PubMed:9261375 JSON TXT

Annnotations TAB JSON ListView MergeView

Id	Subject	Object	Predicate	Lexical cue
T1	79-84	protein	denotes	ZEBRA
T2	106-119	cell_type	denotes	B lymphocytes
T3	186-203	protein	denotes	EBV ZEBRA protein
T4	205-210	protein	denotes	ZEBRA
T5	310-315	protein	denotes	ZEBRA
T6	488-493	protein	denotes	ZEBRA
T7	526-596	protein	denotes	heterologous acidic, proline-rich, or glutamine-rich activation domain
T8	598-603	protein	denotes	ZEBRA
T9	645-650	protein	denotes	ZEBRA
T10	691-704	DNA	denotes	EBV promoters
T11	766-782	DNA	denotes	EBV lytic origin
T12	848-853	protein	denotes	ZEBRA
T13	856-884	protein	denotes	N-terminal activation domain
T14	958-968	protein	denotes	subdomains
T15	999-1009	protein	denotes	N terminus

Id	Subject	Object	Predicate	Lexical cue
S1	0-85	Sentence	denotes	Activation domain requirements for disruption of Epstein-Barr virus latency by ZEBRA.
S2	86-204	Sentence	denotes	Latent infection of B lymphocytes by Epstein-Barr virus (EBV) can be disrupted by expression of the EBV ZEBRA protein.
S3	205-309	Sentence	denotes	ZEBRA, a transcriptional activator, initiates the EBV lytic cascade by activating viral gene expression.
S4	310-418	Sentence	denotes	ZEBRA is also indispensable for viral replication and binds directly to the EBV lytic origin of replication.
S5	419-487	Sentence	denotes	The studies described herein demonstrate that the activation domain.
S6	488-597	Sentence	denotes	ZEBRA activation can be replaced by a heterologous acidic, proline-rich, or glutamine-rich activation domain.
S7	598-783	Sentence	denotes	ZEBRA activation domain swap constructs retain ZEBRA's native abilities to activate specific EBV promoters, to disrupt EBV latency, and to stimulate replication at the EBV lytic origin.
S8	784-1076	Sentence	denotes	Additional work, employing sequential and internal deletions of ZEBRA's N-terminal activation domain, indicates that its separate activities are not attributable to specific subdomains but are spread throughout its N terminus and therefore cannot be inactivated by deleting localized regions.

Id	Subject	Object	Predicate	Lexical cue
C1	49-75	NP	denotes	Epstein-Barr virus latency
C2	79-84	NP	denotes	ZEBRA
C3	205-210	NP	denotes	ZEBRA
C4	212-239	NP	denotes	a transcriptional activator
C5	310-315	NP	denotes	ZEBRA
C6	717-728	NP	denotes	EBV latency
C7	784-799	NP	denotes	Additional work
C9	848-884	NP	denotes	ZEBRA's N-terminal activation domain
C8	801-884	NP	denotes	employing sequential and internal deletions of ZEBRA's N-terminal activation domain
C10	901-904	NP	denotes	its
C11	995-998	NP	denotes	its
R1	C3	C2	coref-ident	ZEBRA,ZEBRA
R2	C4	C3	coref-appos	a transcriptional activator,ZEBRA
R3	C5	C3	coref-ident	ZEBRA,ZEBRA
R4	C6	C1	coref-ident	EBV latency,Epstein-Barr virus latency
R5	C8	C7	coref-ident	employing sequential and internal deletions of ZEBRA's N-terminal activation domain,Additional work
R6	C10	C9	coref-pron	its,ZEBRA's N-terminal activation domain
R7	C11	C9	coref-pron	its,ZEBRA's N-terminal activation domain

Id	Subject	Object	Predicate	Lexical cue
T1	49-67	virus	denotes	Epstein-Barr virus
T2	79-84	protein_molecule	denotes	ZEBRA
T3	106-119	cell_type	denotes	B lymphocytes
T4	123-141	virus	denotes	Epstein-Barr virus
T5	143-146	virus	denotes	EBV
T6	186-189	virus	denotes	EBV
T7	190-195	protein_molecule	denotes	ZEBRA
T8	205-210	protein_molecule	denotes	ZEBRA
T9	255-258	virus	denotes	EBV
T10	287-308	other_name	denotes	viral gene expression
T11	310-315	protein_molecule	denotes	ZEBRA
T12	386-389	virus	denotes	EBV
T13	488-493	protein_molecule	denotes	ZEBRA
T14	598-603	protein_molecule	denotes	ZEBRA
T15	645-650	protein_molecule	denotes	ZEBRA
T16	691-694	virus	denotes	EBV
T17	717-720	virus	denotes	EBV
T18	766-769	virus	denotes	EBV
T19	848-853	protein_molecule	denotes	ZEBRA
T20	856-884	protein_domain_or_region	denotes	N-terminal activation domain
T21	958-968	protein_domain_or_region	denotes	subdomains
T22	999-1009	protein_domain_or_region	denotes	N terminus