PubMed:9391879 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/9391879","sourcedb":"PubMed","sourceid":"9391879","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/9391879","text":"Low frequency of BRCA1 germline mutations in 45 German breast/ovarian cancer families.\nIn this study we investigated 45 German breast/ovarian cancer families for germline mutations in the BRCA1 gene. We identified four germline mutations in three breast cancer families and in one breast-ovarian cancer family. among these were one frameshift mutation, one nonsense mutation, one novel splice site mutation, and one missense mutation. The missense mutation was also found in 2.8% of the general population, suggesting that it is not disease associated. The average age of disease onset in those families harbouring causative mutations was between 32.3 and 37.4 years, whereas the family harbouring the missense mutation had an average age of onset of 51.2 years. These findings show that BRCA1 is implicated in a small fraction of breast/ovarian cancer families suggesting the involvement of another susceptibility gene(s).","tracks":[{"project":"NCBIDiseaseCorpus","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"Modifier:D061325"},{"id":"T2","span":{"begin":127,"end":148},"obj":"Modifier:D061325"},{"id":"T3","span":{"begin":247,"end":260},"obj":"Modifier:D001943"},{"id":"T4","span":{"begin":281,"end":302},"obj":"Modifier:D061325"},{"id":"T5","span":{"begin":831,"end":852},"obj":"Modifier:D061325"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T2","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T3","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T4","pred":"source","obj":"NCBIDiseaseCorpus"},{"subj":"T5","pred":"source","obj":"NCBIDiseaseCorpus"}]},{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":788,"end":793},"obj":"gene:672"},{"id":"T1","span":{"begin":838,"end":852},"obj":"disease:C0029925"},{"id":"T2","span":{"begin":788,"end":793},"obj":"gene:672"},{"id":"T3","span":{"begin":838,"end":852},"obj":"disease:C1140680"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"attributes":[{"subj":"T0","pred":"source","obj":"DisGeNET"},{"subj":"T1","pred":"source","obj":"DisGeNET"},{"subj":"T2","pred":"source","obj":"DisGeNET"},{"subj":"T3","pred":"source","obj":"DisGeNET"}]},{"project":"NCBI-Disease-Test","denotations":[{"id":"T140","span":{"begin":55,"end":76},"obj":"Modifier"},{"id":"T141","span":{"begin":127,"end":148},"obj":"Modifier"},{"id":"T142","span":{"begin":247,"end":260},"obj":"Modifier"},{"id":"T143","span":{"begin":281,"end":302},"obj":"Modifier"},{"id":"T144","span":{"begin":831,"end":852},"obj":"Modifier"}],"attributes":[{"id":"A140","pred":"database_id","subj":"T140","obj":"D061325"},{"id":"A141","pred":"database_id","subj":"T141","obj":"D061325"},{"id":"A142","pred":"database_id","subj":"T142","obj":"D001943"},{"id":"A143","pred":"database_id","subj":"T143","obj":"D061325"},{"id":"A144","pred":"database_id","subj":"T144","obj":"D061325"},{"subj":"T140","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T141","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T142","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T143","pred":"source","obj":"NCBI-Disease-Test"},{"subj":"T144","pred":"source","obj":"NCBI-Disease-Test"}]},{"project":"NCBI-Disease-Test-Assistant-Knowledge","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Test-Assistant-Knowledge"}]},{"project":"NCBI-Disease-Test-4o-NoGuidelineInPrompt","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":533,"end":551},"obj":"Modifier"},{"id":"T6","span":{"begin":572,"end":585},"obj":"Modifier"},{"id":"T7","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"},{"subj":"T7","pred":"source","obj":"NCBI-Disease-Test-4o-NoGuidelineInPrompt"}]},{"project":"NCBI-Disease-Test-4o-GuidelineInPrompt","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"Modifier"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Test-4o-GuidelineInPrompt"}]},{"project":"NCBI-Disease-Corpus-UpdatedGuideline","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-UpdatedGuideline"}]},{"project":"NCBI-Disease-Corpus-humanintheloop","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-humanintheloop"}]},{"project":"NCBI-Disease-Corpus-rezarta1","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-rezarta1"}]},{"project":"NCBI-Disease-Corpus-All","denotations":[{"id":"T140","span":{"begin":55,"end":76},"obj":"Modifier"},{"id":"T141","span":{"begin":127,"end":148},"obj":"Modifier"},{"id":"T142","span":{"begin":247,"end":260},"obj":"Modifier"},{"id":"T143","span":{"begin":281,"end":302},"obj":"Modifier"},{"id":"T144","span":{"begin":831,"end":852},"obj":"Modifier"}],"attributes":[{"id":"A140","pred":"database_id","subj":"T140","obj":"D061325"},{"id":"A141","pred":"database_id","subj":"T141","obj":"D061325"},{"id":"A142","pred":"database_id","subj":"T142","obj":"D001943"},{"id":"A143","pred":"database_id","subj":"T143","obj":"D061325"},{"id":"A144","pred":"database_id","subj":"T144","obj":"D061325"},{"subj":"T140","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T141","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T142","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T143","pred":"source","obj":"NCBI-Disease-Corpus-All"},{"subj":"T144","pred":"source","obj":"NCBI-Disease-Corpus-All"}]},{"project":"NCBI-Disease-Corpus-2stage-All","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-2stage-All"}]},{"project":"NCBI-Disease-Corpus-rezarta-All","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-rezarta-All"}]},{"project":"NCBI-Disease-Corpus-4oGuideline-All","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-4oGuideline-All"}]},{"project":"NCBI-Disease-Corpus-Simple-All","denotations":[{"id":"T1","span":{"begin":17,"end":85},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":157},"obj":"CompositeMention"},{"id":"T3","span":{"begin":188,"end":198},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T5","span":{"begin":281,"end":309},"obj":"CompositeMention"},{"id":"T6","span":{"begin":533,"end":540},"obj":"Modifier"},{"id":"T7","span":{"begin":572,"end":579},"obj":"Modifier"},{"id":"T8","span":{"begin":831,"end":861},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T6","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T7","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"},{"subj":"T8","pred":"source","obj":"NCBI-Disease-Corpus-Simple-All"}]},{"project":"NCBI-Disease-Corpus-o3-2","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"Modifier"},{"id":"T2","span":{"begin":127,"end":148},"obj":"Modifier"},{"id":"T3","span":{"begin":247,"end":260},"obj":"Modifier"},{"id":"T4","span":{"begin":281,"end":302},"obj":"Modifier"},{"id":"T5","span":{"begin":831,"end":852},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-o3-2"}]},{"project":"NCBI-Disease-Corpus-high-o3-1","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-1"}]},{"project":"NCBI-Disease-Corpus-high-o3-2","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-high-o3-2"}]},{"project":"12345","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"12345"},{"subj":"T2","pred":"source","obj":"12345"},{"subj":"T3","pred":"source","obj":"12345"},{"subj":"T4","pred":"source","obj":"12345"},{"subj":"T5","pred":"source","obj":"12345"}]},{"project":"123456","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"123456"},{"subj":"T2","pred":"source","obj":"123456"},{"subj":"T3","pred":"source","obj":"123456"},{"subj":"T4","pred":"source","obj":"123456"},{"subj":"T5","pred":"source","obj":"123456"}]},{"project":"NCBI-Disease-Corpus-GPT5-withguidelines","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"Modifier"},{"id":"T2","span":{"begin":127,"end":148},"obj":"Modifier"},{"id":"T3","span":{"begin":247,"end":260},"obj":"Modifier"},{"id":"T4","span":{"begin":281,"end":302},"obj":"Modifier"},{"id":"T5","span":{"begin":831,"end":852},"obj":"Modifier"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-withguidelines"}]},{"project":"NCBI-Disease-Corpus-GPT5-noguidelines","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"SpecificDisease"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-noguidelines"}]},{"project":"NCBI-Disease-Corpus-GPT5-guidelineprompt","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"Modifier"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-GPT5-guidelineprompt"}]},{"project":"NCBI-Disease-Corpus-Moderated1","denotations":[{"id":"T1","span":{"begin":55,"end":76},"obj":"CompositeMention"},{"id":"T2","span":{"begin":127,"end":148},"obj":"CompositeMention"},{"id":"T3","span":{"begin":247,"end":260},"obj":"Modifier"},{"id":"T4","span":{"begin":281,"end":302},"obj":"CompositeMention"},{"id":"T5","span":{"begin":831,"end":852},"obj":"CompositeMention"}],"attributes":[{"subj":"T1","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T2","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T3","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T4","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"},{"subj":"T5","pred":"source","obj":"NCBI-Disease-Corpus-Moderated1"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"NCBIDiseaseCorpus","color":"#93a6ec","default":true},{"id":"DisGeNET","color":"#c0ec93"},{"id":"NCBI-Disease-Test","color":"#ec93da"},{"id":"NCBI-Disease-Test-Assistant-Knowledge","color":"#93ece4"},{"id":"NCBI-Disease-Test-4o-NoGuidelineInPrompt","color":"#ecca93"},{"id":"NCBI-Disease-Test-4o-GuidelineInPrompt","color":"#b093ec"},{"id":"NCBI-Disease-Corpus-UpdatedGuideline","color":"#93ec96"},{"id":"NCBI-Disease-Corpus-humanintheloop","color":"#ec93a9"},{"id":"NCBI-Disease-Corpus-rezarta1","color":"#93c3ec"},{"id":"NCBI-Disease-Corpus-All","color":"#ddec93"},{"id":"NCBI-Disease-Corpus-2stage-All","color":"#e093ec"},{"id":"NCBI-Disease-Corpus-rezarta-All","color":"#93ecc6"},{"id":"NCBI-Disease-Corpus-4oGuideline-All","color":"#ecac93"},{"id":"NCBI-Disease-Corpus-Simple-All","color":"#9393ec"},{"id":"NCBI-Disease-Corpus-o3-2","color":"#adec93"},{"id":"NCBI-Disease-Corpus-high-o3-1","color":"#ec93c7"},{"id":"NCBI-Disease-Corpus-high-o3-2","color":"#93e1ec"},{"id":"12345","color":"#ecdc93"},{"id":"123456","color":"#c293ec"},{"id":"NCBI-Disease-Corpus-GPT5-withguidelines","color":"#93eca8"},{"id":"NCBI-Disease-Corpus-GPT5-noguidelines","color":"#ec9397"},{"id":"NCBI-Disease-Corpus-GPT5-guidelineprompt","color":"#93b1ec"},{"id":"NCBI-Disease-Corpus-Moderated1","color":"#cbec93"}]}]}}