PubMed:9443866 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/9443866","sourcedb":"PubMed","sourceid":"9443866","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/9443866","text":"Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations.\nTo facilitate the evaluation of ATM heterozygotes for susceptibility to other diseases, such as breast cancer, we have attempted to define the most common mutations and their frequencies in ataxia-telangiectasia (A-T) homozygotes from 10 ethnic populations. Both genomic mutations and their effects on cDNA were characterized. Protein-truncation testing of the entire ATM cDNA detected 92 (66%) truncating mutations in 140 mutant alleles screened. The haplotyping of patients with identical mutations indicates that almost all of these represent common ancestry and that very few spontaneously recurring ATM mutations exist. Assays requiring minimal amounts of genomic DNA were designed to allow rapid screening for common ethnic mutations. These rapid assays detected mutations in 76% of Costa Rican patients (3), 50% of Norwegian patients (1), 25% of Polish patients (4), and 14% of Italian patients (1), as well as in patients of Amish/Mennonite and Irish English backgrounds. Additional mutations were observed in Japanese, Utah Mormon, and African American patients. These assays should facilitate screening for A-T heterozygotes in the populations studied.","tracks":[{"project":"NCBIDiseaseCorpus","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease:D001260"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease:D001943"},{"id":"T3","span":{"begin":309,"end":330},"obj":"Modifier:D001260"},{"id":"T4","span":{"begin":332,"end":335},"obj":"Modifier:D001260"},{"id":"T5","span":{"begin":1236,"end":1239},"obj":"Modifier:D001260"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T2","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T3","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T4","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T5","pred":"source","obj":"NCBIDiseaseCorpus"}]},{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":151,"end":154},"obj":"gene:472"},{"id":"T1","span":{"begin":215,"end":228},"obj":"disease:C0006142"},{"id":"T2","span":{"begin":151,"end":154},"obj":"gene:472"},{"id":"T3","span":{"begin":215,"end":228},"obj":"disease:C0678222"},{"id":"T4","span":{"begin":151,"end":154},"obj":"gene:472"},{"id":"T5","span":{"begin":309,"end":330},"obj":"disease:C0004135"},{"id":"T6","span":{"begin":151,"end":154},"obj":"gene:472"},{"id":"T7","span":{"begin":332,"end":335},"obj":"disease:C0004135"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"},{"id":"R4","pred":"associated_with","subj":"T6","obj":"T7"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"},{"subj":"T2","pred":"source","obj":"DisGeNET"},{"subj":"T3","pred":"source","obj":"DisGeNET"},{"subj":"T4","pred":"source","obj":"DisGeNET"},{"subj":"T5","pred":"source","obj":"DisGeNET"},{"subj":"T6","pred":"source","obj":"DisGeNET"},{"subj":"T7","pred":"source","obj":"DisGeNET"}]},{"project":"DisGeNET5_gene_disease","denotations":[{"id":"9443866-1#32#35#gene472","span":{"begin":151,"end":154},"obj":"gene472"},{"id":"9443866-1#190#211#diseaseC0004135","span":{"begin":309,"end":330},"obj":"diseaseC0004135"},{"id":"9443866-1#213#216#diseaseC0004135","span":{"begin":332,"end":335},"obj":"diseaseC0004135"}],"relations":[{"id":"32#35#gene472190#211#diseaseC0004135","pred":"associated_with","subj":"9443866-1#32#35#gene472","obj":"9443866-1#190#211#diseaseC0004135"},{"id":"32#35#gene472213#216#diseaseC0004135","pred":"associated_with","subj":"9443866-1#32#35#gene472","obj":"9443866-1#213#216#diseaseC0004135"}],"attributes":[{"subj":"9443866-1#32#35#gene472","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"9443866-1#190#211#diseaseC0004135","pred":"source","obj":"DisGeNET5_gene_disease"},{"subj":"9443866-1#213#216#diseaseC0004135","pred":"source","obj":"DisGeNET5_gene_disease"}]},{"project":"NCBI-Disease-Test","denotations":[{"id":"T84","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T85","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T86","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T87","span":{"begin":332,"end":335},"obj":"Modifier"},{"id":"T88","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"id":"A84","pred":"database_id","subj":"T84","obj":"D001260"},{"id":"A85","pred":"database_id","subj":"T85","obj":"D001943"},{"id":"A86","pred":"database_id","subj":"T86","obj":"D001260"},{"id":"A87","pred":"database_id","subj":"T87","obj":"D001260"},{"id":"A88","pred":"database_id","subj":"T88","obj":"D001260"},{"subj":"T84","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T85","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T86","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T87","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T88","pred":"source","obj":"NCBI-Disease-Test"}]},{"project":"NCBI-Disease-Test-Assistant-Knowledge","denotations":[{"id":"T1","span":{"begin":87,"end":95},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":151,"end":168},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":309,"end":336},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":723,"end":736},"obj":"SpecificDisease"},{"id":"T6","span":{"begin":1236,"end":1253},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"}]},{"project":"NCBI-Disease-Test-4o-NoGuidelineInPrompt","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":336},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":1236,"end":1239},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"}]},{"project":"NCBI-Disease-Test-4o-GuidelineInPrompt","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"Modifier"},{"id":"T2","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"}]},{"project":"NCBI-Disease-Corpus-UpdatedGuideline","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":336},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"}]},{"project":"NCBI-Disease-Corpus-humanintheloop","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T3","span":{"begin":332,"end":335},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"}]},{"project":"NCBI-Disease-Corpus-rezarta1","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"}]},{"project":"NCBI-Disease-Corpus-All","denotations":[{"id":"T84","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T85","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T86","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T87","span":{"begin":332,"end":335},"obj":"Modifier"},{"id":"T88","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"id":"A84","pred":"database_id","subj":"T84","obj":"D001260"},{"id":"A85","pred":"database_id","subj":"T85","obj":"D001943"},{"id":"A86","pred":"database_id","subj":"T86","obj":"D001260"},{"id":"A87","pred":"database_id","subj":"T87","obj":"D001260"},{"id":"A88","pred":"database_id","subj":"T88","obj":"D001260"},{"subj":"T84","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T85","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T86","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T87","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T88","pred":"source","obj":"NCBI-Disease-Corpus-All"}]},{"project":"NCBI-Disease-Corpus-2stage-All","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T3","span":{"begin":332,"end":335},"obj":"Modifier"},{"id":"T4","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"}]},{"project":"NCBI-Disease-Corpus-rezarta-All","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"}]},{"project":"NCBI-Disease-Corpus-4oGuideline-All","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"Modifier"},{"id":"T2","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":332,"end":335},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":1236,"end":1239},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"}]},{"project":"NCBI-Disease-Corpus-Simple-All","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":87,"end":90},"obj":"Modifier"},{"id":"T3","span":{"begin":151,"end":154},"obj":"Modifier"},{"id":"T4","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":309,"end":336},"obj":"SpecificDisease"},{"id":"T6","span":{"begin":487,"end":490},"obj":"Modifier"},{"id":"T7","span":{"begin":723,"end":726},"obj":"Modifier"},{"id":"T8","span":{"begin":908,"end":919},"obj":"Modifier"},{"id":"T9","span":{"begin":941,"end":950},"obj":"Modifier"},{"id":"T10","span":{"begin":972,"end":978},"obj":"Modifier"},{"id":"T11","span":{"begin":1004,"end":1011},"obj":"Modifier"},{"id":"T12","span":{"begin":1052,"end":1067},"obj":"Modifier"},{"id":"T13","span":{"begin":1072,"end":1085},"obj":"Modifier"},{"id":"T14","span":{"begin":1137,"end":1145},"obj":"Modifier"},{"id":"T15","span":{"begin":1147,"end":1158},"obj":"Modifier"},{"id":"T16","span":{"begin":1164,"end":1180},"obj":"Modifier"},{"id":"T17","span":{"begin":1236,"end":1239},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T7","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T8","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T9","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T10","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T11","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T12","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T13","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T14","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T15","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T16","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T17","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"}]},{"project":"NCBI-Disease-Corpus-o3-2","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":332,"end":335},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":1236,"end":1239},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"}]},{"project":"NCBI-Disease-Corpus-high-o3-1","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":332,"end":335},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":1236,"end":1239},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"}]},{"project":"NCBI-Disease-Corpus-high-o3-2","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":332,"end":335},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"}]},{"project":"12345","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":309,"end":330},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":332,"end":335},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"12345"},{"subj":"T2","pred":"source","obj":"12345"},{"subj":"T3","pred":"source","obj":"12345"},{"subj":"T4","pred":"source","obj":"12345"}]},{"project":"123456","denotations":[{"id":"T1","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T3","span":{"begin":332,"end":335},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"123456"},{"subj":"T2","pred":"source","obj":"123456"},{"subj":"T3","pred":"source","obj":"123456"},{"subj":"T4","pred":"source","obj":"123456"}]},{"project":"NCBI-Disease-Corpus-GPT5-withguidelines","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T4","span":{"begin":332,"end":335},"obj":"Modifier"},{"id":"T5","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"}]},{"project":"NCBI-Disease-Corpus-GPT5-noguidelines","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":191,"end":205},"obj":"DiseaseClass"},{"id":"T3","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":309,"end":336},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":1236,"end":1239},"obj":"SpecificDisease"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"}]},{"project":"NCBI-Disease-Corpus-GPT5-guidelineprompt","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T4","span":{"begin":332,"end":335},"obj":"Modifier"},{"id":"T5","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"}]},{"project":"NCBI-Disease-Corpus-Moderated1","denotations":[{"id":"T1","span":{"begin":0,"end":21},"obj":"SpecificDisease"},{"id":"T2","span":{"begin":215,"end":228},"obj":"SpecificDisease"},{"id":"T3","span":{"begin":309,"end":330},"obj":"Modifier"},{"id":"T4","span":{"begin":332,"end":335},"obj":"Modifier"},{"id":"T5","span":{"begin":1236,"end":1239},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"NCBIDiseaseCorpus","color":"#c2ec93","default":true},{"id":"DisGeNET","color":"#ec93dd"},{"id":"DisGeNET5_gene_disease","color":"#93ece1"},{"id":"NCBI-Disease-Test","color":"#ecc793"},{"id":"NCBI-Disease-Test-Assistant-Knowledge","color":"#ad93ec"},{"id":"NCBI-Disease-Test-4o-NoGuidelineInPrompt","color":"#93ec93"},{"id":"NCBI-Disease-Test-4o-GuidelineInPrompt","color":"#ec93ac"},{"id":"NCBI-Disease-Corpus-UpdatedGuideline","color":"#93c6ec"},{"id":"NCBI-Disease-Corpus-humanintheloop","color":"#e0ec93"},{"id":"NCBI-Disease-Corpus-rezarta1","color":"#dd93ec"},{"id":"NCBI-Disease-Corpus-All","color":"#93ecc3"},{"id":"NCBI-Disease-Corpus-2stage-All","color":"#eca993"},{"id":"NCBI-Disease-Corpus-rezarta-All","color":"#9396ec"},{"id":"NCBI-Disease-Corpus-4oGuideline-All","color":"#b0ec93"},{"id":"NCBI-Disease-Corpus-Simple-All","color":"#ec93ca"},{"id":"NCBI-Disease-Corpus-o3-2","color":"#93e4ec"},{"id":"NCBI-Disease-Corpus-high-o3-1","color":"#ecda93"},{"id":"NCBI-Disease-Corpus-high-o3-2","color":"#c093ec"},{"id":"12345","color":"#93eca6"},{"id":"123456","color":"#ec939a"},{"id":"NCBI-Disease-Corpus-GPT5-withguidelines","color":"#93b4ec"},{"id":"NCBI-Disease-Corpus-GPT5-noguidelines","color":"#ceec93"},{"id":"NCBI-Disease-Corpus-GPT5-guidelineprompt","color":"#ec93e8"},{"id":"NCBI-Disease-Corpus-Moderated1","color":"#93ecd6"}]}]}}