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PubMed:8991511 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 27-41 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T2 422-436 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T3 737-756 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T4 849-863 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T5 925-929 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T6 1066-1070 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T7 1161-1167 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T8 1214-1218 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T9 1363-1367 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T10 1512-1527 https://glytoucan.org/Structures/Glycans/G00058MO denotes polylactosamine
T11 1573-1577 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 27-41 Glycan_Motif denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T2 34-41 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T4 422-436 Glycan_Motif denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T5 429-436 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T7 737-756 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T8 849-863 Glycan_Motif denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T9 856-863 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T11 925-929 Glycan_Motif denotes sLex https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T12 1066-1070 Glycan_Motif denotes sLex https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T13 1161-1167 Glycan_Motif denotes fucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO
T14 1214-1218 Glycan_Motif denotes sLex https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T15 1363-1367 Glycan_Motif denotes sLex https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO
T16 1512-1527 Glycan_Motif denotes polylactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00058MO
T17 1573-1577 Glycan_Motif denotes sLex https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00054MO

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 27-41 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
T2 34-41 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
T3 422-436 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
T4 429-436 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
T5 849-863 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
T6 856-863 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 27-41 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T2 34-41 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T3 34-41 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T4 422-436 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T5 429-436 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T6 429-436 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T7 737-756 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T8 849-863 https://glytoucan.org/Structures/Glycans/G00054MO denotes sialyl Lewis x
T9 856-863 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T10 856-863 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T11 925-929 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T12 1066-1070 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T13 1161-1167 https://glytoucan.org/Structures/Glycans/G82576YO denotes fucose
T14 1214-1218 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T15 1363-1367 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex
T16 1512-1527 https://glytoucan.org/Structures/Glycans/G00058MO denotes polylactosamine
T17 1573-1577 https://glytoucan.org/Structures/Glycans/G00054MO denotes sLex

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 134-140 http://purl.obolibrary.org/obo/MAT_0000119 denotes Kidney
T2 1033-1039 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-133 Sentence denotes Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium.
T2 134-230 Sentence denotes Kidney transplant rejection is an inflammatory process characterized by lymphocyte infiltration.
T3 231-380 Sentence denotes Our earlier observations have shown that peritubular capillary endothelium (PTCE) is the site of lymphocyte entry into the rejecting renal allograft.
T4 381-515 Sentence denotes During rejection, PTCE begins to express sialyl Lewis x de novo, and binds lymphocytes by a mechanism largely dependent on L-selectin.
T5 516-691 Sentence denotes Hence, inhibiting the lymphocyte-endothelial interaction with oligosaccharide ligands of L-selectin offers an attractive possibility to prevent the inflammation and rejection.
T6 692-945 Sentence denotes Here, we report enzyme-assisted synthesis of N-acetyllactosamine-based tetra-, deca-, and docosameric saccharides carrying one, two or four distally located sialyl Lewis x groups [Neu-NAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc] (sLex), respectively.
T7 946-1197 Sentence denotes When tested for their ability to inhibit lymphocyte-endothelial interaction during rat kidney transplant rejection, all sLex-saccharides were inhibitors in the Stamper-Woodruff binding assays; the analogues lacking fucose showed no inhibitory potency.
T8 1198-1295 Sentence denotes The tetravalent sLex glycan proved to be a high-affinity adhesion inhibitor with an IC50 < 50 nM.
T9 1296-1434 Sentence denotes While less powerful than the tetravalent glycan, also the divalent sLex saccharide was a much better inhibitor than the monovalent glycan.
T10 1435-1639 Sentence denotes Hence, increasing multivalency and, possibly, increasing chain length of the polylactosamine backbone, enhances the inhibitory potency of sLex bearing glycans in the lymphocyte-endothelial adhesion assay.
T11 1640-1728 Sentence denotes This suggests that L-selectin behaves as a "functional oligomer" on lymphocyte surfaces.
T1 0-133 Sentence denotes Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium.
T2 134-230 Sentence denotes Kidney transplant rejection is an inflammatory process characterized by lymphocyte infiltration.
T3 231-380 Sentence denotes Our earlier observations have shown that peritubular capillary endothelium (PTCE) is the site of lymphocyte entry into the rejecting renal allograft.
T4 381-515 Sentence denotes During rejection, PTCE begins to express sialyl Lewis x de novo, and binds lymphocytes by a mechanism largely dependent on L-selectin.
T5 516-691 Sentence denotes Hence, inhibiting the lymphocyte-endothelial interaction with oligosaccharide ligands of L-selectin offers an attractive possibility to prevent the inflammation and rejection.
T6 692-945 Sentence denotes Here, we report enzyme-assisted synthesis of N-acetyllactosamine-based tetra-, deca-, and docosameric saccharides carrying one, two or four distally located sialyl Lewis x groups [Neu-NAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc] (sLex), respectively.
T7 946-1197 Sentence denotes When tested for their ability to inhibit lymphocyte-endothelial interaction during rat kidney transplant rejection, all sLex-saccharides were inhibitors in the Stamper-Woodruff binding assays; the analogues lacking fucose showed no inhibitory potency.
T8 1198-1295 Sentence denotes The tetravalent sLex glycan proved to be a high-affinity adhesion inhibitor with an IC50 < 50 nM.
T9 1296-1434 Sentence denotes While less powerful than the tetravalent glycan, also the divalent sLex saccharide was a much better inhibitor than the monovalent glycan.
T10 1435-1639 Sentence denotes Hence, increasing multivalency and, possibly, increasing chain length of the polylactosamine backbone, enhances the inhibitory potency of sLex bearing glycans in the lymphocyte-endothelial adhesion assay.
T11 1640-1728 Sentence denotes This suggests that L-selectin behaves as a "functional oligomer" on lymphocyte surfaces.

GlycoBiology-GDGDB

Id Subject Object Predicate Lexical cue
_T1 1292-1294 http://acgg.asia/db/diseases/gdgdb?con_ui=CON00386 denotes nM

ICD10

Id Subject Object Predicate Lexical cue
T1 134-161 http://purl.bioontology.org/ontology/ICD10/T86.1 denotes Kidney transplant rejection
T2 1033-1060 http://purl.bioontology.org/ontology/ICD10/T86.1 denotes kidney transplant rejection

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 79-89 FMAID:62933 denotes L-selectin
_T2 79-89 FMAID:62931 denotes L-selectin
_T3 79-89 FMAID:167265 denotes L-selectin
_T4 79-89 FMAID:167268 denotes L-selectin
_T5 79-89 FMAID:167267 denotes L-selectin
_T6 79-89 FMAID:62932 denotes L-selectin
_T7 81-89 FMAID:61795 denotes selectin
_T8 81-89 FMAID:165243 denotes selectin
_T9 99-109 FMAID:167174 denotes lymphocyte
_T10 99-109 FMAID:167163 denotes lymphocyte
_T11 99-109 FMAID:167176 denotes lymphocyte
_T12 99-109 FMAID:167173 denotes lymphocyte
_T13 99-109 FMAID:167171 denotes lymphocyte
_T14 99-109 FMAID:62869 denotes lymphocyte
_T15 99-109 FMAID:62863 denotes lymphocyte
_T16 99-109 FMAID:62870 denotes lymphocyte
_T17 121-132 FMAID:162384 denotes endothelium
_T18 121-132 FMAID:63916 denotes endothelium
_T19 134-140 FMAID:7203 denotes Kidney
_T20 134-140 FMAID:93681 denotes Kidney
_T21 203-216 FMAID:62869 denotes by lymphocyte
_T22 203-216 FMAID:167174 denotes by lymphocyte
_T23 203-216 FMAID:167171 denotes by lymphocyte
_T24 206-216 FMAID:167176 denotes lymphocyte
_T25 206-216 FMAID:167163 denotes lymphocyte
_T26 206-216 FMAID:167173 denotes lymphocyte
_T27 206-216 FMAID:62870 denotes lymphocyte
_T28 206-216 FMAID:62863 denotes lymphocyte
_T29 284-293 FMAID:63194 denotes capillary
_T30 284-293 FMAID:167591 denotes capillary
_T31 284-305 FMAID:67756 denotes capillary endothelium
_T32 284-305 FMAID:166383 denotes capillary endothelium
_T33 284-305 FMAID:166399 denotes capillary endothelium
_T34 294-305 FMAID:162384 denotes endothelium
_T35 294-305 FMAID:63916 denotes endothelium
_T36 320-338 FMAID:263010 denotes site of lymphocyte
_T37 320-338 FMAID:263009 denotes site of lymphocyte
_T38 328-338 FMAID:62870 denotes lymphocyte
_T39 328-338 FMAID:167163 denotes lymphocyte
_T40 328-338 FMAID:167171 denotes lymphocyte
_T41 328-338 FMAID:167174 denotes lymphocyte
_T42 328-338 FMAID:62863 denotes lymphocyte
_T43 328-338 FMAID:167176 denotes lymphocyte
_T44 328-338 FMAID:62869 denotes lymphocyte
_T45 328-338 FMAID:167173 denotes lymphocyte
_T46 450-467 FMAID:167174 denotes binds lymphocytes
_T47 450-467 FMAID:167171 denotes binds lymphocytes
_T48 450-467 FMAID:62869 denotes binds lymphocytes
_T49 456-467 FMAID:167176 denotes lymphocytes
_T50 456-467 FMAID:167163 denotes lymphocytes
_T51 456-467 FMAID:62870 denotes lymphocytes
_T52 456-467 FMAID:62863 denotes lymphocytes
_T53 456-467 FMAID:167173 denotes lymphocytes
_T54 504-514 FMAID:62932 denotes L-selectin
_T55 504-514 FMAID:167265 denotes L-selectin
_T56 504-514 FMAID:167268 denotes L-selectin
_T57 504-514 FMAID:62933 denotes L-selectin
_T58 504-514 FMAID:62931 denotes L-selectin
_T59 504-514 FMAID:167267 denotes L-selectin
_T60 506-514 FMAID:165243 denotes selectin
_T61 506-514 FMAID:61795 denotes selectin
_T62 538-548 FMAID:167176 denotes lymphocyte
_T63 538-548 FMAID:62869 denotes lymphocyte
_T64 538-548 FMAID:167174 denotes lymphocyte
_T65 538-548 FMAID:167171 denotes lymphocyte
_T66 538-548 FMAID:167173 denotes lymphocyte
_T67 538-548 FMAID:167163 denotes lymphocyte
_T68 538-548 FMAID:62870 denotes lymphocyte
_T69 538-548 FMAID:62863 denotes lymphocyte
_T70 549-560 FMAID:162384 denotes endothelial
_T71 549-560 FMAID:63916 denotes endothelial
_T72 578-593 FMAID:196731 denotes oligosaccharide
_T73 578-593 FMAID:82742 denotes oligosaccharide
_T74 605-615 FMAID:167268 denotes L-selectin
_T75 605-615 FMAID:62933 denotes L-selectin
_T76 605-615 FMAID:167265 denotes L-selectin
_T77 605-615 FMAID:167267 denotes L-selectin
_T78 605-615 FMAID:62932 denotes L-selectin
_T79 605-615 FMAID:62931 denotes L-selectin
_T80 607-615 FMAID:165243 denotes selectin
_T81 607-615 FMAID:61795 denotes selectin
_T82 737-756 FMAID:82786 denotes N-acetyllactosamine
_T83 737-756 FMAID:196780 denotes N-acetyllactosamine
_T84 794-805 FMAID:196733 denotes saccharides
_T85 794-805 FMAID:82744 denotes saccharides
_T86 832-840 FMAID:171166 denotes distally
_T87 832-840 FMAID:30327 denotes distally
_T88 951-957 FMAID:178661 denotes tested
_T89 987-997 FMAID:62870 denotes lymphocyte
_T90 987-997 FMAID:167174 denotes lymphocyte
_T91 987-997 FMAID:62869 denotes lymphocyte
_T92 987-997 FMAID:167176 denotes lymphocyte
_T93 987-997 FMAID:167171 denotes lymphocyte
_T94 987-997 FMAID:62863 denotes lymphocyte
_T95 987-997 FMAID:167173 denotes lymphocyte
_T96 987-997 FMAID:167163 denotes lymphocyte
_T97 998-1009 FMAID:63916 denotes endothelial
_T98 998-1009 FMAID:162384 denotes endothelial
_T99 1033-1039 FMAID:7203 denotes kidney
_T100 1033-1039 FMAID:93681 denotes kidney
_T101 1071-1082 FMAID:82744 denotes saccharides
_T102 1071-1082 FMAID:196733 denotes saccharides
_T103 1161-1167 FMAID:196784 denotes fucose
_T104 1161-1167 FMAID:82790 denotes fucose
_T105 1368-1378 FMAID:82744 denotes saccharide
_T106 1368-1378 FMAID:196733 denotes saccharide
_T107 1528-1536 FMAID:102867 denotes backbone
_T108 1601-1611 FMAID:167176 denotes lymphocyte
_T109 1601-1611 FMAID:62870 denotes lymphocyte
_T110 1601-1611 FMAID:167174 denotes lymphocyte
_T111 1601-1611 FMAID:62869 denotes lymphocyte
_T112 1601-1611 FMAID:167173 denotes lymphocyte
_T113 1601-1611 FMAID:167163 denotes lymphocyte
_T114 1601-1611 FMAID:62863 denotes lymphocyte
_T115 1601-1611 FMAID:167171 denotes lymphocyte
_T116 1612-1623 FMAID:162384 denotes endothelial
_T117 1612-1623 FMAID:63916 denotes endothelial
_T118 1659-1669 FMAID:62933 denotes L-selectin
_T119 1659-1669 FMAID:167265 denotes L-selectin
_T120 1659-1669 FMAID:62932 denotes L-selectin
_T121 1659-1669 FMAID:167268 denotes L-selectin
_T122 1659-1669 FMAID:62931 denotes L-selectin
_T123 1659-1669 FMAID:167267 denotes L-selectin
_T124 1661-1669 FMAID:165243 denotes selectin
_T125 1661-1669 FMAID:61795 denotes selectin
_T126 1708-1718 FMAID:62869 denotes lymphocyte
_T127 1708-1718 FMAID:62863 denotes lymphocyte
_T128 1708-1718 FMAID:167173 denotes lymphocyte
_T129 1708-1718 FMAID:167171 denotes lymphocyte
_T130 1708-1718 FMAID:167174 denotes lymphocyte
_T131 1708-1718 FMAID:167176 denotes lymphocyte
_T132 1708-1718 FMAID:62870 denotes lymphocyte
_T133 1708-1718 FMAID:167163 denotes lymphocyte
_T134 1719-1727 FMAID:50594 denotes surfaces
_T135 1719-1727 FMAID:146300 denotes surfaces

uniprot-human

Id Subject Object Predicate Lexical cue
T1 79-89 http://www.uniprot.org/uniprot/P14151 denotes L-selectin
T2 504-514 http://www.uniprot.org/uniprot/P14151 denotes L-selectin
T3 605-615 http://www.uniprot.org/uniprot/P14151 denotes L-selectin
T4 1659-1669 http://www.uniprot.org/uniprot/P14151 denotes L-selectin
T5 893-899 http://www.uniprot.org/uniprot/Q92988 denotes beta 1

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 79-89 http://www.uniprot.org/uniprot/P18337 denotes L-selectin
T2 504-514 http://www.uniprot.org/uniprot/P18337 denotes L-selectin
T3 605-615 http://www.uniprot.org/uniprot/P18337 denotes L-selectin
T4 1659-1669 http://www.uniprot.org/uniprot/P18337 denotes L-selectin

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 284-293 http://purl.bioontology.org/ontology/NCBITAXON/241203 denotes capillary
T2 284-293 http://purl.bioontology.org/ontology/NCBITAXON/119095 denotes capillary
T3 473-482 http://purl.bioontology.org/ontology/NCBITAXON/127244 denotes mechanism
T4 763-768 http://purl.bioontology.org/ontology/NCBITAXON/85284 denotes tetra
T5 763-768 http://purl.bioontology.org/ontology/NCBITAXON/1310384 denotes tetra
T6 864-870 http://purl.bioontology.org/ontology/STY/T096 denotes groups
T7 893-897 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T8 893-897 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T9 1354-1362 http://purl.bioontology.org/ontology/NCBITAXON/433098 denotes divalent

GO-BP

Id Subject Object Predicate Lexical cue
T1 0-9 http://purl.obolibrary.org/obo/GO_0009058 denotes Synthesis
T2 724-733 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T3 27-33 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T4 422-428 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T5 849-855 http://purl.obolibrary.org/obo/GO_0097503 denotes sialyl
T6 626-636 http://purl.obolibrary.org/obo/GO_0042056 denotes attractive
T7 664-676 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T8 724-756 http://purl.obolibrary.org/obo/GO_0030311 denotes synthesis of N-acetyllactosamine

GO-MF

Id Subject Object Predicate Lexical cue
T1 81-89 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T2 506-514 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T3 607-615 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T4 1661-1669 http://purl.obolibrary.org/obo/GO_0030246 denotes selectin
T5 110-117 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T6 450-455 http://purl.obolibrary.org/obo/GO_0070026 denotes binds
T7 110-117 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T8 450-455 http://purl.obolibrary.org/obo/GO_0003680 denotes binds
T9 110-117 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T10 450-455 http://purl.obolibrary.org/obo/GO_0017091 denotes binds
T11 110-117 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12 450-455 http://purl.obolibrary.org/obo/GO_0005488 denotes binds
T13 594-601 http://purl.obolibrary.org/obo/GO_0005488 denotes ligands

GO-CC

Id Subject Object Predicate Lexical cue
T1 876-879 http://purl.obolibrary.org/obo/GO_0005854 denotes NAc

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 121-132 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T2 294-305 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T3 272-293 http://purl.obolibrary.org/obo/UBERON_0005272 denotes peritubular capillary
T4 272-305 http://purl.obolibrary.org/obo/UBERON_0012441 denotes peritubular capillary endothelium
T5 284-293 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
T6 1033-1039 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 141-151 http://edamontology.org/topic_3421 denotes transplant
T2 561-572 http://edamontology.org/topic_0602 denotes interaction
T3 1010-1021 http://edamontology.org/topic_0602 denotes interaction
T4 1040-1050 http://edamontology.org/topic_3421 denotes transplant

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 181-188 http://edamontology.org/operation_0004 denotes process
T2 181-188 http://edamontology.org/operation_2409 denotes process
T3 701-707 http://edamontology.org/data_2048 denotes report
T4 1683-1694 http://edamontology.org/operation_0004 denotes "functional

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 916-922 chem:24139 denotes GlcNAc
T1 916-922 chem:24139 denotes GlcNAc

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 134-140 http://purl.obolibrary.org/obo/MAT_0000119 denotes Kidney
T2 1033-1039 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-133 Sentence denotes Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium.
TextSentencer_T2 134-230 Sentence denotes Kidney transplant rejection is an inflammatory process characterized by lymphocyte infiltration.
TextSentencer_T3 231-380 Sentence denotes Our earlier observations have shown that peritubular capillary endothelium (PTCE) is the site of lymphocyte entry into the rejecting renal allograft.
TextSentencer_T4 381-515 Sentence denotes During rejection, PTCE begins to express sialyl Lewis x de novo, and binds lymphocytes by a mechanism largely dependent on L-selectin.
TextSentencer_T5 516-691 Sentence denotes Hence, inhibiting the lymphocyte-endothelial interaction with oligosaccharide ligands of L-selectin offers an attractive possibility to prevent the inflammation and rejection.
TextSentencer_T6 692-945 Sentence denotes Here, we report enzyme-assisted synthesis of N-acetyllactosamine-based tetra-, deca-, and docosameric saccharides carrying one, two or four distally located sialyl Lewis x groups [Neu-NAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc] (sLex), respectively.
TextSentencer_T7 946-1197 Sentence denotes When tested for their ability to inhibit lymphocyte-endothelial interaction during rat kidney transplant rejection, all sLex-saccharides were inhibitors in the Stamper-Woodruff binding assays; the analogues lacking fucose showed no inhibitory potency.
TextSentencer_T8 1198-1295 Sentence denotes The tetravalent sLex glycan proved to be a high-affinity adhesion inhibitor with an IC50 < 50 nM.
TextSentencer_T9 1296-1434 Sentence denotes While less powerful than the tetravalent glycan, also the divalent sLex saccharide was a much better inhibitor than the monovalent glycan.
TextSentencer_T10 1435-1639 Sentence denotes Hence, increasing multivalency and, possibly, increasing chain length of the polylactosamine backbone, enhances the inhibitory potency of sLex bearing glycans in the lymphocyte-endothelial adhesion assay.
TextSentencer_T11 1640-1728 Sentence denotes This suggests that L-selectin behaves as a "functional oligomer" on lymphocyte surfaces.
T1 0-133 Sentence denotes Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium.
T2 134-230 Sentence denotes Kidney transplant rejection is an inflammatory process characterized by lymphocyte infiltration.
T3 231-380 Sentence denotes Our earlier observations have shown that peritubular capillary endothelium (PTCE) is the site of lymphocyte entry into the rejecting renal allograft.
T4 381-515 Sentence denotes During rejection, PTCE begins to express sialyl Lewis x de novo, and binds lymphocytes by a mechanism largely dependent on L-selectin.
T5 516-691 Sentence denotes Hence, inhibiting the lymphocyte-endothelial interaction with oligosaccharide ligands of L-selectin offers an attractive possibility to prevent the inflammation and rejection.
T6 692-945 Sentence denotes Here, we report enzyme-assisted synthesis of N-acetyllactosamine-based tetra-, deca-, and docosameric saccharides carrying one, two or four distally located sialyl Lewis x groups [Neu-NAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc] (sLex), respectively.
T7 946-1197 Sentence denotes When tested for their ability to inhibit lymphocyte-endothelial interaction during rat kidney transplant rejection, all sLex-saccharides were inhibitors in the Stamper-Woodruff binding assays; the analogues lacking fucose showed no inhibitory potency.
T8 1198-1295 Sentence denotes The tetravalent sLex glycan proved to be a high-affinity adhesion inhibitor with an IC50 < 50 nM.
T9 1296-1434 Sentence denotes While less powerful than the tetravalent glycan, also the divalent sLex saccharide was a much better inhibitor than the monovalent glycan.
T10 1435-1639 Sentence denotes Hence, increasing multivalency and, possibly, increasing chain length of the polylactosamine backbone, enhances the inhibitory potency of sLex bearing glycans in the lymphocyte-endothelial adhesion assay.
T11 1640-1728 Sentence denotes This suggests that L-selectin behaves as a "functional oligomer" on lymphocyte surfaces.
T1 0-133 Sentence denotes Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium.
T2 134-230 Sentence denotes Kidney transplant rejection is an inflammatory process characterized by lymphocyte infiltration.
T3 231-380 Sentence denotes Our earlier observations have shown that peritubular capillary endothelium (PTCE) is the site of lymphocyte entry into the rejecting renal allograft.
T4 381-515 Sentence denotes During rejection, PTCE begins to express sialyl Lewis x de novo, and binds lymphocytes by a mechanism largely dependent on L-selectin.
T5 516-691 Sentence denotes Hence, inhibiting the lymphocyte-endothelial interaction with oligosaccharide ligands of L-selectin offers an attractive possibility to prevent the inflammation and rejection.
T6 692-945 Sentence denotes Here, we report enzyme-assisted synthesis of N-acetyllactosamine-based tetra-, deca-, and docosameric saccharides carrying one, two or four distally located sialyl Lewis x groups [Neu-NAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc] (sLex), respectively.
T7 946-1197 Sentence denotes When tested for their ability to inhibit lymphocyte-endothelial interaction during rat kidney transplant rejection, all sLex-saccharides were inhibitors in the Stamper-Woodruff binding assays; the analogues lacking fucose showed no inhibitory potency.
T8 1198-1295 Sentence denotes The tetravalent sLex glycan proved to be a high-affinity adhesion inhibitor with an IC50 < 50 nM.
T9 1296-1434 Sentence denotes While less powerful than the tetravalent glycan, also the divalent sLex saccharide was a much better inhibitor than the monovalent glycan.
T10 1435-1639 Sentence denotes Hence, increasing multivalency and, possibly, increasing chain length of the polylactosamine backbone, enhances the inhibitory potency of sLex bearing glycans in the lymphocyte-endothelial adhesion assay.
T11 1640-1728 Sentence denotes This suggests that L-selectin behaves as a "functional oligomer" on lymphocyte surfaces.

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 27-39 http://rdf.glycoinfo.org/glycan/G00053MO denotes sialyl Lewis
T2 422-434 http://rdf.glycoinfo.org/glycan/G00053MO denotes sialyl Lewis
T3 849-861 http://rdf.glycoinfo.org/glycan/G00053MO denotes sialyl Lewis
T4 27-41 http://rdf.glycoinfo.org/glycan/G00054MO denotes sialyl Lewis x
T5 422-436 http://rdf.glycoinfo.org/glycan/G00054MO denotes sialyl Lewis x
T6 849-863 http://rdf.glycoinfo.org/glycan/G00054MO denotes sialyl Lewis x
T7 34-39 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T8 429-434 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T9 856-861 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T10 34-41 http://rdf.glycoinfo.org/glycan/G00051MO denotes Lewis x
T11 429-436 http://rdf.glycoinfo.org/glycan/G00051MO denotes Lewis x
T12 856-863 http://rdf.glycoinfo.org/glycan/G00051MO denotes Lewis x
T13 925-929 http://rdf.glycoinfo.org/glycan/G00054MO denotes sLex
T14 1066-1070 http://rdf.glycoinfo.org/glycan/G00054MO denotes sLex
T15 1214-1218 http://rdf.glycoinfo.org/glycan/G00054MO denotes sLex
T16 1363-1367 http://rdf.glycoinfo.org/glycan/G00054MO denotes sLex
T17 1573-1577 http://rdf.glycoinfo.org/glycan/G00054MO denotes sLex
T18 1512-1527 http://rdf.glycoinfo.org/glycan/G00058MO denotes polylactosamine

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 79-89 https://acgg.asia/db/lfdb/LfDB0142 denotes L-selectin
Lectin_T2 504-514 https://acgg.asia/db/lfdb/LfDB0142 denotes L-selectin
Lectin_T3 605-615 https://acgg.asia/db/lfdb/LfDB0142 denotes L-selectin
Lectin_T4 1659-1669 https://acgg.asia/db/lfdb/LfDB0142 denotes L-selectin
Lectin_T5 81-89 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T6 506-514 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T7 607-615 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T8 1661-1669 https://acgg.asia/db/lfdb/LfDB0013 denotes selectin
Lectin_T9 81-89 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T10 506-514 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T11 607-615 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin
Lectin_T12 1661-1669 https://acgg.asia/db/lfdb/LfDB0043 denotes selectin

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 27-39 http://www.glycoepitope.jp/epitopes/EP0008 denotes sialyl Lewis
PD-GlycoEpitope-B_T2 422-434 http://www.glycoepitope.jp/epitopes/EP0008 denotes sialyl Lewis
PD-GlycoEpitope-B_T3 849-861 http://www.glycoepitope.jp/epitopes/EP0008 denotes sialyl Lewis
PD-GlycoEpitope-B_T4 27-41 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
PD-GlycoEpitope-B_T5 422-436 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
PD-GlycoEpitope-B_T6 849-863 http://www.glycoepitope.jp/epitopes/EP0012 denotes sialyl Lewis x
PD-GlycoEpitope-B_T7 34-41 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
PD-GlycoEpitope-B_T8 429-436 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
PD-GlycoEpitope-B_T9 856-863 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 872-875 "http://rdf.glycoinfo.org/glycan/G16401VC" denotes Neu
GlycanIUPAC_T2 872-875 "http://rdf.glycoinfo.org/glycan/G84712AY" denotes Neu
GlycanIUPAC_T3 902-905 "http://rdf.glycoinfo.org/glycan/G49112ZN" denotes Fuc
GlycanIUPAC_T4 902-905 "http://rdf.glycoinfo.org/glycan/G50059AJ" denotes Fuc
GlycanIUPAC_T5 902-905 "http://rdf.glycoinfo.org/glycan/G76218YK" denotes Fuc
GlycanIUPAC_T6 902-905 "http://rdf.glycoinfo.org/glycan/G50102KR" denotes Fuc
GlycanIUPAC_T7 902-905 "http://rdf.glycoinfo.org/glycan/G10717VS" denotes Fuc
GlycanIUPAC_T8 902-905 "http://rdf.glycoinfo.org/glycan/G60524RK" denotes Fuc
GlycanIUPAC_T9 902-905 "http://rdf.glycoinfo.org/glycan/G84407TT" denotes Fuc
GlycanIUPAC_T10 902-905 "http://rdf.glycoinfo.org/glycan/G64717JT" denotes Fuc
GlycanIUPAC_T11 902-905 "http://rdf.glycoinfo.org/glycan/G45003TT" denotes Fuc
GlycanIUPAC_T12 902-905 "http://rdf.glycoinfo.org/glycan/G73923FP" denotes Fuc
GlycanIUPAC_T13 902-905 "http://rdf.glycoinfo.org/glycan/G78231MB" denotes Fuc
GlycanIUPAC_T14 902-905 "http://rdf.glycoinfo.org/glycan/G80487UG" denotes Fuc
GlycanIUPAC_T15 902-905 "http://rdf.glycoinfo.org/glycan/G29758MI" denotes Fuc
GlycanIUPAC_T16 902-905 "http://rdf.glycoinfo.org/glycan/G02671KD" denotes Fuc
GlycanIUPAC_T17 902-905 "http://rdf.glycoinfo.org/glycan/G57926TZ" denotes Fuc
GlycanIUPAC_T18 902-905 "http://rdf.glycoinfo.org/glycan/G41718FD" denotes Fuc
GlycanIUPAC_T19 902-905 "http://rdf.glycoinfo.org/glycan/G99840FL" denotes Fuc
GlycanIUPAC_T20 902-905 "http://rdf.glycoinfo.org/glycan/G64321UX" denotes Fuc
GlycanIUPAC_T21 902-905 "http://rdf.glycoinfo.org/glycan/G11231EG" denotes Fuc
GlycanIUPAC_T22 902-905 "http://rdf.glycoinfo.org/glycan/G62741TN" denotes Fuc
GlycanIUPAC_T23 902-905 "http://rdf.glycoinfo.org/glycan/G51576ZQ" denotes Fuc
GlycanIUPAC_T24 902-905 "http://rdf.glycoinfo.org/glycan/G66056LD" denotes Fuc
GlycanIUPAC_T25 902-905 "http://rdf.glycoinfo.org/glycan/G02768BF" denotes Fuc
GlycanIUPAC_T26 902-905 "http://rdf.glycoinfo.org/glycan/G26168RO" denotes Fuc
GlycanIUPAC_T27 902-905 "http://rdf.glycoinfo.org/glycan/G42890HL" denotes Fuc
GlycanIUPAC_T28 902-905 "http://rdf.glycoinfo.org/glycan/G17533VU" denotes Fuc
GlycanIUPAC_T29 902-905 "http://rdf.glycoinfo.org/glycan/G34306RG" denotes Fuc
GlycanIUPAC_T30 902-905 "http://rdf.glycoinfo.org/glycan/G88735KU" denotes Fuc
GlycanIUPAC_T31 902-905 "http://rdf.glycoinfo.org/glycan/G82605UA" denotes Fuc
GlycanIUPAC_T32 916-922 "http://rdf.glycoinfo.org/glycan/G26693XF" denotes GlcNAc
GlycanIUPAC_T33 916-922 "http://rdf.glycoinfo.org/glycan/G01864SU" denotes GlcNAc
GlycanIUPAC_T34 916-922 "http://rdf.glycoinfo.org/glycan/G17605FD" denotes GlcNAc
GlycanIUPAC_T35 916-922 "http://rdf.glycoinfo.org/glycan/G41950LU" denotes GlcNAc
GlycanIUPAC_T36 916-922 "http://rdf.glycoinfo.org/glycan/G57195RJ" denotes GlcNAc
GlycanIUPAC_T37 916-922 "http://rdf.glycoinfo.org/glycan/G85391SA" denotes GlcNAc
GlycanIUPAC_T38 916-922 "http://rdf.glycoinfo.org/glycan/G89565QL" denotes GlcNAc
GlycanIUPAC_T39 916-922 "http://rdf.glycoinfo.org/glycan/G80869MR" denotes GlcNAc
GlycanIUPAC_T40 916-922 "http://rdf.glycoinfo.org/glycan/G55978NL" denotes GlcNAc
GlycanIUPAC_T41 916-922 "http://rdf.glycoinfo.org/glycan/G54644LT" denotes GlcNAc
GlycanIUPAC_T42 916-922 "http://rdf.glycoinfo.org/glycan/G25694UG" denotes GlcNAc
GlycanIUPAC_T43 916-922 "http://rdf.glycoinfo.org/glycan/G25126RB" denotes GlcNAc
GlycanIUPAC_T44 916-922 "http://rdf.glycoinfo.org/glycan/G51848AD" denotes GlcNAc
GlycanIUPAC_T45 916-922 "http://rdf.glycoinfo.org/glycan/G94667GM" denotes GlcNAc
GlycanIUPAC_T46 916-922 "http://rdf.glycoinfo.org/glycan/G30124BO" denotes GlcNAc
GlycanIUPAC_T47 916-922 "http://rdf.glycoinfo.org/glycan/G82777EZ" denotes GlcNAc
GlycanIUPAC_T48 916-922 "http://rdf.glycoinfo.org/glycan/G10151YZ" denotes GlcNAc
GlycanIUPAC_T49 916-922 "http://rdf.glycoinfo.org/glycan/G17585ZM" denotes GlcNAc
GlycanIUPAC_T50 916-922 "http://rdf.glycoinfo.org/glycan/G04411CJ" denotes GlcNAc
GlycanIUPAC_T51 916-922 "http://rdf.glycoinfo.org/glycan/G38254HJ" denotes GlcNAc
GlycanIUPAC_T52 916-922 "http://rdf.glycoinfo.org/glycan/G75188FS" denotes GlcNAc
GlycanIUPAC_T53 916-922 "http://rdf.glycoinfo.org/glycan/G70374VG" denotes GlcNAc
GlycanIUPAC_T54 916-922 "http://rdf.glycoinfo.org/glycan/G45176LJ" denotes GlcNAc
GlycanIUPAC_T55 916-922 "http://rdf.glycoinfo.org/glycan/G30874VW" denotes GlcNAc
GlycanIUPAC_T56 916-922 "http://rdf.glycoinfo.org/glycan/G69333MI" denotes GlcNAc
GlycanIUPAC_T57 916-922 "http://rdf.glycoinfo.org/glycan/G10676XO" denotes GlcNAc
GlycanIUPAC_T58 916-922 "http://rdf.glycoinfo.org/glycan/G14843DJ" denotes GlcNAc
GlycanIUPAC_T59 916-922 "http://rdf.glycoinfo.org/glycan/G47546FR" denotes GlcNAc
GlycanIUPAC_T60 916-922 "http://rdf.glycoinfo.org/glycan/G73695ZM" denotes GlcNAc
GlycanIUPAC_T61 916-922 "http://rdf.glycoinfo.org/glycan/G31923TJ" denotes GlcNAc
GlycanIUPAC_T62 916-922 "http://rdf.glycoinfo.org/glycan/G60519EP" denotes GlcNAc
GlycanIUPAC_T63 916-922 "http://rdf.glycoinfo.org/glycan/G07933IA" denotes GlcNAc
GlycanIUPAC_T64 916-922 "http://rdf.glycoinfo.org/glycan/G40745NH" denotes GlcNAc
GlycanIUPAC_T65 916-922 "http://rdf.glycoinfo.org/glycan/G54496YV" denotes GlcNAc
GlycanIUPAC_T66 916-922 "http://rdf.glycoinfo.org/glycan/G62953SQ" denotes GlcNAc
GlycanIUPAC_T67 916-922 "http://rdf.glycoinfo.org/glycan/G70070AY" denotes GlcNAc
GlycanIUPAC_T68 916-922 "http://rdf.glycoinfo.org/glycan/G78792WC" denotes GlcNAc
GlycanIUPAC_T69 916-922 "http://rdf.glycoinfo.org/glycan/G25238AV" denotes GlcNAc
GlycanIUPAC_T70 916-922 "http://rdf.glycoinfo.org/glycan/G40510DP" denotes GlcNAc
GlycanIUPAC_T71 916-922 "http://rdf.glycoinfo.org/glycan/G61120TK" denotes GlcNAc
GlycanIUPAC_T72 916-922 "http://rdf.glycoinfo.org/glycan/G41342KV" denotes GlcNAc
GlycanIUPAC_T73 916-922 "http://rdf.glycoinfo.org/glycan/G90703NA" denotes GlcNAc
GlycanIUPAC_T74 916-922 "http://rdf.glycoinfo.org/glycan/G01591HR" denotes GlcNAc
GlycanIUPAC_T75 916-922 "http://rdf.glycoinfo.org/glycan/G56520XN" denotes GlcNAc
GlycanIUPAC_T76 916-922 "http://rdf.glycoinfo.org/glycan/G81830JX" denotes GlcNAc
GlycanIUPAC_T77 1062-1065 "http://rdf.glycoinfo.org/glycan/G41652MJ" denotes all
GlycanIUPAC_T78 1062-1065 "http://rdf.glycoinfo.org/glycan/G20761YC" denotes all
GlycanIUPAC_T79 1062-1065 "http://rdf.glycoinfo.org/glycan/G19807HM" denotes all
GlycanIUPAC_T80 1062-1065 "http://rdf.glycoinfo.org/glycan/G20351TE" denotes all
GlycanIUPAC_T81 1062-1065 "http://rdf.glycoinfo.org/glycan/G71957MR" denotes all
GlycanIUPAC_T82 1062-1065 "http://rdf.glycoinfo.org/glycan/G59040AE" denotes all
GlycanIUPAC_T83 1062-1065 "http://rdf.glycoinfo.org/glycan/G14987PW" denotes all
GlycanIUPAC_T84 1062-1065 "http://rdf.glycoinfo.org/glycan/G95064PC" denotes all
GlycanIUPAC_T85 1062-1065 "http://rdf.glycoinfo.org/glycan/G39143AQ" denotes all
GlycanIUPAC_T86 1062-1065 "http://rdf.glycoinfo.org/glycan/G65149OO" denotes all
GlycanIUPAC_T87 1062-1065 "http://rdf.glycoinfo.org/glycan/G02766SY" denotes all
GlycanIUPAC_T88 1062-1065 "http://rdf.glycoinfo.org/glycan/G26019KJ" denotes all
GlycanIUPAC_T89 1062-1065 "http://rdf.glycoinfo.org/glycan/G36429CZ" denotes all
GlycanIUPAC_T90 1062-1065 "http://rdf.glycoinfo.org/glycan/G89633TP" denotes all
GlycanIUPAC_T91 1062-1065 "http://rdf.glycoinfo.org/glycan/G28494FO" denotes all
GlycanIUPAC_T92 1062-1065 "http://rdf.glycoinfo.org/glycan/G06219CP" denotes all
GlycanIUPAC_T93 1062-1065 "http://rdf.glycoinfo.org/glycan/G44237SM" denotes all
GlycanIUPAC_T94 1062-1065 "http://rdf.glycoinfo.org/glycan/G57948RL" denotes all
GlycanIUPAC_T95 1062-1065 "http://rdf.glycoinfo.org/glycan/G64016DN" denotes all
GlycanIUPAC_T96 1062-1065 "http://rdf.glycoinfo.org/glycan/G14536PC" denotes all
GlycanIUPAC_T97 1062-1065 "http://rdf.glycoinfo.org/glycan/G14356FW" denotes all
GlycanIUPAC_T98 1062-1065 "http://rdf.glycoinfo.org/glycan/G34565UO" denotes all
GlycanIUPAC_T99 1062-1065 "http://rdf.glycoinfo.org/glycan/G67124MW" denotes all
GlycanIUPAC_T100 1062-1065 "http://rdf.glycoinfo.org/glycan/G71457ZU" denotes all
GlycanIUPAC_T101 1062-1065 "http://rdf.glycoinfo.org/glycan/G55228VZ" denotes all
GlycanIUPAC_T102 1062-1065 "http://rdf.glycoinfo.org/glycan/G31034MJ" denotes all
GlycanIUPAC_T103 1062-1065 "http://rdf.glycoinfo.org/glycan/G25776IP" denotes all
GlycanIUPAC_T104 1062-1065 "http://rdf.glycoinfo.org/glycan/G64442BV" denotes all
GlycanIUPAC_T105 1062-1065 "http://rdf.glycoinfo.org/glycan/G57018LE" denotes all
GlycanIUPAC_T106 1062-1065 "http://rdf.glycoinfo.org/glycan/G61761GX" denotes all
GlycanIUPAC_T107 1062-1065 "http://rdf.glycoinfo.org/glycan/G76318UX" denotes all
GlycanIUPAC_T108 1062-1065 "http://rdf.glycoinfo.org/glycan/G61906ER" denotes all
GlycanIUPAC_T109 1062-1065 "http://rdf.glycoinfo.org/glycan/G68723GR" denotes all
GlycanIUPAC_T110 1062-1065 "http://rdf.glycoinfo.org/glycan/G19540LE" denotes all
GlycanIUPAC_T111 1062-1065 "http://rdf.glycoinfo.org/glycan/G74944PO" denotes all
GlycanIUPAC_T112 1062-1065 "http://rdf.glycoinfo.org/glycan/G89489ZJ" denotes all
GlycanIUPAC_T113 1062-1065 "http://rdf.glycoinfo.org/glycan/G04434YU" denotes all
GlycanIUPAC_T114 1062-1065 "http://rdf.glycoinfo.org/glycan/G21450PB" denotes all
GlycanIUPAC_T115 1062-1065 "http://rdf.glycoinfo.org/glycan/G93629QY" denotes all
GlycanIUPAC_T116 1062-1065 "http://rdf.glycoinfo.org/glycan/G02603TR" denotes all
GlycanIUPAC_T117 1062-1065 "http://rdf.glycoinfo.org/glycan/G40280JP" denotes all
GlycanIUPAC_T118 1062-1065 "http://rdf.glycoinfo.org/glycan/G95259IC" denotes all
GlycanIUPAC_T119 1062-1065 "http://rdf.glycoinfo.org/glycan/G26900FE" denotes all
GlycanIUPAC_T120 1062-1065 "http://rdf.glycoinfo.org/glycan/G21346KK" denotes all
GlycanIUPAC_T121 1062-1065 "http://rdf.glycoinfo.org/glycan/G62509FF" denotes all
GlycanIUPAC_T122 1062-1065 "http://rdf.glycoinfo.org/glycan/G83932AK" denotes all
GlycanIUPAC_T123 1062-1065 "http://rdf.glycoinfo.org/glycan/G96978IB" denotes all
GlycanIUPAC_T124 1062-1065 "http://rdf.glycoinfo.org/glycan/G34275DN" denotes all
GlycanIUPAC_T125 1062-1065 "http://rdf.glycoinfo.org/glycan/G07071JF" denotes all
GlycanIUPAC_T126 1062-1065 "http://rdf.glycoinfo.org/glycan/G80639QD" denotes all
GlycanIUPAC_T127 1062-1065 "http://rdf.glycoinfo.org/glycan/G99460PJ" denotes all
GlycanIUPAC_T128 1062-1065 "http://rdf.glycoinfo.org/glycan/G22024BZ" denotes all
GlycanIUPAC_T129 1062-1065 "http://rdf.glycoinfo.org/glycan/G74097ZY" denotes all
GlycanIUPAC_T130 1062-1065 "http://rdf.glycoinfo.org/glycan/G84439YP" denotes all
GlycanIUPAC_T131 1062-1065 "http://rdf.glycoinfo.org/glycan/G52207WQ" denotes all
GlycanIUPAC_T132 1062-1065 "http://rdf.glycoinfo.org/glycan/G90695MS" denotes all
GlycanIUPAC_T133 1062-1065 "http://rdf.glycoinfo.org/glycan/G50398QX" denotes all
GlycanIUPAC_T134 1062-1065 "http://rdf.glycoinfo.org/glycan/G12166ZT" denotes all
GlycanIUPAC_T135 1062-1065 "http://rdf.glycoinfo.org/glycan/G48368BR" denotes all
GlycanIUPAC_T136 1062-1065 "http://rdf.glycoinfo.org/glycan/G57407RW" denotes all
GlycanIUPAC_T137 1062-1065 "http://rdf.glycoinfo.org/glycan/G00386TY" denotes all
GlycanIUPAC_T138 1062-1065 "http://rdf.glycoinfo.org/glycan/G18723JK" denotes all
GlycanIUPAC_T139 1062-1065 "http://rdf.glycoinfo.org/glycan/G93757OR" denotes all
GlycanIUPAC_T140 1062-1065 "http://rdf.glycoinfo.org/glycan/G29006SI" denotes all
GlycanIUPAC_T141 1062-1065 "http://rdf.glycoinfo.org/glycan/G03099OQ" denotes all
GlycanIUPAC_T142 1062-1065 "http://rdf.glycoinfo.org/glycan/G53739OW" denotes all
GlycanIUPAC_T143 1062-1065 "http://rdf.glycoinfo.org/glycan/G70440ZO" denotes all
GlycanIUPAC_T144 1062-1065 "http://rdf.glycoinfo.org/glycan/G29951RR" denotes all
GlycanIUPAC_T145 1062-1065 "http://rdf.glycoinfo.org/glycan/G58402TI" denotes all
GlycanIUPAC_T146 1062-1065 "http://rdf.glycoinfo.org/glycan/G39875TP" denotes all
GlycanIUPAC_T147 1062-1065 "http://rdf.glycoinfo.org/glycan/G83439QV" denotes all
GlycanIUPAC_T148 1062-1065 "http://rdf.glycoinfo.org/glycan/G41762RC" denotes all
GlycanIUPAC_T149 1062-1065 "http://rdf.glycoinfo.org/glycan/G91604UI" denotes all
GlycanIUPAC_T150 1062-1065 "http://rdf.glycoinfo.org/glycan/G88447WE" denotes all
GlycanIUPAC_T151 1062-1065 "http://rdf.glycoinfo.org/glycan/G93634BS" denotes all
GlycanIUPAC_T152 1062-1065 "http://rdf.glycoinfo.org/glycan/G02587BH" denotes all
GlycanIUPAC_T153 1062-1065 "http://rdf.glycoinfo.org/glycan/G43511MX" denotes all
GlycanIUPAC_T154 1062-1065 "http://rdf.glycoinfo.org/glycan/G64958DH" denotes all
GlycanIUPAC_T155 1062-1065 "http://rdf.glycoinfo.org/glycan/G30384TR" denotes all
GlycanIUPAC_T156 1062-1065 "http://rdf.glycoinfo.org/glycan/G15624EX" denotes all
GlycanIUPAC_T157 1062-1065 "http://rdf.glycoinfo.org/glycan/G22706ST" denotes all
GlycanIUPAC_T158 1062-1065 "http://rdf.glycoinfo.org/glycan/G57408PI" denotes all
GlycanIUPAC_T159 1062-1065 "http://rdf.glycoinfo.org/glycan/G86403XX" denotes all
GlycanIUPAC_T160 1062-1065 "http://rdf.glycoinfo.org/glycan/G78043YB" denotes all
GlycanIUPAC_T161 1062-1065 "http://rdf.glycoinfo.org/glycan/G18952JK" denotes all
GlycanIUPAC_T162 1062-1065 "http://rdf.glycoinfo.org/glycan/G49020ND" denotes all
GlycanIUPAC_T163 1062-1065 "http://rdf.glycoinfo.org/glycan/G63590YW" denotes all
GlycanIUPAC_T164 1062-1065 "http://rdf.glycoinfo.org/glycan/G22793KS" denotes all
GlycanIUPAC_T165 1062-1065 "http://rdf.glycoinfo.org/glycan/G64134SS" denotes all
GlycanIUPAC_T166 1062-1065 "http://rdf.glycoinfo.org/glycan/G17338HY" denotes all
GlycanIUPAC_T167 1062-1065 "http://rdf.glycoinfo.org/glycan/G99745XF" denotes all
GlycanIUPAC_T168 1062-1065 "http://rdf.glycoinfo.org/glycan/G27782HN" denotes all
GlycanIUPAC_T169 1062-1065 "http://rdf.glycoinfo.org/glycan/G57496DC" denotes all
GlycanIUPAC_T170 1062-1065 "http://rdf.glycoinfo.org/glycan/G93169WB" denotes all
GlycanIUPAC_T171 1062-1065 "http://rdf.glycoinfo.org/glycan/G05518TD" denotes all
GlycanIUPAC_T172 1062-1065 "http://rdf.glycoinfo.org/glycan/G62603DN" denotes all
GlycanIUPAC_T173 1062-1065 "http://rdf.glycoinfo.org/glycan/G59574FS" denotes all
GlycanIUPAC_T174 1062-1065 "http://rdf.glycoinfo.org/glycan/G47567WC" denotes all

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 121-132 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
PD-UBERON-AE-B_T2 294-305 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
PD-UBERON-AE-B_T3 134-140 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
PD-UBERON-AE-B_T4 1033-1039 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
PD-UBERON-AE-B_T5 272-293 http://purl.obolibrary.org/obo/UBERON_0005272 denotes peritubular capillary
PD-UBERON-AE-B_T6 272-305 http://purl.obolibrary.org/obo/UBERON_0012441 denotes peritubular capillary endothelium
PD-UBERON-AE-B_T7 284-293 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T8 284-305 http://purl.obolibrary.org/obo/UBERON_0001915 denotes capillary endothelium

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 664-676 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 27-41 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T2 422-436 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T3 849-863 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T4 872-879 Glycan denotes Neu-NAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 27-41 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T2 422-436 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T3 849-863 Glycan denotes sialyl Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00054MO
T4 872-879 Glycan denotes Neu-NAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 27-41 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012
T2 422-436 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012
T3 849-863 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 1029-1032 Organism denotes rat 10114|10116

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 99-109 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T2 206-216 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T3 328-338 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T4 456-467 Cell denotes lymphocytes http://purl.obolibrary.org/obo/CL:0000542
T5 538-548 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T6 987-997 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T7 1601-1611 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T8 1708-1718 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 99-109 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T2 121-132 Body_part denotes endothelium http://purl.obolibrary.org/obo/UBERON_0001986
T3 134-140 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T4 206-216 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T5 272-305 Body_part denotes peritubular capillary endothelium http://purl.obolibrary.org/obo/UBERON_0012441
T6 307-311 Body_part denotes PTCE http://purl.obolibrary.org/obo/UBERON_0012441
T7 328-338 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T8 399-403 Body_part denotes PTCE http://purl.obolibrary.org/obo/UBERON_0012441
T9 456-467 Body_part denotes lymphocytes http://purl.obolibrary.org/obo/CL_0000542
T10 538-548 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T11 987-997 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T12 1033-1039 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T13 1528-1536 Body_part denotes backbone http://purl.obolibrary.org/obo/UBERON_0001130
T14 1601-1611 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T15 1708-1718 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-133 Sentence denotes Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium.
T2 134-230 Sentence denotes Kidney transplant rejection is an inflammatory process characterized by lymphocyte infiltration.
T3 231-380 Sentence denotes Our earlier observations have shown that peritubular capillary endothelium (PTCE) is the site of lymphocyte entry into the rejecting renal allograft.
T4 381-515 Sentence denotes During rejection, PTCE begins to express sialyl Lewis x de novo, and binds lymphocytes by a mechanism largely dependent on L-selectin.
T5 516-691 Sentence denotes Hence, inhibiting the lymphocyte-endothelial interaction with oligosaccharide ligands of L-selectin offers an attractive possibility to prevent the inflammation and rejection.
T6 692-945 Sentence denotes Here, we report enzyme-assisted synthesis of N-acetyllactosamine-based tetra-, deca-, and docosameric saccharides carrying one, two or four distally located sialyl Lewis x groups [Neu-NAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc] (sLex), respectively.
T7 946-1197 Sentence denotes When tested for their ability to inhibit lymphocyte-endothelial interaction during rat kidney transplant rejection, all sLex-saccharides were inhibitors in the Stamper-Woodruff binding assays; the analogues lacking fucose showed no inhibitory potency.
T8 1198-1295 Sentence denotes The tetravalent sLex glycan proved to be a high-affinity adhesion inhibitor with an IC50 < 50 nM.
T9 1296-1434 Sentence denotes While less powerful than the tetravalent glycan, also the divalent sLex saccharide was a much better inhibitor than the monovalent glycan.
T10 1435-1639 Sentence denotes Hence, increasing multivalency and, possibly, increasing chain length of the polylactosamine backbone, enhances the inhibitory potency of sLex bearing glycans in the lymphocyte-endothelial adhesion assay.
T11 1640-1728 Sentence denotes This suggests that L-selectin behaves as a "functional oligomer" on lymphocyte surfaces.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 27-41 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012
T2 422-436 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012
T3 849-863 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes sialyl Lewis x http://www.glycoepitope.jp/epitopes/EP0012

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 99-109 Body_part denotes lymphocyte FMA:62863
T2 121-132 Body_part denotes endothelium FMA:63916
T3 134-140 Body_part denotes Kidney FMA:7203
T4 206-216 Body_part denotes lymphocyte FMA:62863
T5 284-305 Body_part denotes capillary endothelium FMA:62114
T6 328-338 Body_part denotes lymphocyte FMA:62863
T7 456-467 Body_part denotes lymphocytes FMA:62863
T8 538-548 Body_part denotes lymphocyte FMA:62863
T9 987-997 Body_part denotes lymphocyte FMA:62863
T10 1033-1039 Body_part denotes kidney FMA:7203
T11 1528-1536 Body_part denotes backbone FMA:13478
T12 1601-1611 Body_part denotes lymphocyte FMA:62863
T13 1708-1718 Body_part denotes lymphocyte FMA:62863

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 134-140 Body_part denotes Kidney http://purl.obolibrary.org/obo/MAT_0000119
T2 1033-1039 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 1029-1032 OrganismTaxon denotes rat 10114|10116

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 99-109 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T2 121-132 Body_part denotes endothelium http://purl.obolibrary.org/obo/UBERON_0001986
T3 134-140 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T4 206-216 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T5 272-305 Body_part denotes peritubular capillary endothelium http://purl.obolibrary.org/obo/UBERON_0012441
T6 328-338 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T7 456-467 Body_part denotes lymphocytes http://purl.obolibrary.org/obo/CL_0000542
T8 538-548 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T9 987-997 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T10 1033-1039 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T11 1528-1536 Body_part denotes backbone http://purl.obolibrary.org/obo/UBERON_0001130
T12 1601-1611 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542
T13 1708-1718 Body_part denotes lymphocyte http://purl.obolibrary.org/obo/CL_0000542

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 134-140 Body_part denotes Kidney http://purl.obolibrary.org/obo/MAT_0000119
T2 1033-1039 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 99-109 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T2 206-216 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T3 328-338 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T4 456-467 Cell denotes lymphocytes http://purl.obolibrary.org/obo/CL:0000542
T5 538-548 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T6 987-997 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T7 1601-1611 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T8 1708-1718 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542