| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T2 |
35-56 |
CellComponent |
denotes |
endoplasmic reticulum |
| T3 |
64-71 |
Nucleus |
denotes |
nucleus |
| T4 |
102-133 |
Enzyme |
denotes |
protein kinase/endoribonuclease |
| T5 |
145-154 |
Eukaryote |
denotes |
mammalian |
| T6 |
155-160 |
Cell |
denotes |
cells |
| T7 |
162-172 |
Eukaryote |
denotes |
Eukaryotes |
| T9 |
209-216 |
Protein |
denotes |
protein |
| T10 |
224-245 |
CellComponent |
denotes |
endoplasmic reticulum |
| T11 |
247-249 |
CellComponent |
denotes |
ER |
| T15 |
289-294 |
Gene |
denotes |
genes |
| T18 |
335-338 |
Protein |
denotes |
BiP |
| T19 |
365-370 |
Eukaryote |
denotes |
human |
| T20 |
371-375 |
DNA |
denotes |
cDNA |
| T21 |
387-394 |
Protein |
denotes |
homolog |
| T22 |
398-422 |
Eukaryote |
denotes |
Saccharomyces cerevisiae |
| T23 |
423-428 |
Protein |
denotes |
Ire1p |
| T25 |
488-493 |
Eukaryote |
denotes |
yeast |
| T26 |
499-518 |
GeneProduct |
denotes |
gene product hIre1p |
| T27 |
524-552 |
Protein |
denotes |
type 1 transmembrane protein |
| T28 |
566-584 |
ProteinDomain |
denotes |
cytoplasmic domain |
| T29 |
617-622 |
Eukaryote |
denotes |
yeast |
| T30 |
623-634 |
Protein |
denotes |
counterpart |
| T32 |
680-686 |
ProteinDomain |
denotes |
domain |
| T33 |
701-708 |
Enzyme |
denotes |
RNase L |
| T34 |
723-737 |
ProteinDomain |
denotes |
luminal domain |
| T35 |
772-777 |
Eukaryote |
denotes |
yeast |
| T36 |
778-790 |
GeneProduct |
denotes |
gene product |
| T37 |
792-798 |
Protein |
denotes |
hIre1p |
| T43 |
945-950 |
Eukaryote |
denotes |
yeast |
| T44 |
951-955 |
Gene |
denotes |
HAC1 |
| T45 |
956-960 |
MessengerRNA |
denotes |
mRNA |
| T47 |
1011-1016 |
Eukaryote |
denotes |
yeast |
| T48 |
1017-1022 |
Protein |
denotes |
Ire1p |
| T50 |
1038-1044 |
Protein |
denotes |
hIre1p |
| T52 |
1066-1068 |
CellComponent |
denotes |
ER |
| T53 |
1110-1126 |
CellComponent |
denotes |
nuclear envelope |
| T54 |
1160-1180 |
CellComponent |
denotes |
nuclear pore complex |
| T56 |
1196-1206 |
MessengerRNA |
denotes |
Ire1p mRNA |
| T58 |
1270-1276 |
Protein |
denotes |
hIre1p |
| T60 |
1321-1337 |
Protein |
denotes |
wild-type hIre1p |
| T62 |
1365-1378 |
ReporterGene |
denotes |
reporter gene |
| T63 |
1416-1419 |
Eukaryote |
denotes |
rat |
| T64 |
1420-1423 |
Gene |
denotes |
BiP |
| T65 |
1424-1432 |
Promoter |
denotes |
promoter |
| T67 |
1481-1487 |
Protein |
denotes |
hIre1p |
| T71 |
1575-1578 |
Gene |
denotes |
BiP |
| T72 |
1579-1587 |
Promoter |
denotes |
promoter |
| T73 |
1603-1605 |
CellComponent |
denotes |
ER |
| T74 |
1606-1612 |
Stress |
denotes |
stress |
| T78 |
1693-1699 |
Protein |
denotes |
hIre1p |
| T79 |
1739-1755 |
Protein |
denotes |
unfolded protein |
| T81 |
1776-1785 |
Eukaryote |
denotes |
mammalian |
| T82 |
1786-1791 |
Cell |
denotes |
cells |
| T83 |
135-140 |
Protein |
denotes |
Ire1p |
| T13 |
304-325 |
Protein |
denotes |
ER protein chaperones |
| T14 |
644-673 |
ProteinDomain |
denotes |
Ser/Thr protein kinase domain |
| T16 |
822-827 |
Cell |
denotes |
cells |
| T31 |
868-876 |
CatalyticActivity |
denotes |
activity |
| T39 |
884-900 |
Enzyme |
denotes |
endoribonuclease |
| T40 |
901-909 |
CatalyticActivity |
denotes |
activity |
| T42 |
982-998 |
Enzyme |
denotes |
endoribonuclease |
| T46 |
999-1007 |
CatalyticActivity |
denotes |
activity |
| T84 |
964-973 |
Substrate |
denotes |
substrate |
| T85 |
1277-1283 |
Enzyme |
denotes |
kinase |
| T86 |
1284-1292 |
CatalyticActivity |
denotes |
activity |
| T70 |
812-821 |
Eukaryote |
denotes |
mammalian |
| E1 |
2-25 |
ResponseProcess |
denotes |
stress response pathway |
| E2 |
173-180 |
ResponseProcess |
denotes |
respond |
| E5 |
452-484 |
SignalingPathway |
denotes |
this signal transduction pathway |
| E6 |
799-808 |
GeneExpression |
denotes |
expressed |
| E7 |
1024-1037 |
PositiveRegulationOfGeneExpression |
denotes |
Overexpressed |
| E8 |
1049-1058 |
Localization |
denotes |
localized |
| E9 |
1182-1192 |
TranscriptionOfGene |
denotes |
Expression |
| E10 |
1211-1224 |
RegulatoryProcess |
denotes |
autoregulated |
| E11 |
1303-1317 |
PositiveRegulationOfGeneExpression |
denotes |
overexpression |
| E12 |
1353-1362 |
PositiveRegulation |
denotes |
activated |
| E13 |
1442-1452 |
GeneExpression |
denotes |
expression |
| E14 |
1533-1540 |
NegativeRegulation |
denotes |
prevent |
| E17 |
1613-1620 |
PositiveRegulation |
denotes |
induced |
| E18 |
1624-1634 |
NegativeRegulation |
denotes |
inhibition |
| E19 |
1638-1660 |
CellularMetabolicProcess |
denotes |
N-linked glycosylation |
| E20 |
1756-1772 |
ResponseProcess |
denotes |
response pathway |
| E3 |
254-285 |
PositiveRegulationOfTranscriptionOfGene |
denotes |
up-regulating the transcription |
| E4 |
848-867 |
Phosphorylation |
denotes |
autophosphorylation |
| E21 |
915-922 |
Cleavage |
denotes |
cleaved |
| E22 |
1385-1408 |
RegulationOfTranscription |
denotes |
transcriptional control |
| E15 |
1541-1567 |
PositiveRegulationOfTranscription |
denotes |
transcriptional activation |
| R1 |
E1 |
T2 |
locatedIn |
stress response pathway,endoplasmic reticulum |
| R2 |
E1 |
T3 |
locatedIn |
stress response pathway,nucleus |
| R3 |
T4 |
T6 |
locatedIn |
protein kinase/endoribonuclease,cells |
| R4 |
T6 |
T5 |
fromSpecies |
cells,mammalian |
| R5 |
E2 |
T7 |
locatedIn |
respond,Eukaryotes |
| R6 |
T9 |
T10 |
locatedIn |
protein,endoplasmic reticulum |
| R10 |
T20 |
T21 |
encodes |
cDNA,homolog |
| R11 |
T20 |
T19 |
fromSpecies |
cDNA,human |
| R12 |
T23 |
T22 |
fromSpecies |
Ire1p,Saccharomyces cerevisiae |
| R13 |
E5 |
T25 |
fromSpecies |
this signal transduction pathway,yeast |
| R14 |
T27 |
T28 |
hasPart |
type 1 transmembrane protein,cytoplasmic domain |
| R16 |
T30 |
T32 |
hasPart |
counterpart,domain |
| R17 |
T30 |
T29 |
fromSpecies |
counterpart,yeast |
| R18 |
T36 |
T35 |
fromSpecies |
gene product,yeast |
| R24 |
T44 |
T45 |
encodes |
HAC1,mRNA |
| R25 |
T44 |
T43 |
fromSpecies |
HAC1,yeast |
| R27 |
T48 |
T47 |
fromSpecies |
Ire1p,yeast |
| R28 |
E8 |
T52 |
locatedIn |
localized,ER |
| R29 |
T64 |
T63 |
fromSpecies |
BiP,rat |
| R30 |
T64 |
T65 |
hasPart |
BiP,promoter |
| R31 |
T71 |
T72 |
hasPart |
BiP,promoter |
| R32 |
T74 |
T73 |
locatedIn |
stress,ER |
| R33 |
E20 |
T82 |
locatedIn |
response pathway,cells |
| R34 |
T82 |
T81 |
fromSpecies |
cells,mammalian |
| R7 |
T15 |
T13 |
encodes |
genes,ER protein chaperones |
| R8 |
T30 |
T14 |
hasPart |
counterpart,Ser/Thr protein kinase domain |
| R9 |
E6 |
T16 |
locatedIn |
expressed,cells |
| R15 |
T37 |
T31 |
hasFunction |
hIre1p,activity |
| R19 |
T37 |
T40 |
hasFunction |
hIre1p,activity |
| R20 |
E8 |
T53 |
locatedIn |
localized,nuclear envelope |
| R21 |
E8 |
T54 |
locatedIn |
localized,nuclear pore complex |
| R22 |
T16 |
T70 |
fromSpecies |
cells,mammalian |
| R24 |
T37 |
E6 |
hasPatient |
hIre1p,expressed |
| R25 |
T50 |
E7 |
hasPatient |
hIre1p,Overexpressed |
| R26 |
T50 |
E8 |
hasPatient |
hIre1p,localized |
| R27 |
T56 |
E9 |
hasPatient |
Ire1p mRNA,Expression |
| R28 |
E9 |
E10 |
hasPatient |
Expression,autoregulated |
| R29 |
E11 |
E12 |
hasAgent |
overexpression,activated |
| R30 |
T62 |
E12 |
hasPatient |
reporter gene,activated |
| R31 |
T67 |
E13 |
hasPatient |
hIre1p,expression |
| R32 |
E13 |
E14 |
hasAgent |
expression,prevent |
| R33 |
E15 |
E14 |
hasPatient |
transcriptional activation,prevent |
| R34 |
E18 |
E17 |
hasAgent |
inhibition,induced |
| R35 |
T74 |
E17 |
hasPatient |
stress,induced |
| R36 |
E19 |
E18 |
hasPatient |
N-linked glycosylation,inhibition |
| R37 |
T79 |
E20 |
hasAgent |
unfolded protein,response pathway |
| R38 |
T15 |
E3 |
hasPatient |
genes,up-regulating the transcription |
| R39 |
T45 |
E21 |
hasPatient |
mRNA,cleaved |
| R40 |
T65 |
E22 |
hasPatient |
promoter,transcriptional control |
| R41 |
T72 |
E15 |
hasPatient |
promoter,transcriptional activation |
