PubMed:9001422
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-5 | protein | denotes | Elf-2 |
| T2 | 9-53 | protein | denotes | rhombotin-2 binding ets transcription factor |
| T3 | 104-115 | DNA | denotes | Rhombotin-2 |
| T4 | 117-123 | DNA | denotes | RBTN-2 |
| T5 | 130-144 | DNA | denotes | proto-oncogene |
| T6 | 168-181 | cell_type | denotes | T lymphocytes |
| T7 | 226-232 | protein | denotes | RBTN-2 |
| T8 | 266-281 | protein | denotes | binding protein |
| T9 | 340-352 | DNA | denotes | cDNA library |
| T10 | 370-400 | protein | denotes | novel ets transcription factor |
| T11 | 412-418 | protein | denotes | RBTN-2 |
| T12 | 443-448 | protein | denotes | elf-2 |
| T13 | 461-479 | protein | denotes | DNA-binding domain |
| T14 | 514-531 | protein | denotes | ets family member |
| T15 | 532-537 | protein | denotes | elf-1 |
| T16 | 586-603 | RNA | denotes | elf-2 transcripts |
| T17 | 654-664 | cell_type | denotes | Thymocytes |
| T18 | 715-732 | RNA | denotes | 3.5 kb transcript |
| T19 | 774-785 | DNA | denotes | cDNA clones |
| T20 | 859-872 | protein | denotes | amino termini |
| T21 | 943-949 | protein | denotes | elf-2a |
| T22 | 954-960 | protein | denotes | elf-2b |
| T23 | 980-1002 | protein | denotes | RBTN-2 binding regions |
| T24 | 1007-1026 | protein | denotes | DNA-binding domains |
| T25 | 1028-1034 | protein | denotes | Elf-2b |
| T26 | 1043-1074 | protein | denotes | putative transactivation domain |
| T27 | 1113-1119 | protein | denotes | RBTN-2 |
| T28 | 1152-1158 | protein | denotes | elf-2a |
| T29 | 1163-1169 | protein | denotes | elf-2b |
| T30 | 1189-1195 | protein | denotes | RBTN-2 |
| T31 | 1228-1235 | cell_type | denotes | T cells |
| T32 | 1237-1243 | protein | denotes | RBTN-2 |
| T33 | 1278-1284 | protein | denotes | elf-2b |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 9001422-0#0#5#gene1998 | 0-5 | gene1998 | denotes | Elf-2 |
| 9001422-0#9#20#gene4005 | 9-20 | gene4005 | denotes | rhombotin-2 |
| 9001422-0#87#102#diseaseC0023492 | 87-102 | diseaseC0023492 | denotes | T cell leukemia |
| 0#5#gene199887#102#diseaseC0023492 | 9001422-0#0#5#gene1998 | 9001422-0#87#102#diseaseC0023492 | associated_with | Elf-2,T cell leukemia |
| 9#20#gene400587#102#diseaseC0023492 | 9001422-0#9#20#gene4005 | 9001422-0#87#102#diseaseC0023492 | associated_with | rhombotin-2,T cell leukemia |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-103 | Sentence | denotes | Elf-2, a rhombotin-2 binding ets transcription factor: discovery and potential role in T cell leukemia. |
| S2 | 104-182 | Sentence | denotes | Rhombotin-2 (RBTN-2) is a proto-oncogene only in the context of T lymphocytes. |
| S3 | 183-317 | Sentence | denotes | We postulated that the oncogenic effect of RBTN-2 in T cells is likely mediated by binding protein(s) with T cell-specific expression. |
| S4 | 318-419 | Sentence | denotes | By screening a T cell cDNA library, we identified a novel ets transcription factor that binds RBTN-2. |
| S5 | 420-538 | Sentence | denotes | This protein was named elf-2 because its DNA-binding domain is virtually identical to that of ets family member elf-1. |
| S6 | 539-653 | Sentence | denotes | Northern analyses showed similar levels of two elf-2 transcripts (3.5 kb and 3.8 kb) in all tissues except thymus. |
| S7 | 654-752 | Sentence | denotes | Thymocytes expressed four- to 10-fold greater amounts of the 3.5 kb transcript than other tissues. |
| S8 | 753-926 | Sentence | denotes | Sequence analyses of cDNA clones indicated that these transcripts encode proteins differing only at their amino termini, and likely represent alternatively spliced isoforms. |
| S9 | 927-1027 | Sentence | denotes | These isoforms (elf-2a and elf-2b) contain identical RBTN-2 binding regions and DNA-binding domains. |
| S10 | 1028-1075 | Sentence | denotes | Elf-2b lacks a putative transactivation domain. |
| S11 | 1076-1170 | Sentence | denotes | The expression patterns suggest that RBTN-2 normally interacts equally with elf-2a and elf-2b. |
| S12 | 1171-1336 | Sentence | denotes | In contrast, when RBTN-2 is inappropriately expressed in T cells, RBTN-2 would interact predominantly with elf-2b; this interaction may lead to T cell proliferation. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-5 | NP | denotes | Elf-2 |
| C2 | 7-53 | NP | denotes | a rhombotin-2 binding ets transcription factor |
| C3 | 104-124 | NP | denotes | Rhombotin-2 (RBTN-2) |
| C4 | 226-232 | NP | denotes | RBTN-2 |
| C5 | 236-243 | NP | denotes | T cells |
| C7 | 368-400 | NP | denotes | a novel ets transcription factor |
| C8 | 401-405 | NP | denotes | that |
| C9 | 412-418 | NP | denotes | RBTN-2 |
| C6 | 368-418 | NP | denotes | a novel ets transcription factor that binds RBTN-2 |
| C10 | 420-432 | NP | denotes | This protein |
| C11 | 443-448 | NP | denotes | elf-2 |
| C13 | 457-460 | NP | denotes | its |
| C12 | 457-479 | NP | denotes | its DNA-binding domain |
| C14 | 506-510 | NP | denotes | that |
| C15 | 582-623 | NP | denotes | two elf-2 transcripts (3.5 kb and 3.8 kb) |
| C16 | 801-818 | NP | denotes | these transcripts |
| C17 | 826-834 | NP | denotes | proteins |
| C18 | 853-858 | NP | denotes | their |
| C19 | 895-925 | NP | denotes | alternatively spliced isoforms |
| C20 | 927-961 | NP | denotes | These isoforms (elf-2a and elf-2b) |
| C21 | 1028-1034 | NP | denotes | Elf-2b |
| C22 | 1113-1119 | NP | denotes | RBTN-2 |
| C23 | 1163-1169 | NP | denotes | elf-2b |
| C24 | 1189-1195 | NP | denotes | RBTN-2 |
| C25 | 1228-1235 | NP | denotes | T cells |
| C26 | 1237-1243 | NP | denotes | RBTN-2 |
| C27 | 1278-1284 | NP | denotes | elf-2b |
| R1 | C2 | C1 | coref-appos | a rhombotin-2 binding ets transcription factor,Elf-2 |
| R2 | C4 | C3 | coref-ident | RBTN-2,Rhombotin-2 (RBTN-2) |
| R3 | C8 | C7 | coref-relat | that,a novel ets transcription factor |
| R4 | C9 | C4 | coref-ident | RBTN-2,RBTN-2 |
| R5 | C6 | C1 | coref-ident | a novel ets transcription factor that binds RBTN-2,Elf-2 |
| R6 | C10 | C6 | coref-ident | This protein,a novel ets transcription factor that binds RBTN-2 |
| R7 | C11 | C10 | coref-ident | elf-2,This protein |
| R8 | C13 | C11 | coref-pron | its,elf-2 |
| R9 | C14 | C12 | coref-pron | that,its DNA-binding domain |
| R10 | C16 | C15 | coref-ident | these transcripts,two elf-2 transcripts (3.5 kb and 3.8 kb) |
| R11 | C18 | C17 | coref-pron | their,proteins |
| R12 | C20 | C19 | coref-ident | These isoforms (elf-2a and elf-2b),alternatively spliced isoforms |
| R13 | C22 | C9 | coref-ident | RBTN-2,RBTN-2 |
| R14 | C23 | C21 | coref-ident | elf-2b,Elf-2b |
| R15 | C24 | C22 | coref-ident | RBTN-2,RBTN-2 |
| R16 | C25 | C5 | coref-ident | T cells,T cells |
| R17 | C26 | C24 | coref-ident | RBTN-2,RBTN-2 |
| R18 | C27 | C23 | coref-ident | elf-2b,elf-2b |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-5 | protein_molecule | denotes | Elf-2 |
| T2 | 9-53 | protein_family_or_group | denotes | rhombotin-2 binding ets transcription factor |
| T3 | 87-102 | other_name | denotes | T cell leukemia |
| T4 | 104-115 | DNA_domain_or_region | denotes | Rhombotin-2 |
| T5 | 117-123 | DNA_domain_or_region | denotes | RBTN-2 |
| T6 | 130-144 | DNA_family_or_group | denotes | proto-oncogene |
| T7 | 168-181 | cell_type | denotes | T lymphocytes |
| T8 | 226-232 | protein_molecule | denotes | RBTN-2 |
| T9 | 266-281 | protein_family_or_group | denotes | binding protein |
| T10 | 290-316 | other_name | denotes | T cell-specific expression |
| T11 | 333-339 | other_name | denotes | T cell |
| T12 | 340-352 | DNA_family_or_group | denotes | cDNA library |
| T13 | 370-400 | protein_family_or_group | denotes | novel ets transcription factor |
| T14 | 412-418 | protein_molecule | denotes | RBTN-2 |
| T15 | 443-448 | protein_molecule | denotes | elf-2 |
| T16 | 461-479 | protein_domain_or_region | denotes | DNA-binding domain |
| T17 | 514-531 | protein_family_or_group | denotes | ets family member |
| T18 | 532-537 | protein_molecule | denotes | elf-1 |
| T19 | 539-556 | other_name | denotes | Northern analyses |
| T20 | 586-591 | protein_molecule | denotes | elf-2 |
| T21 | 654-664 | cell_type | denotes | Thymocytes |
| T22 | 715-732 | RNA_molecule | denotes | 3.5 kb transcript |
| T23 | 774-785 | DNA_family_or_group | denotes | cDNA clones |
| T24 | 859-872 | protein_domain_or_region | denotes | amino termini |
| T25 | 943-949 | protein_molecule | denotes | elf-2a |
| T26 | 954-960 | protein_molecule | denotes | elf-2b |
| T27 | 980-986 | protein_molecule | denotes | RBTN-2 |
| T28 | 1007-1026 | protein_domain_or_region | denotes | DNA-binding domains |
| T29 | 1028-1034 | protein_molecule | denotes | Elf-2b |
| T30 | 1043-1074 | protein_domain_or_region | denotes | putative transactivation domain |
| T31 | 1113-1119 | protein_molecule | denotes | RBTN-2 |
| T32 | 1152-1158 | protein_molecule | denotes | elf-2a |
| T33 | 1163-1169 | protein_molecule | denotes | elf-2b |
| T34 | 1189-1195 | protein_molecule | denotes | RBTN-2 |
| T35 | 1228-1235 | cell_type | denotes | T cells |
| T36 | 1237-1243 | protein_molecule | denotes | RBTN-2 |
| T37 | 1278-1284 | protein_molecule | denotes | elf-2b |
| T38 | 1315-1335 | other_name | denotes | T cell proliferation |