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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-244 Sentence denotes Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe preeclampsia.
TextSentencer_T2 245-256 Sentence denotes OBJECTIVES:
TextSentencer_T3 257-364 Sentence denotes Preeclampsia is characterized by maternal hypertension, proteinuria, edema, and shallow placental invasion.
TextSentencer_T4 365-505 Sentence denotes Insulin-like growth factor binding protein-1, abundant in maternal decidua, is believed to play a role in limiting trophoblast invasiveness.
TextSentencer_T5 506-614 Sentence denotes In this study we addressed the hypothesis that this binding protein is aberrantly expressed in preeclampsia.
TextSentencer_T6 615-781 Sentence denotes We also investigated circulating levels of insulin-like growth factor-I and insulin-like growth factor-II in subjects with severe preeclampsia compared with controls.
TextSentencer_T7 782-795 Sentence denotes STUDY DESIGN:
TextSentencer_T8 796-1024 Sentence denotes Insulin-like growth factor binding protein-1 was investigated by immunohistochemistry at the maternal-fetal interface of eight pregnancies complicated by severe preeclampsia and six controls between 21 and 34 weeks of gestation.
TextSentencer_T9 1025-1086 Sentence denotes Cell types were identified with use of cell-specific markers.
TextSentencer_T10 1087-1389 Sentence denotes Circulating levels of insulin-like growth factor binding protein-1, insulin-like growth factor-I, and insulin-like growth factor-II in 16 patients with severe preeclampsia and 29 controls at the same gestational age were determined by an immunoradiometric assay and correlated with clinical parameters.
TextSentencer_T11 1390-1440 Sentence denotes Data were analyzed by t test and Pearson's method.
TextSentencer_T12 1441-1449 Sentence denotes RESULTS:
TextSentencer_T13 1450-1611 Sentence denotes Insulin-like growth factor binding protein-1 was highly expressed on syncytiotrophoblasts, cytotrophoblasts, and decidual cells but not on placental fibroblasts.
TextSentencer_T14 1612-1726 Sentence denotes Immunostaining was greater at the maternal-fetal interface in severe preeclamptic patients compared with controls.
TextSentencer_T15 1727-1907 Sentence denotes Circulating insulin-like growth factor binding protein-1 levels in subjects with severe preeclampsia were 428.3 +/- 85.9 ng/ml compared with 76.6 +/- 11.8 in controls (p = 0.0007).
TextSentencer_T16 1908-2041 Sentence denotes Circulating insulin-like growth factor-I levels were 80.9 +/- 17.2 ng/ml compared with 179.4 +/- 28.2 ng/ml in controls (p = 0.0001).
TextSentencer_T17 2042-2143 Sentence denotes In contrast, insulin-like growth factor-II levels were not significantly different in the two groups.
TextSentencer_T18 2144-2345 Sentence denotes In subjects with severe preeclampsia insulin-like growth factor binding protein-1 levels correlated with diastolic blood pressure (r = 0.498, p 0.049) and aspartate transcarbamylase (0.621, p = 0.010).
TextSentencer_T19 2346-2358 Sentence denotes CONCLUSIONS:
TextSentencer_T20 2359-2620 Sentence denotes The abundance of insulin-like growth factor binding protein-1 at the maternal-fetal interface in severely preeclamptic pregnancies suggests that the binding protein may participate in the pathogenesis of the shallow placental invasion observed in this disorder.
TextSentencer_T21 2621-2797 Sentence denotes Low circulating insulin-like growth factor-I and elevated insulin-like growth factor binding protein-1 levels may contribute to restricted placental and therefore fetal growth.
T1 0-244 Sentence denotes Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe preeclampsia.
T2 245-256 Sentence denotes OBJECTIVES:
T3 257-364 Sentence denotes Preeclampsia is characterized by maternal hypertension, proteinuria, edema, and shallow placental invasion.
T4 365-505 Sentence denotes Insulin-like growth factor binding protein-1, abundant in maternal decidua, is believed to play a role in limiting trophoblast invasiveness.
T5 506-614 Sentence denotes In this study we addressed the hypothesis that this binding protein is aberrantly expressed in preeclampsia.
T6 615-781 Sentence denotes We also investigated circulating levels of insulin-like growth factor-I and insulin-like growth factor-II in subjects with severe preeclampsia compared with controls.
T7 782-795 Sentence denotes STUDY DESIGN:
T8 796-1024 Sentence denotes Insulin-like growth factor binding protein-1 was investigated by immunohistochemistry at the maternal-fetal interface of eight pregnancies complicated by severe preeclampsia and six controls between 21 and 34 weeks of gestation.
T9 1025-1086 Sentence denotes Cell types were identified with use of cell-specific markers.
T10 1087-1389 Sentence denotes Circulating levels of insulin-like growth factor binding protein-1, insulin-like growth factor-I, and insulin-like growth factor-II in 16 patients with severe preeclampsia and 29 controls at the same gestational age were determined by an immunoradiometric assay and correlated with clinical parameters.
T11 1390-1440 Sentence denotes Data were analyzed by t test and Pearson's method.
T12 1441-1449 Sentence denotes RESULTS:
T13 1450-1611 Sentence denotes Insulin-like growth factor binding protein-1 was highly expressed on syncytiotrophoblasts, cytotrophoblasts, and decidual cells but not on placental fibroblasts.
T14 1612-1726 Sentence denotes Immunostaining was greater at the maternal-fetal interface in severe preeclamptic patients compared with controls.
T15 1727-1907 Sentence denotes Circulating insulin-like growth factor binding protein-1 levels in subjects with severe preeclampsia were 428.3 +/- 85.9 ng/ml compared with 76.6 +/- 11.8 in controls (p = 0.0007).
T16 1908-2041 Sentence denotes Circulating insulin-like growth factor-I levels were 80.9 +/- 17.2 ng/ml compared with 179.4 +/- 28.2 ng/ml in controls (p = 0.0001).
T17 2042-2143 Sentence denotes In contrast, insulin-like growth factor-II levels were not significantly different in the two groups.
T18 2144-2345 Sentence denotes In subjects with severe preeclampsia insulin-like growth factor binding protein-1 levels correlated with diastolic blood pressure (r = 0.498, p 0.049) and aspartate transcarbamylase (0.621, p = 0.010).
T19 2346-2358 Sentence denotes CONCLUSIONS:
T20 2359-2620 Sentence denotes The abundance of insulin-like growth factor binding protein-1 at the maternal-fetal interface in severely preeclamptic pregnancies suggests that the binding protein may participate in the pathogenesis of the shallow placental invasion observed in this disorder.
T21 2621-2797 Sentence denotes Low circulating insulin-like growth factor-I and elevated insulin-like growth factor binding protein-1 levels may contribute to restricted placental and therefore fetal growth.

Preeclampsia

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 231-243 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 257-269 ORPHA:275555 denotes Preeclampsia
PD-Preeclampsia-B_T3 601-613 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T4 745-757 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T5 957-969 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T6 1246-1258 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T7 1681-1702 ORPHA:275555 denotes preeclamptic patients
PD-Preeclampsia-B_T8 1815-1827 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T9 2168-2180 ORPHA:275555 denotes preeclampsia

Preeclampsia-compare

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 231-243 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 257-269 ORPHA:275555 denotes Preeclampsia
PD-Preeclampsia-B_T3 601-613 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T4 745-757 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T5 957-969 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T6 1246-1258 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T7 1681-1693 ORPHA:275555 denotes preeclamptic
PD-Preeclampsia-B_T8 1815-1827 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T9 2168-2180 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T10 2465-2477 ORPHA:275555 denotes preeclamptic

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 432-439 http://purl.obolibrary.org/obo/UBERON_0002450 denotes decidua
PD-UBERON-AE-B_T2 480-491 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T3 1519-1539 http://purl.obolibrary.org/obo/UBERON_0000371 denotes syncytiotrophoblasts
PD-UBERON-AE-B_T4 1541-1557 http://purl.obolibrary.org/obo/UBERON_0000319 denotes cytotrophoblasts
PD-UBERON-AE-B_T5 2259-2264 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

preeclampsia_genes

Id Subject Object Predicate Lexical cue
PD-PreeclampsiaGenes-B_T1 0-7 HGNC:INS denotes Insulin
PD-PreeclampsiaGenes-B_T2 81-88 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T3 111-118 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T4 146-153 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T5 365-372 HGNC:INS denotes Insulin
PD-PreeclampsiaGenes-B_T6 658-665 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T7 691-698 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T8 796-803 HGNC:INS denotes Insulin
PD-PreeclampsiaGenes-B_T9 1109-1116 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T10 1155-1162 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T11 1189-1196 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T12 1450-1457 HGNC:INS denotes Insulin
PD-PreeclampsiaGenes-B_T13 1739-1746 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T14 1920-1927 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T15 2055-2062 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T16 2181-2188 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T17 2376-2383 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T18 2637-2644 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T19 2679-2686 HGNC:INS denotes insulin
PD-PreeclampsiaGenes-B_T20 0-26 HGNC:IGF2 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T21 81-107 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T22 111-137 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T23 146-172 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T24 365-391 HGNC:IGF2 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T25 658-684 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T26 691-717 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T27 796-822 HGNC:IGF2 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T28 1109-1135 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T29 1155-1181 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T30 1189-1215 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T31 1450-1476 HGNC:IGF2 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T32 1739-1765 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T33 1920-1946 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T34 2055-2081 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T35 2181-2207 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T36 2376-2402 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T37 2637-2663 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T38 2679-2705 HGNC:IGF2 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T39 0-26 HGNC:IGF1 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T40 81-107 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T41 111-137 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T42 146-172 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T43 365-391 HGNC:IGF1 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T44 658-684 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T45 691-717 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T46 796-822 HGNC:IGF1 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T47 1109-1135 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T48 1155-1181 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T49 1189-1215 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T50 1450-1476 HGNC:IGF1 denotes Insulin-like growth factor
PD-PreeclampsiaGenes-B_T51 1739-1765 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T52 1920-1946 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T53 2055-2081 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T54 2181-2207 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T55 2376-2402 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T56 2637-2663 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T57 2679-2705 HGNC:IGF1 denotes insulin-like growth factor
PD-PreeclampsiaGenes-B_T58 0-42 HGNC:IGFBP7 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T59 146-188 HGNC:IGFBP7 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T60 365-407 HGNC:IGFBP7 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T61 796-838 HGNC:IGFBP7 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T62 1109-1151 HGNC:IGFBP7 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T63 1450-1492 HGNC:IGFBP7 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T64 1739-1781 HGNC:IGFBP7 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T65 2181-2223 HGNC:IGFBP7 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T66 2376-2418 HGNC:IGFBP7 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T67 2679-2721 HGNC:IGFBP7 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T68 0-42 HGNC:IGFBP3 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T69 146-188 HGNC:IGFBP3 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T70 365-407 HGNC:IGFBP3 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T71 796-838 HGNC:IGFBP3 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T72 1109-1151 HGNC:IGFBP3 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T73 1450-1492 HGNC:IGFBP3 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T74 1739-1781 HGNC:IGFBP3 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T75 2181-2223 HGNC:IGFBP3 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T76 2376-2418 HGNC:IGFBP3 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T77 2679-2721 HGNC:IGFBP3 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T78 0-42 HGNC:IGFBP2 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T79 146-188 HGNC:IGFBP2 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T80 365-407 HGNC:IGFBP2 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T81 796-838 HGNC:IGFBP2 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T82 1109-1151 HGNC:IGFBP2 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T83 1450-1492 HGNC:IGFBP2 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T84 1739-1781 HGNC:IGFBP2 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T85 2181-2223 HGNC:IGFBP2 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T86 2376-2418 HGNC:IGFBP2 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T87 2679-2721 HGNC:IGFBP2 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T88 0-42 HGNC:IGFBP4 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T89 146-188 HGNC:IGFBP4 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T90 365-407 HGNC:IGFBP4 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T91 796-838 HGNC:IGFBP4 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T92 1109-1151 HGNC:IGFBP4 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T93 1450-1492 HGNC:IGFBP4 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T94 1739-1781 HGNC:IGFBP4 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T95 2181-2223 HGNC:IGFBP4 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T96 2376-2418 HGNC:IGFBP4 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T97 2679-2721 HGNC:IGFBP4 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T98 0-42 HGNC:IGFBP5 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T99 146-188 HGNC:IGFBP5 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T100 365-407 HGNC:IGFBP5 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T101 796-838 HGNC:IGFBP5 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T102 1109-1151 HGNC:IGFBP5 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T103 1450-1492 HGNC:IGFBP5 denotes Insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T104 1739-1781 HGNC:IGFBP5 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T105 2181-2223 HGNC:IGFBP5 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T106 2376-2418 HGNC:IGFBP5 denotes insulin-like growth factor binding protein
PD-PreeclampsiaGenes-B_T107 2679-2721 HGNC:IGFBP5 denotes insulin-like growth factor binding protein

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 2259-2264 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 345-354 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental
PD-UBERON-AE-B_T3 1589-1598 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental
PD-UBERON-AE-B_T4 2575-2584 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental
PD-UBERON-AE-B_T5 2760-2769 http://purl.obolibrary.org/obo/UBERON_0001987 denotes placental
PD-UBERON-AE-B_T6 480-491 http://purl.obolibrary.org/obo/UBERON_0000088 denotes trophoblast
PD-UBERON-AE-B_T7 432-439 http://purl.obolibrary.org/obo/UBERON_0002450 denotes decidua
PD-UBERON-AE-B_T8 1519-1539 http://purl.obolibrary.org/obo/UBERON_0000371 denotes syncytiotrophoblasts
PD-UBERON-AE-B_T9 1541-1557 http://purl.obolibrary.org/obo/UBERON_0000319 denotes cytotrophoblasts