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PubMed:9231664 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 86-152 protein denotes hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6
T2 198-224 protein denotes hepatocyte nuclear factors
T3 225-235 protein denotes HNF-1alpha
T4 240-250 protein denotes HNF-4alpha
T5 332-368 protein denotes liver-enriched transcription factors
T6 816-860 protein denotes HNF-3alpha, -3beta, -3gamma, -4gamma, and -6
T7 878-899 cell_type denotes pancreatic beta-cells
T8 954-992 DNA denotes simple tandem repeat DNA polymorphisms
T9 1015-1025 protein denotes HNF-3alpha
T10 1027-1033 protein denotes -3beta
T11 1035-1042 protein denotes -3gamma
T12 1044-1051 protein denotes -4gamma
T13 1057-1059 protein denotes -6
T14 1079-1084 protein denotes HNF-6
T15 1088-1104 DNA denotes chromosome bands
T16 1105-1117 DNA denotes 15q21.1-21.2

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 67-152 NP denotes the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6
C2 154-250 NP denotes The genes encoding the functionally related hepatocyte nuclear factors HNF-1alpha and HNF-4alpha
C3 326-368 NP denotes these liver-enriched transcription factors
C5 379-482 NP denotes two forms of early-onset type 2 diabetes (maturity-onset diabetes of the young [MODY]), MODY3 and MODY1
C6 484-489 NP denotes which
C4 379-613 NP denotes two forms of early-onset type 2 diabetes (maturity-onset diabetes of the young [MODY]), MODY3 and MODY1, which are characterized by impaired glucose-stimulated insulin secretion, early disease onset, and autosomal dominant inheritance
C7 648-652 NP denotes HNFs
C8 816-860 NP denotes HNF-3alpha, -3beta, -3gamma, -4gamma, and -6
C9 996-1059 NP denotes the genes encoding HNF-3alpha, -3beta, -3gamma, -4gamma, and -6
C10 1228-1239 NP denotes these genes
C11 1263-1278 NP denotes type 2 diabetes
R1 C3 C2 coref-ident these liver-enriched transcription factors,The genes encoding the functionally related hepatocyte nuclear factors HNF-1alpha and HNF-4alpha
R2 C6 C5 coref-relat which,"two forms of early-onset type 2 diabetes (maturity-onset diabetes of the young [MODY]), MODY3 and MODY1"
R3 C7 C1 coref-ident HNFs,"the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6"
R4 C8 C7 coref-ident "HNF-3alpha, -3beta, -3gamma, -4gamma, and -6",HNFs
R5 C9 C8 coref-ident "the genes encoding HNF-3alpha, -3beta, -3gamma, -4gamma, and -6","HNF-3alpha, -3beta, -3gamma, -4gamma, and -6"
R6 C10 C9 coref-ident these genes,"the genes encoding HNF-3alpha, -3beta, -3gamma, -4gamma, and -6"
R7 C11 C4 coref-ident type 2 diabetes,"two forms of early-onset type 2 diabetes (maturity-onset diabetes of the young [MODY]), MODY3 and MODY1, which are characterized by impaired glucose-stimulated insulin secretion, early disease onset, and autosomal dominant inheritance"

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-153 Sentence denotes Pancreatic islet expression studies and polymorphic DNA markers in the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6.
S2 154-312 Sentence denotes The genes encoding the functionally related hepatocyte nuclear factors HNF-1alpha and HNF-4alpha play a critical role in normal pancreatic beta-cell function.
S3 313-614 Sentence denotes Mutations in these liver-enriched transcription factors result in two forms of early-onset type 2 diabetes (maturity-onset diabetes of the young [MODY]), MODY3 and MODY1, which are characterized by impaired glucose-stimulated insulin secretion, early disease onset, and autosomal dominant inheritance.
S4 615-787 Sentence denotes The transcriptional hierarchy of HNFs suggests that other proteins of the regulatory cascade might be responsible for other forms of MODY and/or late-onset type 2 diabetes.
S5 788-900 Sentence denotes In this study, we show that HNF-3alpha, -3beta, -3gamma, -4gamma, and -6 are expressed in pancreatic beta-cells.
S6 901-1156 Sentence denotes We report the identification and characterization of simple tandem repeat DNA polymorphisms in the genes encoding HNF-3alpha, -3beta, -3gamma, -4gamma, and -6 and the mapping of HNF-6 to chromosome bands 15q21.1-21.2 by fluorescence in situ hybridization.
S7 1157-1279 Sentence denotes These markers will be useful to study the role of genetic variation in these genes in the pathogenesis of type 2 diabetes.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-16 body_part denotes Pancreatic islet
T2 40-63 other_name denotes polymorphic DNA markers
T3 198-224 protein_family_or_group denotes hepatocyte nuclear factors
T4 225-235 protein_molecule denotes HNF-1alpha
T5 240-250 protein_molecule denotes HNF-4alpha
T6 282-311 other_name denotes pancreatic beta-cell function
T7 332-337 body_part denotes liver
T8 392-419 other_name denotes early-onset type 2 diabetes
T9 421-444 other_name denotes maturity-onset diabetes
T10 459-463 other_name denotes MODY
T11 467-472 other_name denotes MODY3
T12 477-482 other_name denotes MODY1
T13 520-556 other_name denotes glucose-stimulated insulin secretion
T14 583-613 other_name denotes autosomal dominant inheritance
T15 619-644 other_name denotes transcriptional hierarchy
T16 648-652 other_name denotes HNFs
T17 689-707 other_name denotes regulatory cascade
T18 748-752 other_name denotes MODY
T19 760-786 other_name denotes late-onset type 2 diabetes
T20 878-899 cell_type denotes pancreatic beta-cells
T21 954-992 DNA_family_or_group denotes simple tandem repeat DNA polymorphisms
T22 1015-1025 protein_molecule denotes HNF-3alpha
T23 1027-1033 protein_molecule denotes -3beta
T24 1035-1042 protein_molecule denotes -3gamma
T25 1044-1051 protein_molecule denotes -4gamma
T26 1057-1059 protein_molecule denotes -6
T27 1079-1084 protein_molecule denotes HNF-6
T28 1088-1104 DNA_domain_or_region denotes chromosome bands
T29 1105-1117 DNA_domain_or_region denotes 15q21.1-21.2
T30 1121-1155 other_name denotes fluorescence in situ hybridization
T31 1207-1224 other_name denotes genetic variation
T32 1263-1278 other_name denotes type 2 diabetes