TPO,Thrombopoietin (TPO) |
| R6 | C12 | C10 | coref-ident | Hb,hemoglobin (Hb) |
| R7 | C13 | C9 | coref-ident | UT-7/GMT cells,UT-7/GM cells |
| R8 | C14 | C11 | coref-ident | TPO,TPO |
| R9 | C15 | C14 | coref-ident | TPO,TPO |
| R10 | C17 | C15 | coref-ident | TPO,TPO |
| R11 | C18 | C16 | coref-ident | EPO receptor,the erythropoietin (EPO) receptor |
| R12 | C19 | C17 | coref-ident | TPO,TPO |
| R13 | C20 | C13 | coref-ident | UT-7/GMT cells,UT-7/GMT cells |
| R14 | C21 | C19 | coref-ident | TPO,TPO |
| R15 | C22 | C21 | coref-ident | TPO,TPO |
| R16 | C23 | C5 | coref-ident | erythropoiesis,erythropoiesis |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-121 | Sentence | denotes | Thrombopoietin supports in vitro erythroid differentiation via its specific receptor c-Mpl in a human leukemia cell line. |
| S2 | 122-208 | Sentence | denotes | Thrombopoietin (TPO) acts on megakaryopoiesis and erythropoiesis in vitro and in vivo. |
| S3 | 209-339 | Sentence | denotes | We isolated a novel subline, UT-7/GMT, from the human leukemia cell line UT-7/GM (N. Komatsu, et al., Blood, 89: 4021-4033, 1997). |
| S4 | 340-445 | Sentence | denotes | A small population of UT-7/GM cells positively stained for hemoglobin (Hb) after a 7-day exposure to TPO. |
| S5 | 446-516 | Sentence | denotes | More than 50% of TPO-treated UT-7/GMT cells positively stained for Hb. |
| S6 | 517-586 | Sentence | denotes | Using UT-7/GMT cells, we examined how TPO promotes hemoglobinization. |
| S7 | 587-686 | Sentence | denotes | TPO induced tyrosine phosphorylation of the TPO receptor but not the erythropoietin (EPO) receptor. |
| S8 | 687-760 | Sentence | denotes | There was no competition between TPO and EPO for binding to EPO receptor. |
| S9 | 761-876 | Sentence | denotes | These findings suggest that TPO has a direct effect on hemoglobinization via a specific receptor on UT-7/GMT cells. |
| S10 | 877-1019 | Sentence | denotes | Isoelectric focusing demonstrated that TPO induced fetal and adult Hb synthesis, whereas EPO induced embryonic, fetal, and adult Hb synthesis. |
| S11 | 1020-1092 | Sentence | denotes | Thus, our data suggest that TPO has a distinct action on erythropoiesis. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-14 | protein_molecule | denotes | Thrombopoietin |
| T2 | 24-42 | other_name | denotes | in vitro erythroid |
| T3 | 43-58 | other_name | denotes | differentiation |
| T4 | 85-90 | protein_molecule | denotes | c-Mpl |
| T5 | 96-120 | cell_line | denotes | human leukemia cell line |
| T6 | 122-136 | protein_molecule | denotes | Thrombopoietin |
| T7 | 138-141 | protein_molecule | denotes | TPO |
| T8 | 151-167 | other_name | denotes | megakaryopoiesis |
| T9 | 172-186 | other_name | denotes | erythropoiesis |
| T10 | 238-246 | cell_line | denotes | UT-7/GMT |
| T11 | 257-281 | cell_line | denotes | human leukemia cell line |
| T12 | 362-375 | cell_line | denotes | UT-7/GM cells |
| T13 | 399-409 | protein_complex | denotes | hemoglobin |
| T14 | 411-413 | protein_complex | denotes | Hb |
| T15 | 441-444 | protein_molecule | denotes | TPO |
| T16 | 463-466 | protein_molecule | denotes | TPO |
| T17 | 513-515 | protein_complex | denotes | Hb |
| T18 | 523-537 | cell_line | denotes | UT-7/GMT cells |
| T19 | 555-558 | protein_molecule | denotes | TPO |
| T20 | 568-585 | other_name | denotes | hemoglobinization |
| T21 | 587-590 | protein_molecule | denotes | TPO |
| T22 | 599-607 | amino_acid_monomer | denotes | tyrosine |
| T23 | 631-634 | protein_molecule | denotes | TPO |
| T24 | 656-672 | protein_family_or_group | denotes | erythropoietin ( |
| T25 | 672-675 | protein_molecule | denotes | EPO |
| T26 | 720-723 | protein_molecule | denotes | TPO |
| T27 | 728-731 | protein_molecule | denotes | EPO |
| T28 | 747-750 | protein_molecule | denotes | EPO |
| T29 | 789-792 | protein_molecule | denotes | TPO |
| T30 | 861-875 | cell_line | denotes | UT-7/GMT cells |
| T31 | 877-897 | other_name | denotes | Isoelectric focusing |
| T32 | 916-919 | protein_molecule | denotes | TPO |
| T33 | 966-969 | protein_molecule | denotes | EPO |
| T34 | 1048-1051 | protein_molecule | denotes | TPO |
| T35 | 1077-1091 | other_name | denotes | erythropoiesis |