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PubMed:9134429 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 152-159 https://glytoucan.org/Structures/Glycans/G00048MO denotes Lewis b
T2 152-159 https://glytoucan.org/Structures/Glycans/G39211DH denotes Lewis b
T3 161-168 https://glytoucan.org/Structures/Glycans/G00052MO denotes Lewis Y
T4 161-168 https://glytoucan.org/Structures/Glycans/G89659QV denotes Lewis Y
T5 614-624 https://glytoucan.org/Structures/Glycans/G46868TY denotes H antigens
T6 656-667 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T7 752-762 https://glytoucan.org/Structures/Glycans/G46868TY denotes H antigens

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 152-159 Glycan_Motif denotes Lewis b https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G39211DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00048MO
T3 161-168 Glycan_Motif denotes Lewis Y https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G89659QV
T4 614-624 Glycan_Motif denotes H antigens https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46868TY
T5 656-667 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T6 752-762 Glycan_Motif denotes H antigens https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46868TY

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-104 Sentence denotes Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
TextSentencer_T2 105-344 Sentence denotes Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens.
TextSentencer_T3 345-434 Sentence denotes Yet the biological significance of alpha(1-2) fucosylated structures is not well defined.
TextSentencer_T4 435-569 Sentence denotes We have transfected a poorly tumorigenic rat colon carcinoma cell line with the human H blood group alpha(1-2)fucosyltransferase cDNA.
TextSentencer_T5 570-707 Sentence denotes This resulted in cell surface expression of H antigens with a concomitant decrease of sialic acid substituted and free beta-galactosides.
TextSentencer_T6 708-855 Sentence denotes Immunoprecipitation experiments showed that H antigens were essentially borne by variants of CD44 carrying amino acid sequences encoded by exon v6.
TextSentencer_T7 856-973 Sentence denotes The transfected cells showed increased motility in a wound healing assay, without changing their proliferation rates.
TextSentencer_T8 974-1137 Sentence denotes Parental and control cells transfected with an empty vector formed small tumors that always regressed after 30 days when injected subcutaneously to syngeneic rats.
TextSentencer_T9 1138-1231 Sentence denotes In contrast, alpha(1-2)fucosyltransferase transfectants were able to form progressive tumors.
TextSentencer_T10 1232-1287 Sentence denotes Increased tumorigenicity was also visible in nude mice.
TextSentencer_T11 1288-1413 Sentence denotes These results demonstrate that alpha(1-2)fucosylated antigens contribute directly to aggressiveness of colon carcinoma cells.
TextSentencer_T12 1414-1471 Sentence denotes This could occur by altering a function of CD44 variants.
T1 0-104 Sentence denotes Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
T2 105-344 Sentence denotes Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens.
T3 345-434 Sentence denotes Yet the biological significance of alpha(1-2) fucosylated structures is not well defined.
T4 435-569 Sentence denotes We have transfected a poorly tumorigenic rat colon carcinoma cell line with the human H blood group alpha(1-2)fucosyltransferase cDNA.
T5 570-707 Sentence denotes This resulted in cell surface expression of H antigens with a concomitant decrease of sialic acid substituted and free beta-galactosides.
T6 708-855 Sentence denotes Immunoprecipitation experiments showed that H antigens were essentially borne by variants of CD44 carrying amino acid sequences encoded by exon v6.
T7 856-973 Sentence denotes The transfected cells showed increased motility in a wound healing assay, without changing their proliferation rates.
T8 974-1137 Sentence denotes Parental and control cells transfected with an empty vector formed small tumors that always regressed after 30 days when injected subcutaneously to syngeneic rats.
T9 1138-1231 Sentence denotes In contrast, alpha(1-2)fucosyltransferase transfectants were able to form progressive tumors.
T10 1232-1287 Sentence denotes Increased tumorigenicity was also visible in nude mice.
T11 1288-1413 Sentence denotes These results demonstrate that alpha(1-2)fucosylated antigens contribute directly to aggressiveness of colon carcinoma cells.
T12 1414-1471 Sentence denotes This could occur by altering a function of CD44 variants.
T1 0-104 Sentence denotes Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
T2 105-344 Sentence denotes Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens.
T3 345-434 Sentence denotes Yet the biological significance of alpha(1-2) fucosylated structures is not well defined.
T4 435-569 Sentence denotes We have transfected a poorly tumorigenic rat colon carcinoma cell line with the human H blood group alpha(1-2)fucosyltransferase cDNA.
T5 570-707 Sentence denotes This resulted in cell surface expression of H antigens with a concomitant decrease of sialic acid substituted and free beta-galactosides.
T6 708-855 Sentence denotes Immunoprecipitation experiments showed that H antigens were essentially borne by variants of CD44 carrying amino acid sequences encoded by exon v6.
T7 856-973 Sentence denotes The transfected cells showed increased motility in a wound healing assay, without changing their proliferation rates.
T8 974-1137 Sentence denotes Parental and control cells transfected with an empty vector formed small tumors that always regressed after 30 days when injected subcutaneously to syngeneic rats.
T9 1138-1231 Sentence denotes In contrast, alpha(1-2)fucosyltransferase transfectants were able to form progressive tumors.
T10 1232-1287 Sentence denotes Increased tumorigenicity was also visible in nude mice.
T11 1288-1413 Sentence denotes These results demonstrate that alpha(1-2)fucosylated antigens contribute directly to aggressiveness of colon carcinoma cells.
T12 1414-1471 Sentence denotes This could occur by altering a function of CD44 variants.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 152-159 https://glytoucan.org/Structures/Glycans/G00048MO denotes Lewis b
T2 152-159 https://glytoucan.org/Structures/Glycans/G39211DH denotes Lewis b
T3 161-168 https://glytoucan.org/Structures/Glycans/G00052MO denotes Lewis Y
T4 161-168 https://glytoucan.org/Structures/Glycans/G89659QV denotes Lewis Y
T5 614-624 https://glytoucan.org/Structures/Glycans/G46868TY denotes H antigens
T6 656-667 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T7 752-762 https://glytoucan.org/Structures/Glycans/G46868TY denotes H antigens

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 152-159 http://www.glycoepitope.jp/epitopes/EP0010 denotes Lewis b
T2 161-168 http://www.glycoepitope.jp/epitopes/EP0018 denotes Lewis Y

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 16-21 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T2 123-128 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T3 123-128 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T4 190-195 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T5 480-485 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T6 523-528 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T7 523-528 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T8 1391-1396 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1319-1326 gene:146 denotes alpha(1
T1 1391-1406 disease:C0699790 denotes colon carcinoma
R1 T0 T1 associated_with alpha(1,colon carcinoma

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 16-21 FMAID:104231 denotes colon
_T2 16-21 FMAID:14543 denotes colon
_T3 32-37 FMAID:68646 denotes cells
_T4 32-37 FMAID:169002 denotes cells
_T5 86-90 FMAID:198663 denotes gene
_T6 123-128 FMAID:256053 denotes blood
_T7 190-195 FMAID:104231 denotes colon
_T8 190-195 FMAID:14543 denotes colon
_T9 480-485 FMAID:14543 denotes colon
_T10 480-485 FMAID:104231 denotes colon
_T11 523-528 FMAID:256053 denotes blood
_T12 587-599 FMAID:200942 denotes cell surface
_T13 587-599 FMAID:212684 denotes cell surface
_T14 592-599 FMAID:146300 denotes surface
_T15 592-599 FMAID:50594 denotes surface
_T16 815-825 FMAID:82739 denotes amino acid
_T17 815-825 FMAID:196728 denotes amino acid
_T18 847-851 FMAID:84120 denotes exon
_T19 847-851 FMAID:198073 denotes exon
_T20 852-854 FMAID:102842 denotes v6
_T21 872-877 FMAID:68646 denotes cells
_T22 872-877 FMAID:169002 denotes cells
_T23 967-972 FMAID:217859 denotes rates
_T24 995-1000 FMAID:169002 denotes cells
_T25 995-1000 FMAID:68646 denotes cells
_T26 1391-1396 FMAID:14543 denotes colon
_T27 1391-1396 FMAID:104231 denotes colon
_T28 1407-1412 FMAID:169002 denotes cells
_T29 1407-1412 FMAID:68646 denotes cells

uniprot-human

Id Subject Object Predicate Lexical cue
T1 56-65 http://www.uniprot.org/uniprot/Q05639 denotes alpha(1-2
T2 253-262 http://www.uniprot.org/uniprot/Q05639 denotes alpha(1-2
T3 380-389 http://www.uniprot.org/uniprot/Q05639 denotes alpha(1-2
T4 535-544 http://www.uniprot.org/uniprot/Q05639 denotes alpha(1-2
T5 1151-1160 http://www.uniprot.org/uniprot/Q05639 denotes alpha(1-2
T6 1319-1328 http://www.uniprot.org/uniprot/Q05639 denotes alpha(1-2
T7 64-85 http://www.uniprot.org/uniprot/Q10981 denotes 2) fucosyltransferase
T8 261-281 http://www.uniprot.org/uniprot/Q10981 denotes 2)fucosyltransferase
T9 543-563 http://www.uniprot.org/uniprot/Q10981 denotes 2)fucosyltransferase
T10 1159-1179 http://www.uniprot.org/uniprot/Q10981 denotes 2)fucosyltransferase
T11 801-805 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T12 1457-1461 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 64-85 http://www.uniprot.org/uniprot/Q9JL27 denotes 2) fucosyltransferase
T2 261-281 http://www.uniprot.org/uniprot/Q9JL27 denotes 2)fucosyltransferase
T3 543-563 http://www.uniprot.org/uniprot/Q9JL27 denotes 2)fucosyltransferase
T4 1159-1179 http://www.uniprot.org/uniprot/Q9JL27 denotes 2)fucosyltransferase
T5 801-805 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T6 1457-1461 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T7 1277-1281 http://www.uniprot.org/uniprot/Q9CZA6 denotes nude

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 22-31 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T2 32-37 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 129-134 http://purl.bioontology.org/ontology/STY/T096 denotes group
T4 196-205 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T5 486-495 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T6 529-534 http://purl.bioontology.org/ontology/STY/T096 denotes group
T7 689-693 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T8 689-693 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T9 815-835 http://purl.bioontology.org/ontology/STY/T087 denotes amino acid sequences
T10 872-877 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T11 995-1000 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T12 1085-1089 http://purl.bioontology.org/ontology/NCBITAXON/82391 denotes days
T13 1397-1406 http://purl.bioontology.org/ontology/NCBITAXON/166034 denotes carcinoma
T14 1407-1412 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 105-116 http://purl.obolibrary.org/obo/GO_0036065 denotes Fucosylated
T2 391-402 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T3 1329-1340 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T4 253-281 http://purl.obolibrary.org/obo/GO_0031127 denotes alpha(1-2)fucosyltransferase
T5 535-563 http://purl.obolibrary.org/obo/GO_0031127 denotes alpha(1-2)fucosyltransferase
T6 253-290 http://purl.obolibrary.org/obo/GO_0031127 denotes alpha(1-2)fucosyltransferase activity
T7 253-290 http://purl.obolibrary.org/obo/GO_0008107 denotes alpha(1-2)fucosyltransferase activity
T8 263-290 http://purl.obolibrary.org/obo/GO_0008417 denotes fucosyltransferase activity
T9 313-325 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T10 909-922 http://purl.obolibrary.org/obo/GO_0042060 denotes wound healing
T11 1373-1387 http://purl.obolibrary.org/obo/GO_0002118 denotes aggressiveness

GO-CC

Id Subject Object Predicate Lexical cue
T1 32-37 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 872-877 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 995-1000 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 496-500 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5 587-591 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6 587-599 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 16-21 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T2 190-195 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T3 480-485 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T4 1391-1396 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T5 123-128 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T6 523-528 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
9134429-3#100#128#gene2524 535-563 gene2524 denotes alpha(1-2)fucosyltransferase
9134429-3#45#60#diseaseC0699790 480-495 diseaseC0699790 denotes colon carcinoma
100#128#gene252445#60#diseaseC0699790 9134429-3#100#128#gene2524 9134429-3#45#60#diseaseC0699790 associated_with alpha(1-2)fucosyltransferase,colon carcinoma

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 16-21 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T2 123-128 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T3 123-128 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T4 190-195 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T5 480-485 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T6 523-528 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood
T7 523-528 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T8 1391-1396 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 123-134 http://rdf.glycoinfo.org/glycan/G00066MO denotes blood group
T2 523-534 http://rdf.glycoinfo.org/glycan/G00066MO denotes blood group
T3 152-157 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T4 161-166 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T5 152-159 http://rdf.glycoinfo.org/glycan/G00048MO denotes Lewis b
T6 161-168 http://rdf.glycoinfo.org/glycan/G00052MO denotes Lewis Y

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 152-159 http://www.glycoepitope.jp/epitopes/EP0010 denotes Lewis b
PD-GlycoEpitope-B_T2 161-168 http://www.glycoepitope.jp/epitopes/EP0018 denotes Lewis Y

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 123-128 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 523-528 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T3 16-21 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
PD-UBERON-AE-B_T4 190-195 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
PD-UBERON-AE-B_T5 480-485 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
PD-UBERON-AE-B_T6 1391-1396 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 16-21 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T2 123-128 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315
T4 190-195 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T5 480-485 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T6 523-528 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315
T8 1391-1396 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 22-31 Phenotype denotes carcinoma HP:0030731
T2 196-205 Phenotype denotes carcinoma HP:0030731
T3 486-495 Phenotype denotes carcinoma HP:0030731
T4 1373-1387 Phenotype denotes aggressiveness HP:0000718
T5 1397-1406 Phenotype denotes carcinoma HP:0030731

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 16-31 Disease denotes colon carcinoma http://purl.obolibrary.org/obo/MONDO_0002032
T2 190-205 Disease denotes colon carcinoma http://purl.obolibrary.org/obo/MONDO_0002032
T3 480-495 Disease denotes colon carcinoma http://purl.obolibrary.org/obo/MONDO_0002032
T4 909-914 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178
T5 1047-1053 Disease denotes tumors http://purl.obolibrary.org/obo/MONDO_0005070
T6 1224-1230 Disease denotes tumors http://purl.obolibrary.org/obo/MONDO_0005070
T7 1391-1406 Disease denotes colon carcinoma http://purl.obolibrary.org/obo/MONDO_0002032

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 152-159 Glycan denotes Lewis b https://api.glycosmos.org/wurcs2image/latest/png/binary/G00048MO
T2 161-168 Glycan denotes Lewis Y https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 152-159 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis b http://www.glycoepitope.jp/epitopes/EP0010
T2 161-168 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis Y http://www.glycoepitope.jp/epitopes/EP0018

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 22-31 Phenotype denotes carcinoma HP:0030731
T2 196-205 Phenotype denotes carcinoma HP:0030731
T3 486-495 Phenotype denotes carcinoma HP:0030731
T4 1373-1387 Phenotype denotes aggressiveness HP:0000718
T5 1397-1406 Phenotype denotes carcinoma HP:0030731

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 12-15 OrganismTaxon denotes rat 10114|10116
T3 476-479 OrganismTaxon denotes rat 10114|10116
T5 515-520 OrganismTaxon denotes human 9606
T6 1132-1136 OrganismTaxon denotes rats 10114|10116
T8 1282-1286 OrganismTaxon denotes mice 10088

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 16-21 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T2 123-128 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 190-195 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T4 480-485 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T5 523-528 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T6 1391-1396 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-104 Sentence denotes Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
TextSentencer_T2 105-344 Sentence denotes Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens.
TextSentencer_T3 345-434 Sentence denotes Yet the biological significance of alpha(1-2) fucosylated structures is not well defined.
TextSentencer_T4 435-569 Sentence denotes We have transfected a poorly tumorigenic rat colon carcinoma cell line with the human H blood group alpha(1-2)fucosyltransferase cDNA.
TextSentencer_T5 570-707 Sentence denotes This resulted in cell surface expression of H antigens with a concomitant decrease of sialic acid substituted and free beta-galactosides.
TextSentencer_T6 708-855 Sentence denotes Immunoprecipitation experiments showed that H antigens were essentially borne by variants of CD44 carrying amino acid sequences encoded by exon v6.
TextSentencer_T7 856-973 Sentence denotes The transfected cells showed increased motility in a wound healing assay, without changing their proliferation rates.
TextSentencer_T8 974-1137 Sentence denotes Parental and control cells transfected with an empty vector formed small tumors that always regressed after 30 days when injected subcutaneously to syngeneic rats.
TextSentencer_T9 1138-1231 Sentence denotes In contrast, alpha(1-2)fucosyltransferase transfectants were able to form progressive tumors.
TextSentencer_T10 1232-1287 Sentence denotes Increased tumorigenicity was also visible in nude mice.
TextSentencer_T11 1288-1413 Sentence denotes These results demonstrate that alpha(1-2)fucosylated antigens contribute directly to aggressiveness of colon carcinoma cells.
TextSentencer_T12 1414-1471 Sentence denotes This could occur by altering a function of CD44 variants.
T1 0-104 Sentence denotes Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
T2 105-344 Sentence denotes Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens.
T3 345-434 Sentence denotes Yet the biological significance of alpha(1-2) fucosylated structures is not well defined.
T4 435-569 Sentence denotes We have transfected a poorly tumorigenic rat colon carcinoma cell line with the human H blood group alpha(1-2)fucosyltransferase cDNA.
T5 570-707 Sentence denotes This resulted in cell surface expression of H antigens with a concomitant decrease of sialic acid substituted and free beta-galactosides.
T6 708-855 Sentence denotes Immunoprecipitation experiments showed that H antigens were essentially borne by variants of CD44 carrying amino acid sequences encoded by exon v6.
T7 856-973 Sentence denotes The transfected cells showed increased motility in a wound healing assay, without changing their proliferation rates.
T8 974-1137 Sentence denotes Parental and control cells transfected with an empty vector formed small tumors that always regressed after 30 days when injected subcutaneously to syngeneic rats.
T9 1138-1231 Sentence denotes In contrast, alpha(1-2)fucosyltransferase transfectants were able to form progressive tumors.
T10 1232-1287 Sentence denotes Increased tumorigenicity was also visible in nude mice.
T11 1288-1413 Sentence denotes These results demonstrate that alpha(1-2)fucosylated antigens contribute directly to aggressiveness of colon carcinoma cells.
T12 1414-1471 Sentence denotes This could occur by altering a function of CD44 variants.
T1 0-104 Sentence denotes Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
T2 105-344 Sentence denotes Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens.
T3 345-434 Sentence denotes Yet the biological significance of alpha(1-2) fucosylated structures is not well defined.
T4 435-569 Sentence denotes We have transfected a poorly tumorigenic rat colon carcinoma cell line with the human H blood group alpha(1-2)fucosyltransferase cDNA.
T5 570-707 Sentence denotes This resulted in cell surface expression of H antigens with a concomitant decrease of sialic acid substituted and free beta-galactosides.
T6 708-855 Sentence denotes Immunoprecipitation experiments showed that H antigens were essentially borne by variants of CD44 carrying amino acid sequences encoded by exon v6.
T7 856-973 Sentence denotes The transfected cells showed increased motility in a wound healing assay, without changing their proliferation rates.
T8 974-1137 Sentence denotes Parental and control cells transfected with an empty vector formed small tumors that always regressed after 30 days when injected subcutaneously to syngeneic rats.
T9 1138-1231 Sentence denotes In contrast, alpha(1-2)fucosyltransferase transfectants were able to form progressive tumors.
T10 1232-1287 Sentence denotes Increased tumorigenicity was also visible in nude mice.
T11 1288-1413 Sentence denotes These results demonstrate that alpha(1-2)fucosylated antigens contribute directly to aggressiveness of colon carcinoma cells.
T12 1414-1471 Sentence denotes This could occur by altering a function of CD44 variants.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-104 Sentence denotes Increase of rat colon carcinoma cells tumorigenicity by alpha(1-2) fucosyltransferase gene transfection.
T2 105-344 Sentence denotes Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens.
T3 345-434 Sentence denotes Yet the biological significance of alpha(1-2) fucosylated structures is not well defined.
T4 435-569 Sentence denotes We have transfected a poorly tumorigenic rat colon carcinoma cell line with the human H blood group alpha(1-2)fucosyltransferase cDNA.
T5 570-707 Sentence denotes This resulted in cell surface expression of H antigens with a concomitant decrease of sialic acid substituted and free beta-galactosides.
T6 708-855 Sentence denotes Immunoprecipitation experiments showed that H antigens were essentially borne by variants of CD44 carrying amino acid sequences encoded by exon v6.
T7 856-973 Sentence denotes The transfected cells showed increased motility in a wound healing assay, without changing their proliferation rates.
T8 974-1137 Sentence denotes Parental and control cells transfected with an empty vector formed small tumors that always regressed after 30 days when injected subcutaneously to syngeneic rats.
T9 1138-1231 Sentence denotes In contrast, alpha(1-2)fucosyltransferase transfectants were able to form progressive tumors.
T10 1232-1287 Sentence denotes Increased tumorigenicity was also visible in nude mice.
T11 1288-1413 Sentence denotes These results demonstrate that alpha(1-2)fucosylated antigens contribute directly to aggressiveness of colon carcinoma cells.
T12 1414-1471 Sentence denotes This could occur by altering a function of CD44 variants.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 152-159 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis b http://www.glycoepitope.jp/epitopes/EP0010
T2 161-168 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis Y http://www.glycoepitope.jp/epitopes/EP0018

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 16-31 Disease denotes colon carcinoma MONDO:0002032
T2 190-205 Disease denotes colon carcinoma MONDO:0002032
T3 480-495 Disease denotes colon carcinoma MONDO:0002032
T4 1391-1406 Disease denotes colon carcinoma MONDO:0002032

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 16-21 Body_part denotes colon FMA:14543
T2 123-128 Body_part denotes blood FMA:9670
T3 190-195 Body_part denotes colon FMA:14543
T4 480-485 Body_part denotes colon FMA:14543
T5 523-528 Body_part denotes blood FMA:9670
T6 587-599 Body_part denotes cell surface FMA:67653
T7 1391-1396 Body_part denotes colon FMA:14543

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 16-21 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T2 123-128 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000315
T3 190-195 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T4 480-485 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T5 523-528 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000315
T6 1391-1396 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 152-159 Glycan denotes Lewis b https://api.glycosmos.org/wurcs2image/latest/png/binary/G00048MO
T2 161-168 Glycan denotes Lewis Y https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 12-15 OrganismTaxon denotes rat 10114|10116
T3 476-479 OrganismTaxon denotes rat 10114|10116
T5 515-520 OrganismTaxon denotes human 9606
T6 1132-1136 OrganismTaxon denotes rats 10114|10116
T8 1282-1286 OrganismTaxon denotes mice 10088

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 16-21 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T2 123-128 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 190-195 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T4 480-485 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T5 523-528 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T6 1391-1396 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155