PubMed:9585606 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/9585606","sourcedb":"PubMed","sourceid":"9585606","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/9585606","text":"The hemochromatosis 845 G--\u003eA and 187 C--\u003eG mutations: prevalence in non-Caucasian populations.\nHemochromatosis, the inherited disorder of iron metabolism, leads, if untreated, to progressive iron overload and premature death. The hemochromatosis gene, HFE, recently has been identified, and characterization of this gene has shown that it contains two mutations that result in amino acid substitutions-cDNA nucleotides 845 G--\u003eA (C282Y) and 187 C--\u003eG (H63D). Although hemochromatosis is common in Caucasians, affecting \u003e=1/300 individuals of northern European origin, it has not been recognized in other populations. The present study used PCR and restriction-enzyme digestion to analyze the frequency of the 845 G--\u003eA and 187 C--\u003eG mutations in HLA-typed samples from non-Caucasian populations, comprising Australian Aboriginal, Chinese, and Pacific Islanders. Results showed that the 845 G--\u003eA mutation was present in these populations (allele frequency 0.32%), and, furthermore, it was always seen in conjunction with HLA haplotypes common in Caucasians, suggesting that 845 G--\u003eA may have been introduced into these populations by Caucasian admixture. 187 C--\u003eG was present at an allele frequency of 2.68% in the two populations analyzed (Australian Aboriginal and Chinese). In the Australian Aboriginal samples, 187 C--\u003eG was found to be associated with HLA haplotypes common in Caucasians, suggesting that it was introduced by recent admixture. In the Chinese samples analyzed, 187 C--\u003eG was present in association with a wide variety of HLA haplotypes, showing this mutation to be widespread and likely to predate the more genetically restricted 845 G--\u003eA mutation.","tracks":[{"project":"NCBIDiseaseCorpus","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier:D006432"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease:D006432"},{"id":"T3","span":{"begin":117,"end":154},"obj":"DiseaseClass:D019189"},{"id":"T4","span":{"begin":192,"end":205},"obj":"SpecificDisease:D019190"},{"id":"T5","span":{"begin":210,"end":225},"obj":"SpecificDisease:D003643"},{"id":"T6","span":{"begin":231,"end":246},"obj":"Modifier:D006432"},{"id":"T7","span":{"begin":469,"end":484},"obj":"SpecificDisease:D006432"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T2","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T3","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T4","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T5","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T6","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T7","pred":"source","obj":"NCBIDiseaseCorpus"}]},{"project":"NCBI-Disease-Test","denotations":[{"id":"T605","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T606","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T607","span":{"begin":117,"end":154},"obj":"DiseaseClass"},{"id":"T608","span":{"begin":192,"end":205},"obj":"SpecificDisease"},{"id":"T609","span":{"begin":210,"end":225},"obj":"SpecificDisease"},{"id":"T610","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T611","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"id":"A605","pred":"database_id","subj":"T605","obj":"D006432"},{"id":"A606","pred":"database_id","subj":"T606","obj":"D006432"},{"id":"A607","pred":"database_id","subj":"T607","obj":"D019189"},{"id":"A608","pred":"database_id","subj":"T608","obj":"D019190"},{"id":"A609","pred":"database_id","subj":"T609","obj":"D003643"},{"id":"A610","pred":"database_id","subj":"T610","obj":"D006432"},{"id":"A611","pred":"database_id","subj":"T611","obj":"D006432"},{"subj":"T605","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T606","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T607","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T608","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T609","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T610","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T611","pred":"source","obj":"NCBI-Disease-Test"}]},{"project":"NCBI-Disease-Test-Assistant-Knowledge","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"}]},{"project":"NCBI-Disease-Test-4o-NoGuidelineInPrompt","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":127,"end":154},"obj":"DiseaseClass"},{"id":"T4","span":{"begin":180,"end":205},"obj":"CompositeMention"},{"id":"T5","span":{"begin":210,"end":225},"obj":"CompositeMention"},{"id":"T6","span":{"begin":231,"end":246},"obj":"SpecificDisease"},{"id":"T7","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T7","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"}]},{"project":"NCBI-Disease-Test-4o-GuidelineInPrompt","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"}]},{"project":"NCBI-Disease-Corpus-UpdatedGuideline","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":192,"end":205},"obj":"Modifier"},{"id":"T4","span":{"begin":231,"end":246},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"}]},{"project":"NCBI-Disease-Corpus-humanintheloop","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"}]},{"project":"NCBI-Disease-Corpus-rezarta1","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"}]},{"project":"NCBI-Disease-Corpus-All","denotations":[{"id":"T605","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T606","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T607","span":{"begin":117,"end":154},"obj":"DiseaseClass"},{"id":"T608","span":{"begin":192,"end":205},"obj":"SpecificDisease"},{"id":"T609","span":{"begin":210,"end":225},"obj":"SpecificDisease"},{"id":"T610","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T611","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"id":"A605","pred":"database_id","subj":"T605","obj":"D006432"},{"id":"A606","pred":"database_id","subj":"T606","obj":"D006432"},{"id":"A607","pred":"database_id","subj":"T607","obj":"D019189"},{"id":"A608","pred":"database_id","subj":"T608","obj":"D019190"},{"id":"A609","pred":"database_id","subj":"T609","obj":"D003643"},{"id":"A610","pred":"database_id","subj":"T610","obj":"D006432"},{"id":"A611","pred":"database_id","subj":"T611","obj":"D006432"},{"subj":"T605","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T606","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T607","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T608","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T609","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T610","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T611","pred":"source","obj":"NCBI-Disease-Corpus-All"}]},{"project":"NCBI-Disease-Corpus-2stage-All","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"}]},{"project":"NCBI-Disease-Corpus-rezarta-All","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"}]},{"project":"NCBI-Disease-Corpus-4oGuideline-All","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"}]},{"project":"NCBI-Disease-Corpus-Simple-All","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"}]},{"project":"NCBI-Disease-Corpus-o3-2","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"}]},{"project":"NCBI-Disease-Corpus-high-o3-1","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"}]},{"project":"NCBI-Disease-Corpus-high-o3-2","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"}]},{"project":"12345","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"12345"},{"subj":"T2","pred":"source","obj":"12345"},{"subj":"T3","pred":"source","obj":"12345"},{"subj":"T4","pred":"source","obj":"12345"}]},{"project":"123456","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T4","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"123456"},{"subj":"T2","pred":"source","obj":"123456"},{"subj":"T3","pred":"source","obj":"123456"},{"subj":"T4","pred":"source","obj":"123456"}]},{"project":"NCBI-Disease-Corpus-GPT5-withguidelines","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":127,"end":154},"obj":"DiseaseClass"},{"id":"T4","span":{"begin":192,"end":205},"obj":"DiseaseClass"},{"id":"T5","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T6","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"}]},{"project":"NCBI-Disease-Corpus-GPT5-noguidelines","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":117,"end":126},"obj":"Modifier"},{"id":"T4","span":{"begin":127,"end":154},"obj":"DiseaseClass"},{"id":"T5","span":{"begin":166,"end":175},"obj":"Modifier"},{"id":"T6","span":{"begin":180,"end":191},"obj":"Modifier"},{"id":"T7","span":{"begin":192,"end":205},"obj":"DiseaseClass"},{"id":"T8","span":{"begin":231,"end":246},"obj":"SpecificDisease"},{"id":"T9","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T7","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T8","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T9","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"}]},{"project":"NCBI-Disease-Corpus-GPT5-guidelineprompt","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":117,"end":154},"obj":"DiseaseClass"},{"id":"T4","span":{"begin":192,"end":205},"obj":"DiseaseClass"},{"id":"T5","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T6","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"}]},{"project":"NCBI-Disease-Corpus-Moderated1","denotations":[{"id":"T1","span":{"begin":4,"end":19},"obj":"Modifier"},{"id":"T2","span":{"begin":96,"end":111},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":117,"end":154},"obj":"DiseaseClass"},{"id":"T4","span":{"begin":231,"end":246},"obj":"Modifier"},{"id":"T5","span":{"begin":469,"end":484},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"NCBIDiseaseCorpus","color":"#93ecde","default":true},{"id":"NCBI-Disease-Test","color":"#ecc393"},{"id":"NCBI-Disease-Test-Assistant-Knowledge","color":"#a993ec"},{"id":"NCBI-Disease-Test-4o-NoGuidelineInPrompt","color":"#96ec93"},{"id":"NCBI-Disease-Test-4o-GuidelineInPrompt","color":"#ec93b0"},{"id":"NCBI-Disease-Corpus-UpdatedGuideline","color":"#93caec"},{"id":"NCBI-Disease-Corpus-humanintheloop","color":"#e4ec93"},{"id":"NCBI-Disease-Corpus-rezarta1","color":"#da93ec"},{"id":"NCBI-Disease-Corpus-All","color":"#93ecc0"},{"id":"NCBI-Disease-Corpus-2stage-All","color":"#eca693"},{"id":"NCBI-Disease-Corpus-rezarta-All","color":"#939aec"},{"id":"NCBI-Disease-Corpus-4oGuideline-All","color":"#b4ec93"},{"id":"NCBI-Disease-Corpus-Simple-All","color":"#ec93ce"},{"id":"NCBI-Disease-Corpus-o3-2","color":"#93e8ec"},{"id":"NCBI-Disease-Corpus-high-o3-1","color":"#ecd693"},{"id":"NCBI-Disease-Corpus-high-o3-2","color":"#bc93ec"},{"id":"12345","color":"#93eca2"},{"id":"123456","color":"#ec939d"},{"id":"NCBI-Disease-Corpus-GPT5-withguidelines","color":"#93b7ec"},{"id":"NCBI-Disease-Corpus-GPT5-noguidelines","color":"#d2ec93"},{"id":"NCBI-Disease-Corpus-GPT5-guidelineprompt","color":"#ec93ec"},{"id":"NCBI-Disease-Corpus-Moderated1","color":"#93ecd2"}]}]}}