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PubMed:9061365 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 297-313 https://glytoucan.org/Structures/Glycans/G20420WT denotes lactosylceramide
T2 297-313 https://glytoucan.org/Structures/Glycans/G74621DY denotes lactosylceramide
T3 297-313 https://glytoucan.org/Structures/Glycans/G84224TW denotes lactosylceramide
T4 327-343 https://glytoucan.org/Structures/Glycans/G71142DF denotes glucosylceramide
T5 885-894 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T6 885-894 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T7 1434-1450 https://glytoucan.org/Structures/Glycans/G20420WT denotes lactosylceramide
T8 1434-1450 https://glytoucan.org/Structures/Glycans/G74621DY denotes lactosylceramide
T9 1434-1450 https://glytoucan.org/Structures/Glycans/G84224TW denotes lactosylceramide

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 297-313 Glycan_Motif denotes lactosylceramide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G74621DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G20420WT
T4 315-321 Glycan_Motif denotes LacCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW
T5 327-343 Glycan_Motif denotes glucosylceramide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T6 345-351 Glycan_Motif denotes GlcCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T7 432-438 Glycan_Motif denotes GlcCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T8 473-479 Glycan_Motif denotes GlcCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T9 633-639 Glycan_Motif denotes LacCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW
T10 737-743 Glycan_Motif denotes GlcCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T11 885-894 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T13 896-902 Glycan_Motif denotes GlcCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T14 1014-1020 Glycan_Motif denotes LacCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW
T15 1030-1036 Glycan_Motif denotes GlcCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G71142DF
T16 1246-1252 Glycan_Motif denotes LacCer https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW
T17 1434-1450 Glycan_Motif denotes lactosylceramide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G84224TW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G74621DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G20420WT

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 82-87 http://purl.obolibrary.org/obo/MAT_0000035 denotes aorta
T2 375-388 http://purl.obolibrary.org/obo/MAT_0000303 denotes smooth muscle
T3 382-388 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle
T4 1143-1156 http://purl.obolibrary.org/obo/MAT_0000303 denotes smooth muscle
T5 1150-1156 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle
T6 1503-1516 http://purl.obolibrary.org/obo/MAT_0000303 denotes smooth muscle
T7 1510-1516 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-96 Sentence denotes Accumulation of glycosphingolipids in human atherosclerotic plaque and unaffected aorta tissues.
TextSentencer_T2 97-281 Sentence denotes We have measured the levels of glycosphingolipids and the activity of glycosphingolipid glycosyltransferases in human aortic intima and media from patients who died of atherosclerosis.
TextSentencer_T3 282-422 Sentence denotes The effects of lactosylceramide (LacCer) and glucosylceramide (GlcCer) from plaque intima on smooth muscle cell proliferation were assessed.
TextSentencer_T4 423-608 Sentence denotes When the GlcCer data was expressed as (micrograms GlcCer/mg cholesterol and/mg total phospholipid, a 28-fold and 7-fold increase in plaque intima compared to normal intima was observed.
TextSentencer_T5 609-716 Sentence denotes Similarly, the level of LacCer was elevated 5-fold and 4-fold, respectively, compared to unaffected intima.
TextSentencer_T6 717-855 Sentence denotes The activity of UDP-GlcCer: ceramide beta 1-->4 glucosyltransferase (GlcT-1) was similar in unaffected tissue, fatty streaks, and plaques.
TextSentencer_T7 856-895 Sentence denotes However, the activity of UDP-galactose:
TextSentencer_T8 896-1013 Sentence denotes GlcCer, beta 1-->4 galactosyltransferase (GalT-2) activity was moderately higher in plaque than in unaffected tissue.
TextSentencer_T9 1014-1355 Sentence denotes LacCer, but not GlcCer derived from plaque intima exerted a approximately 2.8-fold increase in the proliferation of human aortic smooth muscle cells grown in tissue culture compared to control presumably due to a marked increase in LacCer molecular species containing C16:0, C22:1, and C24:0 fatty acids in plaque intima compared to control.
TextSentencer_T10 1356-1536 Sentence denotes In sum, our findings provide an interesting and novel pathogenic mechanism of lactosylceramide mediated plaque formation via stimulation of aortic smooth muscle cell proliferation.
T1 0-96 Sentence denotes Accumulation of glycosphingolipids in human atherosclerotic plaque and unaffected aorta tissues.
T2 97-281 Sentence denotes We have measured the levels of glycosphingolipids and the activity of glycosphingolipid glycosyltransferases in human aortic intima and media from patients who died of atherosclerosis.
T3 282-422 Sentence denotes The effects of lactosylceramide (LacCer) and glucosylceramide (GlcCer) from plaque intima on smooth muscle cell proliferation were assessed.
T4 423-608 Sentence denotes When the GlcCer data was expressed as (micrograms GlcCer/mg cholesterol and/mg total phospholipid, a 28-fold and 7-fold increase in plaque intima compared to normal intima was observed.
T5 609-716 Sentence denotes Similarly, the level of LacCer was elevated 5-fold and 4-fold, respectively, compared to unaffected intima.
T6 717-855 Sentence denotes The activity of UDP-GlcCer: ceramide beta 1-->4 glucosyltransferase (GlcT-1) was similar in unaffected tissue, fatty streaks, and plaques.
T7 856-895 Sentence denotes However, the activity of UDP-galactose:
T8 896-1013 Sentence denotes GlcCer, beta 1-->4 galactosyltransferase (GalT-2) activity was moderately higher in plaque than in unaffected tissue.
T9 1014-1355 Sentence denotes LacCer, but not GlcCer derived from plaque intima exerted a approximately 2.8-fold increase in the proliferation of human aortic smooth muscle cells grown in tissue culture compared to control presumably due to a marked increase in LacCer molecular species containing C16:0, C22:1, and C24:0 fatty acids in plaque intima compared to control.
T10 1356-1536 Sentence denotes In sum, our findings provide an interesting and novel pathogenic mechanism of lactosylceramide mediated plaque formation via stimulation of aortic smooth muscle cell proliferation.
T1 0-96 Sentence denotes Accumulation of glycosphingolipids in human atherosclerotic plaque and unaffected aorta tissues.
T2 97-281 Sentence denotes We have measured the levels of glycosphingolipids and the activity of glycosphingolipid glycosyltransferases in human aortic intima and media from patients who died of atherosclerosis.
T3 282-422 Sentence denotes The effects of lactosylceramide (LacCer) and glucosylceramide (GlcCer) from plaque intima on smooth muscle cell proliferation were assessed.
T4 423-608 Sentence denotes When the GlcCer data was expressed as (micrograms GlcCer/mg cholesterol and/mg total phospholipid, a 28-fold and 7-fold increase in plaque intima compared to normal intima was observed.
T5 609-716 Sentence denotes Similarly, the level of LacCer was elevated 5-fold and 4-fold, respectively, compared to unaffected intima.
T6 717-855 Sentence denotes The activity of UDP-GlcCer: ceramide beta 1-->4 glucosyltransferase (GlcT-1) was similar in unaffected tissue, fatty streaks, and plaques.
T7 856-895 Sentence denotes However, the activity of UDP-galactose:
T8 896-1013 Sentence denotes GlcCer, beta 1-->4 galactosyltransferase (GalT-2) activity was moderately higher in plaque than in unaffected tissue.
T9 1014-1355 Sentence denotes LacCer, but not GlcCer derived from plaque intima exerted a approximately 2.8-fold increase in the proliferation of human aortic smooth muscle cells grown in tissue culture compared to control presumably due to a marked increase in LacCer molecular species containing C16:0, C22:1, and C24:0 fatty acids in plaque intima compared to control.
T10 1356-1536 Sentence denotes In sum, our findings provide an interesting and novel pathogenic mechanism of lactosylceramide mediated plaque formation via stimulation of aortic smooth muscle cell proliferation.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 297-313 https://glytoucan.org/Structures/Glycans/G20420WT denotes lactosylceramide
T2 297-313 https://glytoucan.org/Structures/Glycans/G74621DY denotes lactosylceramide
T3 297-313 https://glytoucan.org/Structures/Glycans/G84224TW denotes lactosylceramide
T4 327-343 https://glytoucan.org/Structures/Glycans/G71142DF denotes glucosylceramide
T5 885-894 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T6 885-894 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose
T7 1434-1450 https://glytoucan.org/Structures/Glycans/G20420WT denotes lactosylceramide
T8 1434-1450 https://glytoucan.org/Structures/Glycans/G74621DY denotes lactosylceramide
T9 1434-1450 https://glytoucan.org/Structures/Glycans/G84224TW denotes lactosylceramide

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 297-313 http://www.glycoepitope.jp/epitopes/EP0078 denotes lactosylceramide
T2 315-321 http://www.glycoepitope.jp/epitopes/EP0078 denotes LacCer
T3 633-639 http://www.glycoepitope.jp/epitopes/EP0078 denotes LacCer
T4 1014-1020 http://www.glycoepitope.jp/epitopes/EP0078 denotes LacCer
T5 1246-1252 http://www.glycoepitope.jp/epitopes/EP0078 denotes LacCer
T6 1434-1450 http://www.glycoepitope.jp/epitopes/EP0078 denotes lactosylceramide

GlycoBiology-cGGDB

Id Subject Object Predicate Lexical cue
_T1 786-792 http://jcggdb.jp/cggdb/entry.action?jcg_id=JCEG092 denotes GlcT-1

ICD10

Id Subject Object Predicate Lexical cue
T1 265-280 http://purl.bioontology.org/ontology/ICD10/I70 denotes atherosclerosis

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 16-34 FMAID:196810 denotes glycosphingolipids
_T2 16-34 FMAID:82815 denotes glycosphingolipids
_T3 16-34 FMAID:82812 denotes glycosphingolipids
_T4 16-34 FMAID:196807 denotes glycosphingolipids
_T5 16-34 FMAID:82817 denotes glycosphingolipids
_T6 16-34 FMAID:196812 denotes glycosphingolipids
_T7 16-34 FMAID:82814 denotes glycosphingolipids
_T8 16-34 FMAID:196809 denotes glycosphingolipids
_T9 16-34 FMAID:82819 denotes glycosphingolipids
_T10 16-34 FMAID:196815 denotes glycosphingolipids
_T11 16-34 FMAID:196808 denotes glycosphingolipids
_T12 16-34 FMAID:82813 denotes glycosphingolipids
_T13 16-34 FMAID:196806 denotes glycosphingolipids
_T14 16-34 FMAID:82811 denotes glycosphingolipids
_T15 16-34 FMAID:82818 denotes glycosphingolipids
_T16 16-34 FMAID:196813 denotes glycosphingolipids
_T17 16-34 FMAID:196814 denotes glycosphingolipids
_T18 82-87 FMAID:90119 denotes aorta
_T19 82-87 FMAID:3734 denotes aorta
_T20 88-95 FMAID:256050 denotes tissues
_T21 128-146 FMAID:196815 denotes glycosphingolipids
_T22 128-146 FMAID:82812 denotes glycosphingolipids
_T23 128-146 FMAID:196813 denotes glycosphingolipids
_T24 128-146 FMAID:82818 denotes glycosphingolipids
_T25 128-146 FMAID:82811 denotes glycosphingolipids
_T26 128-146 FMAID:196806 denotes glycosphingolipids
_T27 128-146 FMAID:196808 denotes glycosphingolipids
_T28 128-146 FMAID:196807 denotes glycosphingolipids
_T29 128-146 FMAID:82813 denotes glycosphingolipids
_T30 128-146 FMAID:82815 denotes glycosphingolipids
_T31 128-146 FMAID:196810 denotes glycosphingolipids
_T32 128-146 FMAID:196812 denotes glycosphingolipids
_T33 128-146 FMAID:196814 denotes glycosphingolipids
_T34 128-146 FMAID:196809 denotes glycosphingolipids
_T35 128-146 FMAID:82819 denotes glycosphingolipids
_T36 128-146 FMAID:82817 denotes glycosphingolipids
_T37 128-146 FMAID:82814 denotes glycosphingolipids
_T38 167-184 FMAID:196806 denotes glycosphingolipid
_T39 167-184 FMAID:82814 denotes glycosphingolipid
_T40 167-184 FMAID:196810 denotes glycosphingolipid
_T41 167-184 FMAID:82815 denotes glycosphingolipid
_T42 167-184 FMAID:196809 denotes glycosphingolipid
_T43 167-184 FMAID:196814 denotes glycosphingolipid
_T44 167-184 FMAID:82817 denotes glycosphingolipid
_T45 167-184 FMAID:196812 denotes glycosphingolipid
_T46 167-184 FMAID:196808 denotes glycosphingolipid
_T47 167-184 FMAID:82819 denotes glycosphingolipid
_T48 167-184 FMAID:196813 denotes glycosphingolipid
_T49 167-184 FMAID:82818 denotes glycosphingolipid
_T50 167-184 FMAID:196807 denotes glycosphingolipid
_T51 167-184 FMAID:82812 denotes glycosphingolipid
_T52 167-184 FMAID:82811 denotes glycosphingolipid
_T53 167-184 FMAID:196815 denotes glycosphingolipid
_T54 167-184 FMAID:82813 denotes glycosphingolipid
_T55 297-313 FMAID:82821 denotes lactosylceramide
_T56 297-313 FMAID:196817 denotes lactosylceramide
_T57 327-343 FMAID:82820 denotes glucosylceramide
_T58 327-343 FMAID:196816 denotes glucosylceramide
_T59 345-351 FMAID:196821 denotes GlcCer
_T60 375-393 FMAID:226205 denotes smooth muscle cell
_T61 375-393 FMAID:260654 denotes smooth muscle cell
_T62 375-393 FMAID:260655 denotes smooth muscle cell
_T63 375-393 FMAID:226206 denotes smooth muscle cell
_T64 375-393 FMAID:201944 denotes smooth muscle cell
_T65 375-393 FMAID:14072 denotes smooth muscle cell
_T66 375-393 FMAID:103614 denotes smooth muscle cell
_T67 382-388 FMAID:123535 denotes muscle
_T68 382-388 FMAID:30316 denotes muscle
_T69 382-388 FMAID:172175 denotes muscle
_T70 382-393 FMAID:67328 denotes muscle cell
_T71 382-393 FMAID:201709 denotes muscle cell
_T72 382-393 FMAID:86767 denotes muscle cell
_T73 382-393 FMAID:165278 denotes muscle cell
_T74 432-438 FMAID:196821 denotes GlcCer
_T75 473-479 FMAID:196821 denotes GlcCer
_T76 508-520 FMAID:196772 denotes phospholipid
_T77 508-520 FMAID:82779 denotes phospholipid
_T78 737-743 FMAID:196821 denotes GlcCer
_T79 820-826 FMAID:256050 denotes tissue
_T80 885-894 FMAID:82794 denotes galactose
_T81 885-894 FMAID:196789 denotes galactose
_T82 896-902 FMAID:196821 denotes GlcCer
_T83 938-942 FMAID:265385 denotes GalT
_T84 1006-1012 FMAID:256050 denotes tissue
_T85 1030-1036 FMAID:196821 denotes GlcCer
_T86 1143-1162 FMAID:226206 denotes smooth muscle cells
_T87 1143-1162 FMAID:201944 denotes smooth muscle cells
_T88 1143-1162 FMAID:260654 denotes smooth muscle cells
_T89 1143-1162 FMAID:103614 denotes smooth muscle cells
_T90 1143-1162 FMAID:14072 denotes smooth muscle cells
_T91 1143-1162 FMAID:226205 denotes smooth muscle cells
_T92 1143-1162 FMAID:260655 denotes smooth muscle cells
_T93 1150-1156 FMAID:30316 denotes muscle
_T94 1150-1156 FMAID:123535 denotes muscle
_T95 1150-1156 FMAID:172175 denotes muscle
_T96 1150-1162 FMAID:67328 denotes muscle cells
_T97 1150-1162 FMAID:165278 denotes muscle cells
_T98 1150-1162 FMAID:86767 denotes muscle cells
_T99 1150-1162 FMAID:201709 denotes muscle cells
_T100 1157-1162 FMAID:68646 denotes cells
_T101 1157-1162 FMAID:169002 denotes cells
_T102 1172-1178 FMAID:256050 denotes tissue
_T103 1306-1317 FMAID:82738 denotes fatty acids
_T104 1306-1317 FMAID:196726 denotes fatty acids
_T105 1434-1450 FMAID:82821 denotes lactosylceramide
_T106 1434-1450 FMAID:196817 denotes lactosylceramide
_T107 1503-1521 FMAID:103614 denotes smooth muscle cell
_T108 1503-1521 FMAID:201944 denotes smooth muscle cell
_T109 1503-1521 FMAID:226205 denotes smooth muscle cell
_T110 1503-1521 FMAID:226206 denotes smooth muscle cell
_T111 1503-1521 FMAID:260654 denotes smooth muscle cell
_T112 1503-1521 FMAID:14072 denotes smooth muscle cell
_T113 1503-1521 FMAID:260655 denotes smooth muscle cell
_T114 1510-1516 FMAID:172175 denotes muscle
_T115 1510-1516 FMAID:123535 denotes muscle
_T116 1510-1516 FMAID:30316 denotes muscle
_T117 1510-1521 FMAID:67328 denotes muscle cell
_T118 1510-1521 FMAID:86767 denotes muscle cell
_T119 1510-1521 FMAID:201709 denotes muscle cell
_T120 1510-1521 FMAID:165278 denotes muscle cell

uniprot-human

Id Subject Object Predicate Lexical cue
T1 754-760 http://www.uniprot.org/uniprot/Q92988 denotes beta 1
T2 904-910 http://www.uniprot.org/uniprot/Q92988 denotes beta 1
T3 1289-1292 http://www.uniprot.org/uniprot/O00468 denotes C22

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 915-936 http://www.uniprot.org/uniprot/P23336 denotes galactosyltransferase
T2 1289-1292 http://www.uniprot.org/uniprot/A2ASQ1 denotes C22
T3 1289-1292 http://www.uniprot.org/uniprot/Q8VI67 denotes C22

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 88-95 http://purl.bioontology.org/ontology/STY/T024 denotes tissues
T2 754-758 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T3 754-758 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T4 820-826 http://purl.bioontology.org/ontology/STY/T024 denotes tissue
T5 904-908 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T6 904-908 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T7 1006-1012 http://purl.bioontology.org/ontology/STY/T024 denotes tissue
T8 1157-1162 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T9 1172-1178 http://purl.bioontology.org/ontology/STY/T024 denotes tissue
T10 1368-1376 http://purl.bioontology.org/ontology/STY/T033 denotes findings
T11 1421-1430 http://purl.bioontology.org/ontology/NCBITAXON/127244 denotes mechanism

GO-BP

Id Subject Object Predicate Lexical cue
T1 375-393 http://purl.obolibrary.org/obo/GO_0034390 denotes smooth muscle cell
T2 1143-1162 http://purl.obolibrary.org/obo/GO_0034390 denotes smooth muscle cells
T3 375-393 http://purl.obolibrary.org/obo/GO_0014909 denotes smooth muscle cell
T4 1143-1162 http://purl.obolibrary.org/obo/GO_0014909 denotes smooth muscle cells
T5 375-393 http://purl.obolibrary.org/obo/GO_0071670 denotes smooth muscle cell
T6 1143-1162 http://purl.obolibrary.org/obo/GO_0071670 denotes smooth muscle cells
T7 375-393 http://purl.obolibrary.org/obo/GO_0048659 denotes smooth muscle cell
T8 375-407 http://purl.obolibrary.org/obo/GO_0048659 denotes smooth muscle cell proliferation
T9 1503-1535 http://purl.obolibrary.org/obo/GO_0048659 denotes smooth muscle cell proliferation
T10 375-393 http://purl.obolibrary.org/obo/GO_0051145 denotes smooth muscle cell
T11 1143-1162 http://purl.obolibrary.org/obo/GO_0051145 denotes smooth muscle cells
T12 375-407 http://purl.obolibrary.org/obo/GO_0048662 denotes smooth muscle cell proliferation
T13 1503-1535 http://purl.obolibrary.org/obo/GO_0048662 denotes smooth muscle cell proliferation
T14 375-407 http://purl.obolibrary.org/obo/GO_0048661 denotes smooth muscle cell proliferation
T15 1503-1535 http://purl.obolibrary.org/obo/GO_0048661 denotes smooth muscle cell proliferation
T16 375-407 http://purl.obolibrary.org/obo/GO_0048660 denotes smooth muscle cell proliferation
T17 1503-1535 http://purl.obolibrary.org/obo/GO_0048660 denotes smooth muscle cell proliferation
T18 375-407 http://purl.obolibrary.org/obo/GO_1990874 denotes smooth muscle cell proliferation
T19 1503-1535 http://purl.obolibrary.org/obo/GO_1990874 denotes smooth muscle cell proliferation
T20 382-407 http://purl.obolibrary.org/obo/GO_0014855 denotes muscle cell proliferation
T21 1510-1535 http://purl.obolibrary.org/obo/GO_0014855 denotes muscle cell proliferation
T22 382-407 http://purl.obolibrary.org/obo/GO_0060038 denotes muscle cell proliferation
T23 1510-1535 http://purl.obolibrary.org/obo/GO_0060038 denotes muscle cell proliferation
T24 382-407 http://purl.obolibrary.org/obo/GO_0014856 denotes muscle cell proliferation
T25 1510-1535 http://purl.obolibrary.org/obo/GO_0014856 denotes muscle cell proliferation
T26 389-407 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T27 1517-1535 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T28 1467-1476 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T29 1496-1521 http://purl.obolibrary.org/obo/GO_0035887 denotes aortic smooth muscle cell

GO-CC

Id Subject Object Predicate Lexical cue
T1 389-393 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 1157-1162 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 82-87 http://purl.obolibrary.org/obo/UBERON_0000947 denotes aorta
T2 88-95 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
T3 820-826 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
T4 1006-1012 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
T5 1172-1178 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 82-87 http://purl.obolibrary.org/obo/MAT_0000035 denotes aorta
T2 375-388 http://purl.obolibrary.org/obo/MAT_0000303 denotes smooth muscle
T3 382-388 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle
T4 1143-1156 http://purl.obolibrary.org/obo/MAT_0000303 denotes smooth muscle
T5 1150-1156 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle
T6 1503-1516 http://purl.obolibrary.org/obo/MAT_0000303 denotes smooth muscle
T7 1510-1516 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 1282-1285 https://acgg.asia/db/lfdb/LfDB0050 denotes C16

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 297-313 http://www.glycoepitope.jp/epitopes/EP0078 denotes lactosylceramide
PD-GlycoEpitope-B_T2 1434-1450 http://www.glycoepitope.jp/epitopes/EP0078 denotes lactosylceramide
PD-GlycoEpitope-B_T3 524-526 http://www.glycoepitope.jp/epitopes/AN0746 denotes 28

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 88-95 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 820-826 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T3 1006-1012 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T4 1172-1178 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T5 82-87 http://purl.obolibrary.org/obo/UBERON_0000947 denotes aorta

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 265-280 Disease denotes atherosclerosis http://purl.obolibrary.org/obo/MONDO_0005311

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 82-87 Body_part denotes aorta http://purl.obolibrary.org/obo/MAT_0000035
T2 375-388 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303
T3 1143-1156 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303
T4 1503-1516 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 265-280 Phenotype denotes atherosclerosis HP:0002621
T2 828-841 Phenotype denotes fatty streaks HP:0031011

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 297-313 Glycan denotes lactosylceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T2 315-321 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T3 633-639 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T4 1014-1020 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T5 1246-1252 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T6 1434-1450 Glycan denotes lactosylceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 265-280 Phenotype denotes atherosclerosis HP:0002621
T2 828-841 Phenotype denotes fatty streaks HP:0031011

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 265-280 Disease denotes atherosclerosis MONDO:0005311

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 375-393 Cell denotes smooth muscle cell http://purl.obolibrary.org/obo/CL:0000192
T2 382-393 Cell denotes muscle cell http://purl.obolibrary.org/obo/CL:0000187
T3 1136-1162 Cell denotes aortic smooth muscle cells http://purl.obolibrary.org/obo/CL:0002539
T4 1143-1162 Cell denotes smooth muscle cells http://purl.obolibrary.org/obo/CL:0000192
T5 1496-1521 Cell denotes aortic smooth muscle cell http://purl.obolibrary.org/obo/CL:0002539
T6 1503-1521 Cell denotes smooth muscle cell http://purl.obolibrary.org/obo/CL:0000192
T7 1510-1521 Cell denotes muscle cell http://purl.obolibrary.org/obo/CL:0000187

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 60-66 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T2 82-87 Body_part denotes aorta http://purl.obolibrary.org/obo/UBERON_0000947
T3 222-228 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T4 358-364 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T5 365-371 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T6 375-393 Body_part denotes smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192
T7 555-561 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T8 562-568 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T9 588-594 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T10 709-715 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T11 820-826 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T12 980-986 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T13 1006-1012 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T14 1050-1056 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T15 1057-1063 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T16 1136-1162 Body_part denotes aortic smooth muscle cells http://purl.obolibrary.org/obo/CL_0002539
T17 1172-1178 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T18 1321-1327 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T19 1328-1334 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T20 1460-1466 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T21 1496-1521 Body_part denotes aortic smooth muscle cell http://purl.obolibrary.org/obo/CL_0002539

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-96 Sentence denotes Accumulation of glycosphingolipids in human atherosclerotic plaque and unaffected aorta tissues.
TextSentencer_T2 97-281 Sentence denotes We have measured the levels of glycosphingolipids and the activity of glycosphingolipid glycosyltransferases in human aortic intima and media from patients who died of atherosclerosis.
TextSentencer_T3 282-422 Sentence denotes The effects of lactosylceramide (LacCer) and glucosylceramide (GlcCer) from plaque intima on smooth muscle cell proliferation were assessed.
TextSentencer_T4 423-608 Sentence denotes When the GlcCer data was expressed as (micrograms GlcCer/mg cholesterol and/mg total phospholipid, a 28-fold and 7-fold increase in plaque intima compared to normal intima was observed.
TextSentencer_T5 609-716 Sentence denotes Similarly, the level of LacCer was elevated 5-fold and 4-fold, respectively, compared to unaffected intima.
TextSentencer_T6 717-855 Sentence denotes The activity of UDP-GlcCer: ceramide beta 1-->4 glucosyltransferase (GlcT-1) was similar in unaffected tissue, fatty streaks, and plaques.
TextSentencer_T7 856-895 Sentence denotes However, the activity of UDP-galactose:
TextSentencer_T8 896-1013 Sentence denotes GlcCer, beta 1-->4 galactosyltransferase (GalT-2) activity was moderately higher in plaque than in unaffected tissue.
TextSentencer_T9 1014-1355 Sentence denotes LacCer, but not GlcCer derived from plaque intima exerted a approximately 2.8-fold increase in the proliferation of human aortic smooth muscle cells grown in tissue culture compared to control presumably due to a marked increase in LacCer molecular species containing C16:0, C22:1, and C24:0 fatty acids in plaque intima compared to control.
TextSentencer_T10 1356-1536 Sentence denotes In sum, our findings provide an interesting and novel pathogenic mechanism of lactosylceramide mediated plaque formation via stimulation of aortic smooth muscle cell proliferation.
T1 0-96 Sentence denotes Accumulation of glycosphingolipids in human atherosclerotic plaque and unaffected aorta tissues.
T2 97-281 Sentence denotes We have measured the levels of glycosphingolipids and the activity of glycosphingolipid glycosyltransferases in human aortic intima and media from patients who died of atherosclerosis.
T3 282-422 Sentence denotes The effects of lactosylceramide (LacCer) and glucosylceramide (GlcCer) from plaque intima on smooth muscle cell proliferation were assessed.
T4 423-608 Sentence denotes When the GlcCer data was expressed as (micrograms GlcCer/mg cholesterol and/mg total phospholipid, a 28-fold and 7-fold increase in plaque intima compared to normal intima was observed.
T5 609-716 Sentence denotes Similarly, the level of LacCer was elevated 5-fold and 4-fold, respectively, compared to unaffected intima.
T6 717-855 Sentence denotes The activity of UDP-GlcCer: ceramide beta 1-->4 glucosyltransferase (GlcT-1) was similar in unaffected tissue, fatty streaks, and plaques.
T7 856-895 Sentence denotes However, the activity of UDP-galactose:
T8 896-1013 Sentence denotes GlcCer, beta 1-->4 galactosyltransferase (GalT-2) activity was moderately higher in plaque than in unaffected tissue.
T9 1014-1355 Sentence denotes LacCer, but not GlcCer derived from plaque intima exerted a approximately 2.8-fold increase in the proliferation of human aortic smooth muscle cells grown in tissue culture compared to control presumably due to a marked increase in LacCer molecular species containing C16:0, C22:1, and C24:0 fatty acids in plaque intima compared to control.
T10 1356-1536 Sentence denotes In sum, our findings provide an interesting and novel pathogenic mechanism of lactosylceramide mediated plaque formation via stimulation of aortic smooth muscle cell proliferation.
T1 0-96 Sentence denotes Accumulation of glycosphingolipids in human atherosclerotic plaque and unaffected aorta tissues.
T2 97-281 Sentence denotes We have measured the levels of glycosphingolipids and the activity of glycosphingolipid glycosyltransferases in human aortic intima and media from patients who died of atherosclerosis.
T3 282-422 Sentence denotes The effects of lactosylceramide (LacCer) and glucosylceramide (GlcCer) from plaque intima on smooth muscle cell proliferation were assessed.
T4 423-608 Sentence denotes When the GlcCer data was expressed as (micrograms GlcCer/mg cholesterol and/mg total phospholipid, a 28-fold and 7-fold increase in plaque intima compared to normal intima was observed.
T5 609-716 Sentence denotes Similarly, the level of LacCer was elevated 5-fold and 4-fold, respectively, compared to unaffected intima.
T6 717-855 Sentence denotes The activity of UDP-GlcCer: ceramide beta 1-->4 glucosyltransferase (GlcT-1) was similar in unaffected tissue, fatty streaks, and plaques.
T7 856-895 Sentence denotes However, the activity of UDP-galactose:
T8 896-1013 Sentence denotes GlcCer, beta 1-->4 galactosyltransferase (GalT-2) activity was moderately higher in plaque than in unaffected tissue.
T9 1014-1355 Sentence denotes LacCer, but not GlcCer derived from plaque intima exerted a approximately 2.8-fold increase in the proliferation of human aortic smooth muscle cells grown in tissue culture compared to control presumably due to a marked increase in LacCer molecular species containing C16:0, C22:1, and C24:0 fatty acids in plaque intima compared to control.
T10 1356-1536 Sentence denotes In sum, our findings provide an interesting and novel pathogenic mechanism of lactosylceramide mediated plaque formation via stimulation of aortic smooth muscle cell proliferation.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-96 Sentence denotes Accumulation of glycosphingolipids in human atherosclerotic plaque and unaffected aorta tissues.
T2 97-281 Sentence denotes We have measured the levels of glycosphingolipids and the activity of glycosphingolipid glycosyltransferases in human aortic intima and media from patients who died of atherosclerosis.
T3 282-422 Sentence denotes The effects of lactosylceramide (LacCer) and glucosylceramide (GlcCer) from plaque intima on smooth muscle cell proliferation were assessed.
T4 423-608 Sentence denotes When the GlcCer data was expressed as (micrograms GlcCer/mg cholesterol and/mg total phospholipid, a 28-fold and 7-fold increase in plaque intima compared to normal intima was observed.
T5 609-716 Sentence denotes Similarly, the level of LacCer was elevated 5-fold and 4-fold, respectively, compared to unaffected intima.
T6 717-855 Sentence denotes The activity of UDP-GlcCer: ceramide beta 1-->4 glucosyltransferase (GlcT-1) was similar in unaffected tissue, fatty streaks, and plaques.
T7 856-895 Sentence denotes However, the activity of UDP-galactose:
T8 896-1013 Sentence denotes GlcCer, beta 1-->4 galactosyltransferase (GalT-2) activity was moderately higher in plaque than in unaffected tissue.
T9 1014-1355 Sentence denotes LacCer, but not GlcCer derived from plaque intima exerted a approximately 2.8-fold increase in the proliferation of human aortic smooth muscle cells grown in tissue culture compared to control presumably due to a marked increase in LacCer molecular species containing C16:0, C22:1, and C24:0 fatty acids in plaque intima compared to control.
T10 1356-1536 Sentence denotes In sum, our findings provide an interesting and novel pathogenic mechanism of lactosylceramide mediated plaque formation via stimulation of aortic smooth muscle cell proliferation.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 297-313 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes lactosylceramide http://www.glycoepitope.jp/epitopes/EP0078
T2 315-321 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T3 633-639 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T4 1014-1020 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T5 1246-1252 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T6 1434-1450 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes lactosylceramide http://www.glycoepitope.jp/epitopes/EP0078

GlyCosmos15-Lectin-Jamboree

Id Subject Object Predicate Lexical cue glycosmos_id
T1 1282-1285 Lectin denotes C16 GL_005239

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 297-313 Glycan denotes lactosylceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T2 315-321 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T3 633-639 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T4 1014-1020 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T5 1246-1252 Glycan denotes LacCer https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW
T6 1434-1450 Glycan denotes lactosylceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G84224TW

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 38-43 OrganismTaxon denotes human 9606
T2 209-214 OrganismTaxon denotes human 9606
T3 1130-1135 OrganismTaxon denotes human 9606

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 82-87 Body_part denotes aorta FMA:3734
T2 88-95 Body_part denotes tissues FMA:9637
T3 375-393 Body_part denotes smooth muscle cell FMA:14072
T4 820-826 Body_part denotes tissue FMA:9637
T5 938-942 Body_part denotes GalT FMA:62820
T6 1006-1012 Body_part denotes tissue FMA:9637
T7 1143-1162 Body_part denotes smooth muscle cells FMA:14072
T8 1172-1178 Body_part denotes tissue FMA:9637
T9 1503-1521 Body_part denotes smooth muscle cell FMA:14072

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 82-87 Body_part denotes aorta http://purl.obolibrary.org/obo/MAT_0000035
T2 375-388 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303
T3 1143-1156 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303
T4 1503-1516 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 38-43 OrganismTaxon denotes human 9606
T2 209-214 OrganismTaxon denotes human 9606
T3 1130-1135 OrganismTaxon denotes human 9606

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 297-313 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes lactosylceramide http://www.glycoepitope.jp/epitopes/EP0078
T2 315-321 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T3 633-639 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T4 1014-1020 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T5 1246-1252 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes LacCer http://www.glycoepitope.jp/epitopes/EP0078
T6 1434-1450 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes lactosylceramide http://www.glycoepitope.jp/epitopes/EP0078

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 60-66 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T2 82-87 Body_part denotes aorta http://purl.obolibrary.org/obo/UBERON_0000947
T3 222-228 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T4 358-364 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T5 365-371 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T6 375-393 Body_part denotes smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192
T7 555-561 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T8 562-568 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T9 588-594 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T10 709-715 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T11 820-826 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T12 980-986 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T13 1006-1012 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T14 1050-1056 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T15 1057-1063 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T16 1136-1162 Body_part denotes aortic smooth muscle cells http://purl.obolibrary.org/obo/CL_0002539
T17 1172-1178 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T18 1321-1327 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T19 1328-1334 Body_part denotes intima http://purl.obolibrary.org/obo/UBERON_0002523
T20 1460-1466 Body_part denotes plaque http://purl.obolibrary.org/obo/UBERON_0016482
T21 1496-1521 Body_part denotes aortic smooth muscle cell http://purl.obolibrary.org/obo/CL_0002539

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 375-393 Cell denotes smooth muscle cell http://purl.obolibrary.org/obo/CL:0000192
T2 382-393 Cell denotes muscle cell http://purl.obolibrary.org/obo/CL:0000187
T3 1136-1162 Cell denotes aortic smooth muscle cells http://purl.obolibrary.org/obo/CL:0002539
T4 1143-1162 Cell denotes smooth muscle cells http://purl.obolibrary.org/obo/CL:0000192
T5 1496-1521 Cell denotes aortic smooth muscle cell http://purl.obolibrary.org/obo/CL:0002539
T6 1503-1521 Cell denotes smooth muscle cell http://purl.obolibrary.org/obo/CL:0000192
T7 1510-1521 Cell denotes muscle cell http://purl.obolibrary.org/obo/CL:0000187