PubMed:8752218
Annnotations
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 33-41 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
| T2 | 599-607 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
| T3 | 962-970 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 33-41 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
| T2 | 599-607 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
| T3 | 962-970 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-145 | Sentence | denotes | The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. |
| T2 | 146-340 | Sentence | denotes | alpha(1,3)Fucosylated oligosaccharides represent components of leukocyte counterreceptors for E- and P-selectins and of L-selectin ligands expressed by lymph node high endothelial venules (HEV). |
| T3 | 341-525 | Sentence | denotes | The identity of the alpha(1,3)fucosyltransferase(s) required for their expression has been uncertain, as has a requirement for alpha(1,3)fucosylation in HEV L-selectin ligand activity. |
| T4 | 526-761 | Sentence | denotes | We demonstrate here that mice deficient in alpha(1,3) fucosyltransferase Fuc-TVII exhibit a leukocyte adhesion deficiency characterized by absent leukocyte E- and P-selectin ligand activity and deficient HEV L-selectin ligand activity. |
| T5 | 762-908 | Sentence | denotes | Selectin ligand deficiency is distinguished by blood leukocytosis, impaired leukocyte extravasation in inflammation, and faulty lymphocyte homing. |
| T6 | 909-1099 | Sentence | denotes | These observations demonstrate an essential role for Fuc-TVII in E-, P-, and L-selectin ligand biosynthesis and imply that this locus can control leukocyte trafficking in health and disease. |
| T1 | 0-145 | Sentence | denotes | The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. |
| T2 | 146-340 | Sentence | denotes | alpha(1,3)Fucosylated oligosaccharides represent components of leukocyte counterreceptors for E- and P-selectins and of L-selectin ligands expressed by lymph node high endothelial venules (HEV). |
| T3 | 341-525 | Sentence | denotes | The identity of the alpha(1,3)fucosyltransferase(s) required for their expression has been uncertain, as has a requirement for alpha(1,3)fucosylation in HEV L-selectin ligand activity. |
| T4 | 526-761 | Sentence | denotes | We demonstrate here that mice deficient in alpha(1,3) fucosyltransferase Fuc-TVII exhibit a leukocyte adhesion deficiency characterized by absent leukocyte E- and P-selectin ligand activity and deficient HEV L-selectin ligand activity. |
| T5 | 762-908 | Sentence | denotes | Selectin ligand deficiency is distinguished by blood leukocytosis, impaired leukocyte extravasation in inflammation, and faulty lymphocyte homing. |
| T6 | 909-1099 | Sentence | denotes | These observations demonstrate an essential role for Fuc-TVII in E-, P-, and L-selectin ligand biosynthesis and imply that this locus can control leukocyte trafficking in health and disease. |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 33-41 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
| PD-GlycoGenes20190927-B_T2 | 423-426 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
| PD-GlycoGenes20190927-B_T3 | 446-449 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
| PD-GlycoGenes20190927-B_T4 | 599-607 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
| PD-GlycoGenes20190927-B_T5 | 962-970 | https://acgg.asia/db/ggdb/info/gg007 | denotes | Fuc-TVII |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 618-647 | Disease | denotes | leukocyte adhesion deficiency | http://purl.obolibrary.org/obo/MONDO_0017570 |
| T2 | 865-877 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 298-308 | Body_part | denotes | lymph node | http://purl.obolibrary.org/obo/MAT_0000197|http://purl.obolibrary.org/obo/MAT_0000442 |
| T3 | 809-814 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 551-555 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 51-60 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
| T2 | 209-218 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
| T3 | 298-333 | Body_part | denotes | lymph node high endothelial venules | http://purl.obolibrary.org/obo/UBERON_8410038 |
| T4 | 335-338 | Body_part | denotes | HEV | http://purl.obolibrary.org/obo/UBERON_8410037 |
| T5 | 494-497 | Body_part | denotes | HEV | http://purl.obolibrary.org/obo/UBERON_8410037 |
| T6 | 618-627 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
| T7 | 672-681 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
| T8 | 730-733 | Body_part | denotes | HEV | http://purl.obolibrary.org/obo/UBERON_8410037 |
| T9 | 809-814 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T10 | 838-847 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
| T11 | 890-900 | Body_part | denotes | lymphocyte | http://purl.obolibrary.org/obo/CL_0000542 |
| T12 | 1055-1064 | Body_part | denotes | leukocyte | http://purl.obolibrary.org/obo/CL_0000738 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 815-827 | Phenotype | denotes | leukocytosis | HP:0001974 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 51-60 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
| T2 | 209-218 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
| T3 | 618-627 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
| T4 | 672-681 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
| T5 | 838-847 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |
| T6 | 890-900 | Cell | denotes | lymphocyte | http://purl.obolibrary.org/obo/CL:0000542 |
| T7 | 1055-1064 | Cell | denotes | leukocyte | http://purl.obolibrary.org/obo/CL:0000738 |