PubMed:9106500
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 112-118 | Cell | denotes | T-cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T2 | 261-271 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T3 | 276-283 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T4 | 312-322 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T5 | 1125-1135 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T6 | 1153-1160 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T7 | 1171-1181 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T8 | 1461-1468 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T9 | 1534-1544 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T10 | 1561-1571 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T11 | 1597-1604 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T12 | 1669-1679 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T13 | 1691-1698 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T14 | 1782-1792 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 414-418 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T2 | 420-424 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T3 | 769-773 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T4 | 881-885 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T5 | 935-939 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T6 | 1708-1712 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 414-418 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T2 | 420-424 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T3 | 646-649 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T4 | 769-773 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T5 | 881-885 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T6 | 935-939 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T7 | 1065-1068 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T8 | 1293-1296 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T9 | 1423-1426 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T10 | 1708-1712 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 39-42 | OrganismTaxon | denotes | rat | 10114|10116 |
| T3 | 257-260 | OrganismTaxon | denotes | rat | 10114|10116 |
| T5 | 676-680 | OrganismTaxon | denotes | mice | 10088 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 112-118 | Cell | denotes | T-cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T2 | 261-271 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T3 | 276-283 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T4 | 312-322 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T5 | 1125-1135 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T6 | 1153-1160 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T7 | 1171-1181 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T8 | 1461-1468 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T9 | 1534-1544 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T10 | 1561-1571 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T11 | 1597-1604 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T12 | 1669-1679 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
| T13 | 1691-1698 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T14 | 1782-1792 | Cell | denotes | thymocytes | http://purl.obolibrary.org/obo/CL:0000893 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 112-118 | Body_part | denotes | T-cell | http://purl.obolibrary.org/obo/CL_0000084 |
| T2 | 261-271 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T3 | 312-322 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T4 | 1125-1135 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T5 | 1171-1181 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T6 | 1534-1544 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T7 | 1561-1571 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T8 | 1669-1679 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T9 | 1782-1792 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-59 | Sentence | denotes | Gangliosides involved in activation of rat T lineage cells. |
| T2 | 60-130 | Sentence | denotes | Gangliosides have long been known to be involved in T-cell activation. |
| T3 | 131-284 | Sentence | denotes | In our previous studies, a unique GMlb-derived ganglioside, GD1c(NeuGc,NeuGc), was shown to be the predominant ganglioside in rat thymocytes and T-cells. |
| T4 | 285-534 | Sentence | denotes | Upon the activation of the thymocytes, the amount of GD1c(NeuGc,NeuGc) increases remarkably, and additionally a novel species of GD1b, GD1b(NeuGc,NeuGc), appears as the other major ganglioside (Nohara, et al. (1993) J. Biol. Chem. 268, 24997-25000). |
| T5 | 535-637 | Sentence | denotes | In the present study, monoclonal antibodies (MAbs) against these two gangliosides have been generated. |
| T6 | 638-832 | Sentence | denotes | The MAb AC1 established by immunizing mice with purified GD1c(NeuGc,NeuGc) reacted strongly with GD1c(NeuGc,NeuGc) and weakly with GD1b(NeuGc,NeuGc) by enzyme-linked immunosorbent assay (ELISA). |
| T7 | 833-1001 | Sentence | denotes | The other MAb AB1 obtained by immunization with GD1b(NeuGc,NeuGc) showed a strong binding activity to GD1b(NeuGc,NeuGc) and no reactivity to GDlc(NeuGc,NeuGc) by ELISA. |
| T8 | 1002-1161 | Sentence | denotes | Flow cytometry analyses using these MAbs have revealed that an AC1-positive subset exists in a portion of resting CD4+CD8- thymocytes and CD4+ splenic T-cells. |
| T9 | 1162-1389 | Sentence | denotes | When the thymocytes were activated with 12-O-tetradecanoylpholbol-13-acetate (TPA) and calcium ionophore A23187, the proportion of AC1+ cells increased remarkably and were detected not only in CD4+ cells but also in CD8+ cells. |
| T10 | 1390-1469 | Sentence | denotes | An increase in the proportion of AC1+ cells was also seen in activated T-cells. |
| T11 | 1470-1605 | Sentence | denotes | In contrast, AB1-positive cells were only detected in activated thymocytes, not in resting thymocytes, or resting or activated T-cells. |
| T12 | 1606-1793 | Sentence | denotes | These results implicate GD1c(NeuGc,NeuGc) in the activation of thymocytes as well as T-cells, whereas GD1b(NeuGc,NeuGc) appears to be specifically related to the activation of thymocytes. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 414-418 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T2 | 420-424 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T3 | 769-773 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T4 | 881-885 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T5 | 935-939 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
| T6 | 1708-1712 | Glycan | denotes | GD1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G37184KW |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 414-418 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T2 | 420-424 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T3 | 646-649 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T4 | 769-773 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T5 | 881-885 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T6 | 935-939 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
| T7 | 1065-1068 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T8 | 1293-1296 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T9 | 1423-1426 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | AC1 | http://www.glycoepitope.jp/epitopes/AN0202 |
| T10 | 1708-1712 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GD1b | http://www.glycoepitope.jp/epitopes/EP0059 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 39-42 | OrganismTaxon | denotes | rat | 10114|10116 |
| T3 | 257-260 | OrganismTaxon | denotes | rat | 10114|10116 |
| T5 | 676-680 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 112-118 | Body_part | denotes | T-cell | http://purl.obolibrary.org/obo/CL_0000084 |
| T2 | 261-271 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T3 | 312-322 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T4 | 1125-1135 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T5 | 1171-1181 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T6 | 1534-1544 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T7 | 1561-1571 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T8 | 1669-1679 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |
| T9 | 1782-1792 | Body_part | denotes | thymocytes | http://purl.obolibrary.org/obo/CL_0000893 |