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PubMed:9417100 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 23-32 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T3 55-62 Glycan_Motif denotes glucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG
T4 1234-1243 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE

sentences

Id Subject Object Predicate Lexical cue
T1 0-133 Sentence denotes Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase catalyzing the formation of type 1 chains.
T2 134-346 Sentence denotes Biochemical evidence suggests that the galactosyltransferase activity synthesizing type 1 carbohydrate chains is separate from the well characterized enzyme that is responsible for the synthesis of type 2 chains.
T3 347-532 Sentence denotes This was recently confirmed by the cloning, from melanoma cells, of an enzyme capable of synthesizing type 1 chains, which was shown to have no homology to other galactosyltransferases.
T4 533-676 Sentence denotes We report here the molecular cloning and functional expression of a second human beta3-galactosyltransferase distinct from the melanoma enzyme.
T5 677-861 Sentence denotes The new beta3-galactosyltransferase has homology to the melanoma enzyme in the putative catalytic domain, but has longer cytoplasmic and stem regions and a carboxyl-terminal extension.
T6 862-942 Sentence denotes Northern blots showed that the new gene is present primarily in brain and heart.
T7 943-1097 Sentence denotes When transfected into mammalian cells, this gene directs the synthesis of type 1 chains as determined by a monoclonal antibody specific for sialyl Lewisa.
T8 1098-1180 Sentence denotes A soluble version of the cloned enzyme was expressed in insect cells and purified.
T9 1181-1281 Sentence denotes The soluble enzyme readily catalyzes the transfer of galactose to GlcNAc to form Gal(beta1-3)GlcNAc.
T10 1282-1396 Sentence denotes It also has a minor but distinct transfer activity toward Gal, LacNAc, and lactose, but is inactive toward GalNAc.
T1 0-133 Sentence denotes Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase catalyzing the formation of type 1 chains.
T2 134-346 Sentence denotes Biochemical evidence suggests that the galactosyltransferase activity synthesizing type 1 carbohydrate chains is separate from the well characterized enzyme that is responsible for the synthesis of type 2 chains.
T3 347-532 Sentence denotes This was recently confirmed by the cloning, from melanoma cells, of an enzyme capable of synthesizing type 1 chains, which was shown to have no homology to other galactosyltransferases.
T4 533-676 Sentence denotes We report here the molecular cloning and functional expression of a second human beta3-galactosyltransferase distinct from the melanoma enzyme.
T5 677-861 Sentence denotes The new beta3-galactosyltransferase has homology to the melanoma enzyme in the putative catalytic domain, but has longer cytoplasmic and stem regions and a carboxyl-terminal extension.
T6 862-942 Sentence denotes Northern blots showed that the new gene is present primarily in brain and heart.
T7 943-1097 Sentence denotes When transfected into mammalian cells, this gene directs the synthesis of type 1 chains as determined by a monoclonal antibody specific for sialyl Lewisa.
T8 1098-1180 Sentence denotes A soluble version of the cloned enzyme was expressed in insect cells and purified.
T9 1181-1281 Sentence denotes The soluble enzyme readily catalyzes the transfer of galactose to GlcNAc to form Gal(beta1-3)GlcNAc.
T10 1282-1396 Sentence denotes It also has a minor but distinct transfer activity toward Gal, LacNAc, and lactose, but is inactive toward GalNAc.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 23-32 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T2 23-32 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T3 55-62 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose
T4 1234-1243 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T5 1234-1243 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 814-818 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T2 926-931 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T3 936-941 http://purl.obolibrary.org/obo/MAT_0000036 denotes heart

glycogenes

Id Subject Object Predicate Lexical cue
PD-GlycoGenes20190927-B_T1 713-716 https://acgg.asia/db/ggdb/info/gg135 denotes has
PD-GlycoGenes20190927-B_T2 787-790 https://acgg.asia/db/ggdb/info/gg135 denotes has
PD-GlycoGenes20190927-B_T3 1290-1293 https://acgg.asia/db/ggdb/info/gg135 denotes has

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 1247-1253 chem:24139 denotes GlcNAc
PD-NGLY1-deficiency-B_T2 1274-1280 chem:24139 denotes GlcNAc
T1 1247-1253 chem:24139 denotes GlcNAc
T2 1274-1280 chem:24139 denotes GlcNAc

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 396-404 Disease denotes melanoma http://purl.obolibrary.org/obo/MONDO_0005105
T2 660-668 Disease denotes melanoma http://purl.obolibrary.org/obo/MONDO_0005105
T3 733-741 Disease denotes melanoma http://purl.obolibrary.org/obo/MONDO_0005105

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 814-818 Body_part denotes stem http://purl.obolibrary.org/obo/MAT_0000239
T2 926-931 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 936-941 Body_part denotes heart http://purl.obolibrary.org/obo/MAT_0000036

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1345-1351 Glycan denotes LacNAc
T2 1357-1364 Glycan denotes lactose
T3 1389-1395 Glycan denotes GalNAc

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1345-1351 Glycan denotes LacNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G66213AR
T2 1357-1364 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T3 1389-1395 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 396-404 Phenotype denotes melanoma HP:0002861
T2 660-668 Phenotype denotes melanoma HP:0002861
T3 733-741 Phenotype denotes melanoma HP:0002861

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 13-18 OrganismTaxon denotes human 9606
T2 608-613 OrganismTaxon denotes human 9606
T3 965-974 OrganismTaxon denotes mammalian 40674

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 798-809 Body_part denotes cytoplasmic http://purl.obolibrary.org/obo/GO_0005737
T2 851-860 Body_part denotes extension http://purl.obolibrary.org/obo/UBERON_2000106
T3 926-931 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T5 936-941 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948|http://purl.obolibrary.org/obo/UBERON_0007100|http://purl.obolibrary.org/obo/UBERON_0015228|http://purl.obolibrary.org/obo/UBERON_0015230

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 396-404 Disease denotes melanoma MONDO:0005105
T2 660-668 Disease denotes melanoma MONDO:0005105
T3 733-741 Disease denotes melanoma MONDO:0005105

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-133 Sentence denotes Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase catalyzing the formation of type 1 chains.
T2 134-346 Sentence denotes Biochemical evidence suggests that the galactosyltransferase activity synthesizing type 1 carbohydrate chains is separate from the well characterized enzyme that is responsible for the synthesis of type 2 chains.
T3 347-532 Sentence denotes This was recently confirmed by the cloning, from melanoma cells, of an enzyme capable of synthesizing type 1 chains, which was shown to have no homology to other galactosyltransferases.
T4 533-676 Sentence denotes We report here the molecular cloning and functional expression of a second human beta3-galactosyltransferase distinct from the melanoma enzyme.
T5 677-861 Sentence denotes The new beta3-galactosyltransferase has homology to the melanoma enzyme in the putative catalytic domain, but has longer cytoplasmic and stem regions and a carboxyl-terminal extension.
T6 862-942 Sentence denotes Northern blots showed that the new gene is present primarily in brain and heart.
T7 943-1180 Sentence denotes When transfected into mammalian cells, this gene directs the synthesis of type 1 chains as determined by a monoclonal antibody specific for sialyl Lewisa. A soluble version of the cloned enzyme was expressed in insect cells and purified.
T8 1181-1281 Sentence denotes The soluble enzyme readily catalyzes the transfer of galactose to GlcNAc to form Gal(beta1-3)GlcNAc.
T9 1282-1396 Sentence denotes It also has a minor but distinct transfer activity toward Gal, LacNAc, and lactose, but is inactive toward GalNAc.

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 798-809 Body_part denotes cytoplasmic FMA:66835
T2 926-931 Body_part denotes brain FMA:50801
T3 936-941 Body_part denotes heart FMA:7088

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 814-818 Body_part denotes stem http://purl.obolibrary.org/obo/MAT_0000239
T2 926-931 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 936-941 Body_part denotes heart http://purl.obolibrary.org/obo/MAT_0000036

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 13-18 OrganismTaxon denotes human 9606
T2 608-613 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 798-809 Body_part denotes cytoplasmic http://purl.obolibrary.org/obo/GO_0005737
T2 851-860 Body_part denotes extension http://purl.obolibrary.org/obo/UBERON_2000106
T3 926-931 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T5 936-941 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948|http://purl.obolibrary.org/obo/UBERON_0007100|http://purl.obolibrary.org/obo/UBERON_0015228|http://purl.obolibrary.org/obo/UBERON_0015230

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 396-404 Phenotype denotes melanoma HP:0002861
T2 660-668 Phenotype denotes melanoma HP:0002861
T3 733-741 Phenotype denotes melanoma HP:0002861