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PubMed:9647766 JSONTXT

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LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
229 66-71 OrganismTaxon denotes human NCBITaxon:9606
230 72-135 GeneOrGeneProduct denotes nuclear encoded iron sulphur protein (IP) subunits of complex I NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
231 141-146 OrganismTaxon denotes human NCBITaxon:9606
232 147-149 GeneOrGeneProduct denotes IP NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
233 173-215 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase (complex I) NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
234 278-290 GeneOrGeneProduct denotes flavoprotein
235 292-294 GeneOrGeneProduct denotes FP
236 297-316 GeneOrGeneProduct denotes iron-sulfur protein NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
237 318-320 GeneOrGeneProduct denotes IP NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
238 327-346 GeneOrGeneProduct denotes hydrophobic protein
239 348-350 GeneOrGeneProduct denotes HP
240 369-371 GeneOrGeneProduct denotes IP NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
241 535-540 OrganismTaxon denotes human NCBITaxon:9606
242 541-580 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase subunits NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
243 589-591 GeneOrGeneProduct denotes IP NCBIGene:4720|NCBIGene:4722|NCBIGene:4726
244 606-612 GeneOrGeneProduct denotes NDUFS2 NCBIGene:4720
245 623-629 GeneOrGeneProduct denotes NDUFS3 NCBIGene:4722
246 644-650 GeneOrGeneProduct denotes NDUFS6 NCBIGene:4726
247 905-911 OrganismTaxon denotes bovine NCBITaxon:9913
248 1068-1073 OrganismTaxon denotes human NCBITaxon:9606
249 1113-1118 OrganismTaxon denotes human NCBITaxon:9606
250 1150-1155 OrganismTaxon denotes human NCBITaxon:9606
251 1189-1195 GeneOrGeneProduct denotes NDUFS2 NCBIGene:4720
252 1200-1206 GeneOrGeneProduct denotes NDUFS3 NCBIGene:4722
253 1274-1280 GeneOrGeneProduct denotes NDUFS6 NCBIGene:4726
254 1390-1396 GeneOrGeneProduct denotes NDUFS2 NCBIGene:4720
255 1425-1441 GeneOrGeneProduct denotes protein kinase C NCBIGene:5578
256 1471-1477 GeneOrGeneProduct denotes NDUFS3 NCBIGene:4722
257 1514-1530 GeneOrGeneProduct denotes casein kinase II NCBIGene:1457
258 1627-1656 DiseaseOrPhenotypicFeature denotes enzymatic complex I-deficient MESH:C537475
259 1657-1665 OrganismTaxon denotes patients NCBITaxon:9606

LitCoin-entities-OrganismTaxon-PD

Id Subject Object Predicate Lexical cue db_id
T1 66-71 OrganismTaxon denotes human NCBItxid:9606
T2 141-146 OrganismTaxon denotes human NCBItxid:9606
T3 535-540 OrganismTaxon denotes human NCBItxid:9606
T4 905-911 OrganismTaxon denotes bovine NCBItxid:9913
T5 1068-1073 OrganismTaxon denotes human NCBItxid:9606
T6 1074-1080 OrganismTaxon denotes rodent NCBItxid:9989
T7 1113-1118 OrganismTaxon denotes human NCBItxid:9606
T8 1150-1155 OrganismTaxon denotes human NCBItxid:9606

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-172 Sentence denotes cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.
T2 173-364 Sentence denotes NADH:ubiquinone oxidoreductase (complex I) of the mitochondrial respiratory chain can be fragmented in a flavoprotein (FP), iron-sulfur protein (IP), and hydrophobic protein (HP) subfraction.
T3 365-496 Sentence denotes The IP subfraction is hypothesized to be significant, since it contains important prosthetic groups highly conserved among species.
T4 497-669 Sentence denotes We cloned the cDNA of three remaining human NADH:ubiquinone oxidoreductase subunits of this IP fraction: the NDUFS2 (49 kDa), NDUFS3 (30 kDa), and NDUFS6 (13 kDa) subunits.
T5 670-840 Sentence denotes All presented cDNAs include the complete open reading frame (ORF), which consist of 1392, 795, and 375 base pairs, coding for 463, 264, and 124 amino acids, respectively.
T6 841-933 Sentence denotes The latter show 96, 90, and 83% homology with the corresponding bovine translation products.
T7 934-1000 Sentence denotes The 3' untranslated regions (UTR) are complete in all three cDNAs.
T8 1001-1254 Sentence denotes Polymerase chain reaction performed with DNA isolated from somatic human-rodent cell hybrids containing defined human chromosomes as template gave a human-specific signal which mapped the NDUFS2 and NDUFS3 subunits to chromosomes 1 and 11, respectively.
T9 1255-1385 Sentence denotes In the case of the NDUFS6 subunit a pseudogene may be present since signals were seen in the lanes containing chromosomes 5 and 6.
T10 1386-1666 Sentence denotes The NDUFS2 contains a highly conserved protein kinase C phosphorylation site and the NDUFS3 subunit contains a highly conserved casein kinase II phosphorylation site which make them strong candidates for future mutation detection studies in enzymatic complex I-deficient patients.

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 162-171 DiseaseOrPhenotypicFeature denotes completed 0700063
T2 702-710 DiseaseOrPhenotypicFeature denotes complete 0700063
T3 972-980 DiseaseOrPhenotypicFeature denotes complete 0700063

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-4 GeneOrGeneProduct denotes cDNA
T2 88-92 GeneOrGeneProduct denotes iron
T3 101-108 GeneOrGeneProduct denotes protein
T4 173-215 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase (complex I)
T5 223-236 GeneOrGeneProduct denotes mitochondrial
T6 249-254 GeneOrGeneProduct denotes chain
T7 262-277 GeneOrGeneProduct denotes fragmented in a
T8 278-290 GeneOrGeneProduct denotes flavoprotein
T9 292-294 GeneOrGeneProduct denotes FP
T10 297-316 GeneOrGeneProduct denotes iron-sulfur protein
T11 327-346 GeneOrGeneProduct denotes hydrophobic protein
T12 348-350 GeneOrGeneProduct denotes HP
T13 465-471 GeneOrGeneProduct denotes highly
T14 472-481 GeneOrGeneProduct denotes conserved
T15 500-510 GeneOrGeneProduct denotes cloned the
T16 511-515 GeneOrGeneProduct denotes cDNA
T17 541-571 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase
T18 606-612 GeneOrGeneProduct denotes NDUFS2
T19 623-629 GeneOrGeneProduct denotes NDUFS3
T20 631-637 GeneOrGeneProduct denotes 30 kDa
T21 644-650 GeneOrGeneProduct denotes NDUFS6
T22 652-658 GeneOrGeneProduct denotes 13 kDa
T23 670-673 GeneOrGeneProduct denotes All
T24 711-729 GeneOrGeneProduct denotes open reading frame
T25 731-734 GeneOrGeneProduct denotes ORF
T26 773-777 GeneOrGeneProduct denotes base
T27 778-783 GeneOrGeneProduct denotes pairs
T28 814-825 GeneOrGeneProduct denotes amino acids
T29 873-881 GeneOrGeneProduct denotes homology
T30 924-932 GeneOrGeneProduct denotes products
T31 984-987 GeneOrGeneProduct denotes all
T32 1001-1011 GeneOrGeneProduct denotes Polymerase
T33 1012-1017 GeneOrGeneProduct denotes chain
T34 1081-1085 GeneOrGeneProduct denotes cell
T35 1189-1195 GeneOrGeneProduct denotes NDUFS2
T36 1200-1206 GeneOrGeneProduct denotes NDUFS3
T37 1231-1236 GeneOrGeneProduct denotes 1 and
T38 1262-1266 GeneOrGeneProduct denotes case
T39 1274-1280 GeneOrGeneProduct denotes NDUFS6
T40 1281-1290 GeneOrGeneProduct denotes subunit a
T41 1291-1301 GeneOrGeneProduct denotes pseudogene
T42 1390-1396 GeneOrGeneProduct denotes NDUFS2
T43 1408-1414 GeneOrGeneProduct denotes highly
T44 1415-1439 GeneOrGeneProduct denotes conserved protein kinase
T45 1471-1477 GeneOrGeneProduct denotes NDUFS3
T46 1497-1503 GeneOrGeneProduct denotes highly
T47 1504-1513 GeneOrGeneProduct denotes conserved
T48 1514-1530 GeneOrGeneProduct denotes casein kinase II
T49 1563-1567 GeneOrGeneProduct denotes them
T50 1597-1605 GeneOrGeneProduct denotes mutation

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 0-4 GeneOrGeneProduct denotes cDNA
T2 101-108 GeneOrGeneProduct denotes protein
T3 173-215 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase (complex I)
T4 223-236 GeneOrGeneProduct denotes mitochondrial
T5 249-254 GeneOrGeneProduct denotes chain
T6 278-290 GeneOrGeneProduct denotes flavoprotein
T7 292-294 GeneOrGeneProduct denotes FP
T8 297-316 GeneOrGeneProduct denotes iron-sulfur protein
T9 327-346 GeneOrGeneProduct denotes hydrophobic protein
T10 348-350 GeneOrGeneProduct denotes HP
T11 472-481 GeneOrGeneProduct denotes conserved
T12 511-515 GeneOrGeneProduct denotes cDNA
T13 541-571 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase
T14 606-612 GeneOrGeneProduct denotes NDUFS2
T15 623-629 GeneOrGeneProduct denotes NDUFS3
T16 631-637 GeneOrGeneProduct denotes 30 kDa
T17 644-650 GeneOrGeneProduct denotes NDUFS6
T18 652-658 GeneOrGeneProduct denotes 13 kDa
T19 711-729 GeneOrGeneProduct denotes open reading frame
T20 731-734 GeneOrGeneProduct denotes ORF
T21 814-825 GeneOrGeneProduct denotes amino acids
T22 1001-1011 GeneOrGeneProduct denotes Polymerase
T23 1012-1017 GeneOrGeneProduct denotes chain
T24 1081-1085 GeneOrGeneProduct denotes cell
T25 1189-1195 GeneOrGeneProduct denotes NDUFS2
T26 1200-1206 GeneOrGeneProduct denotes NDUFS3
T27 1274-1280 GeneOrGeneProduct denotes NDUFS6
T28 1281-1290 GeneOrGeneProduct denotes subunit a
T29 1291-1301 GeneOrGeneProduct denotes pseudogene
T30 1390-1396 GeneOrGeneProduct denotes NDUFS2
T31 1415-1439 GeneOrGeneProduct denotes conserved protein kinase
T32 1471-1477 GeneOrGeneProduct denotes NDUFS3
T33 1504-1513 GeneOrGeneProduct denotes conserved
T34 1514-1530 GeneOrGeneProduct denotes casein kinase II

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 525-540 DiseaseOrPhenotypicFeature denotes remaining human D000071298

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 173-215 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase (complex I)
T2 278-290 GeneOrGeneProduct denotes flavoprotein
T3 292-294 GeneOrGeneProduct denotes FP
T4 297-316 GeneOrGeneProduct denotes iron-sulfur protein
T5 327-346 GeneOrGeneProduct denotes hydrophobic protein
T6 348-350 GeneOrGeneProduct denotes HP
T7 541-571 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase
T8 606-612 GeneOrGeneProduct denotes NDUFS2
T9 623-629 GeneOrGeneProduct denotes NDUFS3
T10 631-637 GeneOrGeneProduct denotes 30 kDa
T11 644-650 GeneOrGeneProduct denotes NDUFS6
T12 652-658 GeneOrGeneProduct denotes 13 kDa
T13 1189-1195 GeneOrGeneProduct denotes NDUFS2
T14 1200-1206 GeneOrGeneProduct denotes NDUFS3
T15 1274-1280 GeneOrGeneProduct denotes NDUFS6
T16 1281-1290 GeneOrGeneProduct denotes subunit a
T17 1291-1301 GeneOrGeneProduct denotes pseudogene
T18 1390-1396 GeneOrGeneProduct denotes NDUFS2
T19 1415-1439 GeneOrGeneProduct denotes conserved protein kinase
T20 1471-1477 GeneOrGeneProduct denotes NDUFS3
T21 1514-1530 GeneOrGeneProduct denotes casein kinase II

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 110-112 DiseaseOrPhenotypicFeature denotes IP 0010631
T2 147-149 DiseaseOrPhenotypicFeature denotes IP 0010631
T3 255-258 DiseaseOrPhenotypicFeature denotes can 0012833
T4 318-320 DiseaseOrPhenotypicFeature denotes IP 0010631
T5 348-350 DiseaseOrPhenotypicFeature denotes HP 0017853|0006249
T7 369-371 DiseaseOrPhenotypicFeature denotes IP 0010631
T8 589-591 DiseaseOrPhenotypicFeature denotes IP 0010631
T9 1143-1147 DiseaseOrPhenotypicFeature denotes gave 0006767

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 525-540 DiseaseOrPhenotypicFeature denotes remaining human D000071298
T2 1627-1656 DiseaseOrPhenotypicFeature denotes enzymatic complex I-deficient DISEASE

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 1627-1656 DiseaseOrPhenotypicFeature denotes enzymatic complex I-deficient DISEASE

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 88-108 ChemicalEntity denotes iron sulphur protein http://purl.obolibrary.org/obo/CHEBI_35135
T2 189-203 ChemicalEntity denotes oxidoreductase D010088
T3 278-290 ChemicalEntity denotes flavoprotein http://purl.obolibrary.org/obo/CHEBI_5086
T4 292-294 ChemicalEntity denotes FP http://purl.obolibrary.org/obo/CHEBI_5086
T5 297-316 ChemicalEntity denotes iron-sulfur protein http://purl.obolibrary.org/obo/CHEBI_35135
T6 557-571 ChemicalEntity denotes oxidoreductase D010088

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 66-71 OrganismTaxon denotes human
T2 141-146 OrganismTaxon denotes human
T3 535-540 OrganismTaxon denotes human
T4 905-911 OrganismTaxon denotes bovine
T5 1068-1073 OrganismTaxon denotes human
T6 1074-1080 OrganismTaxon denotes rodent
T7 1113-1118 OrganismTaxon denotes human
T8 1150-1155 OrganismTaxon denotes human
T9 1657-1665 OrganismTaxon denotes patients

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T6 557-571 ChemicalEntity denotes oxidoreductase D010088
T5 297-316 ChemicalEntity denotes iron-sulfur protein http://purl.obolibrary.org/obo/CHEBI_35135
T4 292-294 ChemicalEntity denotes FP http://purl.obolibrary.org/obo/CHEBI_5086
T3 278-290 ChemicalEntity denotes flavoprotein http://purl.obolibrary.org/obo/CHEBI_5086
T2 189-203 ChemicalEntity denotes oxidoreductase D010088
T1 88-108 ChemicalEntity denotes iron sulphur protein http://purl.obolibrary.org/obo/CHEBI_35135
T21 1514-1530 GeneOrGeneProduct denotes casein kinase II
T20 1471-1477 GeneOrGeneProduct denotes NDUFS3
T19 1415-1439 GeneOrGeneProduct denotes conserved protein kinase
T18 1390-1396 GeneOrGeneProduct denotes NDUFS2
T17 1291-1301 GeneOrGeneProduct denotes pseudogene
T16 1281-1290 GeneOrGeneProduct denotes subunit a
T15 1274-1280 GeneOrGeneProduct denotes NDUFS6
T14 1200-1206 GeneOrGeneProduct denotes NDUFS3
T13 1189-1195 GeneOrGeneProduct denotes NDUFS2
T12 652-658 GeneOrGeneProduct denotes 13 kDa
T11 644-650 GeneOrGeneProduct denotes NDUFS6
T10 631-637 GeneOrGeneProduct denotes 30 kDa
T9 623-629 GeneOrGeneProduct denotes NDUFS3
T8 606-612 GeneOrGeneProduct denotes NDUFS2
T7 541-571 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase
T80720 348-350 GeneOrGeneProduct denotes HP
T95800 327-346 GeneOrGeneProduct denotes hydrophobic protein
T42513 297-316 GeneOrGeneProduct denotes iron-sulfur protein
T27971 292-294 GeneOrGeneProduct denotes FP
T20220 278-290 GeneOrGeneProduct denotes flavoprotein
T3874 173-215 GeneOrGeneProduct denotes NADH:ubiquinone oxidoreductase (complex I)
T39827 1627-1656 DiseaseOrPhenotypicFeature denotes enzymatic complex I-deficient DISEASE
T75453 1657-1665 OrganismTaxon denotes patients
T95551 1150-1155 OrganismTaxon denotes human
T38438 1113-1118 OrganismTaxon denotes human
T56808 1074-1080 OrganismTaxon denotes rodent
T50539 1068-1073 OrganismTaxon denotes human
T82675 905-911 OrganismTaxon denotes bovine
T4741 535-540 OrganismTaxon denotes human
T82621 141-146 OrganismTaxon denotes human
T81163 66-71 OrganismTaxon denotes human