PubMed:9374467 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	24-29	protein	denotes	NFAT4
T2	45-48	protein	denotes	JNK
T3	82-130	protein	denotes	nuclear factor of activated T cells (NFAT) group
T4	134-155	protein	denotes	transcription factors
T5	188-203	cell_type	denotes	quiescent cells
T6	205-209	protein	denotes	NFAT
T7	329-333	protein	denotes	NFAT
T8	348-359	protein	denotes	phosphatase
T9	360-371	protein	denotes	calcineurin
T10	377-404	protein	denotes	c-Jun amino-terminal kinase
T11	406-409	protein	denotes	JNK
T12	426-431	protein	denotes	NFAT4
T13	472-497	protein	denotes	JNK phosphorylation sites
T14	542-547	protein	denotes	NFAT4
T15	562-565	protein	denotes	JNK
T16	580-608	cell_line	denotes	calcineurin-stimulated cells
T17	637-642	protein	denotes	NFAT4
T18	697-702	protein	denotes	NFAT4
T19	715-726	protein	denotes	calcineurin
T20	745-748	protein	denotes	JNK

Id	Subject	Object	Predicate	Lexical cue
S1	0-77	Sentence	denotes	Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway.
S2	78-204	Sentence	denotes	The nuclear factor of activated T cells (NFAT) group of transcription factors is retained in the cytoplasm of quiescent cells.
S3	205-267	Sentence	denotes	NFAT activation is mediated in part by induced nuclear import.
S4	268-372	Sentence	denotes	This process requires calcium-dependent dephosphorylation of NFAT caused by the phosphatase calcineurin.
S5	373-445	Sentence	denotes	The c-Jun amino-terminal kinase (JNK) phosphorylates NFAT4 on two sites.
S6	446-548	Sentence	denotes	Mutational removal of the JNK phosphorylation sites caused constitutive nuclear localization of NFAT4.
S7	549-643	Sentence	denotes	In contrast, JNK activation in calcineurin-stimulated cells caused nuclear exclusion of NFAT4.
S8	644-777	Sentence	denotes	These findings show that the nuclear accumulation of NFAT4 promoted by calcineurin is opposed by the JNK signal transduction pathway.

Id	Subject	Object	Predicate	Lexical cue
C1	24-29	NP	denotes	NFAT4
C2	41-76	NP	denotes	the JNK signal transduction pathway
C3	329-333	NP	denotes	NFAT
C4	426-431	NP	denotes	NFAT4
C5	542-547	NP	denotes	NFAT4
C6	637-642	NP	denotes	NFAT4
C7	697-702	NP	denotes	NFAT4
C8	741-776	NP	denotes	the JNK signal transduction pathway
R1	C3	C1	coref-ident	NFAT,NFAT4
R2	C4	C3	coref-ident	NFAT4,NFAT
R3	C5	C4	coref-ident	NFAT4,NFAT4
R4	C6	C5	coref-ident	NFAT4,NFAT4
R5	C7	C6	coref-ident	NFAT4,NFAT4
R6	C8	C2	coref-ident	the JNK signal transduction pathway,the JNK signal transduction pathway

Id	Subject	Object	Predicate	Lexical cue
T1	24-29	protein_molecule	denotes	NFAT4
T2	45-48	protein_molecule	denotes	JNK
T3	82-130	protein_family_or_group	denotes	nuclear factor of activated T cells (NFAT) group
T4	134-155	protein_family_or_group	denotes	transcription factors
T5	175-184	cell_component	denotes	cytoplasm
T6	188-203	cell_type	denotes	quiescent cells
T7	205-209	protein_family_or_group	denotes	NFAT
T8	252-266	other_name	denotes	nuclear import
T9	290-297	atom	denotes	calcium
T10	329-333	protein_family_or_group	denotes	NFAT
T11	348-359	protein_family_or_group	denotes	phosphatase
T12	360-371	protein_molecule	denotes	calcineurin
T13	377-404	protein_family_or_group	denotes	c-Jun amino-terminal kinase
T14	406-409	protein_family_or_group	denotes	JNK
T15	426-431	protein_molecule	denotes	NFAT4
T16	472-497	protein_domain_or_region	denotes	JNK phosphorylation sites
T17	542-547	protein_molecule	denotes	NFAT4
T18	562-565	protein_molecule	denotes	JNK
T19	580-591	protein_molecule	denotes	calcineurin
T20	637-642	protein_molecule	denotes	NFAT4
T21	697-702	protein_molecule	denotes	NFAT4
T22	715-726	protein_molecule	denotes	calcineurin
T23	745-748	protein_molecule	denotes	JNK