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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-107 Sentence denotes Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes.
T2 108-248 Sentence denotes Eosinophils and neutrophils are closely related, terminally differentiated cells that in vitro undergo constitutive cell death by apoptosis.
T3 249-349 Sentence denotes The onset of apoptosis in both cell types can be delayed by hemopoietins and inflammatory mediators.
T4 350-608 Sentence denotes Although there have been a number of reports demonstrating that glucocorticoids (in particular dexamethasone) antagonize the eosinophil life-prolonging effects of hemopoietins, direct effects of dexamethasone on eosinophil apoptosis have not been documented.
T5 609-817 Sentence denotes In this study we examined the direct effects of glucocorticoids on eosinophil and neutrophil apoptosis in light of their common therapeutic use as anti-inflammatory and anti-allergic/hypereosinophilic agents.
T6 818-890 Sentence denotes We found that treatment with dexamethasone induced eosinophil apoptosis.
T7 891-965 Sentence denotes In contrast, dexamethasone was a potent inhibitor of neutrophil apoptosis.
T8 966-1136 Sentence denotes The effect of dexamethasone on both cell types was mediated through the glucocorticoid receptor, i.e., it was abolished by the glucocorticoid receptor antagonist RU38486.
T9 1137-1458 Sentence denotes This is the first description of an agent that promotes eosinophil apoptosis while inhibiting neutrophil apoptosis, and thus presents a novel approach to the study of control of apoptosis in these closely related cell types as well as increases our understanding of the clinical action of glucocorticoids in inflammation.
T1 0-107 Sentence denotes Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes.
T2 108-248 Sentence denotes Eosinophils and neutrophils are closely related, terminally differentiated cells that in vitro undergo constitutive cell death by apoptosis.
T3 249-349 Sentence denotes The onset of apoptosis in both cell types can be delayed by hemopoietins and inflammatory mediators.
T4 350-608 Sentence denotes Although there have been a number of reports demonstrating that glucocorticoids (in particular dexamethasone) antagonize the eosinophil life-prolonging effects of hemopoietins, direct effects of dexamethasone on eosinophil apoptosis have not been documented.
T5 609-817 Sentence denotes In this study we examined the direct effects of glucocorticoids on eosinophil and neutrophil apoptosis in light of their common therapeutic use as anti-inflammatory and anti-allergic/hypereosinophilic agents.
T6 818-890 Sentence denotes We found that treatment with dexamethasone induced eosinophil apoptosis.
T7 891-965 Sentence denotes In contrast, dexamethasone was a potent inhibitor of neutrophil apoptosis.
T8 966-1136 Sentence denotes The effect of dexamethasone on both cell types was mediated through the glucocorticoid receptor, i.e., it was abolished by the glucocorticoid receptor antagonist RU38486.
T9 1137-1458 Sentence denotes This is the first description of an agent that promotes eosinophil apoptosis while inhibiting neutrophil apoptosis, and thus presents a novel approach to the study of control of apoptosis in these closely related cell types as well as increases our understanding of the clinical action of glucocorticoids in inflammation.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 64-106 cell_type denotes neutrophilic and eosinophilic granulocytes
T2 108-119 cell_type denotes Eosinophils
T3 124-135 cell_type denotes neutrophils
T4 157-188 cell_type denotes terminally differentiated cells
T5 309-321 protein denotes hemopoietins
T6 326-348 protein denotes inflammatory mediators
T7 513-525 protein denotes hemopoietins
T8 676-686 cell_type denotes eosinophil
T9 691-701 cell_type denotes neutrophil
T10 869-879 cell_type denotes eosinophil
T11 944-954 cell_type denotes neutrophil
T12 1038-1061 protein denotes glucocorticoid receptor
T13 1093-1116 protein denotes glucocorticoid receptor
T14 1193-1203 cell_type denotes eosinophil
T15 1231-1241 cell_type denotes neutrophil

genia-medco-coref

Id Subject Object Predicate Lexical cue
C8 20-35 NP denotes glucocorticoids
C3 51-60 NP denotes apoptosis
C32 64-106 NP denotes neutrophilic and eosinophilic granulocytes
C6 108-135 NP denotes Eosinophils and neutrophils
C1 183-188 NP denotes cells
C2 189-193 NP denotes that
C4 238-247 NP denotes apoptosis
C5 262-271 NP denotes apoptosis
C7 275-290 NP denotes both cell types
C10 309-321 NP denotes hemopoietins
C9 414-429 NP denotes glucocorticoids
C11 513-525 NP denotes hemopoietins
C12 562-582 NP denotes eosinophil apoptosis
C13 657-672 NP denotes glucocorticoids
C14 676-711 NP denotes eosinophil and neutrophil apoptosis
C15 724-729 NP denotes their
C16 847-860 NP denotes dexamethasone
C33 869-889 NP denotes eosinophil apoptosis
C17 904-917 NP denotes dexamethasone
C18 944-964 NP denotes neutrophil apoptosis
C19 980-993 NP denotes dexamethasone
C20 997-1012 NP denotes both cell types
C23 966-1012 NP denotes The effect of dexamethasone on both cell types
C22 1034-1061 NP denotes the glucocorticoid receptor
C24 1069-1071 NP denotes it
C21 1089-1135 NP denotes the glucocorticoid receptor antagonist RU38486
C25 1170-1178 NP denotes an agent
C26 1179-1183 NP denotes that
C27 1193-1213 NP denotes eosinophil apoptosis
C28 1231-1251 NP denotes neutrophil apoptosis
C29 1315-1324 NP denotes apoptosis
C30 1328-1360 NP denotes these closely related cell types
C31 1426-1441 NP denotes glucocorticoids
R1 C6 C32 coref-xxx Eosinophils and neutrophils,neutrophilic and eosinophilic granulocytes
R2 C2 C1 coref-relat that,cells
R3 C4 C3 coref-ident apoptosis,apoptosis
R4 C5 C4 coref-ident apoptosis,apoptosis
R5 C7 C6 coref-ident both cell types,Eosinophils and neutrophils
R6 C9 C8 coref-ident glucocorticoids,glucocorticoids
R7 C11 C10 coref-ident hemopoietins,hemopoietins
R8 C13 C9 coref-ident glucocorticoids,glucocorticoids
R9 C14 C12 coref-whole-part eosinophil and neutrophil apoptosis,eosinophil apoptosis
R10 C15 C14 coref-pron their,eosinophil and neutrophil apoptosis
R11 C33 C14 coref-part-whole eosinophil apoptosis,eosinophil and neutrophil apoptosis
R12 C17 C16 coref-ident dexamethasone,dexamethasone
R13 C18 C14 coref-part-whole neutrophil apoptosis,eosinophil and neutrophil apoptosis
R14 C19 C17 coref-ident dexamethasone,dexamethasone
R15 C20 C6 coref-ident both cell types,Eosinophils and neutrophils
R16 C24 C23 coref-pron it,The effect of dexamethasone on both cell types
R17 C21 C22 coref-ident the glucocorticoid receptor antagonist RU38486,the glucocorticoid receptor
R18 C26 C25 coref-relat that,an agent
R19 C27 C12 coref-ident eosinophil apoptosis,eosinophil apoptosis
R20 C28 C18 coref-ident neutrophil apoptosis,neutrophil apoptosis
R21 C29 C5 coref-ident apoptosis,apoptosis
R22 C30 C6 coref-ident these closely related cell types,Eosinophils and neutrophils
R23 C31 C13 coref-ident glucocorticoids,glucocorticoids

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-107 Sentence denotes Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes.
S2 108-248 Sentence denotes Eosinophils and neutrophils are closely related, terminally differentiated cells that in vitro undergo constitutive cell death by apoptosis.
S3 249-349 Sentence denotes The onset of apoptosis in both cell types can be delayed by hemopoietins and inflammatory mediators.
S4 350-608 Sentence denotes Although there have been a number of reports demonstrating that glucocorticoids (in particular dexamethasone) antagonize the eosinophil life-prolonging effects of hemopoietins, direct effects of dexamethasone on eosinophil apoptosis have not been documented.
S5 609-817 Sentence denotes In this study we examined the direct effects of glucocorticoids on eosinophil and neutrophil apoptosis in light of their common therapeutic use as anti-inflammatory and anti-allergic/hypereosinophilic agents.
S6 818-890 Sentence denotes We found that treatment with dexamethasone induced eosinophil apoptosis.
S7 891-965 Sentence denotes In contrast, dexamethasone was a potent inhibitor of neutrophil apoptosis.
S8 966-1136 Sentence denotes The effect of dexamethasone on both cell types was mediated through the glucocorticoid receptor, i.e., it was abolished by the glucocorticoid receptor antagonist RU38486.
S9 1137-1458 Sentence denotes This is the first description of an agent that promotes eosinophil apoptosis while inhibiting neutrophil apoptosis, and thus presents a novel approach to the study of control of apoptosis in these closely related cell types as well as increases our understanding of the clinical action of glucocorticoids in inflammation.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 20-35 lipid denotes glucocorticoids
T2 51-60 other_name denotes apoptosis
T3 108-119 cell_type denotes Eosinophils
T4 124-135 cell_type denotes neutrophils
T5 157-188 cell_type denotes terminally differentiated cells
T6 211-234 other_name denotes constitutive cell death
T7 238-247 other_name denotes apoptosis
T8 262-271 other_name denotes apoptosis
T9 309-321 protein_family_or_group denotes hemopoietins
T10 326-348 protein_family_or_group denotes inflammatory mediators
T11 414-429 lipid denotes glucocorticoids
T12 445-458 lipid denotes dexamethasone
T13 475-509 other_name denotes eosinophil life-prolonging effects
T14 513-525 protein_family_or_group denotes hemopoietins
T15 545-558 lipid denotes dexamethasone
T16 562-572 other_name denotes eosinophil
T17 573-582 other_name denotes apoptosis
T18 657-672 lipid denotes glucocorticoids
T19 676-686 cell_type denotes eosinophil
T20 691-701 cell_type denotes neutrophil
T21 702-711 other_name denotes apoptosis
T22 847-860 lipid denotes dexamethasone
T23 869-879 cell_type denotes eosinophil
T24 880-889 other_name denotes apoptosis
T25 904-917 lipid denotes dexamethasone
T26 944-954 cell_type denotes neutrophil
T27 955-964 other_name denotes apoptosis
T28 980-993 lipid denotes dexamethasone
T29 1038-1061 protein_family_or_group denotes glucocorticoid receptor
T30 1093-1116 protein_family_or_group denotes glucocorticoid receptor
T31 1128-1135 other_organic_compound denotes RU38486
T32 1193-1203 cell_type denotes eosinophil
T33 1204-1213 other_name denotes apoptosis
T34 1231-1241 cell_type denotes neutrophil
T35 1242-1251 other_name denotes apoptosis
T36 1315-1324 other_name denotes apoptosis
T37 1426-1441 lipid denotes glucocorticoids
T38 1445-1457 other_name denotes inflammation