PubMed:8570215
Annnotations
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 887-891 | gene:8115 | denotes | TCL1 |
| T1 | 925-928 | disease:C0004135 | denotes | A-T |
| T2 | 887-891 | gene:9623 | denotes | TCL1 |
| T3 | 925-928 | disease:C0004135 | denotes | A-T |
| T4 | 1453-1458 | gene:4068 | denotes | MTCP1 |
| T5 | 1400-1403 | disease:C0004135 | denotes | A-T |
| T6 | 1453-1458 | gene:100272147 | denotes | MTCP1 |
| T7 | 1381-1386 | disease:C2363142 | denotes | T-PLL |
| T8 | 1453-1458 | gene:4068 | denotes | MTCP1 |
| T9 | 1381-1386 | disease:C2363142 | denotes | T-PLL |
| T10 | 1453-1458 | gene:4515 | denotes | MTCP1 |
| T11 | 1381-1386 | disease:C2363142 | denotes | T-PLL |
| T12 | 1453-1458 | gene:100272147 | denotes | MTCP1 |
| T13 | 1400-1403 | disease:C0004135 | denotes | A-T |
| T14 | 1326-1331 | gene:4515 | denotes | MTCP1 |
| T15 | 1542-1545 | disease:C0004135 | denotes | A-T |
| T16 | 1453-1458 | gene:4515 | denotes | MTCP1 |
| T17 | 1400-1403 | disease:C0004135 | denotes | A-T |
| T18 | 1453-1458 | gene:100272147 | denotes | MTCP1 |
| T19 | 1542-1545 | disease:C0004135 | denotes | A-T |
| T20 | 1453-1458 | gene:4068 | denotes | MTCP1 |
| T21 | 1542-1545 | disease:C0004135 | denotes | A-T |
| T22 | 1453-1458 | gene:4515 | denotes | MTCP1 |
| T23 | 1542-1545 | disease:C0004135 | denotes | A-T |
| T24 | 1326-1331 | gene:4068 | denotes | MTCP1 |
| T25 | 1542-1545 | disease:C0004135 | denotes | A-T |
| T26 | 1326-1331 | gene:100272147 | denotes | MTCP1 |
| T27 | 1542-1545 | disease:C0004135 | denotes | A-T |
| R1 | T0 | T1 | associated_with | TCL1,A-T |
| R2 | T2 | T3 | associated_with | TCL1,A-T |
| R3 | T4 | T5 | associated_with | MTCP1,A-T |
| R4 | T6 | T7 | associated_with | MTCP1,T-PLL |
| R5 | T8 | T9 | associated_with | MTCP1,T-PLL |
| R6 | T10 | T11 | associated_with | MTCP1,T-PLL |
| R7 | T12 | T13 | associated_with | MTCP1,A-T |
| R8 | T14 | T15 | associated_with | MTCP1,A-T |
| R9 | T16 | T17 | associated_with | MTCP1,A-T |
| R10 | T18 | T19 | associated_with | MTCP1,A-T |
| R11 | T20 | T21 | associated_with | MTCP1,A-T |
| R12 | T22 | T23 | associated_with | MTCP1,A-T |
| R13 | T24 | T25 | associated_with | MTCP1,A-T |
| R14 | T26 | T27 | associated_with | MTCP1,A-T |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 25-38 | DNA | denotes | TCL1 oncogene |
| T2 | 74-85 | DNA | denotes | MTCP1/c6.1B |
| T3 | 104-125 | cell_type | denotes | non-leukaemic T cells |
| T4 | 270-295 | DNA | denotes | chromosome translocations |
| T5 | 328-346 | cell_type | denotes | peripheral T cells |
| T6 | 424-430 | cell_type | denotes | T cell |
| T7 | 444-463 | cell_type | denotes | translocation cells |
| T8 | 748-752 | protein | denotes | TCL1 |
| T9 | 757-762 | DNA | denotes | 14q32 |
| T10 | 771-796 | protein | denotes | c6.1B/MTCP1 A1 transcript |
| T11 | 798-805 | DNA | denotes | at-Xq28 |
| T12 | 887-891 | protein | denotes | TCL1 |
| T13 | 902-919 | cell_type | denotes | leukaemic T cells |
| T14 | 943-956 | DNA | denotes | chromosome 14 |
| T15 | 987-991 | protein | denotes | TCL1 |
| T16 | 1011-1035 | cell_type | denotes | preleukaemic clone cells |
| T17 | 1115-1119 | protein | denotes | TCL1 |
| T18 | 1292-1305 | RNA | denotes | B1 transcript |
| T19 | 1326-1331 | DNA | denotes | MTCP1 |
| T20 | 1453-1472 | RNA | denotes | MTCP1/A1 transcript |
| T21 | 1511-1538 | cell_type | denotes | tumour and non tumour cells |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 8570215-8#70#75#gene4515 | 1326-1331 | gene4515 | denotes | MTCP1 |
| 8570215-8#162#165#gene952 | 1418-1421 | gene952 | denotes | t(X |
| 8570215-8#197#202#gene4515 | 1453-1458 | gene4515 | denotes | MTCP1 |
| 8570215-8#125#130#diseaseC0023486 | 1381-1386 | diseaseC0023486 | denotes | T-PLL |
| 8570215-8#286#289#diseaseC0004135 | 1542-1545 | diseaseC0004135 | denotes | A-T |
| 8570215-8#298#301#diseaseC0004135 | 1554-1557 | diseaseC0004135 | denotes | A-T |
| 8570215-8#125#130#diseaseC0023486 | 1381-1386 | diseaseC0023486 | denotes | T-PLL |
| 8570215-8#286#289#diseaseC0004135 | 1542-1545 | diseaseC0004135 | denotes | A-T |
| 8570215-8#298#301#diseaseC0004135 | 1554-1557 | diseaseC0004135 | denotes | A-T |
| 8570215-8#286#289#diseaseC0004135 | 1542-1545 | diseaseC0004135 | denotes | A-T |
| 8570215-8#298#301#diseaseC0004135 | 1554-1557 | diseaseC0004135 | denotes | A-T |
| 70#75#gene4515125#130#diseaseC0023486 | 8570215-8#70#75#gene4515 | 8570215-8#125#130#diseaseC0023486 | associated_with | MTCP1,T-PLL |
| 70#75#gene4515286#289#diseaseC0004135 | 8570215-8#70#75#gene4515 | 8570215-8#286#289#diseaseC0004135 | associated_with | MTCP1,A-T |
| 70#75#gene4515298#301#diseaseC0004135 | 8570215-8#70#75#gene4515 | 8570215-8#298#301#diseaseC0004135 | associated_with | MTCP1,A-T |
| 70#75#gene4515125#130#diseaseC0023486 | 8570215-8#70#75#gene4515 | 8570215-8#125#130#diseaseC0023486 | associated_with | MTCP1,T-PLL |
| 70#75#gene4515286#289#diseaseC0004135 | 8570215-8#70#75#gene4515 | 8570215-8#286#289#diseaseC0004135 | associated_with | MTCP1,A-T |
| 70#75#gene4515298#301#diseaseC0004135 | 8570215-8#70#75#gene4515 | 8570215-8#298#301#diseaseC0004135 | associated_with | MTCP1,A-T |
| 70#75#gene4515286#289#diseaseC0004135 | 8570215-8#70#75#gene4515 | 8570215-8#286#289#diseaseC0004135 | associated_with | MTCP1,A-T |
| 70#75#gene4515298#301#diseaseC0004135 | 8570215-8#70#75#gene4515 | 8570215-8#298#301#diseaseC0004135 | associated_with | MTCP1,A-T |
| 162#165#gene952125#130#diseaseC0023486 | 8570215-8#162#165#gene952 | 8570215-8#125#130#diseaseC0023486 | associated_with | t(X,T-PLL |
| 162#165#gene952286#289#diseaseC0004135 | 8570215-8#162#165#gene952 | 8570215-8#286#289#diseaseC0004135 | associated_with | t(X,A-T |
| 162#165#gene952298#301#diseaseC0004135 | 8570215-8#162#165#gene952 | 8570215-8#298#301#diseaseC0004135 | associated_with | t(X,A-T |
| 162#165#gene952125#130#diseaseC0023486 | 8570215-8#162#165#gene952 | 8570215-8#125#130#diseaseC0023486 | associated_with | t(X,T-PLL |
| 162#165#gene952286#289#diseaseC0004135 | 8570215-8#162#165#gene952 | 8570215-8#286#289#diseaseC0004135 | associated_with | t(X,A-T |
| 162#165#gene952298#301#diseaseC0004135 | 8570215-8#162#165#gene952 | 8570215-8#298#301#diseaseC0004135 | associated_with | t(X,A-T |
| 162#165#gene952286#289#diseaseC0004135 | 8570215-8#162#165#gene952 | 8570215-8#286#289#diseaseC0004135 | associated_with | t(X,A-T |
| 162#165#gene952298#301#diseaseC0004135 | 8570215-8#162#165#gene952 | 8570215-8#298#301#diseaseC0004135 | associated_with | t(X,A-T |
| 197#202#gene4515125#130#diseaseC0023486 | 8570215-8#197#202#gene4515 | 8570215-8#125#130#diseaseC0023486 | associated_with | MTCP1,T-PLL |
| 197#202#gene4515286#289#diseaseC0004135 | 8570215-8#197#202#gene4515 | 8570215-8#286#289#diseaseC0004135 | associated_with | MTCP1,A-T |
| 197#202#gene4515298#301#diseaseC0004135 | 8570215-8#197#202#gene4515 | 8570215-8#298#301#diseaseC0004135 | associated_with | MTCP1,A-T |
| 197#202#gene4515125#130#diseaseC0023486 | 8570215-8#197#202#gene4515 | 8570215-8#125#130#diseaseC0023486 | associated_with | MTCP1,T-PLL |
| 197#202#gene4515286#289#diseaseC0004135 | 8570215-8#197#202#gene4515 | 8570215-8#286#289#diseaseC0004135 | associated_with | MTCP1,A-T |
| 197#202#gene4515298#301#diseaseC0004135 | 8570215-8#197#202#gene4515 | 8570215-8#298#301#diseaseC0004135 | associated_with | MTCP1,A-T |
| 197#202#gene4515286#289#diseaseC0004135 | 8570215-8#197#202#gene4515 | 8570215-8#286#289#diseaseC0004135 | associated_with | MTCP1,A-T |
| 197#202#gene4515298#301#diseaseC0004135 | 8570215-8#197#202#gene4515 | 8570215-8#298#301#diseaseC0004135 | associated_with | MTCP1,A-T |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-162 | Sentence | denotes | Expression of either the TCL1 oncogene, or transcripts from its homologue MTCP1/c6.1B, in leukaemic and non-leukaemic T cells from ataxia telangiectasia patients. |
| S2 | 163-438 | Sentence | denotes | Patients with the recessively inherited disorder ataxia telangiectasia (A-T) have a high level of specific chromosome translocations which can be easily observed in peripheral T cells and show a greatly increased predisposition to leukaemia/lymphoma, mainly of T cell origin. |
| S3 | 439-556 | Sentence | denotes | Some translocation cells proliferate into a large clone and may develop into T cell prolymphocytic leukaemia (T-PLL). |
| S4 | 557-678 | Sentence | denotes | By the time of diagnosis of T-PLL, the clone contains many more genetic changes in the form of additional translocations. |
| S5 | 679-853 | Sentence | denotes | T-PLL is also seen in non-A-T individuals where expression of either TCL1 (at 14q32) or the c6.1B/MTCP1 A1 transcript (at-Xq28) has been demonstrated in just a few instances. |
| S6 | 854-972 | Sentence | denotes | We show here, that expression of TCL1 occurs in leukaemic T cells from A-T patients with chromosome 14 rearrangements. |
| S7 | 973-1095 | Sentence | denotes | Expression of TCL1 also occurs in the preleukaemic clone cells of A-T patients containing the primary translocation alone. |
| S8 | 1096-1255 | Sentence | denotes | Some expression of TCL1 could also be detected in randomly selected A-T patients without large cytogenetic clones and without any evidence of leukaemic change. |
| S9 | 1256-1570 | Sentence | denotes | We also show that expression of the B1 transcript from a second gene, MTCP1, occurred at a relatively high level only in two T-PLL tumours from A-T patients with t(X;14) translocations whereas the MTCP1/A1 transcript is much more widely expressed in both tumour and non tumour cells of A-T and non-A-T individuals. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 21-38 | NP | denotes | the TCL1 oncogene |
| C2 | 60-63 | NP | denotes | its |
| C3 | 163-244 | NP | denotes | Patients with the recessively inherited disorder ataxia telangiectasia (A-T) have |
| C4 | 245-295 | NP | denotes | a high level of specific chromosome translocations |
| C5 | 296-301 | NP | denotes | which |
| C6 | 481-494 | NP | denotes | a large clone |
| C7 | 516-555 | NP | denotes | T cell prolymphocytic leukaemia (T-PLL) |
| C8 | 585-590 | NP | denotes | T-PLL |
| C9 | 592-601 | NP | denotes | the clone |
| C10 | 679-684 | NP | denotes | T-PLL |
| C11 | 701-720 | NP | denotes | non-A-T individuals |
| C12 | 721-726 | NP | denotes | where |
| C13 | 748-752 | NP | denotes | TCL1 |
| C15 | 887-891 | NP | denotes | TCL1 |
| C14 | 873-891 | NP | denotes | expression of TCL1 |
| C16 | 925-937 | NP | denotes | A-T patients |
| C18 | 987-991 | NP | denotes | TCL1 |
| C17 | 973-991 | NP | denotes | Expression of TCL1 |
| C19 | 1039-1094 | NP | denotes | A-T patients containing the primary translocation alone |
| C20 | 1115-1119 | NP | denotes | TCL1 |
| C21 | 1311-1324 | NP | denotes | a second gene |
| C22 | 1326-1331 | NP | denotes | MTCP1 |
| C23 | 1400-1440 | NP | denotes | A-T patients with t(X;14) translocations |
| R1 | C2 | C1 | coref-pron | its,the TCL1 oncogene |
| R2 | C5 | C4 | coref-relat | which,a high level of specific chromosome translocations |
| R3 | C8 | C7 | coref-ident | T-PLL,T cell prolymphocytic leukaemia (T-PLL) |
| R4 | C9 | C6 | coref-ident | the clone,a large clone |
| R5 | C10 | C8 | coref-ident | T-PLL,T-PLL |
| R6 | C12 | C11 | coref-relat | where,non-A-T individuals |
| R7 | C15 | C13 | coref-ident | TCL1,TCL1 |
| R8 | C16 | C3 | coref-ident | A-T patients,Patients with the recessively inherited disorder ataxia telangiectasia (A-T) have |
| R9 | C18 | C15 | coref-ident | TCL1,TCL1 |
| R10 | C17 | C14 | coref-ident | Expression of TCL1,expression of TCL1 |
| R11 | C19 | C16 | coref-other | A-T patients containing the primary translocation alone,A-T patients |
| R12 | C20 | C18 | coref-ident | TCL1,TCL1 |
| R13 | C22 | C21 | coref-appos | MTCP1,a second gene |
| R14 | C23 | C19 | coref-other | A-T patients with t(X;14) translocations,A-T patients containing the primary translocation alone |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 25-38 | DNA_domain_or_region | denotes | TCL1 oncogene |
| T2 | 74-85 | DNA_domain_or_region | denotes | MTCP1/c6.1B |
| T3 | 104-125 | cell_type | denotes | non-leukaemic T cells |
| T4 | 131-161 | multi_cell | denotes | ataxia telangiectasia patients |
| T5 | 163-171 | multi_cell | denotes | Patients |
| T6 | 212-233 | other_name | denotes | ataxia telangiectasia |
| T7 | 235-238 | other_name | denotes | A-T |
| T8 | 270-295 | DNA_domain_or_region | denotes | chromosome translocations |
| T9 | 328-346 | cell_type | denotes | peripheral T cells |
| T10 | 394-412 | other_name | denotes | leukaemia/lymphoma |
| T11 | 424-430 | cell_type | denotes | T cell |
| T12 | 444-463 | cell_type | denotes | translocation cells |
| T13 | 516-547 | other_name | denotes | T cell prolymphocytic leukaemia |
| T14 | 549-554 | other_name | denotes | T-PLL |
| T15 | 585-590 | other_name | denotes | T-PLL |
| T16 | 679-684 | other_name | denotes | T-PLL |
| T17 | 701-705 | multi_cell | denotes | non- |
| T18 | 705-708 | other_name | denotes | A-T |
| T19 | 748-752 | protein_molecule | denotes | TCL1 |
| T20 | 757-762 | DNA_domain_or_region | denotes | 14q32 |
| T21 | 771-796 | protein_molecule | denotes | c6.1B/MTCP1 A1 transcript |
| T22 | 798-805 | DNA_domain_or_region | denotes | at-Xq28 |
| T23 | 887-891 | protein_molecule | denotes | TCL1 |
| T24 | 902-919 | cell_type | denotes | leukaemic T cells |
| T25 | 925-928 | other_name | denotes | A-T |
| T26 | 943-956 | DNA_molecule | denotes | chromosome 14 |
| T27 | 987-991 | protein_molecule | denotes | TCL1 |
| T28 | 1011-1035 | cell_type | denotes | preleukaemic clone cells |
| T29 | 1039-1042 | other_name | denotes | A-T |
| T30 | 1115-1119 | protein_molecule | denotes | TCL1 |
| T31 | 1164-1167 | other_name | denotes | A-T |
| T32 | 1292-1305 | RNA_molecule | denotes | B1 transcript |
| T33 | 1326-1331 | DNA_domain_or_region | denotes | MTCP1 |
| T34 | 1381-1386 | other_name | denotes | T-PLL |
| T35 | 1400-1403 | other_name | denotes | A-T |
| T36 | 1453-1458 | DNA_domain_or_region | denotes | MTCP1 |
| T37 | 1542-1545 | other_name | denotes | A-T |
| T38 | 1550-1554 | multi_cell | denotes | non- |
| T39 | 1554-1557 | other_name | denotes | A-T |