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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-83 Sentence denotes Involvement of tyrosine phosphorylation in endothelial adhesion molecule induction.
T2 84-412 Sentence denotes Induction of endothelial adhesion molecules by the cytokine tumor necrosis factor-alpha (TNF) can occur independently of protein kinase C and activation of a protein tyrosine kinase (PTK) has recently been implicated in the upregulation of vascular cell adhesion molecule 1 (VCAM-1) by interleukin-4 (IL-4) on endothelial cells.
T3 413-620 Sentence denotes We demonstrate that the PTK inhibitors herbimycin A or genistein suppress induction of endothelial VCAM-1 and E-selectin, as well as subsequent monocytic cell adhesion to endothelial cells stimulated by TNF.
T4 621-825 Sentence denotes Inhibition studies indicate that specific tyrosine phosphorylation following PTK activation is involved in the mobilization of the transcription factor, nuclear factor kappa B, and VCAM-1 mRNA expression.
T5 826-976 Sentence denotes This may have implications for pathophysiological conditions that involve the upregulation of these molecules (e.g. inflammation and atherosclerosis).
T1 0-83 Sentence denotes Involvement of tyrosine phosphorylation in endothelial adhesion molecule induction.
T2 84-412 Sentence denotes Induction of endothelial adhesion molecules by the cytokine tumor necrosis factor-alpha (TNF) can occur independently of protein kinase C and activation of a protein tyrosine kinase (PTK) has recently been implicated in the upregulation of vascular cell adhesion molecule 1 (VCAM-1) by interleukin-4 (IL-4) on endothelial cells.
T3 413-620 Sentence denotes We demonstrate that the PTK inhibitors herbimycin A or genistein suppress induction of endothelial VCAM-1 and E-selectin, as well as subsequent monocytic cell adhesion to endothelial cells stimulated by TNF.
T4 621-825 Sentence denotes Inhibition studies indicate that specific tyrosine phosphorylation following PTK activation is involved in the mobilization of the transcription factor, nuclear factor kappa B, and VCAM-1 mRNA expression.
T5 826-976 Sentence denotes This may have implications for pathophysiological conditions that involve the upregulation of these molecules (e.g. inflammation and atherosclerosis).

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 43-72 protein denotes endothelial adhesion molecule
T2 97-127 protein denotes endothelial adhesion molecules
T3 135-143 protein denotes cytokine
T4 144-171 protein denotes tumor necrosis factor-alpha
T5 173-176 protein denotes TNF
T6 205-221 protein denotes protein kinase C
T7 242-265 protein denotes protein tyrosine kinase
T8 267-270 protein denotes PTK
T9 324-357 protein denotes vascular cell adhesion molecule 1
T10 359-365 protein denotes VCAM-1
T11 370-383 protein denotes interleukin-4
T12 385-389 protein denotes IL-4
T13 394-411 cell_type denotes endothelial cells
T14 437-440 protein denotes PTK
T15 512-518 protein denotes VCAM-1
T16 523-533 protein denotes E-selectin
T17 584-601 cell_type denotes endothelial cells
T18 616-619 protein denotes TNF
T19 698-701 protein denotes PTK
T20 752-772 protein denotes transcription factor
T21 774-796 protein denotes nuclear factor kappa B
T22 802-813 RNA denotes VCAM-1 mRNA

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 43-82 NP denotes endothelial adhesion molecule induction
C2 84-127 NP denotes Induction of endothelial adhesion molecules
C3 131-177 NP denotes the cytokine tumor necrosis factor-alpha (TNF)
C4 240-271 NP denotes a protein tyrosine kinase (PTK)
C7 226-271 NP denotes activation of a protein tyrosine kinase (PTK)
C6 616-619 NP denotes TNF
C8 698-712 NP denotes PTK activation
C9 748-772 NP denotes the transcription factor
C10 774-796 NP denotes nuclear factor kappa B
C11 857-886 NP denotes pathophysiological conditions
C12 887-891 NP denotes that
R1 C2 C1 coref-ident Induction of endothelial adhesion molecules,endothelial adhesion molecule induction
R2 C6 C3 coref-ident TNF,the cytokine tumor necrosis factor-alpha (TNF)
R3 C8 C7 coref-ident PTK activation,activation of a protein tyrosine kinase (PTK)
R4 C10 C9 coref-appos nuclear factor kappa B,the transcription factor
R5 C12 C11 coref-relat that,pathophysiological conditions

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-83 Sentence denotes Involvement of tyrosine phosphorylation in endothelial adhesion molecule induction.
S2 84-412 Sentence denotes Induction of endothelial adhesion molecules by the cytokine tumor necrosis factor-alpha (TNF) can occur independently of protein kinase C and activation of a protein tyrosine kinase (PTK) has recently been implicated in the upregulation of vascular cell adhesion molecule 1 (VCAM-1) by interleukin-4 (IL-4) on endothelial cells.
S3 413-620 Sentence denotes We demonstrate that the PTK inhibitors herbimycin A or genistein suppress induction of endothelial VCAM-1 and E-selectin, as well as subsequent monocytic cell adhesion to endothelial cells stimulated by TNF.
S4 621-825 Sentence denotes Inhibition studies indicate that specific tyrosine phosphorylation following PTK activation is involved in the mobilization of the transcription factor, nuclear factor kappa B, and VCAM-1 mRNA expression.
S5 826-976 Sentence denotes This may have implications for pathophysiological conditions that involve the upregulation of these molecules (e.g. inflammation and atherosclerosis).

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 15-23 amino_acid_monomer denotes tyrosine
T2 43-72 protein_family_or_group denotes endothelial adhesion molecule
T3 97-127 protein_family_or_group denotes endothelial adhesion molecules
T4 135-143 protein_family_or_group denotes cytokine
T5 144-171 protein_molecule denotes tumor necrosis factor-alpha
T6 173-176 protein_molecule denotes TNF
T7 205-221 protein_molecule denotes protein kinase C
T8 242-249 protein_family_or_group denotes protein
T9 250-258 amino_acid_monomer denotes tyrosine
T10 267-270 protein_family_or_group denotes PTK
T11 324-357 protein_molecule denotes vascular cell adhesion molecule 1
T12 359-365 protein_molecule denotes VCAM-1
T13 370-383 protein_molecule denotes interleukin-4
T14 385-389 protein_molecule denotes IL-4
T15 394-411 cell_type denotes endothelial cells
T16 437-440 protein_family_or_group denotes PTK
T17 452-464 other_organic_compound denotes herbimycin A
T18 468-477 other_organic_compound denotes genistein
T19 512-518 protein_molecule denotes VCAM-1
T20 523-533 protein_molecule denotes E-selectin
T21 557-580 other_name denotes monocytic cell adhesion
T22 584-601 cell_type denotes endothelial cells
T23 616-619 protein_molecule denotes TNF
T24 663-671 amino_acid_monomer denotes tyrosine
T25 698-701 protein_family_or_group denotes PTK
T26 752-772 protein_family_or_group denotes transcription factor
T27 774-796 protein_complex denotes nuclear factor kappa B
T28 802-808 protein_molecule denotes VCAM-1
T29 857-886 other_name denotes pathophysiological conditions
T30 942-954 other_name denotes inflammation
T31 959-974 other_name denotes atherosclerosis