PubMed:9398087
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 317-329 | Cell | denotes | granulocytic | http://purl.obolibrary.org/obo/CL:0000094 |
| T2 | 810-823 | Cell | denotes | promyelocytic | http://purl.obolibrary.org/obo/CL:0000836 |
| T3 | 1254-1267 | Cell | denotes | promyelocytic | http://purl.obolibrary.org/obo/CL:0000836 |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 97-125 | cell_type | denotes | human myeloid leukemia cells |
| T2 | 252-280 | cell_type | denotes | human myeloid leukemia cells |
| T3 | 349-360 | cell_line | denotes | HL-60 cells |
| T4 | 563-582 | cell_line | denotes | HL-60 and NB4 cells |
| T5 | 769-783 | cell_type | denotes | leukemia cells |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-157 | Sentence | denotes | Differanisole A, a novel antitumor antibiotic, enhances growth inhibition and differentiation of human myeloid leukemia cells induced by 9-cis retinoic acid. |
| S2 | 158-281 | Sentence | denotes | Differanisole A, 3,5-dichloro-2-hydroxy-4-methoxy-6-n-propylbenzoic acid, inhibited growth of human myeloid leukemia cells. |
| S3 | 282-418 | Sentence | denotes | The compound induced G1 arrest and granulocytic differentiation of HL-60 cells, although the differentiation-inducing effect was modest. |
| S4 | 419-716 | Sentence | denotes | Differanisole A and 9-cis retinoic acid (9cisRA) synergistically inhibited the growth and induced functional and morphologic differentiation of HL-60 and NB4 cells, whereas the combined treatment with differanisole A and all-trans retinoic acid or 1alpha,25-dihydroxyvitamin D3 was less effective. |
| S5 | 717-833 | Sentence | denotes | Similar results were obtained in primary culture of leukemia cells from a patient with acute promyelocytic leukemia. |
| S6 | 834-975 | Sentence | denotes | The synergistic effect on growth inhibition and induction of differentiation required simultaneous treatment with differanisole A and 9cisRA. |
| S7 | 976-1167 | Sentence | denotes | Differanisole A and an RXR-specific ligand (Ro47-5944) cooperatively inhibited the cell growth, while the combined effect of differanisole A and an RAR-specific ligand Am80 was just additive. |
| S8 | 1168-1286 | Sentence | denotes | Differanisole A in combination with 9cisRA may have implications for therapy of acute promyelocytic leukemia patients. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-15 | NP | denotes | Differanisole A |
| C2 | 17-45 | NP | denotes | a novel antitumor antibiotic |
| C3 | 97-125 | NP | denotes | human myeloid leukemia cells |
| C4 | 137-156 | NP | denotes | 9-cis retinoic acid |
| C5 | 158-173 | NP | denotes | Differanisole A |
| C6 | 175-230 | NP | denotes | 3,5-dichloro-2-hydroxy-4-methoxy-6-n-propylbenzoic acid |
| C7 | 252-280 | NP | denotes | human myeloid leukemia cells |
| C9 | 419-434 | NP | denotes | Differanisole A |
| C10 | 439-467 | NP | denotes | 9-cis retinoic acid (9cisRA) |
| C8 | 419-467 | NP | denotes | Differanisole A and 9-cis retinoic acid (9cisRA) |
| C11 | 620-635 | NP | denotes | differanisole A |
| C12 | 789-832 | NP | denotes | a patient with acute promyelocytic leukemia |
| C14 | 948-963 | NP | denotes | differanisole A |
| C15 | 968-974 | NP | denotes | 9cisRA |
| C13 | 948-974 | NP | denotes | differanisole A and 9cisRA |
| C16 | 976-991 | NP | denotes | Differanisole A |
| C17 | 1101-1116 | NP | denotes | differanisole A |
| C18 | 1168-1183 | NP | denotes | Differanisole A |
| C19 | 1204-1210 | NP | denotes | 9cisRA |
| C20 | 1248-1285 | NP | denotes | acute promyelocytic leukemia patients |
| R1 | C2 | C1 | coref-appos | a novel antitumor antibiotic,Differanisole A |
| R2 | C5 | C1 | coref-ident | Differanisole A,Differanisole A |
| R3 | C6 | C5 | coref-appos | "3,5-dichloro-2-hydroxy-4-methoxy-6-n-propylbenzoic acid",Differanisole A |
| R4 | C7 | C3 | coref-ident | human myeloid leukemia cells,human myeloid leukemia cells |
| R5 | C9 | C5 | coref-ident | Differanisole A,Differanisole A |
| R6 | C10 | C4 | coref-ident | 9-cis retinoic acid (9cisRA),9-cis retinoic acid |
| R7 | C11 | C9 | coref-ident | differanisole A,Differanisole A |
| R8 | C14 | C11 | coref-ident | differanisole A,differanisole A |
| R9 | C15 | C10 | coref-ident | 9cisRA,9-cis retinoic acid (9cisRA) |
| R10 | C13 | C8 | coref-ident | differanisole A and 9cisRA,Differanisole A and 9-cis retinoic acid (9cisRA) |
| R11 | C16 | C14 | coref-ident | Differanisole A,differanisole A |
| R12 | C17 | C16 | coref-ident | differanisole A,Differanisole A |
| R13 | C18 | C17 | coref-ident | Differanisole A,differanisole A |
| R14 | C19 | C15 | coref-ident | 9cisRA,9cisRA |
| R15 | C20 | C12 | coref-ident | acute promyelocytic leukemia patients,a patient with acute promyelocytic leukemia |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-15 | other_organic_compound | denotes | Differanisole A |
| T2 | 25-45 | other_organic_compound | denotes | antitumor antibiotic |
| T3 | 97-125 | cell_type | denotes | human myeloid leukemia cells |
| T4 | 137-156 | other_organic_compound | denotes | 9-cis retinoic acid |
| T5 | 158-173 | other_organic_compound | denotes | Differanisole A |
| T6 | 175-230 | other_organic_compound | denotes | 3,5-dichloro-2-hydroxy-4-methoxy-6-n-propylbenzoic acid |
| T7 | 252-280 | cell_type | denotes | human myeloid leukemia cells |
| T8 | 303-312 | other_name | denotes | G1 arrest |
| T9 | 317-345 | other_name | denotes | granulocytic differentiation |
| T10 | 349-360 | cell_line | denotes | HL-60 cells |
| T11 | 419-434 | other_organic_compound | denotes | Differanisole A |
| T12 | 439-458 | other_organic_compound | denotes | 9-cis retinoic acid |
| T13 | 460-466 | other_organic_compound | denotes | 9cisRA |
| T14 | 620-635 | other_organic_compound | denotes | differanisole A |
| T15 | 640-663 | other_organic_compound | denotes | all-trans retinoic acid |
| T16 | 667-696 | other_organic_compound | denotes | 1alpha,25-dihydroxyvitamin D3 |
| T17 | 769-783 | cell_type | denotes | leukemia cells |
| T18 | 804-832 | other_name | denotes | acute promyelocytic leukemia |
| T19 | 948-963 | other_organic_compound | denotes | differanisole A |
| T20 | 968-974 | other_organic_compound | denotes | 9cisRA |
| T21 | 976-991 | other_organic_compound | denotes | Differanisole A |
| T22 | 999-1018 | other_organic_compound | denotes | RXR-specific ligand |
| T23 | 1020-1029 | other_organic_compound | denotes | Ro47-5944 |
| T24 | 1101-1116 | other_organic_compound | denotes | differanisole A |
| T25 | 1124-1143 | other_organic_compound | denotes | RAR-specific ligand |
| T26 | 1144-1148 | other_organic_compound | denotes | Am80 |
| T27 | 1168-1183 | other_organic_compound | denotes | Differanisole A |
| T28 | 1204-1210 | other_organic_compound | denotes | 9cisRA |
| T29 | 1248-1276 | other_name | denotes | acute promyelocytic leukemia |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 103-119 | Phenotype | denotes | myeloid leukemia | HP:0012324 |
| T2 | 258-274 | Phenotype | denotes | myeloid leukemia | HP:0012324 |
| T3 | 769-777 | Phenotype | denotes | leukemia | HP:0001909 |
| T4 | 804-832 | Phenotype | denotes | acute promyelocytic leukemia | HP:0004836 |
| T5 | 1248-1276 | Phenotype | denotes | acute promyelocytic leukemia | HP:0004836 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 103-119 | Disease | denotes | myeloid leukemia | http://purl.obolibrary.org/obo/MONDO_0004643 |
| T2 | 258-274 | Disease | denotes | myeloid leukemia | http://purl.obolibrary.org/obo/MONDO_0004643 |
| T3 | 769-777 | Disease | denotes | leukemia | http://purl.obolibrary.org/obo/MONDO_0005059 |
| T4 | 804-832 | Disease | denotes | acute promyelocytic leukemia | http://purl.obolibrary.org/obo/MONDO_0012883 |
| T5 | 1248-1276 | Disease | denotes | acute promyelocytic leukemia | http://purl.obolibrary.org/obo/MONDO_0012883 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 97-102 | OrganismTaxon | denotes | human | 9606 |
| T2 | 252-257 | OrganismTaxon | denotes | human | 9606 |
| T3 | 791-798 | OrganismTaxon | denotes | patient | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 317-329 | Body_part | denotes | granulocytic | http://purl.obolibrary.org/obo/CL_0000094 |