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Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 352-357 http://purl.obolibrary.org/obo/MAT_0000239 denotes stems

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-113 Sentence denotes Glycosylation of native MHC class Ia molecules is required for recognition by allogeneic cytotoxic T lymphocytes.
TextSentencer_T2 114-286 Sentence denotes The question whether or not target cell N-linked carbohydrate participates in cytotoxic T lymphocyte (CTL) mediated cytolysis has been in contention for well over a decade.
TextSentencer_T3 287-443 Sentence denotes Much of the evidence supporting a role for N-linked carbohydrate stems from the treatment of target cells with the glycosylation inhibitor tunicamycin (TM).
TextSentencer_T4 444-653 Sentence denotes In this report, we show that treatment of targets with TM, but not other inhibitors of complex carbohydrate formation (swainsonine, 1-deoxynojirimycin, and 1-deoxymannojirimycin), abrogates the lytic response.
TextSentencer_T5 654-834 Sentence denotes We conclude that N-linked complex carbohydrates are not absolutely required for the maturation or function of any target cell glycoconjugate directly involved in the lytic process.
TextSentencer_T6 835-974 Sentence denotes However, we show that TM treatment of target cells leads to the loss of an MHC class Ia epitope known to be required for T cell triggering.
TextSentencer_T7 975-1112 Sentence denotes Further, we show that only target cells expressing class Ia molecules with functional glycosylation sequons are subject to the TM effect.
TextSentencer_T8 1113-1307 Sentence denotes From these results we conclude that while N-linked glycosylation of native MHC class Ia molecules is required for antigen presentation, the exact structural motif of the glycan is not important.
T1 0-113 Sentence denotes Glycosylation of native MHC class Ia molecules is required for recognition by allogeneic cytotoxic T lymphocytes.
T2 114-286 Sentence denotes The question whether or not target cell N-linked carbohydrate participates in cytotoxic T lymphocyte (CTL) mediated cytolysis has been in contention for well over a decade.
T3 287-443 Sentence denotes Much of the evidence supporting a role for N-linked carbohydrate stems from the treatment of target cells with the glycosylation inhibitor tunicamycin (TM).
T4 444-653 Sentence denotes In this report, we show that treatment of targets with TM, but not other inhibitors of complex carbohydrate formation (swainsonine, 1-deoxynojirimycin, and 1-deoxymannojirimycin), abrogates the lytic response.
T5 654-834 Sentence denotes We conclude that N-linked complex carbohydrates are not absolutely required for the maturation or function of any target cell glycoconjugate directly involved in the lytic process.
T6 835-974 Sentence denotes However, we show that TM treatment of target cells leads to the loss of an MHC class Ia epitope known to be required for T cell triggering.
T7 975-1112 Sentence denotes Further, we show that only target cells expressing class Ia molecules with functional glycosylation sequons are subject to the TM effect.
T8 1113-1307 Sentence denotes From these results we conclude that while N-linked glycosylation of native MHC class Ia molecules is required for antigen presentation, the exact structural motif of the glycan is not important.
T1 0-113 Sentence denotes Glycosylation of native MHC class Ia molecules is required for recognition by allogeneic cytotoxic T lymphocytes.
T2 114-286 Sentence denotes The question whether or not target cell N-linked carbohydrate participates in cytotoxic T lymphocyte (CTL) mediated cytolysis has been in contention for well over a decade.
T3 287-443 Sentence denotes Much of the evidence supporting a role for N-linked carbohydrate stems from the treatment of target cells with the glycosylation inhibitor tunicamycin (TM).
T4 444-653 Sentence denotes In this report, we show that treatment of targets with TM, but not other inhibitors of complex carbohydrate formation (swainsonine, 1-deoxynojirimycin, and 1-deoxymannojirimycin), abrogates the lytic response.
T5 654-834 Sentence denotes We conclude that N-linked complex carbohydrates are not absolutely required for the maturation or function of any target cell glycoconjugate directly involved in the lytic process.
T6 835-974 Sentence denotes However, we show that TM treatment of target cells leads to the loss of an MHC class Ia epitope known to be required for T cell triggering.
T7 975-1112 Sentence denotes Further, we show that only target cells expressing class Ia molecules with functional glycosylation sequons are subject to the TM effect.
T8 1113-1307 Sentence denotes From these results we conclude that while N-linked glycosylation of native MHC class Ia molecules is required for antigen presentation, the exact structural motif of the glycan is not important.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 24-27 FMAID:198016 denotes MHC
_T2 89-112 FMAID:197291 denotes cytotoxic T lymphocytes
_T3 89-112 FMAID:197892 denotes cytotoxic T lymphocytes
_T4 99-112 FMAID:62869 denotes T lymphocytes
_T5 99-112 FMAID:167174 denotes T lymphocytes
_T6 99-112 FMAID:167171 denotes T lymphocytes
_T7 99-112 FMAID:62870 denotes T lymphocytes
_T8 99-112 FMAID:167176 denotes T lymphocytes
_T9 99-112 FMAID:167173 denotes T lymphocytes
_T10 101-112 FMAID:167163 denotes lymphocytes
_T11 101-112 FMAID:62863 denotes lymphocytes
_T12 163-175 FMAID:197276 denotes carbohydrate
_T13 163-175 FMAID:82737 denotes carbohydrate
_T14 192-214 FMAID:197291 denotes cytotoxic T lymphocyte
_T15 192-214 FMAID:197892 denotes cytotoxic T lymphocyte
_T16 202-214 FMAID:167171 denotes T lymphocyte
_T17 202-214 FMAID:62869 denotes T lymphocyte
_T18 202-214 FMAID:167176 denotes T lymphocyte
_T19 202-214 FMAID:62870 denotes T lymphocyte
_T20 202-214 FMAID:167174 denotes T lymphocyte
_T21 202-214 FMAID:167173 denotes T lymphocyte
_T22 204-214 FMAID:62863 denotes lymphocyte
_T23 204-214 FMAID:167163 denotes lymphocyte
_T24 339-351 FMAID:82737 denotes carbohydrate
_T25 339-351 FMAID:197276 denotes carbohydrate
_T26 387-392 FMAID:169002 denotes cells
_T27 387-392 FMAID:68646 denotes cells
_T28 539-551 FMAID:197276 denotes carbohydrate
_T29 539-551 FMAID:82737 denotes carbohydrate
_T30 688-701 FMAID:197276 denotes carbohydrates
_T31 688-701 FMAID:82737 denotes carbohydrates
_T32 780-794 FMAID:196776 denotes glycoconjugate
_T33 780-794 FMAID:82782 denotes glycoconjugate
_T34 880-885 FMAID:169002 denotes cells
_T35 880-885 FMAID:68646 denotes cells
_T36 910-913 FMAID:198016 denotes MHC
_T37 1009-1014 FMAID:68646 denotes cells
_T38 1009-1014 FMAID:169002 denotes cells
_T39 1188-1191 FMAID:198016 denotes MHC
_T40 1227-1247 FMAID:273572 denotes antigen presentation
_T41 1227-1247 FMAID:273565 denotes antigen presentation
_T42 1227-1247 FMAID:273564 denotes antigen presentation

uniprot-human

Id Subject Object Predicate Lexical cue
T1 439-441 http://www.uniprot.org/uniprot/P07204 denotes TM
T2 499-501 http://www.uniprot.org/uniprot/P07204 denotes TM
T3 857-859 http://www.uniprot.org/uniprot/P07204 denotes TM
T4 1102-1104 http://www.uniprot.org/uniprot/P07204 denotes TM
T5 439-441 http://www.uniprot.org/uniprot/Q14264 denotes TM
T6 499-501 http://www.uniprot.org/uniprot/Q14264 denotes TM
T7 857-859 http://www.uniprot.org/uniprot/Q14264 denotes TM
T8 1102-1104 http://www.uniprot.org/uniprot/Q14264 denotes TM
T9 439-441 http://www.uniprot.org/uniprot/P60507 denotes TM
T10 499-501 http://www.uniprot.org/uniprot/P60507 denotes TM
T11 857-859 http://www.uniprot.org/uniprot/P60507 denotes TM
T12 1102-1104 http://www.uniprot.org/uniprot/P60507 denotes TM
T13 439-441 http://www.uniprot.org/uniprot/P60608 denotes TM
T14 499-501 http://www.uniprot.org/uniprot/P60608 denotes TM
T15 857-859 http://www.uniprot.org/uniprot/P60608 denotes TM
T16 1102-1104 http://www.uniprot.org/uniprot/P60608 denotes TM
T17 439-441 http://www.uniprot.org/uniprot/P60508 denotes TM
T18 499-501 http://www.uniprot.org/uniprot/P60508 denotes TM
T19 857-859 http://www.uniprot.org/uniprot/P60508 denotes TM
T20 1102-1104 http://www.uniprot.org/uniprot/P60508 denotes TM
T21 439-441 http://www.uniprot.org/uniprot/Q902F9 denotes TM
T22 499-501 http://www.uniprot.org/uniprot/Q902F9 denotes TM
T23 857-859 http://www.uniprot.org/uniprot/Q902F9 denotes TM
T24 1102-1104 http://www.uniprot.org/uniprot/Q902F9 denotes TM
T25 439-441 http://www.uniprot.org/uniprot/Q9NX77 denotes TM
T26 499-501 http://www.uniprot.org/uniprot/Q9NX77 denotes TM
T27 857-859 http://www.uniprot.org/uniprot/Q9NX77 denotes TM
T28 1102-1104 http://www.uniprot.org/uniprot/Q9NX77 denotes TM
T29 439-441 http://www.uniprot.org/uniprot/O42043 denotes TM
T30 499-501 http://www.uniprot.org/uniprot/O42043 denotes TM
T31 857-859 http://www.uniprot.org/uniprot/O42043 denotes TM
T32 1102-1104 http://www.uniprot.org/uniprot/O42043 denotes TM
T33 439-441 http://www.uniprot.org/uniprot/O71037 denotes TM
T34 499-501 http://www.uniprot.org/uniprot/O71037 denotes TM
T35 857-859 http://www.uniprot.org/uniprot/O71037 denotes TM
T36 1102-1104 http://www.uniprot.org/uniprot/O71037 denotes TM
T37 439-441 http://www.uniprot.org/uniprot/P61565 denotes TM
T38 499-501 http://www.uniprot.org/uniprot/P61565 denotes TM
T39 857-859 http://www.uniprot.org/uniprot/P61565 denotes TM
T40 1102-1104 http://www.uniprot.org/uniprot/P61565 denotes TM
T41 439-441 http://www.uniprot.org/uniprot/P61566 denotes TM
T42 499-501 http://www.uniprot.org/uniprot/P61566 denotes TM
T43 857-859 http://www.uniprot.org/uniprot/P61566 denotes TM
T44 1102-1104 http://www.uniprot.org/uniprot/P61566 denotes TM
T45 439-441 http://www.uniprot.org/uniprot/P61570 denotes TM
T46 499-501 http://www.uniprot.org/uniprot/P61570 denotes TM
T47 857-859 http://www.uniprot.org/uniprot/P61570 denotes TM
T48 1102-1104 http://www.uniprot.org/uniprot/P61570 denotes TM
T49 439-441 http://www.uniprot.org/uniprot/Q69384 denotes TM
T50 499-501 http://www.uniprot.org/uniprot/Q69384 denotes TM
T51 857-859 http://www.uniprot.org/uniprot/Q69384 denotes TM
T52 1102-1104 http://www.uniprot.org/uniprot/Q69384 denotes TM
T53 439-441 http://www.uniprot.org/uniprot/P61567 denotes TM
T54 499-501 http://www.uniprot.org/uniprot/P61567 denotes TM
T55 857-859 http://www.uniprot.org/uniprot/P61567 denotes TM
T56 1102-1104 http://www.uniprot.org/uniprot/P61567 denotes TM
T57 439-441 http://www.uniprot.org/uniprot/Q902F8 denotes TM
T58 499-501 http://www.uniprot.org/uniprot/Q902F8 denotes TM
T59 857-859 http://www.uniprot.org/uniprot/Q902F8 denotes TM
T60 1102-1104 http://www.uniprot.org/uniprot/Q902F8 denotes TM
T61 439-441 http://www.uniprot.org/uniprot/Q9UKH3 denotes TM
T62 499-501 http://www.uniprot.org/uniprot/Q9UKH3 denotes TM
T63 857-859 http://www.uniprot.org/uniprot/Q9UKH3 denotes TM
T64 1102-1104 http://www.uniprot.org/uniprot/Q9UKH3 denotes TM
T65 439-441 http://www.uniprot.org/uniprot/P60509 denotes TM
T66 499-501 http://www.uniprot.org/uniprot/P60509 denotes TM
T67 857-859 http://www.uniprot.org/uniprot/P60509 denotes TM
T68 1102-1104 http://www.uniprot.org/uniprot/P60509 denotes TM
T69 439-441 http://www.uniprot.org/uniprot/P61550 denotes TM
T70 499-501 http://www.uniprot.org/uniprot/P61550 denotes TM
T71 857-859 http://www.uniprot.org/uniprot/P61550 denotes TM
T72 1102-1104 http://www.uniprot.org/uniprot/P61550 denotes TM
T73 439-441 http://www.uniprot.org/uniprot/Q9UQF0 denotes TM
T74 499-501 http://www.uniprot.org/uniprot/Q9UQF0 denotes TM
T75 857-859 http://www.uniprot.org/uniprot/Q9UQF0 denotes TM
T76 1102-1104 http://www.uniprot.org/uniprot/Q9UQF0 denotes TM
T77 439-441 http://www.uniprot.org/uniprot/Q9N2J8 denotes TM
T78 499-501 http://www.uniprot.org/uniprot/Q9N2J8 denotes TM
T79 857-859 http://www.uniprot.org/uniprot/Q9N2J8 denotes TM
T80 1102-1104 http://www.uniprot.org/uniprot/Q9N2J8 denotes TM
T81 439-441 http://www.uniprot.org/uniprot/Q9N2K0 denotes TM
T82 499-501 http://www.uniprot.org/uniprot/Q9N2K0 denotes TM
T83 857-859 http://www.uniprot.org/uniprot/Q9N2K0 denotes TM
T84 1102-1104 http://www.uniprot.org/uniprot/Q9N2K0 denotes TM

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 439-441 http://www.uniprot.org/uniprot/P15306 denotes TM
T2 499-501 http://www.uniprot.org/uniprot/P15306 denotes TM
T3 857-859 http://www.uniprot.org/uniprot/P15306 denotes TM
T4 1102-1104 http://www.uniprot.org/uniprot/P15306 denotes TM
T5 439-441 http://www.uniprot.org/uniprot/Q811M9 denotes TM
T6 499-501 http://www.uniprot.org/uniprot/Q811M9 denotes TM
T7 857-859 http://www.uniprot.org/uniprot/Q811M9 denotes TM
T8 1102-1104 http://www.uniprot.org/uniprot/Q811M9 denotes TM

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 387-392 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T2 880-885 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 1009-1014 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 0-13 http://purl.obolibrary.org/obo/GO_0070085 denotes Glycosylation
T2 402-415 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T3 1061-1074 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T4 1164-1177 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T5 192-214 http://purl.obolibrary.org/obo/GO_0045065 denotes cytotoxic T lymphocyte
T6 192-214 http://purl.obolibrary.org/obo/GO_1902483 denotes cytotoxic T lymphocyte
T7 192-214 http://purl.obolibrary.org/obo/GO_0001913 denotes cytotoxic T lymphocyte
T8 192-214 http://purl.obolibrary.org/obo/GO_0043316 denotes cytotoxic T lymphocyte
T9 230-239 http://purl.obolibrary.org/obo/GO_0019835 denotes cytolysis
T10 539-561 http://purl.obolibrary.org/obo/GO_0016051 denotes carbohydrate formation
T11 552-561 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T12 1155-1177 http://purl.obolibrary.org/obo/GO_0006487 denotes N-linked glycosylation
T13 1227-1247 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen presentation

GO-CC

Id Subject Object Predicate Lexical cue
T1 149-153 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 775-779 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 387-392 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 880-885 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5 1009-1014 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 352-357 http://purl.obolibrary.org/obo/MAT_0000239 denotes stems

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 352-357 Body_part denotes stems http://purl.obolibrary.org/obo/MAT_0000239

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 99-112 Body_part denotes T lymphocytes http://purl.obolibrary.org/obo/CL_0000084
T2 202-214 Body_part denotes T lymphocyte http://purl.obolibrary.org/obo/CL_0000084
T3 956-962 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 142-153 Phenotype denotes target cell HP:0034280
T2 380-392 Phenotype denotes target cells HP:0034280
T3 768-779 Phenotype denotes target cell HP:0034280
T4 873-885 Phenotype denotes target cells HP:0034280
T5 1002-1014 Phenotype denotes target cells HP:0034280

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 89-112 Cell denotes cytotoxic T lymphocytes http://purl.obolibrary.org/obo/CL:0000794|http://purl.obolibrary.org/obo/CL:0000910
T3 192-214 Cell denotes cytotoxic T lymphocyte http://purl.obolibrary.org/obo/CL:0000794|http://purl.obolibrary.org/obo/CL:0000910
T5 202-214 Cell denotes T lymphocyte http://purl.obolibrary.org/obo/CL:0000084
T6 204-214 Cell denotes lymphocyte http://purl.obolibrary.org/obo/CL:0000542
T7 216-219 Cell denotes CTL http://purl.obolibrary.org/obo/CL:0000794
T8 956-962 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084