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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-61 Sentence denotes Oxidants, transcription factors, and intestinal inflammation.
T2 62-206 Sentence denotes It is now well appreciated that chronic gut inflammation is characterized by enhanced production of reactive metabolites of oxygen and nitrogen.
T3 207-348 Sentence denotes Some of these oxidants are known to modulate the expression of a variety of genes that are involved in the immune and inflammatory responses.
T4 349-543 Sentence denotes For example, certain oxidants are known to activate the nuclear transcription factor kappa B, which regulates the expression of a variety of different adhesion molecules, cytokines, and enzymes.
T5 544-630 Sentence denotes Oxidants are also known to activate another transcription factor, activator protein-1.
T6 631-800 Sentence denotes This transcription factor is composed of products from the fos and jun proto-oncogene family and is believed to be important in regulating cell growth and proliferation.
T7 801-1003 Sentence denotes Finally, oxidants are believed to promote intestinal epithelial cell apoptosis, and the B-cell lymphoma/leukemia-2 gene product is believed to inhibit this phenomenon in an antioxidant-dependent manner.
T8 1004-1250 Sentence denotes Taken together, these observations suggest that nontoxic concentrations of reactive metabolites of oxygen and nitrogen play an important role in regulating the expression of genes involved in the inflammatory response and in modulating apoptosis.
T1 0-61 Sentence denotes Oxidants, transcription factors, and intestinal inflammation.
T2 62-206 Sentence denotes It is now well appreciated that chronic gut inflammation is characterized by enhanced production of reactive metabolites of oxygen and nitrogen.
T3 207-348 Sentence denotes Some of these oxidants are known to modulate the expression of a variety of genes that are involved in the immune and inflammatory responses.
T4 349-543 Sentence denotes For example, certain oxidants are known to activate the nuclear transcription factor kappa B, which regulates the expression of a variety of different adhesion molecules, cytokines, and enzymes.
T5 544-630 Sentence denotes Oxidants are also known to activate another transcription factor, activator protein-1.
T6 631-800 Sentence denotes This transcription factor is composed of products from the fos and jun proto-oncogene family and is believed to be important in regulating cell growth and proliferation.
T7 801-1003 Sentence denotes Finally, oxidants are believed to promote intestinal epithelial cell apoptosis, and the B-cell lymphoma/leukemia-2 gene product is believed to inhibit this phenomenon in an antioxidant-dependent manner.
T8 1004-1250 Sentence denotes Taken together, these observations suggest that nontoxic concentrations of reactive metabolites of oxygen and nitrogen play an important role in regulating the expression of genes involved in the inflammatory response and in modulating apoptosis.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 10-31 protein denotes transcription factors
T2 405-441 protein denotes nuclear transcription factor kappa B
T3 500-518 protein denotes adhesion molecules
T4 520-529 protein denotes cytokines
T5 535-542 protein denotes enzymes
T6 588-608 protein denotes transcription factor
T7 610-629 protein denotes activator protein-1
T8 636-656 protein denotes transcription factor
T9 690-723 protein denotes fos and jun proto-oncogene family
T10 843-869 cell_type denotes intestinal epithelial cell
T11 889-928 protein denotes B-cell lymphoma/leukemia-2 gene product

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-8 NP denotes Oxidants
C2 37-60 NP denotes intestinal inflammation
C3 94-118 NP denotes chronic gut inflammation
C4 162-205 NP denotes reactive metabolites of oxygen and nitrogen
C5 207-229 NP denotes Some of these oxidants
C7 270-288 NP denotes a variety of genes
C8 289-293 NP denotes that
C9 325-347 NP denotes inflammatory responses
C6 252-347 NP denotes the expression of a variety of genes that are involved in the immune and inflammatory responses
C10 401-441 NP denotes the nuclear transcription factor kappa B
C11 443-448 NP denotes which
C12 544-552 NP denotes Oxidants
C13 580-608 NP denotes another transcription factor
C14 610-629 NP denotes activator protein-1
C15 631-656 NP denotes This transcription factor
C16 810-818 NP denotes oxidants
C17 843-879 NP denotes intestinal epithelial cell apoptosis
C18 952-967 NP denotes this phenomenon
C19 1079-1122 NP denotes reactive metabolites of oxygen and nitrogen
C21 1196-1221 NP denotes the inflammatory response
C20 1160-1221 NP denotes the expression of genes involved in the inflammatory response
R1 C3 C2 coref-ident chronic gut inflammation,intestinal inflammation
R2 C4 C1 coref-ident reactive metabolites of oxygen and nitrogen,Oxidants
R3 C5 C4 coref-ident Some of these oxidants,reactive metabolites of oxygen and nitrogen
R4 C8 C7 coref-relat that,a variety of genes
R5 C11 C10 coref-relat which,the nuclear transcription factor kappa B
R6 C12 C4 coref-ident Oxidants,reactive metabolites of oxygen and nitrogen
R7 C14 C13 coref-appos activator protein-1,another transcription factor
R8 C15 C13 coref-ident This transcription factor,another transcription factor
R9 C16 C12 coref-ident oxidants,Oxidants
R10 C18 C17 coref-ident this phenomenon,intestinal epithelial cell apoptosis
R11 C19 C16 coref-ident reactive metabolites of oxygen and nitrogen,oxidants
R12 C21 C9 coref-ident the inflammatory response,inflammatory responses
R13 C20 C6 coref-ident the expression of genes involved in the inflammatory response,the expression of a variety of genes that are involved in the immune and inflammatory responses

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-61 Sentence denotes Oxidants, transcription factors, and intestinal inflammation.
S2 62-206 Sentence denotes It is now well appreciated that chronic gut inflammation is characterized by enhanced production of reactive metabolites of oxygen and nitrogen.
S3 207-348 Sentence denotes Some of these oxidants are known to modulate the expression of a variety of genes that are involved in the immune and inflammatory responses.
S4 349-543 Sentence denotes For example, certain oxidants are known to activate the nuclear transcription factor kappa B, which regulates the expression of a variety of different adhesion molecules, cytokines, and enzymes.
S5 544-630 Sentence denotes Oxidants are also known to activate another transcription factor, activator protein-1.
S6 631-800 Sentence denotes This transcription factor is composed of products from the fos and jun proto-oncogene family and is believed to be important in regulating cell growth and proliferation.
S7 801-1003 Sentence denotes Finally, oxidants are believed to promote intestinal epithelial cell apoptosis, and the B-cell lymphoma/leukemia-2 gene product is believed to inhibit this phenomenon in an antioxidant-dependent manner.
S8 1004-1250 Sentence denotes Taken together, these observations suggest that nontoxic concentrations of reactive metabolites of oxygen and nitrogen play an important role in regulating the expression of genes involved in the inflammatory response and in modulating apoptosis.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 10-31 protein_family_or_group denotes transcription factors
T2 37-60 other_name denotes intestinal inflammation
T3 94-118 other_name denotes chronic gut inflammation
T4 162-182 other_organic_compound denotes reactive metabolites
T5 186-192 atom denotes oxygen
T6 197-205 atom denotes nitrogen
T7 325-347 other_name denotes inflammatory responses
T8 405-412 protein_complex denotes nuclear
T9 413-433 protein_family_or_group denotes transcription factor
T10 500-518 protein_family_or_group denotes adhesion molecules
T11 520-529 protein_family_or_group denotes cytokines
T12 535-542 protein_family_or_group denotes enzymes
T13 588-608 protein_family_or_group denotes transcription factor
T14 610-629 protein_molecule denotes activator protein-1
T15 636-656 protein_family_or_group denotes transcription factor
T16 690-723 protein_family_or_group denotes fos and jun proto-oncogene family
T17 770-781 other_name denotes cell growth
T18 786-799 other_name denotes proliferation
T19 810-818 inorganic denotes oxidants
T20 843-869 cell_type denotes intestinal epithelial cell
T21 870-879 other_name denotes apoptosis
T22 889-928 protein_molecule denotes B-cell lymphoma/leukemia-2 gene product
T23 974-1002 other_name denotes antioxidant-dependent manner
T24 1052-1075 other_name denotes nontoxic concentrations
T25 1079-1099 other_organic_compound denotes reactive metabolites
T26 1103-1109 atom denotes oxygen
T27 1114-1122 atom denotes nitrogen
T28 1200-1221 other_name denotes inflammatory response
T29 1240-1249 other_name denotes apoptosis