
PubMed:8566951
Annnotations
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
TextSentencer_T1 | 0-128 | Sentence | denotes | Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map more than 130 kb from SOX9. |
TextSentencer_T2 | 129-255 | Sentence | denotes | Campomelic dysplasia (CMPD1) and autosomal XY sex reversal (SRA1) are caused by mutations in the SRY-related gene SOX9 on 17q. |
TextSentencer_T3 | 256-389 | Sentence | denotes | Unexpectedly, the 17q breakpoints in four CMPD1 translocation cases previously analyzed by us and others map 50 kb or more from SOX9. |
TextSentencer_T4 | 390-501 | Sentence | denotes | Here, we present clinical, cytogenetic, and molecular data from a new CMPD1/SRA1 patient with t(6;17)(q14;q24). |
TextSentencer_T5 | 502-687 | Sentence | denotes | Fluorescence in situ hybridization has shown that the 17q breakpoint in this case maps to the same region as the breakpoints in the other translocation cases, at least 130 kb from SOX9. |
TextSentencer_T6 | 688-876 | Sentence | denotes | Likewise, the breakpoints in two of the previously described cases also map more than 130 kb and, as shown by pulsed field gel electrophoresis analysis, at most 400 kb or 690 kb from SOX9. |
TextSentencer_T7 | 877-1092 | Sentence | denotes | By using a SOX9 coding sequence polymorphism, expression of both SOX9 alleles has been demonstrated by the reverse transcriptase polymerase chain reaction in lymphoblastoid cells from one of the translocation cases. |
T1 | 0-128 | Sentence | denotes | Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map more than 130 kb from SOX9. |
T2 | 129-255 | Sentence | denotes | Campomelic dysplasia (CMPD1) and autosomal XY sex reversal (SRA1) are caused by mutations in the SRY-related gene SOX9 on 17q. |
T3 | 256-389 | Sentence | denotes | Unexpectedly, the 17q breakpoints in four CMPD1 translocation cases previously analyzed by us and others map 50 kb or more from SOX9. |
T4 | 390-501 | Sentence | denotes | Here, we present clinical, cytogenetic, and molecular data from a new CMPD1/SRA1 patient with t(6;17)(q14;q24). |
T5 | 502-687 | Sentence | denotes | Fluorescence in situ hybridization has shown that the 17q breakpoint in this case maps to the same region as the breakpoints in the other translocation cases, at least 130 kb from SOX9. |
T6 | 688-876 | Sentence | denotes | Likewise, the breakpoints in two of the previously described cases also map more than 130 kb and, as shown by pulsed field gel electrophoresis analysis, at most 400 kb or 690 kb from SOX9. |
T7 | 877-1092 | Sentence | denotes | By using a SOX9 coding sequence polymorphism, expression of both SOX9 alleles has been demonstrated by the reverse transcriptase polymerase chain reaction in lymphoblastoid cells from one of the translocation cases. |
DisGeNET
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T0 | 123-127 | gene:6662 | denotes | SOX9 |
T1 | 49-69 | disease:C1861922 | denotes | campomelic dysplasia |
T2 | 384-388 | gene:6662 | denotes | SOX9 |
T3 | 298-303 | disease:C1861922 | denotes | CMPD1 |
R1 | T0 | T1 | associated_with | SOX9,campomelic dysplasia |
R2 | T2 | T3 | associated_with | SOX9,CMPD1 |
jnlpba-st-training
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-25 | DNA | denotes | Translocation breakpoints |
T2 | 123-127 | DNA | denotes | SOX9 |
T3 | 226-242 | DNA | denotes | SRY-related gene |
T4 | 243-247 | DNA | denotes | SOX9 |
T5 | 251-254 | DNA | denotes | 17q |
T6 | 274-289 | DNA | denotes | 17q breakpoints |
T7 | 384-388 | DNA | denotes | SOX9 |
T8 | 484-500 | DNA | denotes | t(6;17)(q14;q24) |
T9 | 556-570 | DNA | denotes | 17q breakpoint |
T10 | 682-686 | DNA | denotes | SOX9 |
T11 | 871-875 | DNA | denotes | SOX9 |
T12 | 888-921 | DNA | denotes | SOX9 coding sequence polymorphism |
T13 | 942-946 | DNA | denotes | SOX9 |
T14 | 984-1005 | protein | denotes | reverse transcriptase |
T15 | 1035-1055 | cell_type | denotes | lymphoblastoid cells |
DisGeNET5_gene_disease
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
8566951-0#123#127#gene6662 | 123-127 | gene6662 | denotes | SOX9 |
8566951-0#49#69#diseaseC1861922 | 49-69 | diseaseC1861922 | denotes | campomelic dysplasia |
8566951-1#60#64#gene10011 | 189-193 | gene10011 | denotes | SRA1 |
8566951-1#97#100#gene6736 | 226-229 | gene6736 | denotes | SRY |
8566951-1#0#20#diseaseC1861922 | 129-149 | diseaseC1861922 | denotes | Campomelic dysplasia |
8566951-1#22#27#diseaseC1861922 | 151-156 | diseaseC1861922 | denotes | CMPD1 |
8566951-1#0#20#diseaseC1861922 | 129-149 | diseaseC1861922 | denotes | Campomelic dysplasia |
8566951-1#22#27#diseaseC1861922 | 151-156 | diseaseC1861922 | denotes | CMPD1 |
123#127#gene666249#69#diseaseC1861922 | 8566951-0#123#127#gene6662 | 8566951-0#49#69#diseaseC1861922 | associated_with | SOX9,campomelic dysplasia |
60#64#gene100110#20#diseaseC1861922 | 8566951-1#60#64#gene10011 | 8566951-1#0#20#diseaseC1861922 | associated_with | SRA1,Campomelic dysplasia |
60#64#gene1001122#27#diseaseC1861922 | 8566951-1#60#64#gene10011 | 8566951-1#22#27#diseaseC1861922 | associated_with | SRA1,CMPD1 |
60#64#gene100110#20#diseaseC1861922 | 8566951-1#60#64#gene10011 | 8566951-1#0#20#diseaseC1861922 | associated_with | SRA1,Campomelic dysplasia |
60#64#gene1001122#27#diseaseC1861922 | 8566951-1#60#64#gene10011 | 8566951-1#22#27#diseaseC1861922 | associated_with | SRA1,CMPD1 |
97#100#gene67360#20#diseaseC1861922 | 8566951-1#97#100#gene6736 | 8566951-1#0#20#diseaseC1861922 | associated_with | SRY,Campomelic dysplasia |
97#100#gene673622#27#diseaseC1861922 | 8566951-1#97#100#gene6736 | 8566951-1#22#27#diseaseC1861922 | associated_with | SRY,CMPD1 |
97#100#gene67360#20#diseaseC1861922 | 8566951-1#97#100#gene6736 | 8566951-1#0#20#diseaseC1861922 | associated_with | SRY,Campomelic dysplasia |
97#100#gene673622#27#diseaseC1861922 | 8566951-1#97#100#gene6736 | 8566951-1#22#27#diseaseC1861922 | associated_with | SRY,CMPD1 |
pubmed-sentences-benchmark
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
S1 | 0-128 | Sentence | denotes | Translocation breakpoints in three patients with campomelic dysplasia and autosomal sex reversal map more than 130 kb from SOX9. |
S2 | 129-255 | Sentence | denotes | Campomelic dysplasia (CMPD1) and autosomal XY sex reversal (SRA1) are caused by mutations in the SRY-related gene SOX9 on 17q. |
S3 | 256-389 | Sentence | denotes | Unexpectedly, the 17q breakpoints in four CMPD1 translocation cases previously analyzed by us and others map 50 kb or more from SOX9. |
S4 | 390-501 | Sentence | denotes | Here, we present clinical, cytogenetic, and molecular data from a new CMPD1/SRA1 patient with t(6;17)(q14;q24). |
S5 | 502-687 | Sentence | denotes | Fluorescence in situ hybridization has shown that the 17q breakpoint in this case maps to the same region as the breakpoints in the other translocation cases, at least 130 kb from SOX9. |
S6 | 688-876 | Sentence | denotes | Likewise, the breakpoints in two of the previously described cases also map more than 130 kb and, as shown by pulsed field gel electrophoresis analysis, at most 400 kb or 690 kb from SOX9. |
S7 | 877-1092 | Sentence | denotes | By using a SOX9 coding sequence polymorphism, expression of both SOX9 alleles has been demonstrated by the reverse transcriptase polymerase chain reaction in lymphoblastoid cells from one of the translocation cases. |
genia-medco-coref
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
C1 | 49-69 | NP | denotes | campomelic dysplasia |
C2 | 74-96 | NP | denotes | autosomal sex reversal |
C3 | 123-127 | NP | denotes | SOX9 |
C4 | 129-157 | NP | denotes | Campomelic dysplasia (CMPD1) |
C5 | 162-194 | NP | denotes | autosomal XY sex reversal (SRA1) |
C7 | 251-254 | NP | denotes | 17q |
C6 | 222-254 | NP | denotes | the SRY-related gene SOX9 on 17q |
C8 | 270-360 | NP | denotes | the 17q breakpoints in four CMPD1 translocation cases previously analyzed by us and others |
C10 | 384-388 | NP | denotes | SOX9 |
C9 | 365-388 | NP | denotes | 50 kb or more from SOX9 |
C11 | 454-500 | NP | denotes | a new CMPD1/SRA1 patient with t(6;17)(q14;q24) |
C12 | 574-583 | NP | denotes | this case |
C13 | 592-607 | NP | denotes | the same region |
C14 | 611-659 | NP | denotes | the breakpoints in the other translocation cases |
C15 | 682-686 | NP | denotes | SOX9 |
C16 | 871-875 | NP | denotes | SOX9 |
R1 | C4 | C1 | coref-ident | Campomelic dysplasia (CMPD1),campomelic dysplasia |
R2 | C5 | C2 | coref-ident | autosomal XY sex reversal (SRA1),autosomal sex reversal |
R3 | C6 | C3 | coref-ident | the SRY-related gene SOX9 on 17q,SOX9 |
R4 | C10 | C6 | coref-ident | SOX9,the SRY-related gene SOX9 on 17q |
R5 | C12 | C11 | coref-ident | this case,a new CMPD1/SRA1 patient with t(6;17)(q14;q24) |
R6 | C13 | C9 | coref-ident | the same region,50 kb or more from SOX9 |
R7 | C14 | C8 | coref-ident | the breakpoints in the other translocation cases,the 17q breakpoints in four CMPD1 translocation cases previously analyzed by us and others |
R8 | C15 | C10 | coref-ident | SOX9,SOX9 |
R9 | C16 | C15 | coref-ident | SOX9,SOX9 |
GENIAcorpus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-25 | DNA_domain_or_region | denotes | Translocation breakpoints |
T2 | 35-43 | multi_cell | denotes | patients |
T3 | 49-69 | other_name | denotes | campomelic dysplasia |
T4 | 74-96 | other_name | denotes | autosomal sex reversal |
T5 | 111-117 | polynucleotide | denotes | 130 kb |
T6 | 123-127 | DNA_domain_or_region | denotes | SOX9 |
T7 | 129-149 | other_name | denotes | Campomelic dysplasia |
T8 | 151-156 | other_name | denotes | CMPD1 |
T9 | 162-187 | other_name | denotes | autosomal XY sex reversal |
T10 | 189-193 | other_name | denotes | SRA1 |
T11 | 226-242 | DNA_domain_or_region | denotes | SRY-related gene |
T12 | 243-247 | DNA_domain_or_region | denotes | SOX9 |
T13 | 251-254 | DNA_molecule | denotes | 17q |
T14 | 274-277 | DNA_molecule | denotes | 17q |
T15 | 298-303 | other_name | denotes | CMPD1 |
T16 | 365-370 | polynucleotide | denotes | 50 kb |
T17 | 384-388 | DNA_domain_or_region | denotes | SOX9 |
T18 | 460-465 | other_name | denotes | CMPD1 |
T19 | 465-470 | other_name | denotes | /SRA1 |
T20 | 484-500 | DNA_domain_or_region | denotes | t(6;17)(q14;q24) |
T21 | 502-536 | other_name | denotes | Fluorescence in situ hybridization |
T22 | 556-559 | DNA_molecule | denotes | 17q |
T23 | 640-659 | other_name | denotes | translocation cases |
T24 | 670-676 | polynucleotide | denotes | 130 kb |
T25 | 682-686 | DNA_domain_or_region | denotes | SOX9 |
T26 | 774-780 | polynucleotide | denotes | 130 kb |
T27 | 798-839 | other_name | denotes | pulsed field gel electrophoresis analysis |
T28 | 849-855 | polynucleotide | denotes | 400 kb |
T29 | 859-865 | polynucleotide | denotes | 690 kb |
T30 | 871-875 | DNA_domain_or_region | denotes | SOX9 |
T31 | 888-892 | DNA_domain_or_region | denotes | SOX9 |
T32 | 942-946 | DNA_domain_or_region | denotes | SOX9 |
T33 | 984-1005 | protein_molecule | denotes | reverse transcriptase |
T34 | 1035-1055 | cell_type | denotes | lymphoblastoid cells |
T35 | 1072-1091 | other_name | denotes | translocation cases |
PubCasesHPO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
AB1 | 175-187 | HP:0012245 | denotes | sex reversal |
TI1 | 84-96 | HP:0012245 | denotes | sex reversal |
PubCasesORDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
AB1 | 129-149 | ORDO:140 | denotes | Campomelic dysplasia |
TI1 | 49-69 | ORDO:140 | denotes | campomelic dysplasia |