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PubMed:9653834 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-90 Sentence denotes Metalloproteinase-9 mRNA expression in monocytes from patients with chronic renal failure.
TextSentencer_T2 91-179 Sentence denotes Long-term dialysis patients suffer from various complications including atherosclerosis.
TextSentencer_T3 180-331 Sentence denotes It has been suggested that metalloproteinases (MMPs) contribute to vascular remodeling during the development and progression of human atherosclerosis.
TextSentencer_T4 332-397 Sentence denotes Activated human monocytes have been demonstrated to secrete MMPs.
TextSentencer_T5 398-636 Sentence denotes In the present study, we measured levels of MMP mRNA in peripheral blood monocytes obtained from patients on continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis (HD) and chronic-renal-failure patients not undergoing dialysis.
TextSentencer_T6 637-812 Sentence denotes Twenty patients with chronic renal failure were not undergoing dialysis, 20 patients were on CAPD, 40 patients were on chronic HD and 20 healthy volunteers served as controls.
TextSentencer_T7 813-919 Sentence denotes We used cDNA probes encoding for MMP-1, MMP-2, MMP-3 and MMP-9 and glyceraldehyde phosphate dehydrogenase.
TextSentencer_T8 920-1096 Sentence denotes Higher levels of MMP-9 mRNA in the peripheral blood monocytes were observed in HD patients than in CAPD patients, undialyzed chronic renal failure patients or healthy controls.
TextSentencer_T9 1097-1192 Sentence denotes MMP-9 mRNA levels at the end of HD were not significantly higher than those at the start of HD.
TextSentencer_T10 1193-1272 Sentence denotes MMP-9 mRNA levels from HD patients did not differ among the types of membranes.
TextSentencer_T11 1273-1365 Sentence denotes We could detect minimal MMP-1, MMP-2 and MMP-3 mRNA expression in monocytes from all groups.
TextSentencer_T12 1366-1484 Sentence denotes Serum gelatinase activity was detectable in all samples; however, no significant differences existed among the groups.
TextSentencer_T13 1485-1702 Sentence denotes In summary, MMP-9 mRNA expression is enhanced in monocytes from HD and CAPD patients, and the enhancement may be, in part, associated with cardiovascular complications, including atherosclerosis, in dialysis patients.
TextSentencer_T14 1703-1799 Sentence denotes This increase in monocyte MMP-9 mRNA levels is lower in CAPD patients that it is in HD patients.
T1 0-90 Sentence denotes Metalloproteinase-9 mRNA expression in monocytes from patients with chronic renal failure.
T2 91-179 Sentence denotes Long-term dialysis patients suffer from various complications including atherosclerosis.
T3 180-331 Sentence denotes It has been suggested that metalloproteinases (MMPs) contribute to vascular remodeling during the development and progression of human atherosclerosis.
T4 332-397 Sentence denotes Activated human monocytes have been demonstrated to secrete MMPs.
T5 398-636 Sentence denotes In the present study, we measured levels of MMP mRNA in peripheral blood monocytes obtained from patients on continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis (HD) and chronic-renal-failure patients not undergoing dialysis.
T6 637-812 Sentence denotes Twenty patients with chronic renal failure were not undergoing dialysis, 20 patients were on CAPD, 40 patients were on chronic HD and 20 healthy volunteers served as controls.
T7 813-919 Sentence denotes We used cDNA probes encoding for MMP-1, MMP-2, MMP-3 and MMP-9 and glyceraldehyde phosphate dehydrogenase.
T8 920-1096 Sentence denotes Higher levels of MMP-9 mRNA in the peripheral blood monocytes were observed in HD patients than in CAPD patients, undialyzed chronic renal failure patients or healthy controls.
T9 1097-1192 Sentence denotes MMP-9 mRNA levels at the end of HD were not significantly higher than those at the start of HD.
T10 1193-1272 Sentence denotes MMP-9 mRNA levels from HD patients did not differ among the types of membranes.
T11 1273-1365 Sentence denotes We could detect minimal MMP-1, MMP-2 and MMP-3 mRNA expression in monocytes from all groups.
T12 1366-1484 Sentence denotes Serum gelatinase activity was detectable in all samples; however, no significant differences existed among the groups.
T13 1485-1702 Sentence denotes In summary, MMP-9 mRNA expression is enhanced in monocytes from HD and CAPD patients, and the enhancement may be, in part, associated with cardiovascular complications, including atherosclerosis, in dialysis patients.
T14 1703-1799 Sentence denotes This increase in monocyte MMP-9 mRNA levels is lower in CAPD patients that it is in HD patients.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 937-942 gene:4318 denotes MMP-9
T1 999-1001 disease:C0019829 denotes HD
T2 937-942 gene:4318 denotes MMP-9
T3 999-1001 disease:C0020179 denotes HD
R1 T0 T1 associated_with MMP-9,HD
R2 T2 T3 associated_with MMP-9,HD

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 465-470 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 966-971 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 465-470 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 966-971 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T3 1366-1371 http://purl.obolibrary.org/obo/UBERON_0001977 denotes Serum

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2689 1497-1502 gene:4318 denotes MMP-9
T2690 1664-1679 disease:C0003850 denotes atherosclerosis
T2691 1729-1734 gene:4318 denotes MMP-9
T2692 1787-1789 disease:C0019829 denotes HD
R1 T2689 T2690 associated_with MMP-9,atherosclerosis
R2 T2689 T2690 associated_with MMP-9,atherosclerosis
R3 T2691 T2692 associated_with MMP-9,HD
R4 T2691 T2692 associated_with MMP-9,HD