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PubMed:8529657 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 65-103 protein denotes lymphoid-specific transcription factor
T2 104-110 protein denotes Oct-2a
T3 116-154 protein denotes lymphoid-specific transcription factor
T4 155-161 protein denotes Oct-2a
T5 175-209 protein denotes transcriptional activation domains
T6 239-249 protein denotes N-terminal
T7 254-272 protein denotes C-terminal regions
T8 348-364 protein denotes effector domains
T9 372-395 protein denotes GAL4 DNA-binding domain
T10 443-449 protein denotes Oct-2a
T11 518-534 protein denotes promoter factors
T12 555-565 protein denotes C-terminus
T13 585-602 protein denotes N-terminal domain
T14 663-687 DNA denotes simian virus 40 enhancer
T15 728-746 protein denotes activation domains
T16 904-914 protein denotes C-terminus
T17 918-924 protein denotes Oct-2a
T18 928-935 cell_type denotes B cells
T19 940-954 cell_type denotes lymphoid cells
T20 1021-1046 protein denotes B-cell-specific cofactors
T21 1067-1083 protein denotes effector domains
T22 1087-1093 protein denotes Oct-2a
T23 1243-1249 protein denotes Oct-2a
T24 1396-1402 protein denotes Oct-2a
T25 1473-1479 protein denotes Oct-2a

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-111 Sentence denotes Transcriptional activation and repression, two properties of the lymphoid-specific transcription factor Oct-2a.
S2 112-273 Sentence denotes The lymphoid-specific transcription factor Oct-2a contains two transcriptional activation domains which are located within the N-terminal and C-terminal regions.
S3 274-396 Sentence denotes To study their differential activation properties, we linked the isolated effector domains to the GAL4 DNA-binding domain.
S4 397-535 Sentence denotes We have shown that both activating regions of Oct-2a, isolated from their natural context, can activate transcription as promoter factors.
S5 536-688 Sentence denotes In contrast to the C-terminus, activation by the N-terminal domain is dependent on a yet unidentified factor(s) binding to the simian virus 40 enhancer.
S6 689-828 Sentence denotes The results obtained by duplication of activation domains or their mixed combination suggest that the domains are functionally independent.
S7 829-936 Sentence denotes However, activation from a remote position could only be achieved with the C-terminus of Oct-2a in B cells.
S8 937-1174 Sentence denotes In lymphoid cells, higher activation levels were observed, suggesting that distinct B-cell-specific cofactors in concert with the effector domains of Oct-2a might be involved in mediating transcription from proximal and remote positions.
S9 1175-1250 Sentence denotes Furthermore, we identified a repression domain at the N-terminus of Oct-2a.
S10 1251-1345 Sentence denotes When transferred to a potent activator, transcriptional stimulation was inhibited efficiently.
S11 1346-1528 Sentence denotes These results underscore the modular structure of Oct-2a with separable domains for activation and repression and suggest that Oct-2a might have complex regulatory functions in vivo.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-41 NP denotes Transcriptional activation and repression
C3 61-110 NP denotes the lymphoid-specific transcription factor Oct-2a
C2 43-110 NP denotes two properties of the lymphoid-specific transcription factor Oct-2a
C4 112-161 NP denotes The lymphoid-specific transcription factor Oct-2a
C6 171-209 NP denotes two transcriptional activation domains
C7 210-215 NP denotes which
C8 235-272 NP denotes the N-terminal and C-terminal regions
C5 171-272 NP denotes two transcriptional activation domains which are located within the N-terminal and C-terminal regions
C9 283-288 NP denotes their
C11 443-449 NP denotes Oct-2a
C10 416-449 NP denotes both activating regions of Oct-2a
C12 465-470 NP denotes their
C13 551-565 NP denotes the C-terminus
C14 581-602 NP denotes the N-terminal domain
C15 728-746 NP denotes activation domains
C16 750-755 NP denotes their
C17 787-798 NP denotes the domains
C19 918-924 NP denotes Oct-2a
C18 900-924 NP denotes the C-terminus of Oct-2a
C20 1087-1093 NP denotes Oct-2a
C22 1243-1249 NP denotes Oct-2a
C21 1225-1249 NP denotes the N-terminus of Oct-2a
C23 1396-1402 NP denotes Oct-2a
C24 1473-1479 NP denotes Oct-2a
R1 C2 C1 coref-appos two properties of the lymphoid-specific transcription factor Oct-2a,Transcriptional activation and repression
R2 C4 C3 coref-ident The lymphoid-specific transcription factor Oct-2a,the lymphoid-specific transcription factor Oct-2a
R3 C7 C5 coref-relat which,two transcriptional activation domains which are located within the N-terminal and C-terminal regions
R4 C9 C6 coref-pron their,two transcriptional activation domains
R5 C11 C4 coref-ident Oct-2a,The lymphoid-specific transcription factor Oct-2a
R6 C10 C8 coref-ident both activating regions of Oct-2a,the N-terminal and C-terminal regions
R7 C12 C10 coref-pron their,both activating regions of Oct-2a
R8 C15 C6 coref-ident activation domains,two transcriptional activation domains
R9 C16 C15 coref-pron their,activation domains
R10 C17 C15 coref-ident the domains,activation domains
R11 C19 C11 coref-ident Oct-2a,Oct-2a
R12 C18 C13 coref-ident the C-terminus of Oct-2a,the C-terminus
R13 C20 C19 coref-ident Oct-2a,Oct-2a
R14 C22 C20 coref-ident Oct-2a,Oct-2a
R15 C21 C14 coref-ident the N-terminus of Oct-2a,the N-terminal domain
R16 C23 C22 coref-ident Oct-2a,Oct-2a
R17 C24 C23 coref-ident Oct-2a,Oct-2a

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-26 other_name denotes Transcriptional activation
T2 31-41 other_name denotes repression
T3 65-103 protein_family_or_group denotes lymphoid-specific transcription factor
T4 104-110 protein_molecule denotes Oct-2a
T5 116-154 protein_family_or_group denotes lymphoid-specific transcription factor
T6 155-161 protein_molecule denotes Oct-2a
T7 175-209 protein_domain_or_region denotes transcriptional activation domains
T8 239-249 protein_domain_or_region denotes N-terminal
T9 254-272 protein_domain_or_region denotes C-terminal regions
T10 348-364 protein_domain_or_region denotes effector domains
T11 372-395 protein_domain_or_region denotes GAL4 DNA-binding domain
T12 443-449 protein_molecule denotes Oct-2a
T13 518-534 protein_family_or_group denotes promoter factors
T14 555-565 protein_domain_or_region denotes C-terminus
T15 585-602 protein_domain_or_region denotes N-terminal domain
T16 663-687 DNA_domain_or_region denotes simian virus 40 enhancer
T17 728-746 protein_domain_or_region denotes activation domains
T18 904-914 protein_domain_or_region denotes C-terminus
T19 918-924 protein_molecule denotes Oct-2a
T20 928-935 cell_type denotes B cells
T21 940-954 cell_type denotes lymphoid cells
T22 1021-1046 protein_family_or_group denotes B-cell-specific cofactors
T23 1067-1083 protein_domain_or_region denotes effector domains
T24 1087-1093 protein_molecule denotes Oct-2a
T25 1125-1138 other_name denotes transcription
T26 1243-1249 protein_molecule denotes Oct-2a
T27 1273-1289 other_name denotes potent activator
T28 1291-1318 other_name denotes transcriptional stimulation
T29 1396-1402 protein_molecule denotes Oct-2a
T30 1473-1479 protein_molecule denotes Oct-2a
T31 1499-1519 other_name denotes regulatory functions