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sentences

Id Subject Object Predicate Lexical cue
T1 0-163 Sentence denotes The related molecular chaperones calnexin and calreticulin differentially associate with nascent T cell antigen receptor proteins within the endoplasmic reticulum.
T2 164-455 Sentence denotes Assembly of the multisubunit T cell antigen receptor (TCR) complex is an intricate process requiring coordinated regulation of at least six different gene products (alpha, beta, gamma, delta, epsilon, and zeta) and the ordered pairing of partner chains within the endoplasmic reticulum (ER).
T3 456-776 Sentence denotes To date, two proteins have been implicated as functioning as molecular chaperones in the assembly of nascent TCR proteins: calnexin, a resident ER transmembrane protein, which associates with all TCR components except zeta, and T cell receptor-associated protein, which selectively associates with CD3gammaepsilon pairs.
T4 777-939 Sentence denotes In this study, we examined the association of calreticulin, a soluble protein with significant sequence homology to calnexin, with newly synthesized TCR proteins.
T5 940-1227 Sentence denotes Analogous to calnexin, processing of glycan chains by glucosidase enzymes was required for initial association of TCRalpha and -beta proteins with calreticulin; however, several major differences were noted regarding interaction of calnexin and calreticulin chaperones with TCR proteins.
T6 1228-1526 Sentence denotes First, TCRalpha and -beta proteins showed prolonged association with calnexin molecules compared with calreticulin; interaction of TCRalpha proteins with calreticulin was particularly transient, with most calreticulin-TCRalpha protein complexes dissociating within 15 min of their initial assembly.
T7 1527-1759 Sentence denotes Second, we found that, unlike calnexin, which associated with clonotypic TCRalpha and -beta proteins and invariant CD3delta and -epsilon polypeptides, calreticulin associated specifically with clonotypic TCRalpha and -beta proteins.
T8 1760-1994 Sentence denotes These studies identify calreticulin as a molecular chaperone for nascent clonotypic TCRalpha and -beta proteins and demonstrate that calreticulin and calnexin differentially associate with newly synthesized TCR proteins within the ER.
T1 0-163 Sentence denotes The related molecular chaperones calnexin and calreticulin differentially associate with nascent T cell antigen receptor proteins within the endoplasmic reticulum.
T2 164-455 Sentence denotes Assembly of the multisubunit T cell antigen receptor (TCR) complex is an intricate process requiring coordinated regulation of at least six different gene products (alpha, beta, gamma, delta, epsilon, and zeta) and the ordered pairing of partner chains within the endoplasmic reticulum (ER).
T3 456-776 Sentence denotes To date, two proteins have been implicated as functioning as molecular chaperones in the assembly of nascent TCR proteins: calnexin, a resident ER transmembrane protein, which associates with all TCR components except zeta, and T cell receptor-associated protein, which selectively associates with CD3gammaepsilon pairs.
T4 777-939 Sentence denotes In this study, we examined the association of calreticulin, a soluble protein with significant sequence homology to calnexin, with newly synthesized TCR proteins.
T5 940-1227 Sentence denotes Analogous to calnexin, processing of glycan chains by glucosidase enzymes was required for initial association of TCRalpha and -beta proteins with calreticulin; however, several major differences were noted regarding interaction of calnexin and calreticulin chaperones with TCR proteins.
T6 1228-1526 Sentence denotes First, TCRalpha and -beta proteins showed prolonged association with calnexin molecules compared with calreticulin; interaction of TCRalpha proteins with calreticulin was particularly transient, with most calreticulin-TCRalpha protein complexes dissociating within 15 min of their initial assembly.
T7 1527-1759 Sentence denotes Second, we found that, unlike calnexin, which associated with clonotypic TCRalpha and -beta proteins and invariant CD3delta and -epsilon polypeptides, calreticulin associated specifically with clonotypic TCRalpha and -beta proteins.
T8 1760-1994 Sentence denotes These studies identify calreticulin as a molecular chaperone for nascent clonotypic TCRalpha and -beta proteins and demonstrate that calreticulin and calnexin differentially associate with newly synthesized TCR proteins within the ER.

bionlp-st-epi-2011-training

Id Subject Object Predicate Lexical cue
T1 33-41 Protein denotes calnexin
T2 46-58 Protein denotes calreticulin
T3 579-587 Protein denotes calnexin
T4 754-762 Protein denotes CD3gamma
T5 762-769 Protein denotes epsilon
T6 823-835 Protein denotes calreticulin
T7 893-901 Protein denotes calnexin
T8 953-961 Protein denotes calnexin
T9 1054-1062 Protein denotes TCRalpha
T10 1067-1072 Protein denotes -beta
T11 1087-1099 Protein denotes calreticulin
T12 1172-1180 Protein denotes calnexin
T13 1185-1197 Protein denotes calreticulin
T14 1235-1243 Protein denotes TCRalpha
T15 1248-1253 Protein denotes -beta
T16 1297-1305 Protein denotes calnexin
T17 1330-1342 Protein denotes calreticulin
T18 1359-1367 Protein denotes TCRalpha
T19 1382-1394 Protein denotes calreticulin
T20 1433-1445 Protein denotes calreticulin
T21 1446-1454 Protein denotes TCRalpha
T22 1557-1565 Protein denotes calnexin
T23 1600-1608 Protein denotes TCRalpha
T24 1613-1618 Protein denotes -beta
T25 1642-1650 Protein denotes CD3delta
T26 1655-1663 Protein denotes -epsilon
T27 1678-1690 Protein denotes calreticulin
T28 1731-1739 Protein denotes TCRalpha
T29 1744-1749 Protein denotes -beta
T30 1783-1795 Protein denotes calreticulin
T31 1844-1852 Protein denotes TCRalpha
T32 1857-1862 Protein denotes -beta
T33 1893-1905 Protein denotes calreticulin
T34 1910-1918 Protein denotes calnexin

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 97-103 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T2 153-162 Body_part denotes reticulum http://purl.obolibrary.org/obo/UBERON_0007361
T3 193-199 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T4 440-449 Body_part denotes reticulum http://purl.obolibrary.org/obo/UBERON_0007361
T5 603-616 Body_part denotes transmembrane http://purl.obolibrary.org/obo/GO_0016020
T6 684-690 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 97-103 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T2 193-199 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T3 349-354 Cell denotes delta http://purl.obolibrary.org/obo/CL:0004124
T4 356-363 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T5 684-690 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T6 1656-1663 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025