PubMed:8720079
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 72-79 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T2 | 72-79 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T3 | 1227-1234 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T4 | 1227-1234 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T5 | 1299-1306 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T6 | 1299-1306 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T7 | 1439-1446 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T8 | 1439-1446 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 72-79 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T3 | 1227-1234 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T5 | 1299-1306 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
| T7 | 1439-1446 | Glycan_Motif | denotes | heparin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 791-796 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-152 | Sentence | denotes | Identification of O-sulphate substituents on D-glucuronic acid units in heparin-related glycosaminoglycans using novel synthetic disaccharide standards. |
| TextSentencer_T2 | 153-555 | Sentence | denotes | The two disaccharides, methyl 4-O-(2-O-sulpho-beta-D-glucopyranosyl-uronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside and methyl 4-O-(3-O-sulpho-beta-D-glucopyranosyluronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside, were prepared by de novo synthesis, and converted to the corresponding 2,5-anhydro-D-[1-3H]mannitol derivatives by deamination with nitrous acid followed by reduction with NaB3H4. |
| TextSentencer_T3 | 556-797 | Sentence | denotes | The resultant labelled products were used as standards in the identification, by anion-exchange high-performance liquid chromatography (HPLC), of disaccharides generated by HNO2/NaB3H4 treatment of heparan sulphate isolated from human brain. |
| TextSentencer_T4 | 798-927 | Sentence | denotes | The two standards, containing 2-O- and 3-O-sulphated glucuronic acid, respectively, were clearly separated by the HPLC procedure. |
| TextSentencer_T5 | 928-1139 | Sentence | denotes | Comparison with the deamination products derived from heparan sulphate showed that the mono-O-sulphated disaccharide species containing a sulphated glucuronic acid unit co-eluted with the 2-O-sulphated standard. |
| TextSentencer_T6 | 1140-1269 | Sentence | denotes | The corresponding component isolated from other heparan sulphate preparations, or from heparin, also eluted at the same position. |
| TextSentencer_T7 | 1270-1390 | Sentence | denotes | No disaccharide derived from heparin or heparan sulphate appeared at the elution position of the 3-O-sulphated standard. |
| TextSentencer_T8 | 1391-1554 | Sentence | denotes | It is concluded that D-glucuronic acid units in heparin-related glycosaminoglycans may be sulphated at C2, whereas no evidence has been found for sulphation at C3. |
| TextSentencer_T9 | 1555-1808 | Sentence | denotes | By contrast, analysis of mono-O-sulphated disaccharides derived from a chemically sulphated, bacterial capsular polysaccharide (generated by Escherichia coli K5) clearly demonstrated the occurrence of O-sulphate groups at C-3 of D-glucuronic acid units. |
| T1 | 0-152 | Sentence | denotes | Identification of O-sulphate substituents on D-glucuronic acid units in heparin-related glycosaminoglycans using novel synthetic disaccharide standards. |
| T2 | 153-555 | Sentence | denotes | The two disaccharides, methyl 4-O-(2-O-sulpho-beta-D-glucopyranosyl-uronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside and methyl 4-O-(3-O-sulpho-beta-D-glucopyranosyluronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside, were prepared by de novo synthesis, and converted to the corresponding 2,5-anhydro-D-[1-3H]mannitol derivatives by deamination with nitrous acid followed by reduction with NaB3H4. |
| T3 | 556-797 | Sentence | denotes | The resultant labelled products were used as standards in the identification, by anion-exchange high-performance liquid chromatography (HPLC), of disaccharides generated by HNO2/NaB3H4 treatment of heparan sulphate isolated from human brain. |
| T4 | 798-927 | Sentence | denotes | The two standards, containing 2-O- and 3-O-sulphated glucuronic acid, respectively, were clearly separated by the HPLC procedure. |
| T5 | 928-1139 | Sentence | denotes | Comparison with the deamination products derived from heparan sulphate showed that the mono-O-sulphated disaccharide species containing a sulphated glucuronic acid unit co-eluted with the 2-O-sulphated standard. |
| T6 | 1140-1269 | Sentence | denotes | The corresponding component isolated from other heparan sulphate preparations, or from heparin, also eluted at the same position. |
| T7 | 1270-1390 | Sentence | denotes | No disaccharide derived from heparin or heparan sulphate appeared at the elution position of the 3-O-sulphated standard. |
| T8 | 1391-1554 | Sentence | denotes | It is concluded that D-glucuronic acid units in heparin-related glycosaminoglycans may be sulphated at C2, whereas no evidence has been found for sulphation at C3. |
| T9 | 1555-1808 | Sentence | denotes | By contrast, analysis of mono-O-sulphated disaccharides derived from a chemically sulphated, bacterial capsular polysaccharide (generated by Escherichia coli K5) clearly demonstrated the occurrence of O-sulphate groups at C-3 of D-glucuronic acid units. |
| T1 | 0-152 | Sentence | denotes | Identification of O-sulphate substituents on D-glucuronic acid units in heparin-related glycosaminoglycans using novel synthetic disaccharide standards. |
| T2 | 153-555 | Sentence | denotes | The two disaccharides, methyl 4-O-(2-O-sulpho-beta-D-glucopyranosyl-uronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside and methyl 4-O-(3-O-sulpho-beta-D-glucopyranosyluronic acid)-2-deoxy-2-amino-alpha-D-glucopyranoside, were prepared by de novo synthesis, and converted to the corresponding 2,5-anhydro-D-[1-3H]mannitol derivatives by deamination with nitrous acid followed by reduction with NaB3H4. |
| T3 | 556-797 | Sentence | denotes | The resultant labelled products were used as standards in the identification, by anion-exchange high-performance liquid chromatography (HPLC), of disaccharides generated by HNO2/NaB3H4 treatment of heparan sulphate isolated from human brain. |
| T4 | 798-927 | Sentence | denotes | The two standards, containing 2-O- and 3-O-sulphated glucuronic acid, respectively, were clearly separated by the HPLC procedure. |
| T5 | 928-1139 | Sentence | denotes | Comparison with the deamination products derived from heparan sulphate showed that the mono-O-sulphated disaccharide species containing a sulphated glucuronic acid unit co-eluted with the 2-O-sulphated standard. |
| T6 | 1140-1269 | Sentence | denotes | The corresponding component isolated from other heparan sulphate preparations, or from heparin, also eluted at the same position. |
| T7 | 1270-1390 | Sentence | denotes | No disaccharide derived from heparin or heparan sulphate appeared at the elution position of the 3-O-sulphated standard. |
| T8 | 1391-1554 | Sentence | denotes | It is concluded that D-glucuronic acid units in heparin-related glycosaminoglycans may be sulphated at C2, whereas no evidence has been found for sulphation at C3. |
| T9 | 1555-1808 | Sentence | denotes | By contrast, analysis of mono-O-sulphated disaccharides derived from a chemically sulphated, bacterial capsular polysaccharide (generated by Escherichia coli K5) clearly demonstrated the occurrence of O-sulphate groups at C-3 of D-glucuronic acid units. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 72-79 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T2 | 72-79 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T3 | 1227-1234 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T4 | 1227-1234 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T5 | 1299-1306 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T6 | 1299-1306 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
| T7 | 1439-1446 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
| T8 | 1439-1446 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
GlycoBiology-PACDB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 | denotes | Escherichia coli |
| _T2 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 | denotes | Escherichia coli |
| _T3 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 | denotes | Escherichia coli |
| _T4 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 | denotes | Escherichia coli |
| _T5 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 | denotes | Escherichia coli |
| _T6 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 | denotes | Escherichia coli |
| _T7 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 | denotes | Escherichia coli |
| _T8 | 1696-1712 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 | denotes | Escherichia coli |
| _T9 | 1696-1715 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC174,LEC426 | denotes | Escherichia coli K5 |
| _T10 | 1696-1715 | http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 | denotes | Escherichia coli K5 |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T7 | 129-141 | FMAID:196733 | denotes | disaccharide |
| _T1 | 47-62 | FMAID:196793 | denotes | glucuronic acid |
| _T2 | 47-62 | FMAID:82798 | denotes | glucuronic acid |
| _T3 | 72-79 | FMAID:82839 | denotes | heparin |
| _T4 | 72-79 | FMAID:167420 | denotes | heparin |
| _T5 | 88-106 | FMAID:167395 | denotes | glycosaminoglycans |
| _T6 | 88-106 | FMAID:63011 | denotes | glycosaminoglycans |
| _T8 | 129-141 | FMAID:82744 | denotes | disaccharide |
| _T9 | 161-174 | FMAID:196733 | denotes | disaccharides |
| _T10 | 161-174 | FMAID:82744 | denotes | disaccharides |
| _T11 | 669-675 | FMAID:85815 | denotes | liquid |
| _T12 | 702-715 | FMAID:82744 | denotes | disaccharides |
| _T13 | 702-715 | FMAID:196733 | denotes | disaccharides |
| _T14 | 754-761 | FMAID:67110 | denotes | heparan |
| _T15 | 754-761 | FMAID:165191 | denotes | heparan |
| _T16 | 754-770 | FMAID:63023 | denotes | heparan sulphate |
| _T17 | 754-770 | FMAID:167405 | denotes | heparan sulphate |
| _T18 | 791-796 | FMAID:146514 | denotes | brain |
| _T19 | 791-796 | FMAID:50801 | denotes | brain |
| _T20 | 851-866 | FMAID:196793 | denotes | glucuronic acid |
| _T21 | 851-866 | FMAID:82798 | denotes | glucuronic acid |
| _T22 | 982-989 | FMAID:67110 | denotes | heparan |
| _T23 | 982-989 | FMAID:165191 | denotes | heparan |
| _T24 | 982-998 | FMAID:63023 | denotes | heparan sulphate |
| _T25 | 982-998 | FMAID:167405 | denotes | heparan sulphate |
| _T26 | 1032-1044 | FMAID:196733 | denotes | disaccharide |
| _T27 | 1032-1044 | FMAID:82744 | denotes | disaccharide |
| _T28 | 1076-1091 | FMAID:82798 | denotes | glucuronic acid |
| _T29 | 1076-1091 | FMAID:196793 | denotes | glucuronic acid |
| _T30 | 1188-1195 | FMAID:67110 | denotes | heparan |
| _T31 | 1188-1195 | FMAID:165191 | denotes | heparan |
| _T32 | 1188-1204 | FMAID:167405 | denotes | heparan sulphate |
| _T33 | 1188-1204 | FMAID:63023 | denotes | heparan sulphate |
| _T34 | 1227-1234 | FMAID:167420 | denotes | heparin |
| _T35 | 1227-1234 | FMAID:82839 | denotes | heparin |
| _T36 | 1273-1285 | FMAID:82744 | denotes | disaccharide |
| _T37 | 1273-1285 | FMAID:196733 | denotes | disaccharide |
| _T38 | 1299-1306 | FMAID:82839 | denotes | heparin |
| _T39 | 1299-1306 | FMAID:167420 | denotes | heparin |
| _T40 | 1310-1317 | FMAID:67110 | denotes | heparan |
| _T41 | 1310-1317 | FMAID:165191 | denotes | heparan |
| _T42 | 1310-1326 | FMAID:167405 | denotes | heparan sulphate |
| _T43 | 1310-1326 | FMAID:63023 | denotes | heparan sulphate |
| _T44 | 1414-1429 | FMAID:82798 | denotes | glucuronic acid |
| _T45 | 1414-1429 | FMAID:196793 | denotes | glucuronic acid |
| _T46 | 1439-1446 | FMAID:167420 | denotes | heparin |
| _T47 | 1439-1446 | FMAID:82839 | denotes | heparin |
| _T48 | 1455-1473 | FMAID:167395 | denotes | glycosaminoglycans |
| _T49 | 1455-1473 | FMAID:63011 | denotes | glycosaminoglycans |
| _T50 | 1494-1496 | FMAID:63494 | denotes | C2 |
| _T51 | 1494-1496 | FMAID:167719 | denotes | C2 |
| _T52 | 1551-1553 | FMAID:63496 | denotes | C3 |
| _T53 | 1551-1553 | FMAID:167721 | denotes | C3 |
| _T54 | 1597-1610 | FMAID:196733 | denotes | disaccharides |
| _T55 | 1597-1610 | FMAID:82744 | denotes | disaccharides |
| _T56 | 1667-1681 | FMAID:82785 | denotes | polysaccharide |
| _T57 | 1667-1681 | FMAID:196779 | denotes | polysaccharide |
| _T58 | 1667-1681 | FMAID:82746 | denotes | polysaccharide |
| _T59 | 1667-1681 | FMAID:196735 | denotes | polysaccharide |
| _T60 | 1786-1801 | FMAID:82798 | denotes | glucuronic acid |
| _T61 | 1786-1801 | FMAID:196793 | denotes | glucuronic acid |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1494-1496 | http://www.uniprot.org/uniprot/P06681 | denotes | C2 |
| T2 | 1551-1553 | http://www.uniprot.org/uniprot/P01024 | denotes | C3 |
| T3 | 1713-1715 | http://www.uniprot.org/uniprot/P13647 | denotes | K5 |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1494-1496 | http://www.uniprot.org/uniprot/P21180 | denotes | C2 |
| T2 | 1551-1553 | http://www.uniprot.org/uniprot/P01027 | denotes | C3 |
| T3 | 1713-1715 | http://www.uniprot.org/uniprot/Q922U2 | denotes | K5 |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 80-87 | http://purl.bioontology.org/ontology/NCBITAXON/353209 | denotes | related |
| T2 | 199-203 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T3 | 199-203 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T4 | 301-305 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T5 | 301-305 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T6 | 1097-1099 | http://purl.bioontology.org/ontology/NCBITAXON/13893 | denotes | co |
| T7 | 1447-1454 | http://purl.bioontology.org/ontology/NCBITAXON/353209 | denotes | related |
| T8 | 1696-1707 | http://purl.bioontology.org/ontology/NCBITAXON/561 | denotes | Escherichia |
| T9 | 1767-1773 | http://purl.bioontology.org/ontology/STY/T096 | denotes | groups |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 20-28 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphate |
| T2 | 762-770 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphate |
| T3 | 990-998 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphate |
| T4 | 1196-1204 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphate |
| T5 | 1318-1326 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphate |
| T6 | 841-850 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphated |
| T7 | 1022-1031 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphated |
| T8 | 1066-1075 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphated |
| T9 | 1120-1129 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphated |
| T10 | 1371-1380 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphated |
| T11 | 1481-1490 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphated |
| T12 | 1587-1596 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphated |
| T13 | 1537-1547 | http://purl.obolibrary.org/obo/GO_0051923 | denotes | sulphation |
| T14 | 176-182 | http://purl.obolibrary.org/obo/GO_0032259 | denotes | methyl |
| T15 | 278-284 | http://purl.obolibrary.org/obo/GO_0032259 | denotes | methyl |
| T16 | 401-410 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T17 | 643-651 | http://purl.obolibrary.org/obo/GO_0015297 | denotes | exchange |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 791-796 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 791-796 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 72-79 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T2 | 1227-1234 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T3 | 1299-1306 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
| T4 | 1439-1446 | http://rdf.glycoinfo.org/glycan/G54161DR | denotes | heparin |
GlycoBiology-Epitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoEpitope-B_T1 | 570-578 | id | denotes | labelled |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 791-796 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 791-796 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 785-790 | OrganismTaxon | denotes | human | 9606 |
| T2 | 1696-1712 | OrganismTaxon | denotes | Escherichia coli | 562 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 791-796 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |