PubMed:9234727 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/9234727","sourcedb":"PubMed","sourceid":"9234727","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/9234727","text":"The product of the murine homolog of the Drosophila extra sex combs gene displays transcriptional repressor activity.\nThe heterogeneous nuclear ribonucleoprotein K protein represents a novel class of proteins that may act as docking platforms that orchestrate cross-talk among molecules involved in signal transduction and gene expression. Using a fragment of K protein as bait in the yeast two-hybrid screen, we isolated a cDNA that encodes a protein whose primary structure has extensive similarity to the Drosophila melanogaster extra sex combs (esc) gene product, Esc, a putative silencer of homeotic genes. The cDNA that we isolated is identical to the cDNA of the recently positionally cloned mouse embryonic ectoderm development gene, eed. 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