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PubMed:8621710 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-114 Sentence denotes Inactivation of raf-1 by a protein-tyrosine phosphatase stimulated by GTP and reconstituted by Galphai/o subunits.
T2 115-246 Sentence denotes A membrane-associated form of Raf-1 in v-Ras transformed NIH 3T3 cells can be inactivated by protein phosphatases regulated by GTP.
T3 247-529 Sentence denotes Herein, a distinct protein-tyrosine phosphatase (PTPase) in membrane preparations from v-Ras transformed NIH 3T3 cells was found to be activated by guanyl-5'-yl imidodiphosphate (GMPPNP) and was identified as an effector for pertussis toxin (PTx)-sensitive G-protein alpha subunits.
T4 530-597 Sentence denotes PTPase activation was blocked by prior treatment of cells with PTx.
T5 598-654 Sentence denotes PTPase activation by GTP, but not GMPPNP, was transient.
T6 655-773 Sentence denotes A GMPPNP-stimulated PTPase (PTPase-G) co-purified with Galphai/o subunits during Superose 6 and Mono Q chromatography.
T7 774-916 Sentence denotes PTPase-G activity in Superose 6 fractions from GDP-treated membranes was reconstituted by activated Galphai/o, but not G beta gamma, subunits.
T8 917-1094 Sentence denotes PTPase-G may contribute to GMPPNP-stimulated inactivation of Raf-1 in v-Ras cell membranes because Raf-1 inactivation was PTx-sensitive and PTPase-G inactivated exogenous Raf-1.
T1 0-114 Sentence denotes Inactivation of raf-1 by a protein-tyrosine phosphatase stimulated by GTP and reconstituted by Galphai/o subunits.
T2 115-246 Sentence denotes A membrane-associated form of Raf-1 in v-Ras transformed NIH 3T3 cells can be inactivated by protein phosphatases regulated by GTP.
T3 247-529 Sentence denotes Herein, a distinct protein-tyrosine phosphatase (PTPase) in membrane preparations from v-Ras transformed NIH 3T3 cells was found to be activated by guanyl-5'-yl imidodiphosphate (GMPPNP) and was identified as an effector for pertussis toxin (PTx)-sensitive G-protein alpha subunits.
T4 530-597 Sentence denotes PTPase activation was blocked by prior treatment of cells with PTx.
T5 598-654 Sentence denotes PTPase activation by GTP, but not GMPPNP, was transient.
T6 655-773 Sentence denotes A GMPPNP-stimulated PTPase (PTPase-G) co-purified with Galphai/o subunits during Superose 6 and Mono Q chromatography.
T7 774-916 Sentence denotes PTPase-G activity in Superose 6 fractions from GDP-treated membranes was reconstituted by activated Galphai/o, but not G beta gamma, subunits.
T8 917-1094 Sentence denotes PTPase-G may contribute to GMPPNP-stimulated inactivation of Raf-1 in v-Ras cell membranes because Raf-1 inactivation was PTx-sensitive and PTPase-G inactivated exogenous Raf-1.

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 472-481 Disease denotes pertussis http://purl.obolibrary.org/obo/MONDO_0005077

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 117-125 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T4 307-315 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T7 833-842 Body_part denotes membranes http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T10 993-1007 Body_part denotes cell membranes http://purl.obolibrary.org/obo/GO_0005886