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sentences

Id Subject Object Predicate Lexical cue
T1 0-142 Sentence denotes Critical cytoplasmic domains of human interleukin-9 receptor alpha chain in interleukin-9-mediated cell proliferation and signal transduction.
T2 143-246 Sentence denotes Interleukin-9 receptor (IL-9R) complex consists of a ligand-specific alpha chain and IL-2R gamma chain.
T3 247-377 Sentence denotes In this study, two regions in the cytoplasmic domain of human IL-9Ralpha were found to be important for IL-9-mediated cell growth.
T4 378-548 Sentence denotes A membrane-proximal region that contains the BOX1 consensus sequence is required for IL-9-induced cell proliferation and tyrosine phosphorylation of Janus kinases (JAKs).
T5 549-678 Sentence denotes Deletion of this region or internal deletion of the BOX1 motif abrogated IL-9-induced cell proliferation and signal transduction.
T6 679-996 Sentence denotes However, substitution of the Pro-X-Pro in the BOX1 motif with Ala-X-Ala failed to abolish IL-9-induced cell proliferation but decreased IL-9-mediated tyrosine phosphorylation of JAK kinases, insulin receptor substrate-2, and signal transducer and activator of transcription 3 (STAT3) and expression of c-myc and junB.
T7 997-1094 Sentence denotes Another important region is downstream of the BOX1 motif and contains a STAT3 binding motif YLPQ.
T8 1095-1274 Sentence denotes Deletion of this region significantly impaired IL-9-induced cell growth, activation of JAK kinases, insulin receptor substrate-2, and STAT3 and expression of early response genes.
T9 1275-1427 Sentence denotes A point mutation changing YLPQ into YLPA greatly reduced IL-9-induced activation of STAT3 and expression of c-myc but did not affect cell proliferation.
T10 1428-1612 Sentence denotes These results suggest that cooperation or cross-talk of signaling molecules associated with different domains of IL-9Ralpha other than STAT3 is essential for IL-9-mediated cell growth.
T1 0-142 Sentence denotes Critical cytoplasmic domains of human interleukin-9 receptor alpha chain in interleukin-9-mediated cell proliferation and signal transduction.
T2 143-246 Sentence denotes Interleukin-9 receptor (IL-9R) complex consists of a ligand-specific alpha chain and IL-2R gamma chain.
T3 247-377 Sentence denotes In this study, two regions in the cytoplasmic domain of human IL-9Ralpha were found to be important for IL-9-mediated cell growth.
T4 378-548 Sentence denotes A membrane-proximal region that contains the BOX1 consensus sequence is required for IL-9-induced cell proliferation and tyrosine phosphorylation of Janus kinases (JAKs).
T5 549-678 Sentence denotes Deletion of this region or internal deletion of the BOX1 motif abrogated IL-9-induced cell proliferation and signal transduction.
T6 679-996 Sentence denotes However, substitution of the Pro-X-Pro in the BOX1 motif with Ala-X-Ala failed to abolish IL-9-induced cell proliferation but decreased IL-9-mediated tyrosine phosphorylation of JAK kinases, insulin receptor substrate-2, and signal transducer and activator of transcription 3 (STAT3) and expression of c-myc and junB.
T7 997-1094 Sentence denotes Another important region is downstream of the BOX1 motif and contains a STAT3 binding motif YLPQ.
T8 1095-1274 Sentence denotes Deletion of this region significantly impaired IL-9-induced cell growth, activation of JAK kinases, insulin receptor substrate-2, and STAT3 and expression of early response genes.
T9 1275-1427 Sentence denotes A point mutation changing YLPQ into YLPA greatly reduced IL-9-induced activation of STAT3 and expression of c-myc but did not affect cell proliferation.
T10 1428-1612 Sentence denotes These results suggest that cooperation or cross-talk of signaling molecules associated with different domains of IL-9Ralpha other than STAT3 is essential for IL-9-mediated cell growth.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 389-397 http://purl.obolibrary.org/obo/MAT_0000491 denotes proximal

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 9-28 protein denotes cytoplasmic domains
T2 32-72 protein denotes human interleukin-9 receptor alpha chain
T3 76-87 protein denotes interleukin
T4 143-181 protein denotes Interleukin-9 receptor (IL-9R) complex
T5 196-223 protein denotes ligand-specific alpha chain
T6 228-245 protein denotes IL-2R gamma chain
T7 281-299 protein denotes cytoplasmic domain
T8 303-319 protein denotes human IL-9Ralpha
T9 351-355 protein denotes IL-9
T10 380-404 protein denotes membrane-proximal region
T11 423-446 protein denotes BOX1 consensus sequence
T12 463-467 protein denotes IL-9
T13 527-540 protein denotes Janus kinases
T14 542-546 protein denotes JAKs
T15 601-611 protein denotes BOX1 motif
T16 622-626 protein denotes IL-9
T17 708-717 protein denotes Pro-X-Pro
T18 725-735 protein denotes BOX1 motif
T19 741-750 protein denotes Ala-X-Ala
T20 769-773 protein denotes IL-9
T21 815-819 protein denotes IL-9
T22 857-868 protein denotes JAK kinases
T23 870-898 protein denotes insulin receptor substrate-2
T24 904-954 protein denotes signal transducer and activator of transcription 3
T25 956-961 protein denotes STAT3
T26 981-986 DNA denotes c-myc
T27 991-995 DNA denotes junB
T28 1043-1053 protein denotes BOX1 motif
T29 1069-1088 DNA denotes STAT3 binding motif
T30 1089-1093 DNA denotes YLPQ
T31 1142-1146 protein denotes IL-9
T32 1182-1193 protein denotes JAK kinases
T33 1195-1223 protein denotes insulin receptor substrate-2
T34 1229-1234 protein denotes STAT3
T35 1253-1273 DNA denotes early response genes
T36 1301-1305 DNA denotes YLPQ
T37 1311-1315 DNA denotes YLPA
T38 1332-1336 protein denotes IL-9
T39 1359-1364 protein denotes STAT3
T40 1383-1388 DNA denotes c-myc
T41 1541-1551 protein denotes IL-9Ralpha
T42 1563-1568 protein denotes STAT3
T43 1586-1590 protein denotes IL-9

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 351-376 NP denotes IL-9-mediated cell growth
C3 378-404 NP denotes A membrane-proximal region
C4 405-409 NP denotes that
C2 378-446 NP denotes A membrane-proximal region that contains the BOX1 consensus sequence
C5 463-494 NP denotes IL-9-induced cell proliferation
C6 561-572 NP denotes this region
C7 597-611 NP denotes the BOX1 motif
C8 622-653 NP denotes IL-9-induced cell proliferation
C9 721-735 NP denotes the BOX1 motif
C10 769-800 NP denotes IL-9-induced cell proliferation
C11 857-868 NP denotes JAK kinases
C12 870-898 NP denotes insulin receptor substrate-2
C13 904-986 NP denotes signal transducer and activator of transcription 3 (STAT3) and expression of c-myc
C14 997-1021 NP denotes Another important region
C15 1039-1053 NP denotes the BOX1 motif
C16 1067-1093 NP denotes a STAT3 binding motif YLPQ
C17 1107-1118 NP denotes this region
C18 1182-1193 NP denotes JAK kinases
C19 1195-1223 NP denotes insulin receptor substrate-2
C20 1301-1305 NP denotes YLPQ
C21 1359-1388 NP denotes STAT3 and expression of c-myc
C22 1586-1611 NP denotes IL-9-mediated cell growth
R1 C4 C3 coref-relat that,A membrane-proximal region
R2 C6 C2 coref-ident this region,A membrane-proximal region that contains the BOX1 consensus sequence
R3 C8 C5 coref-ident IL-9-induced cell proliferation,IL-9-induced cell proliferation
R4 C9 C7 coref-ident the BOX1 motif,the BOX1 motif
R5 C10 C8 coref-ident IL-9-induced cell proliferation,IL-9-induced cell proliferation
R6 C15 C9 coref-ident the BOX1 motif,the BOX1 motif
R7 C17 C14 coref-ident this region,Another important region
R8 C18 C11 coref-ident JAK kinases,JAK kinases
R9 C19 C12 coref-ident insulin receptor substrate-2,insulin receptor substrate-2
R10 C20 C16 coref-ident YLPQ,a STAT3 binding motif YLPQ
R11 C21 C13 coref-ident STAT3 and expression of c-myc,signal transducer and activator of transcription 3 (STAT3) and expression of c-myc
R12 C22 C1 coref-ident IL-9-mediated cell growth,IL-9-mediated cell growth

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-142 Sentence denotes Critical cytoplasmic domains of human interleukin-9 receptor alpha chain in interleukin-9-mediated cell proliferation and signal transduction.
S2 143-246 Sentence denotes Interleukin-9 receptor (IL-9R) complex consists of a ligand-specific alpha chain and IL-2R gamma chain.
S3 247-377 Sentence denotes In this study, two regions in the cytoplasmic domain of human IL-9Ralpha were found to be important for IL-9-mediated cell growth.
S4 378-548 Sentence denotes A membrane-proximal region that contains the BOX1 consensus sequence is required for IL-9-induced cell proliferation and tyrosine phosphorylation of Janus kinases (JAKs).
S5 549-678 Sentence denotes Deletion of this region or internal deletion of the BOX1 motif abrogated IL-9-induced cell proliferation and signal transduction.
S6 679-996 Sentence denotes However, substitution of the Pro-X-Pro in the BOX1 motif with Ala-X-Ala failed to abolish IL-9-induced cell proliferation but decreased IL-9-mediated tyrosine phosphorylation of JAK kinases, insulin receptor substrate-2, and signal transducer and activator of transcription 3 (STAT3) and expression of c-myc and junB.
S7 997-1094 Sentence denotes Another important region is downstream of the BOX1 motif and contains a STAT3 binding motif YLPQ.
S8 1095-1274 Sentence denotes Deletion of this region significantly impaired IL-9-induced cell growth, activation of JAK kinases, insulin receptor substrate-2, and STAT3 and expression of early response genes.
S9 1275-1427 Sentence denotes A point mutation changing YLPQ into YLPA greatly reduced IL-9-induced activation of STAT3 and expression of c-myc but did not affect cell proliferation.
S10 1428-1612 Sentence denotes These results suggest that cooperation or cross-talk of signaling molecules associated with different domains of IL-9Ralpha other than STAT3 is essential for IL-9-mediated cell growth.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 9-28 protein_domain_or_region denotes cytoplasmic domains
T2 32-72 protein_subunit denotes human interleukin-9 receptor alpha chain
T3 76-87 protein_family_or_group denotes interleukin
T4 143-181 protein_complex denotes Interleukin-9 receptor (IL-9R) complex
T5 196-223 protein_subunit denotes ligand-specific alpha chain
T6 228-245 protein_subunit denotes IL-2R gamma chain
T7 281-299 protein_domain_or_region denotes cytoplasmic domain
T8 303-319 protein_subunit denotes human IL-9Ralpha
T9 351-355 protein_molecule denotes IL-9
T10 380-404 protein_domain_or_region denotes membrane-proximal region
T11 423-446 protein_domain_or_region denotes BOX1 consensus sequence
T12 463-467 protein_molecule denotes IL-9
T13 499-507 amino_acid_monomer denotes tyrosine
T14 527-540 protein_family_or_group denotes Janus kinases
T15 542-546 protein_family_or_group denotes JAKs
T16 601-611 protein_domain_or_region denotes BOX1 motif
T17 622-626 protein_molecule denotes IL-9
T18 708-717 protein_domain_or_region denotes Pro-X-Pro
T19 725-735 protein_domain_or_region denotes BOX1 motif
T20 741-750 protein_domain_or_region denotes Ala-X-Ala
T21 769-773 protein_molecule denotes IL-9
T22 815-819 protein_molecule denotes IL-9
T23 829-837 amino_acid_monomer denotes tyrosine
T24 857-868 protein_family_or_group denotes JAK kinases
T25 870-898 protein_molecule denotes insulin receptor substrate-2
T26 904-954 protein_molecule denotes signal transducer and activator of transcription 3
T27 956-961 protein_molecule denotes STAT3
T28 981-986 DNA_domain_or_region denotes c-myc
T29 991-995 DNA_domain_or_region denotes junB
T30 1043-1053 protein_domain_or_region denotes BOX1 motif
T31 1069-1074 protein_molecule denotes STAT3
T32 1089-1093 DNA_domain_or_region denotes YLPQ
T33 1142-1146 protein_molecule denotes IL-9
T34 1182-1193 protein_family_or_group denotes JAK kinases
T35 1195-1223 protein_molecule denotes insulin receptor substrate-2
T36 1229-1234 protein_molecule denotes STAT3
T37 1253-1273 DNA_family_or_group denotes early response genes
T38 1301-1305 DNA_domain_or_region denotes YLPQ
T39 1311-1315 DNA_domain_or_region denotes YLPA
T40 1332-1336 protein_molecule denotes IL-9
T41 1359-1364 protein_molecule denotes STAT3
T42 1383-1388 DNA_domain_or_region denotes c-myc
T43 1408-1426 other_name denotes cell proliferation
T44 1541-1551 protein_subunit denotes IL-9Ralpha
T45 1563-1568 protein_molecule denotes STAT3
T46 1586-1590 protein_molecule denotes IL-9

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 389-397 Body_part denotes proximal http://purl.obolibrary.org/obo/MAT_0000491

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 32-37 OrganismTaxon denotes human 9606
T2 303-308 OrganismTaxon denotes human 9606
T3 527-532 OrganismTaxon denotes Janus 1385265

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 9-20 Body_part denotes cytoplasmic http://purl.obolibrary.org/obo/GO_0005737
T2 281-292 Body_part denotes cytoplasmic http://purl.obolibrary.org/obo/GO_0005737
T3 380-388 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158